carbon monoxide has been researched along with Injury, Myocardial Reperfusion in 30 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Heme oxygenase-1 (HO-1)-dependent carbon monoxide (CO) production related to reperfusion-induced ventricular fibrillation (VF) was studied in HO-1 wild-type (+/+), heterozygous (+/-), and homozygous (-/-) isolated ischemic/reperfused mouse heart." | 7.72 | Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic/reperfused mouse myocardium. ( Bacskay, I; Bak, I; Balla, J; Das, DK; de Leiris, J; Der, P; Joo, F; Juhasz, B; Kovacs, P; Papp, G; Szendrei, L; Tosaki, A; Turoczi, T; Varga, E, 2003) |
| "We investigated the pre-clinical utility of carbon monoxide form of PEGylated hemoglobin (PEG-Hb also named SANGUINATE(™)) in myocardial infarction (MI) and in particular the response of diabetic tissues to superimposed ischemia/reperfusion injury." | 3.79 | Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice. ( Abuchowski, A; Ananthakrishnan, R; Li, Q; O'Shea, KM; Quadri, N; Ramasamy, R; Schmidt, AM; Wang, L, 2013) |
| "Heme oxygenase-1 (HO-1)-dependent carbon monoxide (CO) production related to reperfusion-induced ventricular fibrillation (VF) was studied in HO-1 wild-type (+/+), heterozygous (+/-), and homozygous (-/-) isolated ischemic/reperfused mouse heart." | 3.72 | Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic/reperfused mouse myocardium. ( Bacskay, I; Bak, I; Balla, J; Das, DK; de Leiris, J; Der, P; Joo, F; Juhasz, B; Kovacs, P; Papp, G; Szendrei, L; Tosaki, A; Turoczi, T; Varga, E, 2003) |
| "Hydrogen treatment alone significantly reduced malondialdehyde levels and serum high-mobility group box 1 protein levels as compared with air-treated controls." | 1.36 | Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both. ( Billiar, TR; Buchholz, BM; Cardinal, JS; Kaczorowski, DJ; Lee, S; McCurry, KR; Nakao, A; Sugimoto, R; Tobita, K; Toyoda, Y; Wang, Y, 2010) |
| "Carbon monoxide (CO) carriers have been recently developed as a pharmacological tool to simulate the effect of heme oxygenase-1-derived CO." | 1.34 | Beneficial effects of carbon monoxide-releasing molecules on post-ischemic myocardial recovery. ( Bacskay, I; Bak, I; Foresti, R; Gesztelyi, R; Juhasz, B; Lekli, I; Motterlini, R; Szabo, G; Szendrei, L; Tosaki, A; Varadi, J; Varga, E, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (40.00) | 29.6817 |
| 2010's | 13 (43.33) | 24.3611 |
| 2020's | 5 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, P | 1 |
| Yu, Y | 1 |
| Wang, P | 1 |
| Shen, H | 1 |
| Ling, X | 1 |
| Xue, X | 1 |
| Yang, Q | 1 |
| Zhang, Y | 2 |
| Xiao, J | 1 |
| Wang, Z | 1 |
| Logan, SM | 1 |
| Gupta, A | 1 |
| Wang, A | 1 |
| Levy, RJ | 1 |
| Storey, KB | 1 |
| Nie, H | 1 |
| Li, S | 1 |
| Deng, Y | 1 |
| Zhou, W | 1 |
| Wu, W | 1 |
| Xu, X | 1 |
| Yu, H | 1 |
| Li, T | 1 |
| Iqbal, J | 1 |
| Chamberlain, J | 1 |
| Alfaidi, M | 1 |
| Hughes, M | 1 |
| Alizadeh, T | 1 |
| Casbolt, H | 1 |
| Evans, P | 1 |
| Mann, B | 1 |
| Motterlini, R | 5 |
| Francis, S | 1 |
| Gunn, J | 1 |
| Kumar, A | 1 |
