carbon monoxide has been researched along with Methemoglobinemia in 12 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the first group, IV administration of approximately 300 mg sodium nitrite increased subjects' methemoglobin level to a 7% to 8% target and hypoxia was induced to different levels of Sao2 (70%-100%) by varying fractional inspired oxygen." | 3.76 | Accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia. ( Bickler, PE; Feiner, JR; Mannheimer, PD, 2010) |
| " Carbon monoxide-oximetry may falsely identify sulfhemoglobin as methemoglobin; sulfhemoglobinemia should be considered in cases of methemoglobinemia refractory to methylene blue therapy." | 3.70 | Sulfhemoglobinemia after dermal application of DMSO. ( Burgess, JL; Hamner, AP; Robertson, WO, 1998) |
| "Methylene blue is an agent thought to help reverse the effects of methemoglobinemia by facilitating the methemoglobin reductase system." | 2.49 | Methemoglobinemia in bronchoscopy: a case series and a review of the literature. ( Bowling, M; Brown, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, C | 1 |
| Bowling, M | 1 |
| Moriya, F | 1 |
| Vevelstad, M | 1 |
| Morild, I | 1 |
| Feiner, JR | 1 |
| Bickler, PE | 1 |
| Mannheimer, PD | 1 |
| Darracq, MA | 1 |
| Daubert, GP | 1 |
| Power, GG | 1 |
| Bragg, SL | 1 |
| Oshiro, BT | 1 |
| Dejam, A | 1 |
| Hunter, CJ | 1 |
| Blood, AB | 1 |
| Sladen, RN | 1 |
| Burgess, JL | 1 |
| Hamner, AP | 1 |
| Robertson, WO | 1 |
| Taylor, JH | 1 |
| Guthrie, AJ | 1 |
| Leisewitz, A | 1 |
| Ayres, SM | 1 |
| Evans, R | 1 |
| Licht, D | 1 |
| Griesbach, J | 1 |
| Reimold, F | 1 |
| Ferrand, EF | 1 |
| Criscitiello, A | 1 |
| Pilz, W | 1 |
| Johann, I | 1 |
| Boo, AT | 1 |
| Gregory, IC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pulse Oximeter Accuracy in Healthy Humans During Hypoxia[NCT06142019] | 10,000 participants (Anticipated) | Observational | 2024-01-01 | Recruiting | |||
| Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Prilocaine Versus Lidocaine[NCT01402869] | 91 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in percentage of methemoglobin in blood from baseline level to peak level (NCT01402869)
Timeframe: From administration of local anesthetic or start of restorative procedures to time at which maximum methemoglobin blood level was documented during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 2.73 |
| Lidocaine | 0.78 |
| No Local Anesthetic | 0.76 |
The maximum percentage of methemoglobin in blood (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 3.55 |
| Lidocaine | 1.63 |
| No Local Anesthetic | 1.60 |
The length of time between the administration of local anesthetic (Prilocaine and Lidocaine Groups) or start of restorative dental procedures (No local anesthetic Group) and the time at which the maximum methemoglobin blood level is observed. (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | minutes (Mean) |
|---|---|
| Prilocaine | 62.73 |
| Lidocaine | 57.50 |
| No Local Anesthetic | 29.50 |
3 reviews available for carbon monoxide and Methemoglobinemia
| Article | Year |
|---|---|
Methemoglobinemia in bronchoscopy: a case series and a review of the literature.
Topics: Adult; Anesthetics, Local; Benzocaine; Bronchoscopy; Carbon Monoxide; Child; Cyanosis; Humans; Methe | 2013 |
[Poisoning due to carbon monoxide and cyanide gas generated in the occurrence of fire].
Topics: Autopsy; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Cyanides; Fires; Forensic Me | 2015 |
The oxyhemoglobin dissociation curve.
Topics: Adaptation, Physiological; Altitude; Anesthesiology; Blood Preservation; Blood Transfusion; Carbon D | 1981 |
9 other studies available for carbon monoxide and Methemoglobinemia
| Article | Year |
|---|---|
Lethal methemoglobinemia and automobile exhaust inhalation.
Topics: Adult; Autopsy; Carbon Monoxide; Fatal Outcome; Humans; Male; Methemoglobin; Methemoglobinemia; Suic | 2009 |
Accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia.
Topics: Adult; Blood Gas Analysis; Carbon Monoxide; Carboxyhemoglobin; Data Interpretation, Statistical; Fem | 2010 |
Accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia.
Topics: Adult; Blood Gas Analysis; Carbon Monoxide; Carboxyhemoglobin; Data Interpretation, Statistical; Fem | 2010 |
Accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia.
Topics: Adult; Blood Gas Analysis; Carbon Monoxide; Carboxyhemoglobin; Data Interpretation, Statistical; Fem | 2010 |
Accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia.
Topics: Adult; Blood Gas Analysis; Carbon Monoxide; Carboxyhemoglobin; Data Interpretation, Statistical; Fem | 2010 |
A cyanotic toddler.
Topics: Anesthetics, Local; Benzocaine; Carbon Monoxide; Child, Preschool; Cyanosis; Humans; Hypoxia; Male; | 2007 |
A novel method of measuring reduction of nitrite-induced methemoglobin applied to fetal and adult blood of humans and sheep.
Topics: Adult; Animals; Carbon Monoxide; Cytochrome-B(5) Reductase; Drug Combinations; Fetal Blood; Humans; | 2007 |
Sulfhemoglobinemia after dermal application of DMSO.
Topics: Administration, Topical; Adult; Anti-Infective Agents, Urinary; Anti-Inflammatory Agents; Carbon Mon | 1998 |
The effect of endogenously produced carbon monoxide on the oxygen status of dogs infected with Babesia canis.
Topics: Animals; Babesiosis; Carbon Monoxide; Carboxyhemoglobin; Dog Diseases; Dogs; Methemoglobinemia; Oxyg | 1991 |
Health effects of exposure to high concentrations of automotive emissions. Studies in bridge and tunnel workers in New York City.
Topics: Adult; Blood Cell Count; Blood Proteins; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglob | 1973 |
[The determination of methemoglobin in human blood].
Topics: Blood Chemical Analysis; Carbon Monoxide; Cyanides; Evaluation Studies as Topic; Humans; Methemoglob | 1973 |
The oxygen and carbon monoxide capacities of fetal and adult blood.
Topics: Adult; Blood Gas Analysis; Carbon Monoxide; Fetal Hemoglobin; Fetus; Hemoglobins; Humans; Methemoglo | 1974 |