carbon monoxide has been researched along with Reperfusion Injury in 131 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbon monoxide (CO) can exert potent anti-inflammatory effects in animal and cell culture models of sepsis, despite well-known lethal effects at high concentration." | 8.84 | Cytoprotective and anti-inflammatory actions of carbon monoxide in organ injury and sepsis models. ( Choi, AM; Ryter, SW, 2007) |
| "The protective effects of carbon monoxide (CO) against ischemia/reperfusion (IR) injury during organ transplantation have been extensively investigated." | 8.12 | Luminal Administration of a Water-soluble Carbon Monoxide-releasing Molecule (CORM-3) Mitigates Ischemia/Reperfusion Injury in Rats Following Intestinal Transplantation. ( Aokage, T; Hirayama, T; Igawa, T; Ishikawa-Aoyama, M; Motterlini, R; Naito, H; Nakao, A; Nojima, T; Obara, T; Seya, M; Yamamoto, H, 2022) |
| "This study aimed to assess whether pretreatment with carbon monoxide-releasing molecule-2 (CORM-2) could ameliorate inflammation by regulating differentiation of CD4 + T cells in intestinal mucosa of rats undergoing hemorrhagic shock." | 8.12 | Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock. ( Du, F; Niu, Q; Wang, X; Yang, X, 2022) |
| "Carbon monoxide (CO) releasing molecule (CORM)-3, a water-soluble CORM, has protective effects against inflammatory and ischemia/reperfusion injury." | 7.91 | Carbon monoxide-releasing molecule-3 protects against cortical pyroptosis induced by hemorrhagic shock and resuscitation via mitochondrial regulation. ( Fu, L; Kong, XJ; Li, CC; Li, Y; Qi, MM; Song, PP; Wang, XD; Wang, XP; Zhang, DX; Zhang, LM, 2019) |
| "The endogenously produced gaseous molecule carbon monoxide is able to promote organ protection after ischemia-reperfusion injuries (IRI)." | 7.85 | The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats' retinal ganglion cells after ischemia and reperfusion injury. ( Biermann, J; Buerkle, H; Goebel, U; Hagmann, C; Romao, CC; Schallner, N; Ulbrich, F, 2017) |
| "Carbon monoxide (CO) exerts protective effects on hepatic ischemia/reperfusion injury (IRI), but the underlying molecular mechanisms are not fully understood." | 7.85 | Carbon monoxide ameliorates hepatic ischemia/reperfusion injury via sirtuin 1-mediated deacetylation of high-mobility group box 1 in rats. ( Dahmen, U; Dirsch, O; Dong, W; Guo, E; Hu, J; Jiang, X; Liu, A; Liu, S; Sun, J; Yang, J; Yang, Y, 2017) |
| "Carbon monoxide poisoning is one of the important emergency situations manifested by primarily acute and chronic anoxic central nervous system (CNS) injuries and other organ damages." | 7.83 | Possible role of antioxidants and nitric oxide inhibitors against carbon monoxide poisoning: Having a clear conscience because of their potential benefits. ( Adam, B; Akyol, O; Akyol, S; Erdemli, HK; Gulec, MA; Pehlivan, S; Yuksel, S, 2016) |
| "Lung ischemia-reperfusion injury (IRI) may be attenuated through carbon monoxide (CO)'s anti-inflammatory effect or hydrogen (H2)'s anti-oxidant effect." | 7.83 | Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats. ( Cui, X; Jiang, C; Kang, J; Liu, J; Liu, R; Ma, L; Meng, C; Niu, L; Xing, J; Zhou, H, 2016) |
| " Both nitrite and carbon monoxide (CO) may protect from this reperfusion injury by limiting mitochondrial free radial production." | 7.81 | Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine. ( Airgood, H; Dezfulian, C; Escobar, D; Gómez, H; Haugaa, H; Holder, A; Kenny, E; Maberry, DR; Ogundele, O; Pinsky, MR; Quintero, AM; Shiva, S; Tønnessen, TI; Zuckerbraun, B, 2015) |
| "To study the protective effect of carbon monoxide (CO) inhalation on the serious limb ischemia/reperfusion (I/R) injury, and which effects caused to shock in rats." | 7.77 | [Effects of carbon monoxide inhalation on severe limb ischemia/reperfusion injury and its damages lead to shock]. ( Qi, WZ; Shi, ZL; Zhao, J; Zhu, ZL, 2011) |
| "The perioperative administration of low-dose inhaled carbon monoxide decreases warm ischemia-reperfusion injury in lungs in miniature swine." | 7.76 | Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine. ( Oku, M; Okumi, M; Sahara, H; Samelson-Jones, E; Setoyama, K; Shimizu, A; Yamada, K, 2010) |
| "To study the protective effect of carbon monoxide(CO) inhalation in the limb ischemia/reperfusion (I/R) injury of rats." | 7.76 | [Carbon monoxide inhalation protects against limb ischemia/reperfusion injury]. ( Li, J; Qi, WZ; Shi, ZL; Zhu, ZL, 2010) |
| "The aim of this study is to investigate the effect of heme oxygenase-1 (HO-1)/carbon monoxide (CO) system in pulmonary ischemia-reperfusion injury (PIRI) in rabbits." | 7.75 | Role of heme oxygenase-1/carbon monoxide system in pulmonary ischemia-reperfusion injury. ( Jia, X; Lin, L; Shi, L; Wang, F; Wang, W, 2009) |
| "In previous work we have demonstrated that delivery of low concentrations (250 ppm) of carbon monoxide by means of inhalation to donors, recipients, or both protects transplanted lungs from ischemia-reperfusion injury (improved gas exchange, diminished intragraft and systemic inflammation, and retention of graft vascular endothelial cell ultrastructure)." | 7.74 | Carbon monoxide-saturated preservation solution protects lung grafts from ischemia-reperfusion injury. ( Kohmoto, J; McCurry, KR; Nakao, A; Sugimoto, R; Ueda, H; Wang, Y; Zhan, J, 2008) |
| " We postulated that elevated carbon monoxide concentrations in serum of smoking women inhibits apoptosis and debris shedding of trophoblast cells exposed to ischemia-reperfusion injury because carbon monoxide has cytoprotective effects on endothelial and smooth muscle cells in culture." | 7.73 | Carbon monoxide inhibits hypoxia/reoxygenation-induced apoptosis and secondary necrosis in syncytiotrophoblast. ( Bainbridge, SA; Belkacemi, L; Dickinson, M; Graham, CH; Smith, GN, 2006) |
| "A direct role of carbon monoxide (CO), an effector-signaling molecule during heme oxygenase-1 (HO-1) catalysis of heme, in the protection against hepatic ischemia/reperfusion (I/R) injury needs to be established." | 7.71 | Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway. ( Amersi, F; Anselmo, D; Buelow, R; Busuttil, RW; Iyer, S; Katori, M; Kupiec-Weglinski, JW; Melinek, J; Shen, XD; Southard, DJ; Volk, HD, 2002) |
