carbon monoxide has been researched along with Heart Failure in 53 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to evaluate the pulmonary effects of amiodarone in patients with heart failure, in those with chronic obstructive pulmonary disease (COPD) and in those undergoing a surgical procedure." | 9.08 | Pulmonary effect of amiodarone in patients with heart failure. The Congestive Heart Failure-Survival Trial of Antiarrhythmic Therapy (CHF-STAT) Investigators (Veterans Affairs Cooperative Study No. 320). ( Deedwania, PC; Fisher, SG; Fletcher, RD; Rohatgi, P; Singh, BN; Singh, SN, 1997) |
| "The combined effects of carbon monoxide and low temperature on daily variation in hospital admissions for congestive heart failure (CHF) were examined for a 4-year period in Chicago, Illinois." | 7.70 | Carbon monoxide and hospital admissions for congestive heart failure: evidence of an increased effect at low temperatures. ( Morris, RD; Naumova, EN, 1998) |
| "We examined the role that ambient air pollution plays in exacerbating cardiac disease by relating daily fluctuations in admissions to 134 hospitals for congestive heart failure in the elderly to daily variations in ambient concentrations of carbon monoxide, nitrogen dioxide, sulfur dioxide, ozone, and the coefficient of haze in Canada's 10 largest cities for the 11-year period 1981-1991 inclusive." | 7.69 | Association between ambient carbon monoxide levels and hospitalizations for congestive heart failure in the elderly in 10 Canadian cities. ( Brook, JR; Burnett, RT; Dales, RE; Krewski, D; Raizenne, ME, 1997) |
| "Carbon monoxide (CO) is a gaseous neurotransmitter in the central nervous system that stimulates VP neuronal firing activity." | 5.43 | A Functional Coupling Between Carbon Monoxide and Nitric Oxide Contributes to Increased Vasopressin Neuronal Activity in Heart Failure rats. ( Biancardi, VC; Reis, WL; Stern, JE; Zhou, Y, 2016) |
| "The purpose of this study was to evaluate the pulmonary effects of amiodarone in patients with heart failure, in those with chronic obstructive pulmonary disease (COPD) and in those undergoing a surgical procedure." | 5.08 | Pulmonary effect of amiodarone in patients with heart failure. The Congestive Heart Failure-Survival Trial of Antiarrhythmic Therapy (CHF-STAT) Investigators (Veterans Affairs Cooperative Study No. 320). ( Deedwania, PC; Fisher, SG; Fletcher, RD; Rohatgi, P; Singh, BN; Singh, SN, 1997) |
| "Five databases were searched for studies investigating the association between daily increases in gaseous (carbon monoxide, sulphur dioxide, nitrogen dioxide, ozone) and particulate (diameter <2·5 μm [PM2·5] or <10 μm [PM10]) air pollutants, and heart failure hospitalisations or heart failure mortality." | 4.89 | Global association of air pollution and heart failure: a systematic review and meta-analysis. ( Donaldson, K; Hunter, AL; Langrish, JP; McAllister, DA; Mills, NL; Nair, H; Newby, DE; Shah, AS, 2013) |
| "The prognostic role of diffusing capacity of the lung for carbon monoxide (DLCO) in heart failure has not been thoroughly investigated." | 4.31 | Association between DLCO index and the severity of heart failure: a cross-sectional study. ( Bakhtiyari, M; Emami, S; Eskandari, M; Esmaili, S; Izadi, S; Khavandegar, A; Saleh, M; Yadollahzadeh, M, 2023) |
