Page last updated: 2024-10-16

carbon monoxide and Osteoarthritis

carbon monoxide has been researched along with Osteoarthritis in 4 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
"We have investigated the effects of a carbon monoxide-releasing molecule, tricarbonyldichlororuthenium(II) dimer (CORM-2), on catabolic processes in human osteoarthritis (OA) cartilage and chondrocytes activated with interleukin-1beta."3.74The carbon monoxide-releasing molecule tricarbonyldichlororuthenium(II) dimer protects human osteoarthritic chondrocytes and cartilage from the catabolic actions of interleukin-1beta. ( Alcaraz, MJ; Bru, A; Gomar, F; Guillén, MI; Megías, J, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rousset, F1
Nguyen, MV1
Grange, L1
Morel, F1
Lardy, B1
Mitlyng, BL1
Singh, JA1
Furne, JK1
Ruddy, J1
Levitt, MD1
Megías, J2
Guillén, MI2
Bru, A1
Gomar, F1
Alcaraz, MJ2
Ferrandiz, ML1
Motterlini, R1

Trials

1 trial available for carbon monoxide and Osteoarthritis

ArticleYear
Use of breath carbon monoxide measurements to assess erythrocyte survival in subjects with chronic diseases.
    American journal of hematology, 2006, Volume: 81, Issue:6

    Topics: Aged; Aged, 80 and over; Anemia; Arthritis, Rheumatoid; Bone Marrow; Breath Tests; Carbon Monoxide;

2006

Other Studies

3 other studies available for carbon monoxide and Osteoarthritis

ArticleYear
Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Apoptosis; Carbon Monoxide; Chondrocytes; DNA Fragmentation; Green Fluorescent Proteins; HEK293 Cell

2013
The carbon monoxide-releasing molecule tricarbonyldichlororuthenium(II) dimer protects human osteoarthritic chondrocytes and cartilage from the catabolic actions of interleukin-1beta.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:1

    Topics: Aged; Aggrecans; Carbon Monoxide; Cartilage; Chondrocytes; Collagen Type II; Down-Regulation; Female

2008
Carbon monoxide-releasing molecules: a pharmacological expedient to counteract inflammation.
    Current pharmaceutical design, 2008, Volume: 14, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbon Monoxide; Cytokines; Heme Oxygenase

2008