carbon monoxide has been researched along with Muscle Relaxation in 44 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbon monoxide (CO), a vasodilator, has been implicated as an activator of soluble guanylyl cyclase (sGC) to effect smooth muscle relaxation; however, this idea has not received universal support." | 3.69 | The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ) inhibits relaxation of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate. ( Brien, JF; Hussain, AS; Marks, GS; Nakatsu, K, 1997) |
| "Carbon monoxide (CO) is an endogenously generated gas that may play an important physiological role in the regulation of vascular tone." | 2.40 | Resurgence of carbon monoxide: an endogenous gaseous vasorelaxing factor. ( Wang, R, 1998) |
| "Hypertension was induced by N-nitro-l-arginine methyl ester (25 mg/kg/day in drinking water), and exercise training comprised swimming 1 h/day, 5 days/week, for 6 weeks." | 1.46 | Carbon monoxide does not contribute to vascular tonus improvement in exercise-trained rats with chronic nitric oxide synthase inhibition. ( Koçer, G; Şentürk, ÜK; Ülker, SN, 2017) |
| "Abdominal pain was increased by an acute gavage of pollution extract but not to chronic exposure to pollutants." | 1.38 | Non-specific abdominal pain and air pollution: a novel association. ( Fichna, J; Ghosh, S; Kaplan, GG; Madsen, K; Porada, E; Rowe, BH; Storr, M; Szyszkowicz, M; Vincent, R, 2012) |
| "Carbon monoxide (CO) has recently emerged as a potent, endogenously produced mediator of bronchodilation." | 1.31 | The induction of carbon monoxide-mediated airway relaxation by PACAP 38 in isolated guinea pig airways. ( Cardell, LO; Kinhult, J; Uddman, R, 2001) |
| "Carbon monoxide has been proposed as a possible neurotransmitter because of its ability to bind to the iron atom of the heme of guanylyl cyclase, which is similar to that of nitric oxide." | 1.29 | Lack of effect of carbon monoxide inhibitor on relaxation induced by electrical field stimulation in corpus cavernosum. ( Carson, CC; Davies, MG; Hagen, PO; Kim, YC; Marson, L, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.55) | 18.7374 |
| 1990's | 15 (34.09) | 18.2507 |
| 2000's | 22 (50.00) | 29.6817 |
| 2010's | 5 (11.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ülker, SN | 1 |
| Koçer, G | 1 |
| Şentürk, ÜK | 1 |
| Leo, MD | 1 |
| Siddegowda, YK | 1 |
| Kumar, D | 1 |
| Tandan, SK | 1 |
| Sastry, KV | 1 |
| Prakash, VR | 1 |
| Mishra, SK | 1 |
| Piepoli, AL | 1 |
| de Salvatore, G | 1 |
| Lemoli, M | 1 |
| de Benedictis, L | 1 |
| Mitolo-Chieppa, D | 1 |
| de Salvia, MA | 1 |
| Dellabianca, A | 2 |
| Faniglione, M | 1 |
| De Angelis, S | 1 |
| Colucci, M | 1 |
| Cervio, M | 1 |
| Balestra, B | 1 |
| Tonini, S | 2 |
| Candura, SM | 2 |
| Hidaka, A | 1 |
| Azuma, YT | 1 |
| Nakajima, H | 1 |
| Takeuchi, T | 1 |
| Decaluwé, K | 1 |
| Pauwels, B | 1 |
| Boydens, C | 1 |
| Van de Voorde, J | 1 |
| Kaplan, GG | 1 |
| Szyszkowicz, M | 1 |
| Fichna, J | 1 |
| Rowe, BH | 1 |
| Porada, E | 1 |
| Vincent, R | 1 |
| Madsen, K | 1 |
| Ghosh, S | 1 |
| Storr, M | 1 |
| Colpaert, EE | 1 |
| Timmermans, JP | 1 |
| Lefebvre, RA | 2 |
| Rattan, S | 5 |
| Al Haj, R | 1 |
| De Godoy, MA | 2 |
| Currò, D | 1 |
| De Marco, T | 1 |
| Preziosi, P | 1 |
| Regan, RF | 1 |
| Patel, CA | 1 |
| Ushiyama, M | 1 |
| Kuramochi, T | 1 |
| Katayama, S | 1 |
| Sacchi, M | 1 |
| Anselmi, L | 1 |
| De Amici, E | 1 |
| Cervio, E | 1 |
| Agazzi, A | 1 |
| Sternini, C | 1 |
| Tonini, M | 1 |
| De Backer, O | 1 |
| Zygmunt, PM | 1 |