| "Carbon monoxide diffusion capacity (DLCO) is impaired in heart failure patients; however, its clinical impact has not been well investigated in the left ventricular assist device (LVAD) population." | 4.02 | Carbon Monoxide Diffusing Capacity Predicts Cardiac Readmission in Patients Undergoing Left Ventricular Assist Device Implantation in Japan. ( Amiya, E; Ando, M; Bujo, C; Endo, M; Hara, T; Hatano, M; Hosoya, Y; Imai, H; Ishida, J; Kagami, Y; Kimura, M; Kinoshita, O; Komuro, I; Maki, H; Minatsuki, S; Nemoto, M; Ono, M; Saito, A; Shimada, S; Tsuji, M, 2021) |
| "This study sought to investigate the prognostic importance of a low diffusion capacity of the lung for carbon monoxide (DLCO) in patients with a catheter-based diagnosis of pulmonary hypertension due to heart failure with preserved ejection fraction (PH-HFpEF)." | 3.83 | Diffusion Capacity and Mortality in Patients With Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction. ( Fuge, J; Hoeper, MM; Meyer, K; Olsson, KM; Rademacher, J; Welte, T, 2016) |
| "Using a time-stratified case-crossover design, over 400,000 myocardial infarction (MI) events from the Myocardial Ischaemia National Audit Project (MINAP) database, over 2 million CVD emergency hospital admissions and over 600,000 CVD deaths were linked with daily mean concentrations of carbon monoxide (CO), nitrogen dioxide (NO2), particulate matter less than 10 μm in aerodynamic diameter (PM10), particulate matter less than 2." | 3.80 | Short-term effects of air pollution on a range of cardiovascular events in England and Wales: case-crossover analysis of the MINAP database, hospital admissions and mortality. ( Armstrong, B; Bhaskaran, K; Hajat, S; Milojevic, A; Smeeth, L; Wilkinson, P, 2014) |
| "Heart failure (HF) is often associated with interstitial pulmonary edema and structural changes, resulting in thickening of the alveolar-capillary membrane and reductions in diffusing capacity of the lung for carbon monoxide (Dlco)." | 3.74 | Impaired pulmonary diffusing capacity and hypoxia in heart failure correlates with central sleep apnea severity. ( Kaye, DM; Krum, H; Naughton, MT; Szollosi, I; Thompson, BR, 2008) |
| "We hypothesized that inhalation of carbon monoxide (CO) (500 ppm), similar to that in tobacco smoke, disturbs the cardiovascular adaptation after myocardial infarction by increasing remodeling." | 3.73 | CO inhalation at dose corresponding to tobacco smoke worsens cardiac remodeling after experimental myocardial infarction in rats. ( Bonnet, P; Eder, V; Fauchier, L; Hyvelin, JM; Machet, MC; Mirza, A; Rochefort, GY, 2005) |
| "The combined effects of carbon monoxide and low temperature on daily variation in hospital admissions for congestive heart failure (CHF) were examined for a 4-year period in Chicago, Illinois." | 3.70 | Carbon monoxide and hospital admissions for congestive heart failure: evidence of an increased effect at low temperatures. ( Morris, RD; Naumova, EN, 1998) |
| "The pulmonary diffusing capacity for carbon monoxide (DLCO) is reduced in chronic heart failure and remains decreased after heart transplantation." | 3.70 | Lung membrane diffusing capacity, heart failure, and heart transplantation. ( Charloux, A; Epailly, E; Frans, A; Lampert, E; Lonsdorfer, J; Mettauer, B; Oswald, M; Piquard, F; Zhao, QM, 1999) |
