Page last updated: 2024-10-16

carbon monoxide and Hematologic Diseases

carbon monoxide has been researched along with Hematologic Diseases in 11 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Hematologic Diseases: Disorders of the blood and blood forming tissues.

Research Excerpts

ExcerptRelevanceReference
" In multivariate analysis, chronic graft-versus-host disease (relative risk, 16) and pretransplantation diffusion capacity for carbon monoxide or forced expiratory volume in the first second <80% predicted were independently associated with a late decrease in PF from baseline (relative risk, 7)."3.73Chronic GVHD and pretransplantation abnormalities in pulmonary function are the main determinants predicting worsening pulmonary function in long-term survivors after stem cell transplantation. ( Barrett, AJ; Childs, R; Karimpour, S; Mielke, S; Montero, A; Rezvani, K; Savani, BN; Shenoy, A; Singh, A; Srinivasan, R, 2006)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Le Bourgeois, A1
Malard, F1
Chevallier, P1
Urbistandoy, G1
Guillaume, T1
Delaunay, J1
Peterlin, P1
Lemarchand, P1
Germaud, P1
Mohty, M1
Moreau, P1
Chambellan, A1
Franco, RS1
ENGSTEDT, L1
OSKI, FA1
ALTMAN, AA1
WALLER, HD1
STAHL, W1
PALMACARLOS, AG1
PALMACARLOS, ML1
DUCLASOARES, A1
Savani, BN1
Montero, A1
Srinivasan, R1
Singh, A1
Shenoy, A1
Mielke, S1
Rezvani, K1
Karimpour, S1
Childs, R1
Barrett, AJ1
Winchell, HS1
Bratteby, LE1
Karendal, B1
Wadman, B1
Gydell, K1
Stupfel, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Trial of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for Treatment of Bronchiolitis Obliterans Syndrome[NCT01287078]Phase 225 participants (Actual)Interventional2011-01-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Disease Progression at Baseline With Decline in FEV1 Greater Than 10%

Participants with progressive disease at baseline with decline in FEV1 greater than 10% (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients2
Inhaled Cyclosporine in Lung Transplant Recipients0

Disease Progression at Baseline With Stablization of FEV1

Participants with progressive disease at baseline with stablization of FEV1 (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients2
Inhaled Cyclosporine in Lung Transplant Recipients0

Disease Stability at Baseline With Stablization in FEV1 and Greater Than 25% Decline in Systemic Immunosuppression

Participants with stable disease at baseline with stablization in FEV1 and greater than 25% decline in systemic immunosuppression (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients3
Inhaled Cyclosporine in Lung Transplant Recipients0

Overall Non-response to Treatment

Participants who did not respond to treatment with cyclosporine inhalation solution (CIS) (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients7
Inhaled Cyclosporine in Lung Transplant Recipients2

Overall Response to Treatment Based on Positive Response to Cyclosporine Inhalation Solution (CIS)

Participants who responded to treatment with cyclosporine inhalation solution (CIS) (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients9
Inhaled Cyclosporine in Lung Transplant Recipients0

Stable Disease at Baseline With Stablization of FEV1 and no Change or Increase in Systemic Immunosuppresion

Participants with stable disease at baseline with stablization of FEV1 and no change or increase in systemic immunosuppresion (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients4
Inhaled Cyclosporine in Lung Transplant Recipients2

Stable or Progressive Disease at Baseline With Greater Than 20% of Decline in FEV1

Participants with stable or progressive disease at baseline with greater than 20% of decline in FEV1 (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients1
Inhaled Cyclosporine in Lung Transplant Recipients0

Stable or Progressive Disease at Baseline With Improvement of FEV1

Participants with stable or progressive disease at baseline with improvement of FEV1 (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients4
Inhaled Cyclosporine in Lung Transplant Recipients0

Reviews

2 reviews available for carbon monoxide and Hematologic Diseases

ArticleYear
The measurement and importance of red cell survival.
    American journal of hematology, 2009, Volume: 84, Issue:2

    Topics: Anemia; Animals; Biotinylation; Breath Tests; Carbon Monoxide; Chromium Isotopes; Chromium Radioisot

2009
Quantitation of red cell and heme production and destruction using radioisotope kinetics.
    Progress in atomic medicine, 1968, Volume: 2

    Topics: Animals; Autoradiography; Blood Volume Determination; Carbon Isotopes; Carbon Monoxide; Cell Surviva

1968

Trials

1 trial available for carbon monoxide and Hematologic Diseases

ArticleYear
Impact of pre-transplant diffusion lung capacity for nitric oxide (DLNO) and of DLNO/pre-transplant diffusion lung capacity for carbon monoxide (DLNO/DLCO) ratio on pulmonary outcomes in adults receiving allogeneic stem cell transplantation for hematologi
    Bone marrow transplantation, 2016, Volume: 51, Issue:4

    Topics: Adult; Aged; Allografts; Carbon Monoxide; Female; Hematologic Diseases; Hematopoietic Stem Cell Tran

2016

Other Studies

8 other studies available for carbon monoxide and Hematologic Diseases

ArticleYear
Endogenous formation of carbon monoxide in hemolytic disease; with special regard to quantitative comparisons to other hemolytic indices.
    Acta medica Scandinavica. Supplementum, 1957, Volume: 332

    Topics: Carbon Monoxide; Cell Death; Hematologic Diseases; Hemoglobins; Hemolysis; Humans

1957
Carboxyhemoglobin levels in hemolytic disease of the newborn.
    The Journal of pediatrics, 1962, Volume: 61

    Topics: Carbon Monoxide; Carboxyhemoglobin; Erythroblastosis, Fetal; Fetus; Hematologic Diseases; Hemoglobin

1962
[THE VALUE OF TOTAL HEMOGLOBIN (HBT) DETERMINATION FOR THE EVALUATION OF THE COURSE OF HEMATOLOGIC DISEASES].
    Deutsche medizinische Wochenschrift (1946), 1963, Dec-06, Volume: 88

    Topics: Anemia; Anemia, Hypochromic; Anemia, Pernicious; Carbon Monoxide; Hematologic Diseases; Hemoglobinom

1963
[THE STUDY OF SERUM CO CONCENTRATION IN SOME HEMOPATHIES].
    Sangre, 1964, Volume: 10

    Topics: Anemia; Blood; Carbon Monoxide; Hematologic Diseases; Hemoglobinuria; Hemoglobinuria, Paroxysmal; Hu

1964
Chronic GVHD and pretransplantation abnormalities in pulmonary function are the main determinants predicting worsening pulmonary function in long-term survivors after stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Carbon Monoxide; Child; Chronic Disease; Comorbidity; Disease Progression; Female

2006
[Determination of THb with CO- respectively 51 Cr-technic].
    Nordisk medicin, 1971, Volume: 86, Issue:49

    Topics: Carbon Monoxide; Chromium Isotopes; Erythrocytes; Hematologic Diseases; Hemoglobins; Humans

1971
Simplified method for determining carbon monoxide hemoglobin saturation in diagnosis of hemolytic disorders.
    Acta medica Scandinavica. Supplementum, 1966, Volume: 445

    Topics: Carbon Monoxide; Hematologic Diseases; Hemoglobins; Hemolysis; Humans; In Vitro Techniques; Oxygen;

1966
[The physiological stores of carbon monoxide in the body].
    La Presse medicale, 1970, Nov-07, Volume: 78, Issue:47

    Topics: Air Pollution; Body Composition; Carbon Monoxide; Hematologic Diseases; Hemoglobins; Humans; Methods

1970