| Högestätt, ED | 1 |
| Grundemar, L | 2 |
| Kim, YC | 1 |
| Davies, MG | 1 |
| Marson, L | 1 |
| Hagen, PO | 1 |
| Carson, CC | 1 |
| Chakder, S | 2 |
| Ny, L | 3 |
| Alm, P | 1 |
| Ekström, P | 1 |
| Larsson, B | 1 |
| Andersson, KE | 4 |
| Coceani, F | 3 |
| Kelsey, L | 3 |
| Seidlitz, E | 2 |
| Marks, GS | 3 |
| McLaughlin, BE | 2 |
| Vreman, HJ | 1 |
| Stevenson, DK | 1 |
| Rabinovitch, M | 1 |
| Ackerley, C | 1 |
| Werkström, V | 1 |
| Persson, K | 2 |
| Wang, R | 2 |
| Wang, Z | 1 |
| Wu, L | 1 |
| Hussain, AS | 1 |
| Brien, JF | 2 |
| Nakatsu, K | 2 |
| Waldeck, K | 1 |
| Fan, YP | 1 |
| Saotome, M | 1 |
| Uchida, Y | 1 |
| Nomura, A | 1 |
| Endo, T | 1 |
| Hasegawa, S | 1 |
| Naseem, KM | 1 |
| Mumtaz, FH | 1 |
| Thompson, CS | 1 |
| Sullivan, ME | 1 |
| Khan, MA | 1 |
| Morgan, RJ | 1 |
| Mikhailidis, DP | 1 |
| Bruckdorfer, KR | 1 |
| Xue, L | 1 |
| Farrugia, G | 1 |
| Miller, SM | 2 |
| Ferris, CD | 1 |
| Snyder, SH | 1 |
| Szurszewski, JH | 1 |
| Chretien, ML | 1 |
| Choi, C | 1 |
| Carvajal, JA | 1 |
| Germain, AM | 1 |
| Huidobro-Toro, JP | 1 |
| Weiner, CP | 1 |
| Villamor, E | 1 |
| Pérez-Vizcaíno, F | 1 |
| Cogolludo, AL | 1 |
| Conde-Oviedo, J | 1 |
| Zaragozá-Arnáez, F | 1 |
| López-López, JG | 1 |
| Tamargo, J | 1 |
| Kwon, S | 1 |
| Chung, S | 1 |
| Ahn, D | 1 |
| Yeon, D | 1 |
| Nam, T | 1 |
| Kinhult, J | 1 |
| Uddman, R | 1 |
| Cardell, LO | 1 |
| Mustafa, S | 1 |
| Thulesius, O | 1 |
| Alcón, S | 1 |
| Morales, S | 1 |
| Camello, PJ | 1 |
| Salido, GM | 1 |
| Pozo, MJ | 1 |
| Schroder, A | 1 |
| Hedlund, P | 1 |
| Townsend, CL | 1 |
| Maynard, R | 1 |
| Utz, J | 1 |
| Ullrich, V | 1 |
| Gräser, T | 2 |
| Vedernikov, YP | 2 |
| Li, DS | 1 |
| Vanin, AF | 1 |
| Ignarro, LJ | 1 |
| Byrns, RE | 1 |
| Buga, GM | 1 |
| Wood, KS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease[NCT00095472] | Phase 1 | 18 participants (Actual) | Interventional | 2004-11-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for carbon monoxide and Muscle Relaxation
| Article | Year |
|---|---|
The internal anal sphincter: regulation of smooth muscle tone and relaxation.
Topics: Anal Canal; Angiotensin II; Animals; Carbon Monoxide; Humans; Muscle Relaxation; Muscle Tonus; Muscl | 2005 |
Resurgence of carbon monoxide: an endogenous gaseous vasorelaxing factor.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Guanylate Cyclase; Humans; Muscle Rela | 1998 |
Molecular mechanism of cGMP-mediated smooth muscle relaxation.
Topics: Animals; Calcium; Carbon Monoxide; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Depe | 2000 |
Changing views on carbon monoxide.
Topics: Animals; Carbon Monoxide; Carotid Body; Enzyme Activation; Guanylate Cyclase; Hypothalamus; Intestin | 2002 |
40 other studies available for carbon monoxide and Muscle Relaxation
| Article | Year |
|---|---|
Carbon monoxide does not contribute to vascular tonus improvement in exercise-trained rats with chronic nitric oxide synthase inhibition.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Carbon Monoxide; Citrate (si)-Synthase; Heme Oxygenase (De | 2017 |
Role of nitric oxide and carbon monoxide in N(omega)-Nitro-L-arginine methyl ester-resistant acetylcholine-induced relaxation in chicken carotid artery.
Topics: Acetylcholine; Animals; Carbon Monoxide; Carotid Arteries; Chickens; Endothelium, Vascular; Muscle R | 2008 |
Modulation of heme oxygenase/carbon monoxide system affects the inhibitory neurotransmission involved in gastrointestinal motility of streptozotocin-treated diabetic rats.