| "Cardiac enlargement in chronic heart failure appears to be involved in causing restrictive lung pattern and a reduced alveolar volume that disturbs carbon monoxide diffusion." | 3.70 | Cardiomegaly as a possible cause of lung dysfunction in patients with heart failure. ( Agostoni, P; Bussotti, M; Cattadori, G; Guazzi, M; Marenzi, G; Palermo, P, 2000) |
| "Medicare hospital admissions data, ambient air pollution monitoring data, and meteorological data were used to create daily values of hospital admissions for congestive heart failure, maximum hourly temperature, and maximum hourly levels of carbon monoxide, nitrogen dioxide, sulfur dioxide, and ozone." | 3.69 | Ambient air pollution and hospitalization for congestive heart failure among elderly people in seven large US cities. ( Morris, RD; Munasinghe, RL; Naumova, EN, 1995) |
| "We examined the role that ambient air pollution plays in exacerbating cardiac disease by relating daily fluctuations in admissions to 134 hospitals for congestive heart failure in the elderly to daily variations in ambient concentrations of carbon monoxide, nitrogen dioxide, sulfur dioxide, ozone, and the coefficient of haze in Canada's 10 largest cities for the 11-year period 1981-1991 inclusive." | 3.69 | Association between ambient carbon monoxide levels and hospitalizations for congestive heart failure in the elderly in 10 Canadian cities. ( Brook, JR; Burnett, RT; Dales, RE; Krewski, D; Raizenne, ME, 1997) |
| "Carbon monoxide (CO) is a gaseous neurotransmitter in the central nervous system that stimulates VP neuronal firing activity." | 1.43 | A Functional Coupling Between Carbon Monoxide and Nitric Oxide Contributes to Increased Vasopressin Neuronal Activity in Heart Failure rats. ( Biancardi, VC; Reis, WL; Stern, JE; Zhou, Y, 2016) |
| "We examined whether ischemic heart disease (IHD) hospital admissions were associated with air pollutants in those with and without secondary diagnoses of arrhythmia (ARR) or congestive heart failure (CHF)." | 1.31 | Air pollution and hospital admissions for ischemic heart disease in persons with congestive heart failure or arrhythmia. ( Lugg, MM; Lurmann, F; Mann, JK; Quesenberry, CP; Segal, M; Shan, J; Tager, IB; Van Den Eeden, SK, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (7.55) | 18.7374 |
| 1990's | 9 (16.98) | 18.2507 |
| 2000's | 15 (28.30) | 29.6817 |
| 2010's | 16 (30.19) | 24.3611 |
| 2020's | 9 (16.98) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlgrim, C | 2 |
| Birkner, P | 2 |
| Seiler, F | 2 |
| Grundmann, S | 2 |
| Bode, C | 2 |
| Pottgiesser, T | 2 |
| Schoechlin, S | 1 |
| Izadi, S | 2 |
| Esmaili, S | 1 |
| Emami, S | 1 |
| Eskandari, M | 1 |
| Yadollahzadeh, M | 1 |
| Saleh, M | 1 |
| Khavandegar, A | 1 |
| Bakhtiyari, M | 1 |
| Mandić, M | 1 |
| Eriksson, LMJ | 1 |
| Melin, M | 1 |
| Skott, V | 1 |
| Sundblad, P | 1 |
| Gustafsson, T | 1 |
| Rullman, E | 1 |
| Magini, A | 2 |
| Contini, M | 4 |
| Spadafora, E | 1 |
| Apostolo, A | 4 |
| Salvioni, E | 3 |
| Barbieri, S | 2 |
| Sciomer, S | 1 |
| Andreini, D | 1 |
| Veglia, F | 1 |
| Zavorsky, GS | 2 |
| Agostoni, P | 9 |
| Tun, B | 1 |
| Ehrbar, R | 1 |