| "Reperfusion-induced ventricular fibrillation (VF) and heme oxygenase (HO)-related carbon monoxide (CO) production in isolated ischemic/reperfused rat hearts were studied by gas chromatography." | 7.71 | The role of heme oxygenase-related carbon monoxide and ventricular fibrillation in ischemic/reperfused hearts. ( Bak, I; Joo, F; Papp, G; Szendrei, L; Tosaki, A; Turoczi, T; Varga, E; Vecsernyes, M, 2002) |
| "Carbon monoxide has a great potential in minimizing I/R injury." | 6.48 | Use of carbon monoxide in minimizing ischemia/reperfusion injury in transplantation. ( Kimura, S; Murase, N; Ozaki, KS, 2012) |
| "To investigate this, we created a hemorrhagic shock model rat, followed by resuscitation with RBC and CO-RBC." | 5.40 | Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats. ( Ishima, Y; Maruyama, T; Ogaki, S; Otagiri, M; Taguchi, K; Watanabe, H, 2014) |
| "Renal ischemia reperfusion injury (IRI) is a major factor responsible for acute renal failure." | 5.39 | 5-Aminolevulinic acid combined with ferrous iron induces carbon monoxide generation in mouse kidneys and protects from renal ischemia-reperfusion injury. ( Abe, F; Cai, S; Ding, Q; Fujino, M; Hou, J; Ito, H; Kitajima, Y; Li, XK; Takahashi, K; Tanaka, T, 2013) |
| "Carbon monoxide (CO) is an endogenous gaseous regulatory molecule, and exogenously delivered CO in low concentrations provides potent cytoprotection." | 5.36 | Ex vivo application of carbon monoxide in UW solution prevents transplant-induced renal ischemia/reperfusion injury in pigs. ( Castillo-Rama, M; Echeverri, GJ; Ekser, B; Ezzelarab, M; Faleo, G; Murase, N; Nakao, A; Nalesnik, MA; Ozaki, KS; Ross, MA; Stolz, DB; Ueki, S; Yoshida, J, 2010) |
| "As carbon monoxide (CO) has potent cytoprotective functions on vascular endothelial cells, this study examined if CO treatment of excised liver grafts during cold storage could protect SECs and ameliorate hepatic I/R injury." | 5.35 | Liver graft exposure to carbon monoxide during cold storage protects sinusoidal endothelial cells and ameliorates reperfusion injury in rats. ( Geller, DA; Ikeda, A; Murase, N; Nakao, A; Ross, MA; Stolz, DB; Tomiyama, K; Ueki, S, 2009) |
| "Renal ischemia/reperfusion injury is a major complication of kidney transplantation." | 5.35 | Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts. ( Choi, AM; Faleo, G; Kohmoto, J; McCurry, KR; Murase, N; Nakahira, K; Nakao, A; Shimizu, H; Sugimoto, R; Takahashi, T, 2008) |
| "Carbon monoxide (CO) can exert potent anti-inflammatory effects in animal and cell culture models of sepsis, despite well-known lethal effects at high concentration." | 4.84 | Cytoprotective and anti-inflammatory actions of carbon monoxide in organ injury and sepsis models. ( Choi, AM; Ryter, SW, 2007) |
| "The protective effects of carbon monoxide (CO) against ischemia/reperfusion (IR) injury during organ transplantation have been extensively investigated." | 4.12 | Luminal Administration of a Water-soluble Carbon Monoxide-releasing Molecule (CORM-3) Mitigates Ischemia/Reperfusion Injury in Rats Following Intestinal Transplantation. ( Aokage, T; Hirayama, T; Igawa, T; Ishikawa-Aoyama, M; Motterlini, R; Naito, H; Nakao, A; Nojima, T; Obara, T; Seya, M; Yamamoto, H, 2022) |
| "This study aimed to assess whether pretreatment with carbon monoxide-releasing molecule-2 (CORM-2) could ameliorate inflammation by regulating differentiation of CD4 + T cells in intestinal mucosa of rats undergoing hemorrhagic shock." | 4.12 | Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock. ( Du, F; Niu, Q; Wang, X; Yang, X, 2022) |
| "Carbon monoxide (CO) releasing molecule (CORM)-3, a water-soluble CORM, has protective effects against inflammatory and ischemia/reperfusion injury." | 3.91 | Carbon monoxide-releasing molecule-3 protects against cortical pyroptosis induced by hemorrhagic shock and resuscitation via mitochondrial regulation. ( Fu, L; Kong, XJ; Li, CC; Li, Y; Qi, MM; Song, PP; Wang, XD; Wang, XP; Zhang, DX; Zhang, LM, 2019) |
| "The endogenously produced gaseous molecule carbon monoxide is able to promote organ protection after ischemia-reperfusion injuries (IRI)." | 3.85 | The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats' retinal ganglion cells after ischemia and reperfusion injury. ( Biermann, J; Buerkle, H; Goebel, U; Hagmann, C; Romao, CC; Schallner, N; Ulbrich, F, 2017) |
| "Carbon monoxide (CO) exerts protective effects on hepatic ischemia/reperfusion injury (IRI), but the underlying molecular mechanisms are not fully understood." | 3.85 | Carbon monoxide ameliorates hepatic ischemia/reperfusion injury via sirtuin 1-mediated deacetylation of high-mobility group box 1 in rats. ( Dahmen, U; Dirsch, O; Dong, W; Guo, E; Hu, J; Jiang, X; Liu, A; Liu, S; Sun, J; Yang, J; Yang, Y, 2017) |
| "Carbon monoxide poisoning is one of the important emergency situations manifested by primarily acute and chronic anoxic central nervous system (CNS) injuries and other organ damages." | 3.83 | Possible role of antioxidants and nitric oxide inhibitors against carbon monoxide poisoning: Having a clear conscience because of their potential benefits. ( Adam, B; Akyol, O; Akyol, S; Erdemli, HK; Gulec, MA; Pehlivan, S; Yuksel, S, 2016) |
| "Carbon monoxide (CO) attenuates lung ischemia reperfusion injury (IRI) via inhalation, and as an additive dissolved in flush/preservation solution." | 3.83 | Inflation with carbon monoxide in rat donor lung during cold ischemia phase ameliorates graft injury. ( Cui, X; Liu, J; Liu, R; Ma, L; Meng, C; Xing, J; Zhou, H, 2016) |
| "Lung ischemia-reperfusion injury (IRI) may be attenuated through carbon monoxide (CO)'s anti-inflammatory effect or hydrogen (H2)'s anti-oxidant effect." | 3.83 | Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats. ( Cui, X; Jiang, C; Kang, J; Liu, J; Liu, R; Ma, L; Meng, C; Niu, L; Xing, J; Zhou, H, 2016) |
| " Both nitrite and carbon monoxide (CO) may protect from this reperfusion injury by limiting mitochondrial free radial production." | 3.81 | Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine. ( Airgood, H; Dezfulian, C; Escobar, D; Gómez, H; Haugaa, H; Holder, A; Kenny, E; Maberry, DR; Ogundele, O; Pinsky, MR; Quintero, AM; Shiva, S; Tønnessen, TI; Zuckerbraun, B, 2015) |