| Boovarahan, SR | 1 |
| Prem, PN | 1 |
| Ramanathan, M | 1 |
| Chellappan, DR | 1 |
| Kurian, GA | 1 |
| Zhou, Z | 1 |
| Ma, S | 1 |
| Liu, J | 1 |
| Ji, QR | 1 |
| Cao, CZ | 1 |
| Li, XN | 1 |
| Tang, F | 1 |
| Zhang, W | 1 |
| Collino, M | 1 |
| Pini, A | 1 |
| Mugelli, N | 1 |
| Mastroianni, R | 1 |
| Bani, D | 1 |
| Fantozzi, R | 1 |
| Papucci, L | 1 |
| Fazi, M | 1 |
| Masini, E | 1 |
| Meyer, G | 3 |
| André, L | 3 |
| Kleindienst, A | 1 |
| Singh, F | 1 |
| Tanguy, S | 3 |
| Richard, S | 3 |
| Obert, P | 3 |
| Boucher, F | 3 |
| Jover, B | 1 |
| Cazorla, O | 3 |
| Reboul, C | 3 |
| Penna, C | 1 |
| Granata, R | 1 |
| Tocchetti, CG | 1 |
| Gallo, MP | 1 |
| Alloatti, G | 1 |
| Pagliaro, P | 1 |
| Vandegriff, KD | 1 |
| Young, MA | 1 |
| Lohman, J | 1 |
| Bellelli, A | 1 |
| Samaja, M | 1 |
| Malavalli, A | 1 |
| Winslow, RM | 1 |
| Burger, D | 1 |
| Xiang, F | 1 |
| Hammoud, L | 1 |
| Lu, X | 1 |
| Feng, Q | 1 |
| Yoshida, K | 1 |
| Zhu, JC | 1 |
| Shao, JL | 1 |
| Ma, H | 1 |
| Wang, JK | 1 |
| Nakao, A | 2 |
| Kaczorowski, DJ | 1 |
| Wang, Y | 2 |
| Cardinal, JS | 1 |
| Buchholz, BM | 1 |
| Sugimoto, R | 1 |
| Tobita, K | 1 |
| Lee, S | 1 |
| Toyoda, Y | 1 |
| Billiar, TR | 1 |
| McCurry, KR | 1 |
| Boissiere, J | 2 |
| Farah, C | 2 |
| Lopez-Lauri, F | 1 |
| Gayrard, S | 2 |
| Juhasz, B | 3 |
| Varga, B | 1 |
| Czompa, A | 1 |
| Bak, I | 3 |
| Lekli, I | 2 |
| Gesztelyi, R | 2 |
| Zsuga, J | 1 |
| Kemeny-Beke, A | 1 |
| Antal, M | 1 |
| Szendrei, L | 3 |
| Tosaki, A | 3 |
| Ahlström, K | 1 |
| Biber, B | 1 |
| Åberg, AM | 1 |
| Abrahamsson, P | 1 |
| Johansson, G | 1 |
| Ronquist, G | 1 |
| Waldenström, A | 1 |
| Haney, MF | 1 |
| Schibilsky, D | 1 |
| Beyersdorf, F | 1 |
| Goebel, U | 1 |
| Stein, AB | 2 |
| Bolli, R | 2 |
| Dawn, B | 2 |
| Sanganalmath, SK | 1 |
| Zhu, Y | 1 |
| Wang, OL | 1 |
| Guo, Y | 2 |
| Xuan, YT | 1 |
| Maslov, LN | 1 |
| Mrochek, AG | 1 |
| Barzakh, EI | 1 |
| Lishmanov, AIu | 1 |
| Gorbunov, AS | 1 |
| Tsibul'nikov, SIu | 1 |
| Sementsov, AS | 1 |
| Prokudina, ES | 1 |
| Ananthakrishnan, R | 1 |
| Li, Q | 1 |
| O'Shea, KM | 1 |
| Quadri, N | 1 |
| Wang, L | 1 |
| Abuchowski, A | 1 |
| Schmidt, AM | 1 |
| Ramasamy, R | 1 |
| Turoczi, T | 1 |
| Papp, G | 1 |
| Joo, F | 1 |
| Das, DK | 1 |
| de Leiris, J | 1 |
| Der, P | 1 |
| Varga, E | 2 |
| Bacskay, I | 2 |
| Balla, J | 1 |
| Kovacs, P | 1 |
| Wu, WJ | 1 |
| Tan, W | 1 |
| Zhu, X | 1 |
| Li, QH | 1 |
| Akamatsu, Y | 1 |
| Haga, M | 1 |
| Tyagi, S | 1 |
| Yamashita, K | 1 |
| Graça-Souza, AV | 1 |
| Ollinger, R | 1 |
| Czismadia, E | 1 |
| May, GA | 1 |
| Ifedigbo, E | 1 |
| Otterbein, LE | 2 |
| Bach, FH | 2 |
| Soares, MP | 1 |
| Lavitrano, M | 1 |
| Smolenski, RT | 1 |
| Musumeci, A | 1 |
| Maccherini, M | 1 |
| Slominska, E | 1 |
| Di Florio, E | 1 |
| Bracco, A | 1 |
| Mancini, A | 1 |
| Stassi, G | 1 |
| Patti, M | 1 |
| Giovannoni, R | 1 |
| Froio, A | 1 |
| Simeone, F | 1 |
| Forni, M | 1 |
| Bacci, ML | 1 |
| D'Alise, G | 1 |
| Cozzi, E | 1 |
| Yacoub, MH | 1 |
| Calise, F | 1 |
| Mann, BE | 1 |
| Foresti, R | 2 |