| Short, M | 1 |
| Cheng, S | 1 |
| Vasan, RS | 1 |
| Xanthakis, V | 1 |
| Tsuji, M | 1 |
| Amiya, E | 1 |
| Bujo, C | 1 |
| Hara, T | 1 |
| Saito, A | 1 |
| Minatsuki, S | 1 |
| Maki, H | 1 |
| Ishida, J | 1 |
| Hosoya, Y | 1 |
| Hatano, M | 1 |
| Imai, H | 1 |
| Nemoto, M | 1 |
| Kagami, Y | 1 |
| Endo, M | 1 |
| Kimura, M | 1 |
| Ando, M | 1 |
| Shimada, S | 1 |
| Kinoshita, O | 1 |
| Ono, M | 1 |
| Komuro, I | 1 |
| Lee, DW | 1 |
| Han, CW | 1 |
| Hong, YC | 1 |
| Oh, JM | 1 |
| Bae, HJ | 1 |
| Kim, S | 1 |
| Lim, YH | 1 |
| Ha, S | 1 |
| Männistö, T | 1 |
| Liu, D | 1 |
| Sherman, S | 1 |
| Ying, Q | 1 |
| Mendola, P | 1 |
| Paolillo, S | 1 |
| Vignati, C | 1 |
| Tarzia, V | 1 |
| Campodonico, J | 1 |
| Mapelli, M | 1 |
| Massetti, M | 1 |
| Bejko, J | 1 |
| Righini, F | 1 |
| Bottio, T | 1 |
| Bonini, N | 1 |
| Gugliandolo, P | 1 |
| Parati, G | 1 |
| Lombardi, C | 1 |
| Gerosa, G | 1 |
| Salvi, L | 1 |
| Alamanni, F | 1 |
| Nakamura, K | 1 |
| Kanzaki, H | 1 |
| Okada, A | 1 |
| Amaki, M | 1 |
| Takahama, H | 1 |
| Hasegawa, T | 1 |
| Sugano, Y | 1 |
| Yasuda, S | 1 |
| Anzai, T | 1 |
| Collino, M | 1 |
| Pini, A | 1 |
| Mugelli, N | 1 |
| Mastroianni, R | 1 |
| Bani, D | 1 |
| Fantozzi, R | 1 |
| Papucci, L | 1 |
| Fazi, M | 1 |
| Masini, E | 1 |
| Shah, AS | 1 |
| Langrish, JP | 1 |
| Nair, H | 1 |
| McAllister, DA | 1 |
| Hunter, AL | 1 |
| Donaldson, K | 1 |
| Newby, DE | 1 |
| Mills, NL | 1 |
| Hsieh, YL | 1 |
| Tsai, SS | 1 |
| Yang, CY | 1 |
| Pruett, WA | 1 |
| Husband, LD | 1 |
| Husband, G | 1 |
| Dakhlalla, M | 1 |
| Bellamy, K | 1 |
| Coleman, TG | 1 |
| Hester, RL | 1 |
| Milojevic, A | 1 |
| Wilkinson, P | 1 |
| Armstrong, B | 1 |
| Bhaskaran, K | 1 |
| Smeeth, L | 1 |
| Hajat, S | 1 |
| Gargiulo, P | 1 |
| Banfi, C | 1 |
| Ghilardi, S | 1 |
| Magrì, D | 1 |
| Giovannardi, M | 1 |
| Bonomi, A | 1 |
| Battaia, E | 1 |
| Filardi, PP | 1 |
| Tremoli, E | 1 |
| Hoeper, MM | 1 |
| Meyer, K | 1 |
| Rademacher, J | 1 |
| Fuge, J | 1 |
| Welte, T | 1 |
| Olsson, KM | 1 |
| Reis, WL | 1 |
| Biancardi, VC | 1 |
| Zhou, Y | 1 |
| Stern, JE | 1 |
| Olson, TP | 1 |
| Johnson, BD | 1 |
| Borlaug, BA | 1 |
| Reboul, C | 1 |
| Boissière, J | 1 |
| André, L | 1 |
| Meyer, G | 1 |
| Bideaux, P | 1 |
| Fouret, G | 1 |
| Feillet-Coudray, C | 1 |
| Obert, P | 2 |
| Lacampagne, A | 1 |
| Thireau, J | 1 |
| Cazorla, O | 1 |
| Richard, S | 1 |
| Lorenzi-Filho, G | 1 |
| Genta, PR | 1 |
| Sobański, P | 1 |
| Sinkiewicz, W | 1 |
| Kubica, J | 1 |
| Błazejewski, J | 1 |
| Bujak, R | 1 |
| Roulaud, M | 1 |
| Donal, E | 1 |
| Raud-Raynier, P | 1 |
| Denjean, A | 1 |
| de Bisschop, C | 1 |
| Wang, G | 1 |
| Hamid, T | 1 |
| Keith, RJ | 1 |
| Zhou, G | 1 |
| Partridge, CR | 1 |
| Xiang, X | 1 |
| Kingery, JR | 1 |
| Lewis, RK | 1 |
| Li, Q | 1 |
| Rokosh, DG | 1 |
| Ford, R | 1 |
| Spinale, FG | 1 |
| Riggs, DW | 1 |
| Srivastava, S | 1 |
| Bhatnagar, A | 1 |
| Bolli, R | 1 |
| Prabhu, SD | 1 |
| Lestar, M | 1 |
| Gunnarsson, L | 1 |
| Lagerstrand, L | 1 |
| Wiklund, P | 1 |
| Odeberg-Wernerman, S | 1 |
| Schultz, HD | 2 |
| Del Rio, R | 1 |
| Ding, Y | 2 |
| Marcus, NJ | 1 |
| Agostoni, PG | 1 |
| Bussotti, M | 3 |
| Palermo, P | 3 |
| Guazzi, M | 4 |
| Mann, JK | 1 |
| Tager, IB | 1 |
| Lurmann, F | 1 |
| Segal, M | 1 |
