Page last updated: 2024-10-16

carbon monoxide and Hyperoxia

carbon monoxide has been researched along with Hyperoxia in 22 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Hyperoxia: An abnormal increase in the amount of oxygen in the tissues and organs.

Research Excerpts

ExcerptRelevanceReference
" Alternative experimental strategies to reduce oxygen delivery, including breathing carbon monoxide (600 ppm in air) or severe anemia, can reverse neurological disease."3.91Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation. ( Ast, T; Brepoels, K; Carmeliet, P; Galkin, A; Goldberger, O; Ichinose, F; Jain, IH; Marutani, E; Mootha, VK; Schleifer, G; Schoonjans, L; Stepanova, A; Wang, H; Wojtkiewicz, GR; Zapol, WM; Zazzeron, L, 2019)
" Hypoxia or endotoxin application did not exert any effect, whilst pure oxygen inhalation reduced deuterium oxidation."3.81The Evaluation and Quantitation of Dihydrogen Metabolism Using Deuterium Isotope in Rats. ( Galkin, A; Hyspler, R; Schierbeek, H; Ticha, A; Zadak, Z, 2015)
" We hypothesized that heme oxygenase (HO-1) and its byproduct carbon monoxide (CO), which are thought to be cytoprotective against redox stress, mitigate lung injury and alveolar simplification in hyperoxia-exposed neonatal mice, a model of BPD."3.80Suppression of inflammatory cell trafficking and alveolar simplification by the heme oxygenase-1 product carbon monoxide. ( Alghanem, H; Anyanwu, AC; Bentley, JK; Goldsmith, AM; Hershenson, MB; Malas, O; Pinsky, DJ; Popova, AP, 2014)
"The effects of hyperoxia (induced by host carbogen [95% oxygen/5% carbon dioxide breathing] and hypoxia (induced by host carbon monoxide [CO at 660 ppm] breathing) were compared by using noninvasive magnetic resonance (MR) methods to gain simultaneous information on blood flow/oxygenation and the bioenergetic status of rat Morris H9618a hepatomas."3.70Response of hepatoma 9618a and normal liver to host carbogen and carbon monoxide breathing. ( Griffiths, JR; Robinson, SP; Rodrigues, LM; Stubbs, M, 1999)
"During CO hypoxemia (1,700 ppm in air), VT as well as total DI and total DE decreased because of a large reduction in inspiratory and expiratory time elicited by tachypneic breathing."1.29Effects of hypercapnia and hypoxia on inspiratory and expiratory diaphragmatic activity in conscious cats. ( Bonora, M; Boule, M, 1994)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's6 (27.27)18.2507
2000's6 (27.27)29.6817
2010's9 (40.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jain, IH1
Zazzeron, L1
Goldberger, O1
Marutani, E1
Wojtkiewicz, GR1
Ast, T1
Wang, H1
Schleifer, G1
Stepanova, A1
Brepoels, K1
Schoonjans, L1
Carmeliet, P1
Galkin, A2
Ichinose, F1
Zapol, WM1
Mootha, VK1
van Ooij, PJ1
van Hulst, RA1
Houtkooper, A1
Sterk, PJ1
Anyanwu, AC1
Bentley, JK1
Popova, AP1
Malas, O1
Alghanem, H1
Goldsmith, AM1
Hershenson, MB1
Pinsky, DJ1
Ahlfeld, SK1
Gao, Y1
Conway, SJ1
Tepper, RS1
Hyspler, R1
Ticha, A1
Schierbeek, H1
Zadak, Z1
Tranquilli, AL1
Landi, B1
LILIENTHAL, JL1
RILEY, RL1
Tzaneva, V1
Bailey, S1
Perry, SF1
Lee, SJ1
Ryter, SW2
Xu, JF1
Nakahira, K2
Kim, HP2
Choi, AM4
Kim, YS1
Faller, S1
Hoetzel, A1
González-Alonso, J1
Olsen, DB1
Saltin, B1
Otterbein, LE3
Otterbein, SL1
Ifedigbo, E1
Liu, F1
Morse, DE1
Fearns, C1
Ulevitch, RJ1
Knickelbein, R1
Flavell, RA1
Molénat, F1
Boussuges, A1
Grandfond, A1
Rostain, JC1
Sainty, JM1
Robinet, C1
Galland, F1
Meliet, JL1
Zhang, X1
Shan, P1
Jiang, G1
Zhang, SS1
Fu, XY1
Lee, PJ1
Wang, X1
Wang, Y1
Thorsen, E1
Kambestad, BK1
Skrupskiĭ, VA1
Stepanov, VE1
Shulagin, IuA1
Bonora, M1
Boule, M1
Nordsmark, M1
Maxwell, RJ1
Horsman, MR1
Bentzen, SM1
Overgaard, J1
Mantell, LL1
Robinson, SP1
Rodrigues, LM1
Griffiths, JR1
Stubbs, M1
Clayton, CE1
Carraway, MS1
Suliman, HB1
Thalmann, ED1
Thalmann, KN1
Schmechel, DE1
Piantadosi, CA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Blood Carboxyhemoglobin Levels on Total Antioxidant (Tas), Total Oxidant(Tos), Hypoxia Inducible Factor-1a (hif1a) During Low-flow and Normal-flow Anesthesia[NCT05661045]130 participants (Anticipated)Observational2023-01-02Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for carbon monoxide and Hyperoxia

ArticleYear
Carbon monoxide in acute lung injury.
    Current pharmaceutical biotechnology, 2012, Volume: 13, Issue:6

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Carbon Monoxide; Humans; Hyperoxia; Lung Trans

2012

Trials

3 trials available for carbon monoxide and Hyperoxia

ArticleYear
Nitric oxide and carbon monoxide diffusing capacity after a 1-h oxygen dive to 9 m of sea water.
    Clinical physiology and functional imaging, 2014, Volume: 34, Issue:3

