Page last updated: 2024-10-16

carbon monoxide and Muscle Contraction

carbon monoxide has been researched along with Muscle Contraction in 40 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" An effective dosing regimen was then selected for testing in swine."5.33Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus. ( Bauer, AJ; Choi, AM; Ifedigbo, E; Moore, BA; Otterbein, LE; Overhaus, M; Whitcomb, J, 2005)
" In thoracic aortic rings from CH rats, cumulative dose-response curves to phenylephrine (PE) in the presence of the nitric oxide (NO) synthase inhibitor Nomega-nitro-L-arginine (L-NNA) and the HO inhibitor zinc protoporphyrin 9 (ZnPPIX) elicited increased contractility compared with CH rings treated with only L-NNA."5.30Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. ( Caudill, TK; Kanagy, NL; Resta, TC; Walker, BR, 1998)
"Hypertension was induced by N-nitro-l-arginine methyl ester (25 mg/kg/day in drinking water), and exercise training comprised swimming 1 h/day, 5 days/week, for 6 weeks."1.46Carbon monoxide does not contribute to vascular tonus improvement in exercise-trained rats with chronic nitric oxide synthase inhibition. ( Koçer, G; Şentürk, ÜK; Ülker, SN, 2017)
"Carbon monoxide (CO) has gained recent attention as therapy to reduce the deleterious effects of CPB."1.36Impairment of diaphragm muscle force and neuromuscular transmission after normothermic cardiopulmonary bypass: effect of low-dose inhaled CO. ( Atchison, FW; Ereth, MH; Ermilov, LG; Mantilla, CB; Pulido, JN; Sieck, GC; Zhan, WZ, 2010)
" An effective dosing regimen was then selected for testing in swine."1.33Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus. ( Bauer, AJ; Choi, AM; Ifedigbo, E; Moore, BA; Otterbein, LE; Overhaus, M; Whitcomb, J, 2005)
"Eighteen subjects with IDDM and 14 normal control subjects were studied."1.30Glycemic control and cardiopulmonary function in patients with insulin-dependent diabetes mellitus. ( Hsia, CC; McBrayer, DG; Niranjan, V; Ramirez, LC; Raskin, P, 1997)
"Carbon monoxide (CO) has been postulated to be a messenger in the gastrointestinal tract."1.30Distribution of heme oxygenase and effects of exogenous carbon monoxide in canine jejunum. ( Farrugia, G; Liu, X; Maines, MD; Miller, SM; Rae, JL; Rich, A; Szurszewski, JH, 1998)
" In thoracic aortic rings from CH rats, cumulative dose-response curves to phenylephrine (PE) in the presence of the nitric oxide (NO) synthase inhibitor Nomega-nitro-L-arginine (L-NNA) and the HO inhibitor zinc protoporphyrin 9 (ZnPPIX) elicited increased contractility compared with CH rings treated with only L-NNA."1.30Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. ( Caudill, TK; Kanagy, NL; Resta, TC; Walker, BR, 1998)
"Metyrapone was also a relaxant agent, and its action was greater at low than at high PO2."1.27Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus. ( Coceani, F; Hamilton, NC; Labuc, J; Olley, PM, 1984)
"Carbon monoxide relaxation was reversed by illumination with monochromatic light and the peak for the photoactivated contraction occurred at 450 nm."1.27Further evidence implicating a cytochrome P-450-mediated reaction in the contractile tension of the lamb ductus arteriosus. ( Breen, CA; Coceani, F; Falck, JR; Lees, JG; Olley, PM, 1988)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199014 (35.00)18.7374
1990's11 (27.50)18.2507
2000's8 (20.00)29.6817
2010's7 (17.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhao, H1
Jiang, R1
Smagliy, LV1
Yartseva, YO1
Rydchenko, VS1
Birulina, YG1
Gusakova, SV2
Kovalev, IV1
Petrova, IV1
Nosarev, AV1
Baskakov, MB1
Zheludeva, AS1
Smagliĭ, LV1
Aleĭnik, AN1
Ianchuk, PI1
Medvedev, MA1
Orlov, SN1
Martín-Cano, FE1
Camello, PJ1
Pozo, MJ1
Ülker, SN1
Koçer, G1
Şentürk, ÜK1
Dellabianca, A1
Faniglione, M1
De Angelis, S1
Colucci, M1
Cervio, M1
Balestra, B1
Tonini, S1
Candura, SM1
Ermilov, LG1
Pulido, JN1
Atchison, FW1
Zhan, WZ1
Ereth, MH1
Sieck, GC1
Mantilla, CB1
Samb, A1
Taillé, C1
Almolki, A1
Mégret, J1
Staddon, JM1
Aubier, M1
Boczkowski, J1
Nakao, A2
Moore, BA2
Murase, N2
Liu, F2
Zuckerbraun, BS1
Bach, FH2
Choi, AM2
Nalesnik, MA2
Otterbein, LE3
Bauer, AJ3
Szurszewski, JH2
Farrugia, G2
Overhaus, M2
Sarady, JK1
Tsung, A1
Kimizuka, K1
Kaizu, T1
Uchiyama, T1
Whitcomb, J1
Ifedigbo, E1
Di Pascoli, M1
Rodella, L1
Sacerdoti, D1
Bolognesi, M1
Turkseven, S1
Abraham, NG1
Coceani, F5
Hamilton, NC2
Labuc, J1
Olley, PM3
Constantinides, P1
Ny, L2
Grundemar, L1
Larsson, B3
Alm, P3
Ekström, P1
Andersson, KE3
Kelsey, L1
Seidlitz, E1
Montagnani, M1
Serio, M1
Potenza, MA1
Mansi, G1
Salvia, MA1
Cagiano, R1
Cuomo, V1
Mitolo-Chieppa, D1
Iselin, CE2
Schaad, NC2
Graber, P2
Niranjan, V1
McBrayer, DG1
Ramirez, LC1
Raskin, P1
Hsia, CC1
Canning, BJ1
Fischer, A1
Miller, SM1
Rich, A1
Liu, X1
Maines, MD1
Rae, JL1
Morel, DR1
Caudill, TK1
Resta, TC1
Kanagy, NL1
Walker, BR1
Longo, M1
Jain, V1
Vedernikov, YP1
Saade, GR1
Goodrum, L1
Facchinetti, F1
Garfield, RE1
Villamor, E1
Pérez-Vizcaíno, F1
Cogolludo, AL1
Conde-Oviedo, J1
Zaragozá-Arnáez, F1
López-López, JG1
Tamargo, J1
Komuro, T1
Borsody, MK1
Ono, S1
Marton, LS1
Weir, BK1
Zhang, ZD1
Paik, E1
Macdonald, RL1
Coburn, RF1
Fay, FS3
Nair, P1
Whalen, WJ1
King, CE2
Breen, CA1
Lees, JG1
Falck, JR1
Huhtanen, D1
Bishai, I1
Dodd, SL1
Cain, SM1
Crocker, AD1
Wilson, KA1
Spike, TE1
Aust, SD1
Chandler, JT1
Strong, CG1
Gokina, MS1
Jöbsis, FF1
Wolfe, LS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253]Phase 344 participants (Anticipated)Interventional2016-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for carbon monoxide and Muscle Contraction

