Page last updated: 2024-10-16

carbon monoxide and Nerve Pain

carbon monoxide has been researched along with Nerve Pain in 6 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Research Excerpts

ExcerptRelevanceReference
"Neuropathic pain is a devastating chronic condition and effective treatments are still lacking."1.51Nanocarrier-mediated Delivery of CORM-2 Enhances Anti-allodynic and Anti-hyperalgesic Effects of CORM-2. ( Choi, H; Han, IB; Jo, MJ; Joshi, HP; Kim, J; Kim, JK; Kim, KT; Kim, S; Kim, SB; Kumar, H; Kyung, JW; Sohn, S, 2019)
"In male C57BL6 mice with neuropathic pain induced by the chronic constriction of sciatic nerve (CCI), we evaluated the effects of CORM-2 and CoPP on the expression of the nuclear factor erythroid 2-related factor 2 (Nrf2), HO-1 and NAD(P)H:quinone oxidoreductase-1 (NQO1), the microglial marker (CD11b/c), and the mitogen-activated protein kinases (MAPK) (JNK, ERK½ and P38) in the amygdala, prefrontal cortex, hippocampus, hypothalamus and spinal cord, by using western blot assay."1.48Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain. ( Leánez, S; Pol, O; Redondo, A; Riego, G, 2018)
"Hydrogen (H2) has anti-inflammation, anti-apoptosis, and anti-oxidative stress effects."1.42H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. ( Chen, H; Chen, Y; Li, Y; Liu, L; Wang, G; Xie, K; Yu, Y, 2015)
"In WT mice, the main neuropathic pain symptoms induced by nerve injury were significantly reduced in a time-dependent manner by treatment with CO-RMs or CoPP."1.38Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice. ( Hervera, A; Leánez, S; Motterlini, R; Negrete, R; Pol, O, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Riego, G1
Redondo, A1
Leánez, S3
Pol, O3
Joshi, HP1
Kim, SB1
Kim, S1
Kumar, H1
Jo, MJ1
Choi, H1
Kim, J1
Kyung, JW1
Sohn, S1
Kim, KT1
Kim, JK1
Han, IB1
Chen, Y1
Chen, H1
Xie, K1
Liu, L1
Li, Y1
Yu, Y1
Wang, G1
Schmidtko, A1
Gao, W1
König, P1
Heine, S1
Motterlini, R3
Ruth, P1
Schlossmann, J1
Koesling, D1
Niederberger, E1
Tegeder, I1
Friebe, A1
Geisslinger, G1
Hervera, A2
Negrete, R1

Other Studies

6 other studies available for carbon monoxide and Nerve Pain

ArticleYear
Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain.
    Biochemical pharmacology, 2018, Volume: 148

    Topics: Animals; Carbon Monoxide; Central Nervous System; Gene Expression Regulation; Heme Oxygenase-1; Hype

2018
Nanocarrier-mediated Delivery of CORM-2 Enhances Anti-allodynic and Anti-hyperalgesic Effects of CORM-2.
    Molecular neurobiology, 2019, Volume: 56, Issue:8

    Topics: Animals; Calcium-Binding Proteins; Carbon Monoxide; Drug Carriers; Female; Ganglia, Spinal; Gene Exp

2019
H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.
    Inflammation, 2015, Volume: 38, Issue:5

    Topics: Animals; Carbon Monoxide; Cytokines; Disease Models, Animal; Heme Oxygenase-1; Hydrogen; Male; Neura

2015
cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Aug-20, Volume: 28, Issue:34

    Topics: Animals; Behavior, Animal; Carbon Monoxide; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I;

2008
Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Carbon Monoxide; CD11b Antigen; CD11c Antigen; Enzyme Induction; Ganglia, Spinal; Gene Expr

2012
Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of µ-opioid receptors during neuropathic pain.
    Anesthesiology, 2013, Volume: 118, Issue:5

    Topics: Analgesics, Opioid; Animals; Carbon Monoxide; Constriction, Pathologic; Enkephalin, D-Penicillamine

2013