Topics: Animals; Blotting, Western; Carbon Monoxide; Diabetes Complications; Diabetes Mellitus, Experimental | 2008 |
Inhaled ammonium persulphate inhibits non-adrenergic, non-cholinergic relaxations in the guinea pig isolated trachea.
Topics: Administration, Inhalation; Ammonium Sulfate; Animals; Carbachol; Carbon Monoxide; Cell Count; Choli | 2010 |
Nitric oxide and carbon monoxide act as inhibitory neurotransmitters in the longitudinal muscle of C57BL/6J mouse distal colon.
Topics: Animals; Atropine; Carbon Monoxide; Colon; Cyclic GMP; Electric Stimulation; Guanethidine; Guanylate | 2010 |
Divergent molecular mechanisms underlay CO- and CORM-2-induced relaxation of corpora cavernosa.
Topics: Animals; Carbon Monoxide; Guanosine Monophosphate; Guanylate Cyclase; Male; Mice; Muscle Relaxation; | 2012 |
Non-specific abdominal pain and air pollution: a novel association.
Topics: Abdominal Pain; Adolescent; Adult; Age Factors; Air Pollutants; Air Pollution; Animals; Carbon Monox | 2012 |
Investigation of the potential modulatory effect of biliverdin, carbon monoxide and bilirubin on nitrergic neurotransmission in the pig gastric fundus.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Dose-Response Relationship, Drug; Enzyme Inhibitor | 2002 |
Mechanism of internal anal sphincter relaxation by CORM-1, authentic CO, and NANC nerve stimulation.
Topics: Anal Canal; Animals; Autonomic Nervous System; Blotting, Western; Carbon Monoxide; Dose-Response Rel | 2004 |
Evidence for an apamin-sensitive, but not purinergic, component in the nonadrenergic noncholinergic relaxation of the rat gastric fundus.
Topics: Adenosine Triphosphate; Animals; Apamin; Carbon Monoxide; Dose-Response Relationship, Drug; Female; | 2004 |
Nitric oxide not carbon monoxide mediates nonadrenergic noncholinergic relaxation in the murine internal anal sphincter.
Topics: Acetylcholine; Anal Canal; Animals; Carbon Monoxide; Electric Stimulation; Enzyme Inhibitors; Epinep | 2005 |
Treatment with hypotensive agents affects the impaired relaxation of the penile corpus cavernosum in hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Carbon Monoxide; Cyclic GMP; Electric | 2006 |
Role of carbon monoxide in electrically induced non-adrenergic, non-cholinergic relaxations in the guinea-pig isolated whole trachea.
Topics: Animals; Carbon Monoxide; Electric Stimulation; Guinea Pigs; Heme Oxygenase (Decyclizing); Immunohis | 2007 |
Mechanisms of relaxation by carbon monoxide-releasing molecule-2 in murine gastric fundus and jejunum.
Topics: Animals; Carbon Monoxide; Gastric Fundus; In Vitro Techniques; Isometric Contraction; Jejunum; Male; | 2007 |
Light-dependent effects of zinc protoporphyrin IX on endothelium-dependent relaxation resistant to N omega-nitro-L-arginine.
Topics: Acetylcholine; Animals; Arginine; Benzopyrans; Biliverdine; Carbon Monoxide; Cromakalim; Darkness; E | 1994 |
Lack of effect of carbon monoxide inhibitor on relaxation induced by electrical field stimulation in corpus cavernosum.
Topics: Animals; Carbon Monoxide; Deuteroporphyrins; Electric Stimulation; Heme Oxygenase (Decyclizing); In | 1994 |
Inhibitory effect of CO on internal anal sphincter: heme oxygenase inhibitor inhibits NANC relaxation.
Topics: Anal Canal; Animals; Arginine; Carbon Monoxide; Cyclic AMP; Cyclic GMP; Electric Stimulation; Female | 1993 |
Localization and activity of haem oxygenase and functional effects of carbon monoxide in the feline lower oesophageal sphincter.
Topics: Animals; Carbon Monoxide; Cats; Cyclic GMP; Esophagogastric Junction; Heme Oxygenase (Decyclizing); | 1996 |
Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cyclic GMP; Cyto | 1996 |
Carbon monoxide formation in the ductus arteriosus in the lamb: implications for the regulation of muscle tone.
Topics: Age Factors; Animals; Blotting, Western; Carbon Monoxide; Ductus Arteriosus; Enzyme Inhibitors; Fetu | 1997 |
Carbon monoxide-induced relaxation and distribution of haem oxygenase isoenzymes in the pig urethra and lower oesophagogastric junction.