    Topics: Administration, Inhalation; Adult; Biomarkers; Carbon Monoxide; Cross-Over Studies; Diving; Double-B

2014
Erythrocyte and the regulation of human skeletal muscle blood flow and oxygen delivery: role of circulating ATP.
    Circulation research, 2002, Nov-29, Volume: 91, Issue:11

    Topics: Adenosine Triphosphate; Administration, Inhalation; Adult; Blood Flow Velocity; Carbon Monoxide; Car

2002
Haemodynamic effects of hyperbaric hyperoxia in healthy volunteers: an echocardiographic and Doppler study.
    Clinical science (London, England : 1979), 2004, Volume: 106, Issue:4

    Topics: Adult; Analysis of Variance; Carbon Monoxide; Diving; Echocardiography, Doppler; Follow-Up Studies;

2004

Other Studies

18 other studies available for carbon monoxide and Hyperoxia

ArticleYear
Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation.
    Cell metabolism, 2019, 10-01, Volume: 30, Issue:4

    Topics: Anemia; Animals; Basic Helix-Loop-Helix Transcription Factors; Brain; Carbon Monoxide; Disease Model

2019
Suppression of inflammatory cell trafficking and alveolar simplification by the heme oxygenase-1 product carbon monoxide.
    American journal of physiology. Lung cellular and molecular physiology, 2014, Apr-15, Volume: 306, Issue:8

    Topics: Animals; Animals, Newborn; Antimetabolites; Blotting, Western; Carbon Monoxide; Cells, Cultured; Che

2014
Relationship of structural to functional impairment during alveolar-capillary membrane development.
    The American journal of pathology, 2015, Volume: 185, Issue:4

    Topics: Animals; Animals, Newborn; Capillaries; Carbon Monoxide; Diffusion; Hyperoxia; Membranes; Mice, Inbr

2015
The Evaluation and Quantitation of Dihydrogen Metabolism Using Deuterium Isotope in Rats.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Animals; Antioxidants; Ascitic Fluid; Body Water; Carbon Monoxide; Cattle; Deuterium; Drug Evaluatio

2015
The origin of pre-eclampsia: from decidual "hyperoxia" to late hypoxia.
    Medical hypotheses, 2010, Volume: 75, Issue:1

    Topics: Carbon Monoxide; Female; Humans; Hyperoxia; Hypoxia; Leptin; Oxidative Stress; Pre-Eclampsia; Pregna

2010
The relationships between carbon monoxide, oxygen and hemoglobin in the blood of man at altitude.
    The American journal of physiology, 1946, Volume: 145

    Topics: Altitude; Biochemical Phenomena; Carbon Monoxide; Hemoglobins; Humans; Hyperoxia; Oxygen

1946
The interactive effects of hypoxemia, hyperoxia, and temperature on the gill morphology of goldfish (Carassius auratus).
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:6

    Topics: Adaptation, Physiological; Animals; Carbon Monoxide; Gills; Goldfish; Hemoglobins; Hyperoxia; Hypoxi

2011
Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation.
    American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:4

    Topics: Administration, Inhalation; Animals; Antioxidants; Autophagy; Carbon Monoxide; Cell Line, Tumor; Cyt

2011
MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury.
    The American journal of pathology, 2003, Volume: 163, Issue:6

    Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Cells, Cultured; Cytokines; Cytoprotection; Enzyme Acti

2003
Endothelial STAT3 is essential for the protective effects of HO-1 in oxidant-induced lung injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:12

    Topics: Animals; Carbon Monoxide; Endothelial Cells; Heme Oxygenase-1; Humans; Hyperoxia; Lung; Lung Disease

2006
Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation.
    The Journal of biological chemistry, 2007, Jan-19, Volume: 282, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carbon Monoxide; Endothelial Cells; E

2007
Persistent small-airways dysfunction after exposure to hyperoxia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:4

    Topics: Adult; Airway Obstruction; Analysis of Variance; Carbon Monoxide; Decompression; Diving; Follow-Up S

1995
[Monitoring of endogenous carbon monoxide elimination in exhaled air of rats in hyperoxia].
    Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine, 1995, Volume: 29, Issue:1

    Topics: Animals; Breath Tests; Carbon Dioxide; Carbon Monoxide; Hyperoxia; Monitoring, Physiologic; Rats; Sp

1995
Effects of hypercapnia and hypoxia on inspiratory and expiratory diaphragmatic activity in conscious cats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:4

    Topics: Animals; Carbon Dioxide; Carbon Monoxide; Carotid Body; Cats; Conscious Sedation; Denervation; Diaph

1994
The effect of hypoxia and hyperoxia on nucleoside triphosphate/inorganic phosphate, pO2 and radiation response in an experimental tumour model.
    British journal of cancer, 1997, Volume: 76, Issue:11

    Topics: Administration, Inhalation; Animals; Carbon Dioxide; Carbon Monoxide; Cell Division; Energy Metaboli

1997
Carbon monoxide provides protection against hyperoxic lung injury.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Heme Oxygenase (Decyclizing); Hem

1999
Response of hepatoma 9618a and normal liver to host carbogen and carbon monoxide breathing.
    Neoplasia (New York, N.Y.), 1999, Volume: 1, Issue:6

    Topics: Animals; Carbon Dioxide; Carbon Monoxide; Hyperoxia; Hypoxia; Liver; Liver Neoplasms, Experimental;

1999
Inhaled carbon monoxide and hyperoxic lung injury in rats.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:4

    Topics: Animals; Blood Gas Analysis; Blotting, Western; Brain Diseases; Carbon Monoxide; Carboxyhemoglobin;

2001