| "Administration of carbon monoxide to the deceased donor and non-heart-beating donor lungs reduces ischemia-reperfusion injury in rat lungs transplanted from non-heart-beating donors." | 3.79 | Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors. ( Dong, B; Egan, TM; Stewart, PW, 2013) |
| "To study the protective effect of carbon monoxide (CO) inhalation on the serious limb ischemia/reperfusion (I/R) injury, and which effects caused to shock in rats." | 3.77 | [Effects of carbon monoxide inhalation on severe limb ischemia/reperfusion injury and its damages lead to shock]. ( Qi, WZ; Shi, ZL; Zhao, J; Zhu, ZL, 2011) |
| "To study the protective effect of carbon monoxide(CO) inhalation in the limb ischemia/reperfusion (I/R) injury of rats." | 3.76 | [Carbon monoxide inhalation protects against limb ischemia/reperfusion injury]. ( Li, J; Qi, WZ; Shi, ZL; Zhu, ZL, 2010) |
| "The perioperative administration of low-dose inhaled carbon monoxide decreases warm ischemia-reperfusion injury in lungs in miniature swine." | 3.76 | Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine. ( Oku, M; Okumi, M; Sahara, H; Samelson-Jones, E; Setoyama, K; Shimizu, A; Yamada, K, 2010) |
| "The aim of this study is to investigate the effect of heme oxygenase-1 (HO-1)/carbon monoxide (CO) system in pulmonary ischemia-reperfusion injury (PIRI) in rabbits." | 3.75 | Role of heme oxygenase-1/carbon monoxide system in pulmonary ischemia-reperfusion injury. ( Jia, X; Lin, L; Shi, L; Wang, F; Wang, W, 2009) |
| "Nitric oxide and carbon monoxide exert vasodilatory effects that minimize ischaemia-reperfusion injury." | 3.74 | Application of nitric oxide and carbon monoxide in a model of renal preservation. ( Bagul, A; Gadepalli, RS; Hosgood, SA; Kaushik, M; Nicholson, ML; Rimoldi, J, 2008) |
| "In previous work we have demonstrated that delivery of low concentrations (250 ppm) of carbon monoxide by means of inhalation to donors, recipients, or both protects transplanted lungs from ischemia-reperfusion injury (improved gas exchange, diminished intragraft and systemic inflammation, and retention of graft vascular endothelial cell ultrastructure)." | 3.74 | Carbon monoxide-saturated preservation solution protects lung grafts from ischemia-reperfusion injury. ( Kohmoto, J; McCurry, KR; Nakao, A; Sugimoto, R; Ueda, H; Wang, Y; Zhan, J, 2008) |
| " We postulated that elevated carbon monoxide concentrations in serum of smoking women inhibits apoptosis and debris shedding of trophoblast cells exposed to ischemia-reperfusion injury because carbon monoxide has cytoprotective effects on endothelial and smooth muscle cells in culture." | 3.73 | Carbon monoxide inhibits hypoxia/reoxygenation-induced apoptosis and secondary necrosis in syncytiotrophoblast. ( Bainbridge, SA; Belkacemi, L; Dickinson, M; Graham, CH; Smith, GN, 2006) |
| "Reperfusion-induced ventricular fibrillation (VF) and heme oxygenase (HO)-related carbon monoxide (CO) production in isolated ischemic/reperfused rat hearts were studied by gas chromatography." | 3.71 | The role of heme oxygenase-related carbon monoxide and ventricular fibrillation in ischemic/reperfused hearts. ( Bak, I; Joo, F; Papp, G; Szendrei, L; Tosaki, A; Turoczi, T; Varga, E; Vecsernyes, M, 2002) |
| "A direct role of carbon monoxide (CO), an effector-signaling molecule during heme oxygenase-1 (HO-1) catalysis of heme, in the protection against hepatic ischemia/reperfusion (I/R) injury needs to be established." | 3.71 | Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway. ( Amersi, F; Anselmo, D; Buelow, R; Busuttil, RW; Iyer, S; Katori, M; Kupiec-Weglinski, JW; Melinek, J; Shen, XD; Southard, DJ; Volk, HD, 2002) |
| "Carbon monoxide (CO) was historically regarded solely as a poisonous gas that binds to hemoglobin and reduces oxygen-carrying capacity of blood at high concentrations." | 2.72 | Application of carbon monoxide in kidney and heart transplantation: A novel pharmacological strategy for a broader use of suboptimal renal and cardiac grafts. ( Alornyo, KK; Dugbartey, GJ; Luke, PPW; Sener, A, 2021) |
| "Carbon monoxide has a great potential in minimizing I/R injury." | 2.48 | Use of carbon monoxide in minimizing ischemia/reperfusion injury in transplantation. ( Kimura, S; Murase, N; Ozaki, KS, 2012) |
| "Although many diseases, including cancer, hematological diseases, hypertension, heart failure, inflammation, sepsis, neurodegeneration, and sleep disorders, have been linked to abnormal endogenous CO metabolism and functions, CO administration has therapeutic potential in inflammation, sepsis, lung injury, cardiovascular diseases, transplantation, and cancer." | 2.48 | Carbon monoxide: an unusual drug. ( Ascenzi, P; di Masi, A; Gullotta, F, 2012) |
| "Ischemia reperfusion injury (IRI) is the predominant tissue insult associated with organ transplantation." | 1.48 | Carbon monoxide protects the kidney through the central circadian clock and CD39. ( Câmara, NOS; Correa-Costa, M; Csizmadia, E; Gallo, D; Gomperts, E; Hauser, CJ; Ji, X; Lieberum, JL; Otterbein, LE; Robson, SC; Wang, B, 2018) |
| "To investigate this, we created a hemorrhagic shock model rat, followed by resuscitation with RBC and CO-RBC." | 1.40 | Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats. ( Ishima, Y; Maruyama, T; Ogaki, S; Otagiri, M; Taguchi, K; Watanabe, H, 2014) |
| "Carbon monoxide (CO) is an endogenous gaseous transmitter that exerts multi-protection in ischemia/reperfusion (I/R) injury, but few experimental studies regarding CO on myocardial I/R-induced apoptosis, as well as its underlying mechanism have been conducted." | 1.40 | Carbon monoxide releasing molecule‑2 attenuated ischemia/reperfusion‑induced apoptosis in cardiomyocytes via a mitochondrial pathway. ( Chen, C; Chen, F; Fang, X; He, Y; Huang, Z; Li, H; Lin, Q; Zhao, S, 2014) |