Topics: Animals; Carbon Monoxide; Cyclic AMP; Cyclic GMP; Esophagogastric Junction; Heme Oxygenase (Decycliz | 1997 |
Carbon monoxide-induced vasorelaxation and the underlying mechanisms.
Topics: Animals; Arteries; Calcium; Carbon Monoxide; Cell Membrane; Cyclic GMP; Hemin; In Vitro Techniques; | 1997 |
The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ) inhibits relaxation of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate.
Topics: Animals; Aorta; Carbon Monoxide; Enzyme Inhibitors; Guanylate Cyclase; Muscle Relaxation; Muscle, Sm | 1997 |
Mediators and mechanisms of relaxation in rabbit urethral smooth muscle.
Topics: Animals; Antibodies; Carbon Monoxide; Female; Immunohistochemistry; In Vitro Techniques; Membrane Po | 1998 |
Inhibitory effect of zinc protoporphyrin IX on lower esophageal sphincter smooth muscle relaxation by vasoactive intestinal polypeptide and other receptor agonists.
Topics: Animals; Bethanechol; Carbon Monoxide; Colforsin; Esophagogastric Junction; Heme Oxygenase (Decycliz | 1998 |
Pituitary adenylate cyclase activating peptide induces cGMP-mediated relaxation in guinea-pig airways.
Topics: Analysis of Variance; Animals; Carbon Monoxide; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Muscle | 1998 |
Relaxation of rabbit lower urinary tract smooth muscle by nitric oxide and carbon monoxide: modulation by hydrogen peroxide.
Topics: Animals; Carbon Monoxide; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Hydrog | 2000 |
Carbon monoxide and nitric oxide as coneurotransmitters in the enteric nervous system: evidence from genomic deletion of biosynthetic enzymes.
Topics: Animals; Carbon Monoxide; Electric Stimulation; Enteric Nervous System; Gene Deletion; Gene Targetin | 2000 |
Potentiation of carbon monoxide-induced relaxation of rat aorta by YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole].
Topics: Animals; Aorta, Thoracic; Carbon Monoxide; Drug Synergism; Guanylate Cyclase; In Vitro Techniques; I | 2000 |
Endothelin-1 release from the lamb ductus arteriosus: are carbon monoxide and nitric oxide regulatory agents?
Topics: Aminoquinolines; Animals; Carbon Monoxide; Cyclic AMP; Ductus Arteriosus; Endothelin-1; Endotoxins; | 2000 |
Relaxant effects of carbon monoxide compared with nitric oxide in pulmonary and systemic vessels of newborn piglets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Animals, | 2000 |
Mechanism of carbon monoxide-induced relaxation in the guinea pig ileal smooth muscle.
Topics: Animals; Calcium; Calcium Channels; Carbon Monoxide; Cyclic GMP; Dose-Response Relationship, Drug; D | 2001 |
The induction of carbon monoxide-mediated airway relaxation by PACAP 38 in isolated guinea pig airways.
Topics: Animals; Carbon Monoxide; Cyclic GMP; Guinea Pigs; Heme Oxygenase (Decyclizing); Male; Muscle Relaxa | 2001 |
Cooling is a potent vasodilator of deep vessels in the rat.
Topics: Animals; Aorta, Thoracic; Carbon Monoxide; Cold Temperature; Endothelium, Vascular; In Vitro Techniq | 2001 |
Relaxation of canine gallbladder to nerve stimulation involves adrenergic and non-adrenergic non-cholinergic mechanisms.
Topics: Adrenergic Fibers; Animals; Atropine; Autonomic Nervous System; Carbon Monoxide; Dogs; Electric Stim | 2001 |
Carbon monoxide relaxes the female pig urethra as effectively as nitric oxide in the presence of YC-1.
Topics: Animals; Carbon Monoxide; Electric Stimulation; Enzyme Activators; Female; Indazoles; Muscle Relaxat | 2002 |
Carbon monoxide relaxes ileal smooth muscle through activation of guanylate cyclase.
Topics: Acetylcholine; Animals; Carbon Monoxide; Cyclic GMP; Guanylate Cyclase; Guinea Pigs; In Vitro Techni | 1991 |
Study on the mechanism of carbon monoxide induced endothelium-independent relaxation in porcine coronary artery and vein.
Topics: Animals; Carbon Monoxide; Coronary Vessels; Cyclic GMP; Dinoprost; Enzyme Activation; Guanylate Cycl | 1990 |
Similar endothelium-independent arterial relaxation by carbon monoxide and nitric oxide.
Topics: Animals; Carbon Monoxide; Dogs; Endothelium; Femoral Artery; Muscle Relaxation; Nitric Oxide | 1989 |
Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.
Topics: Acetylcholine; Animals; Biological Products; Bradykinin; Carbon Monoxide; Cattle; Cyclic GMP; Endoth | 1987 |