ArticleYear
[Relaxation mechanism of smooth muscle cells and its relationship with penile erection].
    Zhonghua nan ke xue = National journal of andrology, 2016, Volume: 22, Issue:9

    Topics: Carbon Monoxide; Erectile Dysfunction; Humans; Hydrogen Sulfide; Male; Muscle Contraction; Muscle, S

2016
Carbon monoxide is an endogenous hyperpolarizing factor in the gastrointestinal tract.
    Neurogastroenterology and motility, 2004, Volume: 16 Suppl 1

    Topics: Animals; Carbon Monoxide; Digestive System; Enteric Nervous System; Gastrointestinal Motility; Human

2004

Trials

1 trial available for carbon monoxide and Muscle Contraction

ArticleYear
The nitric oxide synthase/nitric oxide and heme oxygenase/carbon monoxide pathways in the human ureter.
    European urology, 1998, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Cadaver; Carbon Monoxide; Child; Culture Techniques; Female; Heme Oxygenase

1998

Other Studies

37 other studies available for carbon monoxide and Muscle Contraction

ArticleYear
Role of Carbon Monoxide in the Mechanisms of Action of Extracellular ATP on Contractile Activity of Vascular Smooth Muscle Cells.
    Bulletin of experimental biology and medicine, 2019, Volume: 167, Issue:3

    Topics: Adenosine Triphosphate; Animals; Aorta; Carbon Monoxide; Cells, Cultured; Endothelium; Muscle Contra

2019
[Ionic mechanisms of carbon monoxide action on the contractile properties of smooth muscles of the blood vessels].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2013, Volume: 59, Issue:3

    Topics: Animals; Aorta; Calcium; Calcium Channels, L-Type; Calcium Radioisotopes; Carbon Monoxide; Ion Chann

2013
Characterization of the motor inhibitory role of colonic mucosa under chemical stimulation in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Apr-01, Volume: 306, Issue:7