| Toyokawa, H | 1 |
| Abe, M | 1 |
| Kiyomoto, T | 1 |
| Nakahira, K | 1 |
| Choi, AM | 1 |
| Nalesnik, MA | 1 |
| Thomson, AW | 1 |
| Murase, N | 1 |
| Varadi, J | 1 |
| Szabo, G | 1 |
| Mei, DS | 1 |
| Du, YA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 2 Multi-center, Randomized, Double-blind, Comparator-Controlled Dose Finding Study to Evaluate MP4CO for the Acute Treatment of Vaso-occlusive Crises in Subjects With Sickle Cell Disease[NCT01925001] | Phase 2 | 0 participants (Actual) | Interventional | 2013-10-31 | Withdrawn (stopped due to Sangart ceased operations) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for carbon monoxide and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Role of Hydrogen Sulfide in Myocardial Ischemia-Reperfusion Injury.
Topics: Animals; Carbon Monoxide; Cardiovascular System; Cell Death; Gasotransmitters; Humans; Hydrogen Sulf | 2021 |
Endogenous Cardioprotective Agents: Role in Pre and Postconditioning.
Topics: Animals; Carbon Monoxide; Cardiotonic Agents; Gasotransmitters; Humans; Hydrogen Sulfide; Ischemic P | 2015 |
Pursuing enigmas on ischemic heart disease and sudden cardiac death.
Topics: Animals; Ankyrins; Calcium; Calpain; Carbon Monoxide; Carrier Proteins; Central Nervous System Stimu | 2009 |
[Trigger mechanism of adaptive phenomenon of ischemic heart postconditioning].
Topics: Adaptation, Physiological; Analgesics, Opioid; Animals; Biological Factors; Carbon Monoxide; Heart; | 2012 |
Therapeutic applications of carbon monoxide-releasing molecules.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Boranes; Carbon Monoxide; Carbonates; Heme Oxygen | 2005 |
25 other studies available for carbon monoxide and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Isoflurane and low-level carbon monoxide exposures increase expression of pro-survival miRNA in neonatal mouse heart.
Topics: Animals; Animals, Newborn; Apoptosis; Carbon Monoxide; Gene Expression; Heart; Isoflurane; Mice, Inb | 2021 |
Carbon Monoxide-Saturated Polymerized Placenta Hemoglobin Optimizes Mitochondrial Function and Protects Heart Against Ischemia-Reperfusion Injury.
Topics: Animals; Carbon Monoxide; Female; Hemoglobins; Humans; Insulin; Male; Mitochondria, Heart; Myocardia | 2021 |
Carbon Monoxide Releasing Molecule A1 Reduces Myocardial Damage After Acute Myocardial Infarction in a Porcine Model.
Topics: Animals; Apoptosis; Biomarkers; Boranes; Carbon Monoxide; Carbonates; Cardiovascular Agents; Caspase | 2021 |
Evaluating the effects of carbon monoxide releasing molecule-2 against myocardial ischemia-reperfusion injury in ovariectomized female rats.
Topics: Animals; Carbon Monoxide; Cardiotonic Agents; Female; Hemodynamics; Membrane Potential, Mitochondria | 2021 |
[Protective effects of endogenous carbon monoxide against myocardial ischemia-reperfusion injury in rats].
Topics: Animals; Carbon Monoxide; Creatine Kinase; Cyclic GMP; Heart; L-Lactate Dehydrogenase; Myocardial Re | 2018 |
Beneficial effect of prolonged heme oxygenase 1 activation in a rat model of chronic heart failure.
