Page last updated: 2024-10-16

carbon monoxide and Heroin Abuse

carbon monoxide has been researched along with Heroin Abuse in 3 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Research Excerpts

ExcerptRelevanceReference
" Smoking cessation rates in methadone-maintained smokers are low and novel treatment strategies are required."9.17Varenicline for smoking cessation among methadone-maintained smokers: a randomized clinical trial. ( Anderson, BJ; Audet, D; Caviness, CM; Kurth, ME; Olson, J; Stein, MD, 2013)
" Smoking cessation rates in methadone-maintained smokers are low and novel treatment strategies are required."5.17Varenicline for smoking cessation among methadone-maintained smokers: a randomized clinical trial. ( Anderson, BJ; Audet, D; Caviness, CM; Kurth, ME; Olson, J; Stein, MD, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stein, MD1
Caviness, CM1
Kurth, ME1
Audet, D1
Olson, J1
Anderson, BJ1
Spiga, R1
Schmitz, J1
Day, J1
Haug, NA1
Stitzer, ML1
Svikis, DS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Varenicline Versus Nicotine Replacement for Methadone-Maintained Smokers[NCT00790569]315 participants (Actual)Interventional2008-09-30Completed
An Innovative Digital Smoking Cessation Intervention for Low-Income Adults With Substance Use Disorder[NCT04419922]100 participants (Actual)Observational2020-04-02Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Carbon Monoxide (CO)-Confirmed 7-day Abstinence

Number of participants reporting 7-day abstinence at 6-months, confirmed with CO measurement. (NCT00790569)
Timeframe: 6-Months

Interventionparticipants (Number)
Arm I5
Arm II1
Arm III11

Change in Cigarettes Per Day

Change in mean cigarettes per day (NCT00790569)
Timeframe: 6-Months

Interventioncigarettes/day (Mean)
Arm I-8.7
Arm II-8.5
Arm III-7.8

Change in Smoking Urges

Smoking urges was measured on a 0 (not at all) - 100 (strongest feeling possible) scale. Higher values represent greater urge to smoke. Change in smoking urges was calculated as Follow-up score (6 month) - Baseline Score. (NCT00790569)
Timeframe: 6 months

Interventionunits on a scale (Mean)
Arm I-29.971
Arm II-25.015
Arm III-24.177

CO-confirmed 7-day Abstinence

Number of participants reporting 7-day abstinence at 12-months, confirmed with CO measurement. (NCT00790569)
Timeframe: 12 Months

Interventionparticipants (Number)
Arm I4
Arm II1
Arm III8

Rates of Smoking Cessation Continuous From First Quit Day to 6 Months

Number of participants who self-reported continuous abstinence from their initial quit day (study day 14) to 6 Months (NCT00790569)
Timeframe: 6-Months

Interventionparticipants (Number)
Arm I2
Arm II0
Arm III2

Reinforcing Effects of Smoking

Reinforcing effects of smoking was measured using the modified version of the Cigarette Evaluation Questionnaire. Participants were asked to indicate on a 12-item scale how smoking made them feel in the prior 30 days on a scale from 1 (Not at all) to 7 (Extremely). Higher values indicated that smoking was a more positive experience for 10 of 12 items. Two items were reverse coded. Change in reinforcing effects of smoking was calculated as Follow-up score (6 month) - Baseline Score. (NCT00790569)
Timeframe: 6 months

Interventionunits on a scale (Mean)
Arm I-1.005
Arm II-.683
Arm III-.761

Self- Reported 7-day Abstinence

Number of participants with self-reported, 7-day abstinence at 6-months (NCT00790569)
Timeframe: 6 Months

Interventionparticipants (Number)
Arm I11
Arm II3
Arm III16

Self-reported 7-day Abstinence

Number of participants with self-reported 7-day abstinence at 12-months (NCT00790569)
Timeframe: 12 Months

Interventionparticipants (Number)
Arm I4
Arm II3
Arm III11

Withdrawal Symptoms

Withdrawal Symptoms were measured using a modified version of the Minnesota Behavior Rating Scale. The scale asked subjects to rate their smoking withdrawal symptoms over the previous 24 hours on a scale from 0 (none) to 4 (severe). Higher values indicate more severe withdrawal symptoms. Change in withdrawal symptoms was calculated as Follow-up score (6 month) - Baseline Score. (NCT00790569)
Timeframe: 6 months

Interventionunits on a scale (Mean)
Arm I-.222
Arm II-.163
Arm III-.113

Trials

2 trials available for carbon monoxide and Heroin Abuse

ArticleYear
Varenicline for smoking cessation among methadone-maintained smokers: a randomized clinical trial.
    Drug and alcohol dependence, 2013, Dec-01, Volume: 133, Issue:2

    Topics: Adult; Benzazepines; Carbon Monoxide; Female; Follow-Up Studies; Guideline Adherence; Heroin Depende

2013
Effects of nicotine on methadone self-administration in humans.
    Drug and alcohol dependence, 1998, Apr-01, Volume: 50, Issue:2

    Topics: Adult; Analysis of Variance; Behavior, Addictive; Carbon Monoxide; Drug Interactions; Female; Heroin

1998

Other Studies

1 other study available for carbon monoxide and Heroin Abuse

ArticleYear
Smoking during pregnancy and intention to quit: a profile of methadone-maintained women.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2001, Volume: 3, Issue:4

    Topics: Adult; Attitude to Health; Carbon Monoxide; Cotinine; Ethnicity; Female; Follow-Up Studies; Heroin D

2001