| "Renal ischemia reperfusion injury (IRI) is a major factor responsible for acute renal failure." | 1.39 | 5-Aminolevulinic acid combined with ferrous iron induces carbon monoxide generation in mouse kidneys and protects from renal ischemia-reperfusion injury. ( Abe, F; Cai, S; Ding, Q; Fujino, M; Hou, J; Ito, H; Kitajima, Y; Li, XK; Takahashi, K; Tanaka, T, 2013) |
| "Carbon monoxide (CO) is an accepted cytoprotective molecule." | 1.39 | Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway. ( Biermann, J; Buerkle, H; Goebel, U; Lagrèze, WA; Loop, T; Otterbein, LE; Romão, CC; Schallner, N, 2013) |
| "Ischemia and reperfusion injury (I/R) of neuronal structures and organs is associated with increased morbidity and mortality due to neuronal cell death." | 1.38 | Postconditioning with inhaled carbon monoxide counteracts apoptosis and neuroinflammation in the ischemic rat retina. ( Biermann, J; Buerkle, H; Fuchs, M; Goebel, U; Lagrèze, WA; Loop, T; Schallner, N; Schwer, CI; van Oterendorp, C, 2012) |
| "The process of brain death can induce acute lung injury in donors and aggravate ischemia-reperfusion injury in grafts." | 1.37 | Protection against lung graft injury from brain-dead donors with carbon monoxide, biliverdin, or both. ( Ding, W; Jin, D; Li, W; Liu, J; Pan, P; Qian, H; Wang, J; Zhou, H; Zhu, D, 2011) |
| "Carbon monoxide (CO) is an endogenous gaseous regulatory molecule, and exogenously delivered CO in low concentrations provides potent cytoprotection." | 1.36 | Ex vivo application of carbon monoxide in UW solution prevents transplant-induced renal ischemia/reperfusion injury in pigs. ( Castillo-Rama, M; Echeverri, GJ; Ekser, B; Ezzelarab, M; Faleo, G; Murase, N; Nakao, A; Nalesnik, MA; Ozaki, KS; Ross, MA; Stolz, DB; Ueki, S; Yoshida, J, 2010) |
| "As carbon monoxide (CO) has potent cytoprotective functions on vascular endothelial cells, this study examined if CO treatment of excised liver grafts during cold storage could protect SECs and ameliorate hepatic I/R injury." | 1.35 | Liver graft exposure to carbon monoxide during cold storage protects sinusoidal endothelial cells and ameliorates reperfusion injury in rats. ( Geller, DA; Ikeda, A; Murase, N; Nakao, A; Ross, MA; Stolz, DB; Tomiyama, K; Ueki, S, 2009) |
| "Renal ischemia/reperfusion injury is a major complication of kidney transplantation." | 1.35 | Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts. ( Choi, AM; Faleo, G; Kohmoto, J; McCurry, KR; Murase, N; Nakahira, K; Nakao, A; Shimizu, H; Sugimoto, R; Takahashi, T, 2008) |
| "For testing this hypothesis ischemic acute renal failure was induced in rats by 40 min of clamping of the left renal artery after right-sided nephrectomy." | 1.33 | Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure. ( Amann, K; Arend, M; Bernhardt, WM; Câmpean, V; Eckardt, KU; Günzler, V; Jürgensen, JS; Kany, S; Klaus, S; Warnecke, C; Weidemann, A; Wiesener, MS; Willam, C, 2006) |
| "Current dogma associates reperfusion injury with the introduction of reactive oxygen species (ROS) into the ischemic tissue." | 1.28 | Physiological targets of superoxide anion and hydrogen peroxide in reperfusion injury. ( Brüne, B; Busse, R; Hecker, G; Mülsch, A; Schmidt, KU; Ullrich, V, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.76) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 59 (45.04) | 29.6817 |
| 2010's | 63 (48.09) | 24.3611 |
| 2020's | 8 (6.11) | 2.80 |
| Authors | Studies |
|---|---|
| Dugbartey, GJ | 2 |
| Alornyo, KK | 1 |
| Luke, PPW | 3 |
| Sener, A | 2 |
| Obara, T | 1 |
| Yamamoto, H | 1 |
| Aokage, T | 1 |
| Igawa, T | 1 |
| Nojima, T | 1 |
| Hirayama, T | 1 |
| Seya, M | 1 |
| Ishikawa-Aoyama, M | 1 |
| Nakao, A | 17 |
| Motterlini, R | 5 |
| Naito, H | 1 |
| Nagasaki, T | 1 |
| Maeda, H | 2 |
| Taguchi, K | 2 |
| Yanagisawa, H | 1 |
| Nishida, K | 1 |
| Kobayashi, K | 1 |
| Wada, N | 1 |
| Noguchi, I | 1 |
| Murata, R | 1 |
| Sakai, H | 1 |
| Kitagishi, H | 1 |
| Saruwatari, J | 1 |
| Watanabe, H | 2 |
| Otagiri, M | 2 |
| Maruyama, T | 2 |
| Kwong, AM | 1 |
| Bhattacharjee, RN | 2 |
| Ye, M | 1 |
| Tan, Q | 1 |
| Jiang, D | 1 |
| Li, J | 3 |
| Yao, C | 1 |
| Zhou, Y | 1 |
| Niu, Q | 3 |
| Du, F | 3 |
| Yang, X | 6 |
| Wang, X | 4 |
| Abuchowski, A | 1 |
| Cheng, Y | 1 |
| Rong, J | 1 |
| Maignan, M | 2 |
| Gennai, S | 3 |
| Debaty, G | 2 |
| Romanini, D | 2 |
| Schmidt, MH | 1 |
| Brenckmann, V | 1 |
| Brouta, A | 2 |
| Ventrillard, I | 2 |
| Briot, R | 3 |
| Ulbrich, F | 3 |
| Hagmann, C | 1 |
| Buerkle, H | 3 |
| Romao, CC | 2 |
| Schallner, N | 3 |
| Goebel, U | 6 |
| Biermann, J | 6 |
| Stifter, J | 1 |
| Böhringer, D | 2 |
| Lagrèze, WA | 5 |
| Correa-Costa, M | 1 |
| Gallo, D | 3 |
| Csizmadia, E | 2 |
| Gomperts, E | 1 |
| Lieberum, JL | 1 |
| Hauser, CJ | 1 |
| Ji, X | 1 |
| Wang, B | 1 |
| Câmara, NOS | 1 |
| Robson, SC | 1 |
| Otterbein, LE | 11 |
| Richard-Mohamed, M | 1 |
| Sun, Q | 1 |
| Haig, A | 1 |
| Aboalsamh, G | 1 |
| Barrett, P | 1 |
| Mayer, R | 1 |
| Alhasan, I | 1 |
| Pineda-Solis, K | 1 |
| Jiang, L | 1 |
| Alharbi, H | 1 |
| Saha, M | 1 |
| Patterson, E | 1 |
| Cepinskas, G | 1 |
| Jevnikar, AM | 1 |
| Murokawa, T | 1 |
| Sahara, H | 2 |
| Sekijima, M | 1 |
| Pomposelli, T | 1 |
| Iwanaga, T | 1 |
| Ichinari, Y | 1 |
| Shimizu, A | 2 |
| Yamada, K | 2 |
| Zhang, LM | 1 |
| Zhang, DX | 1 |
| Fu, L | 1 |
| Li, Y | 1 |
| Wang, XP | 1 |
| Qi, MM | 1 |
| Li, CC | 1 |
| Song, PP | 1 |
| Wang, XD | 1 |
| Kong, XJ | 1 |
| Ryter, SW | 8 |
| Choi, AM | 16 |
| Loop, T | 2 |
| Liao, YF | 1 |
| Zhu, W | 1 |
| Li, DP | 1 |
| Zhu, X | 1 |
| Hou, J | 1 |
| Cai, S | 1 |
| Kitajima, Y | 1 |
| Fujino, M | 1 |
| Ito, H | 1 |
| Takahashi, K | 1 |
| Abe, F | 1 |
| Tanaka, T | 1 |
| Ding, Q | 1 |
| Li, XK | 1 |
| Tong, L | 1 |
| Cai, M | 1 |
| Huang, Y | 1 |
| Zhang, H | 1 |
| Su, B | 1 |
| Li, Z | 1 |
| Dong, H | 1 |
| Zhao, S | 1 |
| Lin, Q | 1 |
| Li, H | 1 |
| He, Y | 1 |
| Fang, X | 1 |
| Chen, F | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091] | Phase 2 | 20 participants (Anticipated) | Interventional | 2019-08-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
28 reviews available for carbon monoxide and Reperfusion Injury
| Article | Year |
|---|---|
Application of carbon monoxide in kidney and heart transplantation: A novel pharmacological strategy for a broader use of suboptimal renal and cardiac grafts.
