Page last updated: 2024-10-16

carbon monoxide and Mood Disorders

carbon monoxide has been researched along with Mood Disorders in 3 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.

Research Excerpts

ExcerptRelevanceReference
"Results from this study will inform FDA on the potential effects of regulating the nicotine content of cigarettes and help determine whether smokers with mood and/or anxiety disorders can safely transition to significantly reduced nicotine content cigarettes."9.24A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol. ( Allen, SI; Azzouz, N; Cather, C; Evins, AE; Foulds, J; Hameed, A; Hammett, E; Hrabovsky, S; Krebs, NM; Liao, J; Modesto, J; Muscat, JE; Pachas, GN; Richie, J; Veldheer, S; Yingst, J; Zhu, J, 2017)
"Results from this study will inform FDA on the potential effects of regulating the nicotine content of cigarettes and help determine whether smokers with mood and/or anxiety disorders can safely transition to significantly reduced nicotine content cigarettes."5.24A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol. ( Allen, SI; Azzouz, N; Cather, C; Evins, AE; Foulds, J; Hameed, A; Hammett, E; Hrabovsky, S; Krebs, NM; Liao, J; Modesto, J; Muscat, JE; Pachas, GN; Richie, J; Veldheer, S; Yingst, J; Zhu, J, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Minami, H1
Nahvi, S1
Arnsten, JH1
Brinkman, HR1
Rivera-Mindt, M1
Wetter, DW1
Bloom, EL1
Price, LH1
Richman, EK1
Betzler, TF1
Stockmal, C1
Donnelly, R1
McClain, LM1
Kennedy, KA1
Vieira, C1
Fine, M1
McCarthy, DE1
Thomas, JG1
Hecht, J1
Brown, RA1
Brunette, MF1
Ferron, JC1
Drake, RE1
Devitt, TS1
Geiger, PT1
McHugo, GJ1
Jonikas, JA1
Cook, JA1
Allen, SI1
Foulds, J1
Pachas, GN1
Veldheer, S1
Cather, C1
Azzouz, N1
Hrabovsky, S1
Hameed, A1
Yingst, J1
Hammett, E1
Modesto, J1
Krebs, NM1
Zhu, J1
Liao, J1
Muscat, JE1
Richie, J1
Evins, AE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Brief Mindfulness Cessation Training With EMA for Post-hospital Depressed Smokers[NCT02742610]60 participants (Actual)Interventional2015-11-30Completed
Reduced Nicotine Cigarettes in Smokers With Mood and Anxiety Disorders[NCT01928758]245 participants (Actual)Interventional2015-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Abstinence From Smoking

Smokers assigned to reduced nicotine content cigarettes will be more likely to successfully abstain from smoking at the end of the trial, based on all randomized participants, defined as no cigarette use in past 7 days, verified by exhaled carbon monoxide <10ppm. (NCT01928758)
Timeframe: Follow-up appointment 30 weeks after randomization (12 weeks after last visit of randomized trial phase).

InterventionParticipants (Count of Participants)
Reduced Nicotine Content Cigarettes17
Usual Nicotine Content Cigarettes4

Intention to Quit Smoking

Smokers assigned to the reduced nicotine content cigarette group may have lower perceived dependence and be more likely to report intention to quit smoking (NCT01928758)
Timeframe: At end of 18-week randomized trial phase

InterventionParticipants (Count of Participants)
Reduced Nicotine Content Cigarettes33
Usual Nicotine Content Cigarettes25

Minnesota Nicotine Withdrawal Scale

This 8-item scale measures nicotine withdrawal symptoms and the scale range is from 0-32. Higher scores indicate higher severity. (NCT01928758)
Timeframe: Measured at the end of the last 3 weeks of randomization trial phase

Interventionscore on a scale (Mean)
Reduced Nicotine Content Cigarettes8.1
Usual Nicotine Content Cigarettes9.0

Perceived Stress Scale

10-item questionnaire measuring the degree to which life situations are appraised stressful. Scale range is 0-40. Higher scores indicate more stress. (NCT01928758)
Timeframe: Measured at the end of the last 3 weeks of randomization trial phase

Interventionscore on a scale (Mean)
Reduced Nicotine Content Cigarettes15.0
Usual Nicotine Content Cigarettes15.1

Plasma Cotinine Concentration

Plasma cotinine is a measure of daily nicotine exposure. Samples were measured in ng/mL. (NCT01928758)
Timeframe: Measured at the end of the last 3 weeks of randomization trial phase

Interventionng/mL (Mean)
Reduced Nicotine Content Cigarettes82.8
Usual Nicotine Content Cigarettes259.0

Quick Inventory of Depressive Symptomatology

A 16-item scale on depression symptoms. The scale range is 0-27 where 0 = Least Severe and 27 = Most Severe. (NCT01928758)
Timeframe: Measured at the end of the last 3 weeks of randomization trial phase

Interventionscore on a scale (Mean)
Reduced Nicotine Content Cigarettes5.5
Usual Nicotine Content Cigarettes5.3

Trials

3 trials available for carbon monoxide and Mood Disorders

ArticleYear
A pilot randomized controlled trial of smartphone-assisted mindfulness-based intervention with contingency management for smokers with mood disorders.
    Experimental and clinical psychopharmacology, 2022, Volume: 30, Issue:5

    Topics: Adult; Carbon Monoxide; Humans; Mindfulness; Mood Disorders; Pilot Projects; Smartphone; Smokers; Sm

2022
Carbon monoxide feedback in a motivational decision support system for nicotine dependence among smokers with severe mental illnesses.
    Journal of substance abuse treatment, 2013, Volume: 45, Issue:4

    Topics: Adult; Behavior Therapy; Carbon Monoxide; Decision Support Techniques; Feedback; Female; Humans; Mal

2013
A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol.
    BMC public health, 2017, 01-19, Volume: 17, Issue:1

    Topics: Adult; Anxiety Disorders; Biomarkers; Carbon Monoxide; Clinical Protocols; Cotinine; Double-Blind Me

2017