    Topics: Animals; Bethanechol; Carbon Monoxide; Colon; Enzyme Inhibitors; Female; Gasotransmitters; Gastroint

2014
Carbon monoxide does not contribute to vascular tonus improvement in exercise-trained rats with chronic nitric oxide synthase inhibition.
    Nitric oxide : biology and chemistry, 2017, 05-01, Volume: 65

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Carbon Monoxide; Citrate (si)-Synthase; Heme Oxygenase (De

2017
Inhaled ammonium persulphate inhibits non-adrenergic, non-cholinergic relaxations in the guinea pig isolated trachea.
    Respiration; international review of thoracic diseases, 2010, Volume: 79, Issue:5

    Topics: Administration, Inhalation; Ammonium Sulfate; Animals; Carbachol; Carbon Monoxide; Cell Count; Choli

2010
Impairment of diaphragm muscle force and neuromuscular transmission after normothermic cardiopulmonary bypass: effect of low-dose inhaled CO.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:3

    Topics: Administration, Inhalation; Animals; Antimetabolites; Body Temperature; Carbon Dioxide; Carbon Monox

2010
Heme oxygenase modulates oxidant-signaled airway smooth muscle contractility: role of bilirubin.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 283, Issue:3

    Topics: Animals; Bilirubin; Carbon Monoxide; Cyclic GMP; Epithelium; Guinea Pigs; Heme Oxygenase (Decyclizin

2002
Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility.
    Gut, 2003, Volume: 52, Issue:9

    Topics: Animals; Bethanechol; Blotting, Northern; Carbon Monoxide; Cyclooxygenase 2; Cytokines; Gastrointest

2003
Biliverdin protects the functional integrity of a transplanted syngeneic small bowel.
    Gastroenterology, 2004, Volume: 127, Issue:2

    Topics: Animals; Anti-Infective Agents; Bilirubin; Biliverdine; Carbon Monoxide; Enteritis; Graft Survival;

2004
Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus.
    Critical care medicine, 2005, Volume: 33, Issue:6

    Topics: Administration, Inhalation; Analgesics, Opioid; Analysis of Variance; Animals; Carbon Monoxide; Colo

2005
Chronic CO levels have [corrected] a beneficial effect on vascular relaxation in diabetes.
    Biochemical and biophysical research communications, 2006, Feb-17, Volume: 340, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Biliverdine; Blotting, Western; Carbon Monoxide; Chromium; Densitomet

2006
Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus.
    The American journal of physiology, 1984, Volume: 246, Issue:4 Pt 2

    Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Female; Guinea Pigs; In

1984
[The arterial endothelium--present state of knowledge].
    Wiener klinische Wochenschrift, 1982, Dec-10, Volume: 94, Issue:23

    Topics: Acetates; Angiotensin II; Animals; Arteries; Arteriosclerosis; Carbon Monoxide; Cyanides; Endotheliu

1982
Carbon monoxide as a putative messenger molecule in the feline lower oesophageal sphincter of the cat.
    Neuroreport, 1995, Jul-10, Volume: 6, Issue:10

    Topics: Animals; Carbon Monoxide; Cats; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Esophagogastric Junction;

1995
Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase.
    British journal of pharmacology, 1996, Volume: 118, Issue:7

    Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cyclic GMP; Cyto

1996
Prenatal exposure to carbon monoxide and vascular responsiveness of rat resistance vessels.
    Life sciences, 1996, Volume: 59, Issue:18

    Topics: Acetylcholine; Animals; Blood Vessels; Carbon Monoxide; Female; Male; Mesentery; Muscle Contraction;

1996
Localization of nitric oxide synthase and haemoxygenase, and functional effects of nitric oxide and carbon monoxide in the pig and human intravesical ureter.
    Neurourology and urodynamics, 1997, Volume: 16, Issue:3

    Topics: Adult; Aged; Animals; Carbon Monoxide; Female; Heme Oxygenase (Decyclizing); Humans; Immunohistochem

1997
Glycemic control and cardiopulmonary function in patients with insulin-dependent diabetes mellitus.
    The American journal of medicine, 1997, Volume: 103, Issue:6

    Topics: Adult; Blood Pressure; Carbon Monoxide; Diabetes Mellitus, Type 1; Drug Administration Schedule; Exe

1997
Localization of heme oxygenase-2 immunoreactivity to parasympathetic ganglia of human and guinea-pig airways.
    American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:2

    Topics: Animals; Atropine; Carbon Monoxide; Cyclic GMP; Enzyme Inhibitors; Female; Ganglia, Parasympathetic;

1998
Distribution of heme oxygenase and effects of exogenous carbon monoxide in canine jejunum.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Alkaloids; Animals; Carbazoles; Carbon Monoxide; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; D