Topics: Animals; Carbon Monoxide; Cold Ischemia; Heart Transplantation; Humans; Kidney Transplantation; Repe | 2021 |
Emerging role of carbon monoxide in intestinal transplantation.
Topics: Animals; Carbon Monoxide; Cold Ischemia; Diffusion of Innovation; Graft Survival; Humans; Intestines | 2021 |
Carbon monoxide mechanism of protection against renal ischemia and reperfusion injury.
Topics: Anti-Inflammatory Agents; Carbon Monoxide; Humans; Ischemia; Kidney Diseases; Reperfusion Injury | 2022 |
Therapeutic Potential of Heme Oxygenase-1/carbon Monoxide System Against Ischemia-Reperfusion Injury.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Cytokines; Heme Oxygenase-1; Humans; Oxidative S | 2017 |
Carbon monoxide in exhaled breath testing and therapeutics.
Topics: Acute Lung Injury; Anesthesia; Animals; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Cystic Fi | 2013 |
Heme oxygenase-1 and gut ischemia/reperfusion injury: A short review.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase-1; Humans; Intestines; Iron; | 2013 |
[Ischemia-reperfusion injury after lung transplantation].
Topics: Adenosine Triphosphate; Apoptosis; Bronchodilator Agents; Calcium; Carbon Monoxide; Cytokines; Human | 2014 |
Therapeutic roles of carbon monoxide in intestinal ischemia-reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Heme; Heme Oxygenase-1; Humans; Intestinal Disea | 2015 |
Localized delivery of carbon monoxide.
Topics: Administration, Cutaneous; Administration, Inhalation; Administration, Oral; Animals; Biliverdine; C | 2017 |
Hemoxygenase-1 in cardiovascular disease.
Topics: Animals; Antioxidants; Bilirubin; Carbon Monoxide; Cardiovascular Diseases; Diabetes Mellitus; Heme | 2008 |
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease.
Topics: Animals; Apoptosis; Biliverdine; Carbon Monoxide; Cell Proliferation; Heme; Heme Oxygenase-1; Humans | 2009 |
Carbon monoxide: endogenous mediator, potential diagnostic and therapeutic target.
Topics: Animals; Biomarkers; Carbon Monoxide; Cardiovascular Diseases; Exhalation; Gene Expression; Heme Oxy | 2010 |
Hemeoxygenase-1 and renal ischaemia-reperfusion injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Biliverdine; Carbon Monoxide; Heme Oxygenase-1; Humans; Kid | 2010 |
Use of carbon monoxide in minimizing ischemia/reperfusion injury in transplantation.
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Carbon Monoxide Poisoning; Heme Oxygenase (Dec | 2012 |
Role of medullary blood flow in the pathogenesis of renal ischemia-reperfusion injury.
Topics: Acute Kidney Injury; Angiopoietin-1; Animals; Atrial Natriuretic Factor; Carbon Monoxide; Heme Oxyge | 2012 |
Carbon monoxide in acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Carbon Monoxide; Humans; Hyperoxia; Lung Trans | 2012 |
Carbon monoxide and the pancreas.
Topics: Animals; Carbon Monoxide; Heme Oxygenase (Decyclizing); Humans; Hyperglycemia; Pancreas; Pancreatiti | 2012 |
Carbon monoxide: an unusual drug.
Topics: Animals; Carbon Monoxide; Cardiovascular Diseases; Enzyme Induction; Heme Oxygenase-1; Humans; Infla | 2012 |
The social network of carbon monoxide in medicine.
Topics: Carbon Monoxide; Heme Oxygenase-1; Humans; Immunity, Innate; Reperfusion Injury; Sepsis | 2013 |
A novel strategy against ischemia and reperfusion injury: cytoprotection with heme oxygenase system.
Topics: Animals; Biliverdine; Carbon Monoxide; Cytoprotection; Enzyme Induction; Free Radicals; Heme; Heme O | 2002 |
Heme oxygenase system in ischemia and reperfusion injury.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Enzyme Induction; Ferritins; Heme; Heme Oxygenase | 2004 |
Therapeutic applications of carbon monoxide in lung disease.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Apoptosis; Asthma; Bleomycin; Carbon | 2006 |
Role of carbon monoxide and biliverdin in renal ischemia/reperfusion injury.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Heme Oxygenase (Decyclizing); Humans; Kidney; Repe | 2006 |
Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease.
Topics: Animals; Bilirubin; Carbon Monoxide; Humans; Lung Diseases; Oxidative Stress; Reperfusion Injury; Va | 2007 |
Mechanisms of cell death in oxidative stress.
Topics: Animals; Apoptosis; Carbon Monoxide; Cell Death; Heme Oxygenase-1; Humans; Models, Biological; Oxida | 2007 |
Cytoprotective and anti-inflammatory actions of carbon monoxide in organ injury and sepsis models.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Humans; Lung Diseases; Oxidative Stress; Reperfu | 2007 |
Carbon monoxide: medicinal chemistry and biological effects.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Graft Rejection; Graft Survival; Heart Transplan | 2007 |
New insights into the regulation of hepatic blood flow after ischemia and reperfusion.
Topics: Animals; Carbon Monoxide; Endothelins; Humans; Ischemia; Liver Circulation; Muscle, Smooth, Vascular | 2002 |
103 other studies available for carbon monoxide and Reperfusion Injury
| Article | Year |
|---|---|
Luminal Administration of a Water-soluble Carbon Monoxide-releasing Molecule (CORM-3) Mitigates Ischemia/Reperfusion Injury in Rats Following Intestinal Transplantation.
Topics: Adenosine; Allopurinol; Animals; Carbon Monoxide; Glutathione; Humans; Insulin; Ischemia; Organ Pres | 2022 |
A bioinspired carbon monoxide delivery system prevents acute kidney injury and the progression to chronic kidney disease.
Topics: Acute Kidney Injury; Animals; Carbon Monoxide; Hypoxia; Kidney; Mice; Renal Insufficiency, Chronic; | 2022 |
Deep-Depth Imaging of Hepatic Ischemia/Reperfusion Injury Using a Carbon Monoxide-Activated Upconversion Luminescence Nanosystem.
Topics: Animals; Carbon Monoxide; Luminescence; Mice; Nanoparticles; Reperfusion Injury; Spectroscopy, Near- | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock.
Topics: Animals; Carbon Monoxide; Cytokines; Inflammation; Interferon-gamma; Interleukin-17; Rats; Reperfusi | 2022 |
SANGUINATE (PEGylated Carboxyhemoglobin Bovine): Mechanism of Action and Clinical Update.
Topics: Anemia; Anemia, Sickle Cell; Animals; Blood Substitutes; Brain Ischemia; Carbon Monoxide; Carboxyhem | 2017 |
Exhaled carbon monoxide is correlated with ischemia reperfusion injuries during ex vivo lung perfusion in pigs.
Topics: Animals; Breath Tests; Capillary Permeability; Carbon Monoxide; Exhalation; Lung; Lung Transplantati | 2017 |
The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats' retinal ganglion cells after ischemia and reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Coordination Complexes; Female; Ischemia; Male; | 2017 |
Neuroprotection and neuroregeneration of retinal ganglion cells after intravitreal carbon monoxide release.
