carbon monoxide has been researched along with Malignant Melanoma in 4 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) induces DNA damage via a chloroethyl adduct at the O(6) position of guanine, which can be repaired by O(6)-alkylguanine DNA alkyltransferase (AGT) expressed in melanoma." | 9.11 | Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma. ( Dolan, E; Gajewski, TF; Gerson, SL; Lin, S; Liu, L; Sosman, J; Vokes, EE, 2005) |
| "1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) induces DNA damage via a chloroethyl adduct at the O(6) position of guanine, which can be repaired by O(6)-alkylguanine DNA alkyltransferase (AGT) expressed in melanoma." | 5.11 | Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma. ( Dolan, E; Gajewski, TF; Gerson, SL; Lin, S; Liu, L; Sosman, J; Vokes, EE, 2005) |
| " The data support the hypothesis that LAK cells have an additional toxic effect on the lung." | 1.29 | Pulmonary toxicity of recombinant interleukin-2 plus lymphokine-activated killer cell therapy. ( Galimberti, M; Manzi, R; Rizzi, M; Villani, F, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Venkatesh, Y | 1 |
| Vangala, V | 1 |
| Mengji, R | 1 |
| Chaudhuri, A | 1 |
| Bhattacharya, S | 1 |
| Datta, PK | 1 |
| Banerjee, R | 1 |
| Jana, A | 1 |
| Singh, NDP | 1 |
| Zhai, T | 1 |
| Zhong, W | 1 |
| Gao, Y | 1 |
| Zhou, H | 1 |
| Zhou, Z | 1 |
| Liu, X | 1 |
| Yang, S | 1 |
| Yang, H | 1 |
| Gajewski, TF | 1 |
| Sosman, J | 1 |
| Gerson, SL | 1 |
| Liu, L | 1 |
| Dolan, E | 1 |
| Lin, S | 1 |
| Vokes, EE | 1 |
| Villani, F | 1 |
| Galimberti, M | 1 |
| Rizzi, M | 1 |
| Manzi, R | 1 |
1 trial available for carbon monoxide and Malignant Melanoma
| Article | Year |
|---|---|
Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineopla | 2005 |
3 other studies available for carbon monoxide and Malignant Melanoma
| Article | Year |
|---|---|
One- and Two-Photon Uncaging of Carbon Monoxide (CO) with Real-Time Monitoring: On-Demand Carbazole-Based Dual CO-Releasing Platform to Test over Single and Combinatorial Approaches for the Efficient Regression of Orthotopic Murine Melanoma
Topics: Animals; Antineoplastic Agents; Apoptosis; Carbazoles; Carbon Monoxide; Cell Line, Tumor; Dioxoles; | 2022 |
Tumor Microenvironment-Activated Nanoparticles Loaded with an Iron-Carbonyl Complex for Chemodynamic Immunotherapy of Lung Metastasis of Melanoma
Topics: Animals; Antineoplastic Agents; Apoptosis; Carbon Monoxide; Cell Line, Tumor; Cell Proliferation; Dr | 2021 |
Pulmonary toxicity of recombinant interleukin-2 plus lymphokine-activated killer cell therapy.
Topics: Adult; Carbon Monoxide; Dose-Response Relationship, Drug; Female; Humans; Immunotherapy; Interleukin | 1993 |