1998
Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Aorta, Thoracic; Arsenites; Carbon Monoxide; Endothelium, Vascular; Enzyme Inhibitors; Guan

1998
Effect of nitric oxide and carbon monoxide on uterine contractility during human and rat pregnancy.
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:4

    Topics: Adult; Animals; Aorta; Arteries; Biopsy; Carbon Monoxide; Cesarean Section; Female; Gestational Age;

1999
Relaxant effects of carbon monoxide compared with nitric oxide in pulmonary and systemic vessels of newborn piglets.
    Pediatric research, 2000, Volume: 48, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Animals,

2000
The vasorelaxation of cerebral arteries by carbon monoxide.
    Experimental biology and medicine (Maywood, N.J.), 2001, Volume: 226, Issue:9

    Topics: Animals; Carbon Monoxide; Cerebral Arteries; Dinoprost; Dogs; Enzyme Inhibitors; Guanylate Cyclase;

2001
Oxygen tension sensors in vascular smooth muscle.
    Advances in experimental medicine and biology, 1977, Volume: 78

    Topics: Adenosine Triphosphate; Animals; Aorta; Carbon Monoxide; Cyanides; Cytochromes; Energy Metabolism; H

1977
Mechanism of oxygen induced contraction of ductus arteriosus.
    Advances in experimental medicine and biology, 1977, Volume: 78

    Topics: Acetylcholine; Animals; Atmospheric Pressure; Carbon Monoxide; Cytochromes; Ductus Arteriosus; Energ

1977
Muscle oxygenation and performance during low level carbon monoxide exposure.
    Advances in experimental medicine and biology, 1990, Volume: 277

    Topics: Animals; Blood Flow Velocity; Carbon Monoxide; Carboxyhemoglobin; Dogs; Lactates; Lactic Acid; Male;

1990
Further evidence implicating a cytochrome P-450-mediated reaction in the contractile tension of the lamb ductus arteriosus.
    Circulation research, 1988, Volume: 62, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; C

1988
Involvement of intramural prostaglandin E2 in prenatal patency of the lamb ductus arteriosus.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:6

    Topics: Animals; Carbon Monoxide; Dinoprostone; Ductus Arteriosus; Female; Fetus; Glutathione; Indomethacin;

1986
O2 delivery to contracting muscle during hypoxic or CO hypoxia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:2

    Topics: Animals; Biological Availability; Blood Gas Analysis; Blood Pressure; Carbon Monoxide; Dogs; Hypoxia

1987
A study of the metabolic requirements for the contractile action of angiotensin upon guinea-pig ileum.
    British journal of pharmacology, 1974, Volume: 51, Issue:1

    Topics: Acetylcholine; Adenosine Triphosphate; Angiotensin II; Animals; Carbon Monoxide; Electric Stimulatio

1974
Activation of slaframine by liver microsomes and flavins.
    Biochemical pharmacology, 1971, Volume: 20, Issue:4

    Topics: Acetylcholine; Alkaloids; Animals; Atropine; Basidiomycota; Biological Assay; Carbon Monoxide; Cell

1971
The actions of prostaglandin E 1 on isolated rabbit aorta.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 197, Issue:1

    Topics: Animals; Aorta; Ascorbic Acid; Azides; Bretylium Compounds; Carbon Monoxide; Cyanides; Drug Antagoni

1972
[Contractile capacity of the myocardium in workers subjected to prolonged exposures of small concentrations of carbon monoxide].
    Vrachebnoe delo, 1971, Volume: 8

    Topics: Adult; Carbon Monoxide; Carbon Monoxide Poisoning; Chemical Industry; Heart; Heart Function Tests; H

1971
Guinea pig ductus arteriosus. 3. Light absorption changes during response to O 2 .
    The American journal of physiology, 1972, Volume: 223, Issue:3

    Topics: Animals; Biomechanical Phenomena; Carbon Monoxide; Cytochromes; Ductus Arteriosus; Electron Transpor

1972
Guinea pig ductus arteriosus. I. Cellular and metabolic basis for oxygen sensitivity.
    The American journal of physiology, 1971, Volume: 221, Issue:2

    Topics: Acetylcholine; Animals; Animals, Newborn; Carbon Monoxide; Chlorobutanol; Cyanides; Dinitrophenols;

1971
On the action of prostaglandin E1 and prostaglandins from brain on the isolated rat stomach.
    Canadian journal of physiology and pharmacology, 1966, Volume: 44, Issue:6

    Topics: Acetylcholine; Anesthetics, Local; Animals; Ascorbic Acid; Azides; Brain; Bretylium Compounds; Calci

1966