Topics: Animals; Axons; Calcium-Binding Proteins; Carbon Monoxide; Caspase 3; Cell Movement; Cells, Cultured | 2017 |
Carbon monoxide protects the kidney through the central circadian clock and CD39.
Topics: Animals; Antigens, CD; Apyrase; Carbon Monoxide; Disease Models, Animal; Humans; Kidney; Kidney Dise | 2018 |
CORM-401 Reduces Ischemia Reperfusion Injury in an Ex Vivo Renal Porcine Model of the Donation After Circulatory Death.
Topics: Adenosine; Allografts; Allopurinol; Animals; Carbon Monoxide; Cold Ischemia; Glutathione; Insulin; K | 2018 |
The Protective Effects of Carbon Monoxide Against Hepatic Warm Ischemia-Reperfusion Injury in MHC-Inbred Miniature Swine.
Topics: Animals; Carbon Monoxide; HMGB1 Protein; Liver; Reperfusion Injury; Swine; Swine, Miniature | 2020 |
Carbon monoxide-releasing molecule-3 protects against cortical pyroptosis induced by hemorrhagic shock and resuscitation via mitochondrial regulation.
Topics: Animals; Carbon Monoxide; Cyclic GMP; Disease Models, Animal; Humans; Mitochondria; Neurons; Neuropr | 2019 |
Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway.
Topics: Animals; Apoptosis; Brain Ischemia; Carbon Monoxide; Cell Line, Tumor; Coordination Complexes; Cycli | 2013 |
5-Aminolevulinic acid combined with ferrous iron induces carbon monoxide generation in mouse kidneys and protects from renal ischemia-reperfusion injury.
Topics: Acute Kidney Injury; Aminolevulinic Acid; Animals; Carbon Monoxide; Cell Death; Drug Evaluation, Pre | 2013 |
Activation of K(2)P channel-TREK1 mediates the neuroprotection induced by sevoflurane preconditioning.
Topics: Animals; Brain; Brain Ischemia; Carbon Monoxide; Cell Differentiation; Cell Hypoxia; Cell Survival; | 2014 |
Carbon monoxide releasing molecule‑2 attenuated ischemia/reperfusion‑induced apoptosis in cardiomyocytes via a mitochondrial pathway.
Topics: Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Carbon M | 2014 |
Carbon monoxide protects against hepatic ischemia/reperfusion injury via ROS-dependent Akt signaling and inhibition of glycogen synthase kinase 3β.
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Cyclic AMP Response Element-Binding Protein; E | 2013 |
Carbon monoxide potently prevents ischemia-induced high-mobility group box 1 translocation and release and protects against lethal renal ischemia-reperfusion injury.
Topics: Active Transport, Cell Nucleus; Animals; Carbon Monoxide; Cell Nucleus; Cells, Cultured; Chemokine C | 2014 |
Real-time measurements of endogenous carbon monoxide production in isolated pig lungs.
Topics: Animals; Carbon Monoxide; Heme Oxygenase-1; Lasers; Lung; Lung Injury; Monitoring, Physiologic; Repe | 2014 |
Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dapsone; Disease Models, Animal; Erythrocy | 2014 |
Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine.
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Microdialysis; Mitochondria; Nitrites; Oxygen | 2015 |
Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway.
Topics: Animals; Carbon Monoxide; Cell Line; Cells, Cultured; Interleukin-1beta; Interleukin-6; Liver; Male; | 2015 |
Inflation with carbon monoxide in rat donor lung during cold ischemia phase ameliorates graft injury.
Topics: Animals; Blood Gas Analysis; Carbon Monoxide; Cold Ischemia; Lung; Male; Oxygen; Rats, Sprague-Dawle | 2016 |
Protective Effect of Antiapoptosis Potency of Prolonged Preservation by Desiccation Using High-Pressure Carbon Monoxide on Isolated Rabbit Hearts.
Topics: Animals; Apoptosis; Carbon Monoxide; Cardioplegic Solutions; Caspase 3; Cryopreservation; Desiccatio | 2015 |
[THE INFLUENCE OF CARBON MONOXIDE ON THE PARAMETERS OF PROOXIDANT-ANTIOXIDANT BALANCE DURING HEPATIC ISCHEMIA-REPERFUSION SYNDROME IN RATS].
Topics: alpha-Tocopherol; Animals; Carbon Monoxide; Catalase; Glutathione; Lipid Peroxidation; Liver; Male; | 2015 |
Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats.
Topics: Animals; Apoptosis; Blood Gas Analysis; Carbon Monoxide; Cold Ischemia; Drug Synergism; Hydrogen; In | 2016 |
Possible role of antioxidants and nitric oxide inhibitors against carbon monoxide poisoning: Having a clear conscience because of their potential benefits.
Topics: Animals; Antioxidants; Brain; Carbon Monoxide; Carbon Monoxide Poisoning; Central Nervous System; Hu | 2016 |
Carbon monoxide treatment reduces microglial activation in the ischemic rat retina.
Topics: Animals; Blood Cells; Calcium-Binding Proteins; Carbon Monoxide; Disease Models, Animal; Female; Flu | 2016 |
Carbon monoxide ameliorates hepatic ischemia/reperfusion injury via sirtuin 1-mediated deacetylation of high-mobility group box 1 in rats.
Topics: Acetylation; Animals; Carbazoles; Carbon Monoxide; HMGB1 Protein; Inflammation; Liver; Liver Transpl | 2017 |
Carbon monoxide ameliorates renal cold ischemia-reperfusion injury with an upregulation of vascular endothelial growth factor by activation of hypoxia-inducible factor.
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Cold Ischemia; Dose-Response Relationship, Dru | 2008 |
Application of nitric oxide and carbon monoxide in a model of renal preservation.
Topics: Animals; Carbon Monoxide; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Organometallic Compounds | 2008 |
Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts.
Topics: Animals; Carbon Monoxide; Cryopreservation; Cytochrome P-450 Enzyme System; Heme; Inflammation Media | 2008 |
Preservation of the kidney by carbon monoxide: a black swan phenomenon.
Topics: Carbon Monoxide; Cytochrome P-450 Enzyme System; Humans; Kidney Transplantation; Organ Preservation; | 2008 |
Carbon monoxide-saturated preservation solution protects lung grafts from ischemia-reperfusion injury.
Topics: Analysis of Variance; Animals; Carbon Monoxide; Disease Models, Animal; Graft Rejection; Graft Survi | 2008 |
Inhibition of Kupffer cell-mediated early proinflammatory response with carbon monoxide in transplant-induced hepatic ischemia/reperfusion injury in rats.
Topics: Animals; Animals, Genetically Modified; Carbon Monoxide; Flow Cytometry; Genes, Reporter; Green Fluo | 2008 |
Low-dose inhaled carbon monoxide attenuates the remote intestinal inflammatory response elicited by hindlimb ischemia-reperfusion.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Carbon Monoxide; Cytokines; Disease M | 2009 |
Low doses of carbon monoxide protect against experimental focal brain ischemia.
Topics: Analysis of Variance; Animals; Brain Edema; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Anim | 2009 |
Role of heme oxygenase-1/carbon monoxide system in pulmonary ischemia-reperfusion injury.
Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Enzyme Inhibitors; Female; Heme | 2009 |
Liver graft exposure to carbon monoxide during cold storage protects sinusoidal endothelial cells and ameliorates reperfusion injury in rats.
Topics: Adenosine; Allopurinol; Animals; Carbon Monoxide; Cryopreservation; Cryoprotective Agents; Endotheli | 2009 |
Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine.
Topics: Animals; Carbon Monoxide; Female; Lung; Male; Reperfusion Injury; Swine; Swine, Miniature | 2010 |
Brief exposure to carbon monoxide preconditions cardiomyogenic cells against apoptosis in ischemia-reperfusion.
Topics: Apoptosis; Carbon Monoxide; Cell Line; Cytoprotection; Humans; Ischemic Preconditioning, Myocardial; | 2010 |
Preconditioning with inhalative carbon monoxide protects rat retinal ganglion cells from ischemia/reperfusion injury.
Topics: Administration, Inhalation; Animals; Blotting, Western; Carbon Monoxide; Caspase 3; Cell Count; Cell | 2010 |
Ex vivo application of carbon monoxide in UW solution prevents transplant-induced renal ischemia/reperfusion injury in pigs.
Topics: Animals; Blotting, Western; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Graft Surviv | 2010 |
[Carbon monoxide inhalation protects against limb ischemia/reperfusion injury].
Topics: Administration, Inhalation; Animals; bcl-2-Associated X Protein; Carbon Monoxide; Creatine Kinase; E | 2010 |
Protection of carbon monoxide intraperitoneal administration from rat intestine injury induced by lipopolysaccharide.
Topics: Aldehydes; Animals; Blotting, Western; Carbon Monoxide; Flow Cytometry; Intercellular Adhesion Molec | 2010 |
CO releasing properties and cytoprotective effect of cis-trans-[Re(II)(CO)2Br2L2]n complexes.
Topics: Animals; Carbon Monoxide; Cytoprotection; Myocytes, Cardiac; Organometallic Compounds; Rats; Rats, W | 2010 |
No synergistic effect of carbon monoxide and oxygen during static gaseous persufflation preservation of DCD livers.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Alanine Transaminase; Animal | 2011 |
Intraoperative administration of inhaled carbon monoxide reduces delayed graft function in kidney allografts in Swine.
Topics: Animals; Carbon Monoxide; Cell Death; Cell Proliferation; Delayed Graft Function; Female; Gene Expre | 2010 |
Carbon monoxide has antioxidative properties in the liver involving p38 MAP kinase pathway in a murine model of systemic inflammation.
Topics: Animals; Antioxidants; Bilirubin; Carbon Monoxide; Carboxyhemoglobin; Cells, Cultured; Disease Model | 2010 |
[Exogenous carbon monoxide protects against liver injury induced by ischemia/reperfusion of hind limbs in rats].
Topics: Animals; Carbon Monoxide; Extremities; Female; Liver; Liver Diseases; Male; Rats; Rats, Sprague-Dawl | 2009 |
Heme oxygenase system in hepatic ischemia-reperfusion injury.
Topics: Adaptive Immunity; Animals; Antioxidants; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decycl | 2010 |
Protection against lung graft injury from brain-dead donors with carbon monoxide, biliverdin, or both.
Topics: Animals; Antioxidants; Biliverdine; Brain Death; Carbon Monoxide; Male; Rats; Rats, Wistar; Reperfus | 2011 |
[Effects of carbon monoxide inhalation on severe limb ischemia/reperfusion injury and its damages lead to shock].
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Creatine Kinase; Extremities; L-Lactate Dehydr | 2011 |
Carbon monoxide induces hypothermia tolerance in Kupffer cells and attenuates liver ischemia/reperfusion injury in rats.
Topics: Administration, Inhalation; Animals; Apoptosis; bcl-2-Associated X Protein; Carbon Monoxide; Caspase | 2011 |
Emerging roles for gasotransmitters.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Humans; Hydrogen Sulfide; I | 2011 |
17 e- rhenium dicarbonyl CO-releasing molecules on a cobalamin scaffold for biological application.
Topics: Animals; Animals, Newborn; Carbon Monoxide; Cell Survival; Cells, Cultured; Cytoprotection; Drug Des | 2012 |
Therapeutic potential of pegylated hemin for reactive oxygen species-related diseases via induction of heme oxygenase-1: results from a rat hepatic ischemia/reperfusion injury model.
Topics: Animals; Apoptosis; Carbon Monoxide; Cardiotonic Agents; Caspase 3; Caspase 7; Cell Survival; Chemok | 2011 |
Carbon monoxide inhibits apoptosis during cold storage and protects kidney grafts donated after cardiac death.
Topics: Adenosine; Allopurinol; Animals; Apoptosis; Carbon Monoxide; Cold Temperature; Cytosol; Death; Gluta | 2012 |
Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation.
Topics: Adolescent; Adult; Animals; Carbon Monoxide; Exhalation; Female; Heme; Heme Oxygenase-1; Humans; Liv | 2012 |
Carbon monoxide modulates apoptosis by reinforcing oxidative metabolism in astrocytes: role of Bcl-2.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Astrocytes; Carbon Monoxide; Cell Hypoxia; Cytoprotectio | 2012 |
Inhalation of carbon monoxide reduces skeletal muscle injury after hind limb ischemia-reperfusion injury in mice.
Topics: Adenosine Triphosphate; Administration, Inhalation; Analysis of Variance; Animals; Blood Gas Analysi | 2012 |
Carbon monoxide protects against ischemia-reperfusion injury in vitro via antioxidant properties.
Topics: Animals; Antioxidants; Carbon Monoxide; Cardiotonic Agents; Ethidium; Heart; In Vitro Techniques; L- | 2012 |
Postconditioning with inhaled carbon monoxide counteracts apoptosis and neuroinflammation in the ischemic rat retina.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Apoptosis; bcl-2-Associated X Protein | 2012 |
Increased carboxyhemoglobin level during liver resection with inflow occlusion.
Topics: Alanine Transaminase; Anesthesia; Aspartate Aminotransferases; Blood Loss, Surgical; Blood Transfusi | 2013 |
Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors.
Topics: Animals; Blotting, Western; Carbon Monoxide; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Extracel | 2013 |
[Effect of endogenous carbon monoxide on oxidant-mediated multiple organ injury following limb ischemia-reperfusion in rats].
Topics: Animals; Carbon Monoxide; Extremities; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2002 |
The role of heme oxygenase-related carbon monoxide and ventricular fibrillation in ischemic/reperfused hearts.
Topics: Animals; Blotting, Northern; Blotting, Western; Carbon Monoxide; Chromatography, Gas; Free Radicals; | 2002 |
Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.
Topics: Animals; Apoptosis; Carbon Monoxide; Caspase 3; Caspases; Cells, Cultured; Guanylate Cyclase; Heme O | 2003 |
Carbon monoxide modulates Fas/Fas ligand, caspases, and Bcl-2 family proteins via the p38alpha mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury.
Topics: Animals; Apoptosis; Carbon Monoxide; Caspase 3; Caspase 8; Caspase 9; Caspases; Cytochrome c Group; | 2003 |
Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule.