Topics: Animals; Apoptosis; Biomarkers; Carbon Monoxide; Disease Models, Animal; DNA Damage; Enzyme Activati | 2013 |
Carbon monoxide increases inducible NOS expression that mediates CO-induced myocardial damage during ischemia-reperfusion.
Topics: Air Pollutants; Animals; Antioxidants; Carbon Monoxide; Disease Models, Animal; Enzyme Inhibitors; E | 2015 |
CO-MP4, a polyethylene glycol-conjugated haemoglobin derivative and carbon monoxide carrier that reduces myocardial infarct size in rats.
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Drug Stability; Erythrocytes; Hemoglobins; Male; M | 2008 |
Role of heme oxygenase-1 in the cardioprotective effects of erythropoietin during myocardial ischemia and reperfusion.
Topics: Animals; Animals, Newborn; Apoptosis; Carbon Monoxide; Cardiotonic Agents; Caspase 3; Caspase 9; Cel | 2009 |
[Interaction between endogenous cystathionine synthase/hydrogen sulfide and heme oxygenase-1/carbon monoxide systems during myocardial ischemic-reperfusion: experiment with rats].
Topics: Animals; Carbon Monoxide; Cystathionine beta-Synthase; Disease Models, Animal; Heme Oxygenase (Decyc | 2008 |
Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both.
Topics: Administration, Inhalation; Animals; Apoptosis; Blotting, Western; Carbon Monoxide; Cold Ischemia; D | 2010 |
Simulated urban carbon monoxide air pollution exacerbates rat heart ischemia-reperfusion injury.
Topics: Air Pollutants; Air Pollution; Animals; Antioxidants; Arrhythmias, Cardiac; Calcium; Carbon Monoxide | 2010 |
Postischemic cardiac recovery in heme oxygenase-1 transgenic ischemic/reperfused mouse myocardium.
Topics: Animals; Calcium; Carbon Monoxide; Chromatography, Gas; Heart Function Tests; Heme Oxygenase-1; Male | 2011 |
Exogenous carbon monoxide does not affect cell membrane energy availability assessed by sarcolemmal calcium fluxes during myocardial ischaemia-reperfusion in the pig.
Topics: Animals; Calcium; Carbon Monoxide; Cell Membrane; Coronary Occlusion; Energy Metabolism; Glucose; Is | 2011 |
Re: Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both.
Topics: Administration, Inhalation; Animals; Apoptosis; Carbon Monoxide; Cold Ischemia; Drug Therapy, Combin | 2010 |
Moderate exercise prevents impaired Ca2+ handling in heart of CO-exposed rat: implication for sensitivity to ischemia-reperfusion.
Topics: Air Pollutants; Animals; Antioxidants; Calcium Signaling; Carbon Monoxide; Catalase; Cell Death; Glu | 2010 |
Carbon monoxide induces a late preconditioning-mimetic cardioprotective and antiapoptotic milieu in the myocardium.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carbon Monoxide; Cyclooxygenase 2; Heme Oxygenase | 2012 |
Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice.
Topics: Animals; Biomarkers; Blood Substitutes; Carbon Monoxide; Diabetes Complications; Energy Metabolism; | 2013 |
Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic/reperfused mouse myocardium.
Topics: Animals; Carbon Monoxide; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Memb | 2003 |
Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivo.
Topics: Animals; Body Temperature; Carbon Monoxide; Carboxyhemoglobin; Cardiotonic Agents; Drug Administrati | 2004 |
Heme oxygenase-1-derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury.
Topics: Animals; Apoptosis; Carbon Monoxide; Heart Transplantation; Heme Oxygenase (Decyclizing); Heme Oxyge | 2004 |
Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apoptosis; Carbon M | 2004 |
Heart allograft protection with low-dose carbon monoxide inhalation: effects on inflammatory mediators and alloreactive T-cell responses.
Topics: Administration, Inhalation; Animals; Base Sequence; Carbon Monoxide; Cytokines; DNA; Graft Survival; | 2006 |
Beneficial effects of carbon monoxide-releasing molecules on post-ischemic myocardial recovery.
Topics: Animals; Calcium; Carbon Monoxide; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart; Hear | 2007 |
[Cardioprotection and mechanisms of exogenous carbon monoxide releaser CORM-2 against ischemia/reperfusion injury in isolated rat hearts].
Topics: Animals; Carbon Monoxide; Cardiotonic Agents; Enzyme Inhibitors; In Vitro Techniques; Male; Myocardi | 2007 |