| Quesenberry, CP | 1 |
| Lugg, MM | 1 |
| Shan, J | 1 |
| Van Den Eeden, SK | 1 |
| Cattadori, G | 3 |
| Bianchi, M | 1 |
| Wasserman, K | 2 |
| Mirza, A | 1 |
| Eder, V | 2 |
| Rochefort, GY | 1 |
| Hyvelin, JM | 1 |
| Machet, MC | 1 |
| Fauchier, L | 2 |
| Bonnet, P | 2 |
| Witte, KK | 1 |
| Thackray, SD | 1 |
| Lindsay, KA | 1 |
| Cleland, JG | 1 |
| Clark, AL | 1 |
| Melin, A | 1 |
| Antier, D | 1 |
| Marenzi, G | 2 |
| Szollosi, I | 1 |
| Thompson, BR | 1 |
| Krum, H | 1 |
| Kaye, DM | 1 |
| Naughton, MT | 1 |
| Li, YL | 1 |
| Mifflin, SW | 1 |
| Schwartz, J | 1 |
| Morris, RD | 2 |
| Naumova, EN | 2 |
| Munasinghe, RL | 1 |
| Hexter, AC | 1 |
| Burnett, RT | 1 |
| Dales, RE | 1 |
| Brook, JR | 1 |
| Raizenne, ME | 1 |
| Krewski, D | 1 |
| Singh, SN | 1 |
| Fisher, SG | 1 |
| Deedwania, PC | 1 |
| Rohatgi, P | 1 |
| Singh, BN | 1 |
| Fletcher, RD | 1 |
| Mettauer, B | 1 |
| Lampert, E | 1 |
| Charloux, A | 1 |
| Zhao, QM | 1 |
| Epailly, E | 1 |
| Oswald, M | 1 |
| Frans, A | 1 |
| Piquard, F | 1 |
| Lonsdorfer, J | 1 |
| Guazzi, MD | 1 |
| Al-Rawas, OA | 1 |
| Carter, R | 1 |
| Stevenson, RD | 1 |
| Naik, SK | 1 |
| Wheatley, DJ | 1 |
| Dawber, TR | 1 |
| Thomas, HE | 1 |
| Beloev, I | 1 |
| Tsanev, B | 1 |
| Leikin, JB | 1 |
| Vogel, S | 1 |
| Gold, HK | 1 |
| Leinbach, RC | 1 |
| Sanders, CA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators: a Randomized Controlled Crossover Trial Among Healthy Young Adults[NCT02238028] | 28 participants (Actual) | Interventional | 2014-03-31 | Completed | |||
| Cardiopulmonary Interactions in Patients With Heart Failure (Kardio-pulmonale Interaktionen Bei Patienten Mit Linksherzerkrankungen)[NCT03317314] | 0 participants (Actual) | Observational | 2017-07-01 | Withdrawn (stopped due to Study was considered not useful and competing with another study in clinical context) | |||
| [NCT01927380] | 37 participants (Actual) | Observational | 2013-08-31 | Completed | |||
| Evaluation of Cardiac Functions in Robotic-assisted Prostatectomy Surgery Performed Under Deep Trendelenburg Position[NCT05685979] | 30 participants (Actual) | Observational | 2022-05-01 | Completed | |||
| Comparison of Two Different Anesthetic Techniques on Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position: A Prospective Randomized Clinical Trial[NCT03572517] | 65 participants (Actual) | Interventional | 2017-09-01 | Completed | |||
| Effect of Console Time on the Development of Acute Kidney Injury in Robotic-assisted Laparoscopic Prostatectomy[NCT06000098] | 50 participants (Anticipated) | Observational | 2023-09-25 | Not yet recruiting | |||
| Influence of ACE Genotype on Lung Diffusion at Rest and After Fluid Overload in Heart Failure Patients Treated With ACE-inhibitors[NCT00361127] | 100 participants (Actual) | Interventional | 2006-08-31 | Completed | |||
| Shunt Quantification in Atrial Septal Defect Using Inert Gas Rebreathing and Thoracic Bioimpedance: Comparison With the Gold Standard Method[NCT03437148] | 10 participants (Actual) | Interventional | 2018-07-18 | Terminated (stopped due to recruitment difficulty) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