Topics: Animals; Carbon Monoxide; Cardiotonic Agents; Cells, Cultured; Decanoic Acids; Disease Models, Anima | 2003 |
Bilirubin rinse: A simple protectant against the rat liver graft injury mimicking heme oxygenase-1 preconditioning.
Topics: Adenosine; Allopurinol; Animals; Bile; Bilirubin; Carbon Monoxide; Cholestasis, Intrahepatic; Glutat | 2003 |
Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts.
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Carboxyhemoglobin; Cryopreservation; Enzyme In | 2003 |
Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury.
Topics: Administration, Inhalation; Animals; Blood Vessels; Carbon Monoxide; Carboxyhemoglobin; Corrosion Ca | 2003 |
Exhaled carbon monoxide and inducible heme oxygenase expression in a rat model of postperfusion acute lung injury.
Topics: Acute Disease; Animals; Blotting, Western; Breath Tests; Carbon Monoxide; Extracorporeal Circulation | 2003 |
Protection of transplant-induced renal ischemia-reperfusion injury with carbon monoxide.
Topics: Actins; Administration, Inhalation; Animals; Apoptosis; Blotting, Western; Carbon Monoxide; Carboxyh | 2004 |
Carbon monoxide protects against cardiac ischemia--reperfusion injury in vivo via MAPK and Akt--eNOS pathways.
Topics: Animals; Carbon Monoxide; Cyclic GMP; Hemoglobins; Inhalation; Mitogen-Activated Protein Kinases; My | 2004 |
Heme oxygenase-1-related carbon monoxide and flavonoids in ischemic/reperfused rat retina.
Topics: Animals; Blotting, Western; Calcium; Carbon Monoxide; Chromatography, Gas; Flavonoids; Heme Oxygenas | 2004 |
Inhalation of carbon monoxide prevents liver injury and inflammation following hind limb ischemia/reperfusion.
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Enzyme Induction; Heme Oxygenase (Decyclizing) | 2005 |
Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both.
Topics: Animals; Biliverdine; Carbon Monoxide; Cell Movement; Heart Transplantation; Heme Oxygenase (Decycli | 2005 |
Low-dose carbon monoxide inhalation prevents development of chronic allograft nephropathy.
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Cell Adhesion Molecules; Cytokines; Fibrosis; | 2006 |
Carbon monoxide inhalation ameliorates cold ischemia/reperfusion injury after rat liver transplantation.
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Cryopreservation; Gene Expression; Hemoglobins | 2005 |
Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury.
Topics: Animals; Carbon Monoxide; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Electron Transport | 2006 |
[Effect of exogenous carbon monoxide on sequestration of polymorphonuclear neutrophils in the lung following limb ischemia-reperfusion: an experimental study].
Topics: Animals; Capillaries; Carbon Monoxide; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans | 2005 |
Treatment with CO-RMs during cold storage improves renal function at reperfusion.
Topics: Animals; Carbon Monoxide; Cold Temperature; Kidney; Male; Mitochondria; Organ Preservation; Oxadiazo | 2006 |
Carbon monoxide: from silent killer to potential remedy.
Topics: Animals; Antineoplastic Agents; Carbon Monoxide; Cisplatin; Cyclic GMP; Heme Oxygenase-1; Kidney Dis | 2006 |
Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure.
Topics: Acute Kidney Injury; Animals; Apoptosis; Carbon Monoxide; Cell Line; Creatinine; Gene Expression Reg | 2006 |
Ex vivo application of carbon monoxide in University of Wisconsin solution to prevent intestinal cold ischemia/reperfusion injury.
Topics: Adenosine; Allopurinol; Animals; Antimetabolites; Carbon Monoxide; Disease Models, Animal; Glutathio | 2006 |
Low-dose carbon monoxide inhalation prevents ischemia/reperfusion injury of transplanted rat lung grafts.
Topics: Administration, Inhalation; Animals; Blood Gas Analysis; Carbon Monoxide; Drug Administration Schedu | 2006 |
Carbon monoxide inhibits hypoxia/reoxygenation-induced apoptosis and secondary necrosis in syncytiotrophoblast.
Topics: Apoptosis; Carbon Monoxide; Cell Differentiation; Cell Hypoxia; Cells, Cultured; Female; Humans; Nec | 2006 |
[Effects of carbon monoxide on polymorphonuclear leukocyte apoptosis stimulated by limb ischemia-reperfusion patient serum and the role of nuclear factor-kappaB].
Topics: Aged; Apoptosis; Carbon Monoxide; Cells, Cultured; Culture Media; Electrophoretic Mobility Shift Ass | 2006 |
Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning.
Topics: Animals; Apoptosis; Carbon Monoxide; Cell Hypoxia; Cell Survival; Cytoprotection; Gene Expression Re | 2007 |
Carbon monoxide protects rat lung transplants from ischemia-reperfusion injury via a mechanism involving p38 MAPK pathway.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Cyclooxygenase 2; Interleukins; Lung; Lung Trans | 2007 |
Carbon monoxide can prevent acute lung injury observed after ischemia reperfusion of the lower extremities.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Bilirubin; Blood Pressure; Carbon Monoxide; Colo | 2007 |
Heme oxygenase-1 ameliorates ischemia/reperfusion injury by targeting dendritic cell maturation and migration.
Topics: Animals; Biomarkers; Carbon Monoxide; Cell Movement; Cells, Cultured; Cold Temperature; Dendritic Ce | 2007 |
Protection of transplant-induced hepatic ischemia/reperfusion injury with carbon monoxide via MEK/ERK1/2 pathway downregulation.
Topics: Administration, Inhalation; Alanine Transaminase; Animals; Apoptosis Regulatory Proteins; Carbon Mon | 2008 |
Improved myocardial function after cold storage with preservation solution supplemented with a carbon monoxide-releasing molecule (CORM-3).
Topics: Animals; Carbon Monoxide; Cold Ischemia; Creatine Kinase; Cryopreservation; Graft Rejection; Heart; | 2007 |
Anesthetics and natural heme oxygenase-1 inducers: waiting for carbon monoxide?
Topics: Anesthetics; Animals; Anthocyanins; Antioxidants; Carbon Monoxide; Curcumin; Cytoprotection; Disease | 2008 |
Inhaled CO: deadly gas or novel therapeutic?
Topics: Administration, Inhalation; Animals; Carbon Monoxide; Lung; Mice; Reperfusion Injury | 2001 |
Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis.
Topics: Animals; Base Sequence; Carbon Monoxide; Cell Line; DNA Primers; Female; Fibrinolysis; Heme Oxygenas | 2001 |
The heme oxygenase-1 pathway is involved in calcitonin gene-related peptide-mediated delayed cardioprotection induced by monophosphoryl lipid A in rats.
Topics: Adjuvants, Immunologic; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carbon Monoxide; Cardio | 2002 |
Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway.
Topics: Animals; Carbon Monoxide; Cold Temperature; Cyclic GMP; Enzyme Activation; Heme Oxygenase (Decyclizi | 2002 |
Endogenous carbon monoxide attenuates lung injury following ischemia-reperfusion in the hind limbs of rats.
Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Heme Oxygenase (Decyclizing); Hindlimb; Lung Diseases; | 2002 |
Physiological targets of superoxide anion and hydrogen peroxide in reperfusion injury.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Carbon Monoxide; Centrifugation; Chromatograph | 1989 |