Page last updated: 2024-10-16

carbon monoxide and Neurodegenerative Diseases

carbon monoxide has been researched along with Neurodegenerative Diseases in 14 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen sulfide (H2S)has emerged as pivotal signaling molecules since it is recognized as the third gasotransmitter together with nitric oxide and carbon monoxide."2.55[The Molecular Switches and Atomic Biological Mechanisms Underlying the Physiological and Pathophysio-logical Effects of Hydrogen Sulfide to Regulate Its "Receptors"]. ( Cai, WJ; Li, XH; Tao, BB; Wang, MJ; Xue, WL; Zhu, YC, 2017)
" It is argued that the hormetic dose response provides the central underpinning of neuroprotective responses, providing a framework for explaining the common quantitative features of their dose-response relationships, their mechanistic foundations, and their relationship to the concept of biological plasticity, as well as providing a key insight for improving the accuracy of the therapeutic dose of pharmaceutical agents within the highly heterogeneous human population."2.46Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. ( Calabrese, EJ; Calabrese, V; Cornelius, C; Dinkova-Kostova, AT; Mattson, MP, 2010)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's6 (42.86)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Gottfried, I1
Schottlender, N1
Ashery, U1
Parks, RM1
Nunez, Y1
Balalian, AA1
Gibson, EA1
Hansen, J1
Raaschou-Nielsen, O1
Ketzel, M1
Khan, J1
Brandt, J1
Vermeulen, R1
Peters, S1
Goldsmith, J1
Re, DB1
Weisskopf, MG1
Kioumourtzoglou, MA1
Rodkin, S1
Nwosu, C1
Sannikov, A1
Tyurin, A1
Chulkov, VS1
Raevskaya, M1
Ermakov, A1
Kirichenko, E1
Gasanov, M1
Xue, WL1
Cai, WJ1
Tao, BB1
Wang, MJ1
Li, XH1
Zhu, YC1
Lee, H1
Choi, YK1
Peers, C1
Boyle, JP1
Smolle-Jüttner, FM1
Calabrese, V3
Cornelius, C2
Mancuso, C1
Lentile, R1
Stella, AM2
Butterfield, DA2
Dinkova-Kostova, AT1
Calabrese, EJ1
Mattson, MP1
Bishop, A1
Cashman, NR1
Takeda, A1
Itoyama, Y1
Kimpara, T1
Zhu, X1
Avila, J1
Dwyer, BE1
Perry, G1
Smith, MA1
Scapagnini, G1
Cuadrado, A1
Rojo, AI1
Sharma, HS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cognitive Improvement After cARotid stEnting in HyperBaric Oxygen Therapy Trial (CARE-HBOT)[NCT05980195]90 participants (Anticipated)Interventional2023-08-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for carbon monoxide and Neurodegenerative Diseases

ArticleYear
Hyperbaric Oxygen Treatment-From Mechanisms to Cognitive Improvement.
    Biomolecules, 2021, 10-15, Volume: 11, Issue:10

    Topics: Aged; Brain; Carbon Monoxide; Cognition; Humans; Hyperbaric Oxygenation; Inflammation; Mitochondria;

2021
The Role of Gasotransmitter-Dependent Signaling Mechanisms in Apoptotic Cell Death in Cardiovascular, Rheumatic, Kidney, and Neurodegenerative Diseases and Mental Disorders.
    International journal of molecular sciences, 2023, Mar-23, Volume: 24, Issue:7

    Topics: Apoptosis; Carbon Monoxide; Gasotransmitters; Humans; Hydrogen Sulfide; Kidney; Mental Disorders; Ne

2023
[The Molecular Switches and Atomic Biological Mechanisms Underlying the Physiological and Pathophysio-logical Effects of Hydrogen Sulfide to Regulate Its "Receptors"].
    Sheng li ke xue jin zhan [Progress in physiology], 2017, Volume: 48, Issue:1

    Topics: Asthma; Atherosclerosis; Carbon Monoxide; Cardiovascular System; Humans; Hydrogen Sulfide; Hypertens

2017
Regenerative Effects of Heme Oxygenase Metabolites on Neuroinflammatory Diseases.
    International journal of molecular sciences, 2018, Dec-25, Volume: 20, Issue:1

    Topics: Bilirubin; Brain-Derived Neurotrophic Factor; Carbon Monoxide; Heme Oxygenase (Decyclizing); Humans;

2018
Oxidative modulation of K+ channels in the central nervous system in neurodegenerative diseases and aging.
    Antioxidants & redox signaling, 2015, Feb-20, Volume: 22, Issue:6

    Topics: Aging; Animals; Apoptosis; Carbon Monoxide; Central Nervous System; Gasotransmitters; Humans; Hydrog

2015
Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders.
    Antioxidants & redox signaling, 2010, Dec-01, Volume: 13, Issue:11

    Topics: Animals; Carbon Monoxide; Cell Membrane; Dose-Response Relationship, Drug; Heme Oxygenase (Decyclizi

2010
Induced adaptive resistance to oxidative stress in the CNS: a discussion on possible mechanisms and their therapeutic potential.
    Current drug metabolism, 2003, Volume: 4, Issue:2

    Topics: Adaptation, Physiological; Carbon Monoxide; Central Nervous System; Drug Resistance; Free Radicals;

2003
Heme catabolism and heme oxygenase in neurodegenerative disease.
    Antioxidants & redox signaling, 2004, Volume: 6, Issue:5

    Topics: Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Iron; Isoenzymes; Molecular Structure;

2004
Redox regulation in neurodegeneration and longevity: role of the heme oxygenase and HSP70 systems in brain stress tolerance.
    Antioxidants & redox signaling, 2004, Volume: 6, Issue:5

    Topics: Aging; Antioxidants; Brain; Carbon Monoxide; Gene Expression Regulation, Enzymologic; Heme Oxygenase

2004
Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections.
    Current pharmaceutical design, 2008, Volume: 14, Issue:5

    Topics: Alzheimer Disease; Animals; Biliverdine; Brain; Carbon Monoxide; Central Nervous System Infections;

2008

Other Studies

4 other studies available for carbon monoxide and Neurodegenerative Diseases

ArticleYear
Long-term Traffic-related Air Pollutant Exposure and Amyotrophic Lateral Sclerosis Diagnosis in Denmark: A Bayesian Hierarchical Analysis.
    Epidemiology (Cambridge, Mass.), 2022, 11-01, Volume: 33, Issue:6

    Topics: Air Pollutants; Air Pollution; Amyotrophic Lateral Sclerosis; Bayes Theorem; Carbon Monoxide; Case-C

2022
[CO intoxication: what to do after the acute episode?].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:50

    Topics: Brain; Brain Damage, Chronic; Carbon Monoxide; Carbon Monoxide Poisoning; Cardiomyopathies; Dementia

2014
Redox homeostasis and cellular stress response in aging and neurodegeneration.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 610

    Topics: Acetylcarnitine; Aging; Animals; Carbon Monoxide; Gene Regulatory Networks; Heme Oxygenase-1; Homeos

2010
Neurodegeneration and regeneration in the CNS. New roles of heat shock proteins, nitric oxide and carbon monoxide.
    Amino acids, 2000, Volume: 19, Issue:1

    Topics: Carbon Monoxide; Central Nervous System; Heat-Shock Proteins; Humans; Neurodegenerative Diseases; Ni

2000