Page last updated: 2024-10-16

carbon monoxide and Neoplasm Metastasis

carbon monoxide has been researched along with Neoplasm Metastasis in 4 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) induces DNA damage via a chloroethyl adduct at the O(6) position of guanine, which can be repaired by O(6)-alkylguanine DNA alkyltransferase (AGT) expressed in melanoma."9.11Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma. ( Dolan, E; Gajewski, TF; Gerson, SL; Lin, S; Liu, L; Sosman, J; Vokes, EE, 2005)
"1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) induces DNA damage via a chloroethyl adduct at the O(6) position of guanine, which can be repaired by O(6)-alkylguanine DNA alkyltransferase (AGT) expressed in melanoma."5.11Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma. ( Dolan, E; Gajewski, TF; Gerson, SL; Lin, S; Liu, L; Sosman, J; Vokes, EE, 2005)
"In the pulmonary metastasis model, L-NAME increased both the number of tumor cells 24 h later and outcome of metastases 18 days later, but did not have a significant effect on liver metastasis."1.32Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice. ( Handa, O; Higashihara, H; Inoue, M; Ishikawa, T; Kokura, S; Naito, Y; Okanoue, T; Takagi, T; Uchiyama, K; Yoshida, N; Yoshikawa, T, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yin, H1
Fang, J1
Liao, L1
Maeda, H1
Su, Q1
Park, K1
Kim, HJ1
Lee, JL1
Lee, KH1
Jeong, IG1
Song, C1
Hong, BS1
Hong, J1
Kim, CS1
Ahn, H1
Ishikawa, T1
Yoshida, N1
Higashihara, H1
Inoue, M1
Uchiyama, K1
Takagi, T1
Handa, O1
Kokura, S1
Naito, Y1
Okanoue, T1
Yoshikawa, T1
Gajewski, TF1
Sosman, J1
Gerson, SL1
Liu, L1
Dolan, E1
Lin, S1
Vokes, EE1

Trials

1 trial available for carbon monoxide and Neoplasm Metastasis

ArticleYear
Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Nov-01, Volume: 11, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineopla

2005

Other Studies

3 other studies available for carbon monoxide and Neoplasm Metastasis

ArticleYear
Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity.
    BMC cancer, 2014, Jun-14, Volume: 14

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Carbon Monoxide; Cell Line, Tumor; C

2014
Changes in the diffusion capacity for carbon monoxide and the development of non-infectious pneumonitis in patients with metastatic renal cell carcinoma treated with everolimus.
    Anticancer research, 2014, Volume: 34, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carbon Monoxide; Carcinoma, Renal Cell; Evero

2014
Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice.
    Clinical & experimental metastasis, 2003, Volume: 20, Issue:5

    Topics: Animals; Carbon Monoxide; Colonic Neoplasms; Deuteroporphyrins; Heme Oxygenase (Decyclizing); Liver;

2003