At the end of each intervention, participants were asked to rest in a quiet room for half an hour. Peripheral venous blood samples were collected and centrifuged immediately. The serum were collected and stored at -80℃ within 30 minutes to minimize the in-vitro changes in biomarker proteins. Endothelin-1(ET-1) was using enzyme-linked immunosorbent assays. (NCT02238028)
Timeframe: Up to 24 hours
| Intervention | pg/ml (Geometric Mean) |
|---|---|
| Wear Respirator | 109.9 |
| Not Wear Respirator | 121.5 |
HRV is a quantitative health marker reflecting how the autonomic nervous system modulates the sinoatrial node in the heart and HRV has therefore been widely used to estimate cardiac autonomic function and control. Subjects were attached with Holter monitor on the 2nd day in each of the 48-hr intervention period.A total of 8 parameters of HRV were analyzed including 4 time-domain indices and 4 frequency-domain indices. Frequency domain methods assign bands of frequency and then count the number of NN intervals that match each band. The bands are typically high frequency (HF) from 0.15 to 0.4 Hz, low frequency (LF) from 0.04 to 0.15 Hz. Parasympathetic activity is a major contributor to the HF component. More problematic is the interpretation of the LF component, which was considered by some as a marker of sympathetic modulation but is now known to include both sympathetic and vagal influences. (NCT02238028)
Timeframe: Up to 24 hours
| Intervention | ratio (Geometric Mean) |
|---|---|
| Wear Respirator | 1.4 |
| Not Wear Respirator | 1.5 |
HRV is a quantitative health marker reflecting how the autonomic nervous system modulates the sinoatrial node in the heart and HRV has therefore been widely used to estimate cardiac autonomic function and control.A total of 8 parameters of HRV were analyzed including 4 time-domain indices and 4 frequency-domain indices. Subjects were attached with Holter monitor on the 2nd day in each of the 48-hr intervention period. Heart rate and heart automatic function indices including the proportion of successive normal NN intervals differing by more than 50 ms in the total number of NNs（pNN50） were automatically recorded during the intervention. (NCT02238028)
Timeframe: Up to 24 hours
| Intervention | percentage of ms (Geometric Mean) |
|---|---|
| Wear Respirator | 24.0 |
| Not Wear Respirator | 20.5 |
The blood pressure were measured by automatic blood pressure monitor during the intervention study. (NCT02238028)
Timeframe: up to 24 hours
| Intervention | mmHg (Mean) | |
|---|---|---|
| systolic blood pressure | diastolic blood pressure | |
| Not Wear Respirator | 109.0 | 70.8 |
| Wear Respirator | 107.3 | 70.0 |
At the end of each intervention, participants were asked to rest in a quiet room for half an hour. Peripheral venous blood samples were collected and centrifuged immediately. The serum were collected and stored at -80℃ within 30 minutes to minimize the in-vitro changes in biomarker proteins. Fibrinogen and von Willebrand factor(vWF) were measured by using the Millipore MILLIPLEX MAP human cytokine/chemokine kit (Millipore Corp., Billerica, Massachusetts) (NCT02238028)
Timeframe: Up to 24 hours
| Intervention | µg/ml (Geometric Mean) | |
|---|---|---|
| Fibrinogen | vWF | |
| Not Wear Respirator | 2.5 | 27.1 |
| Wear Respirator | 2.5 | 24.5 |
At the end of each intervention, participants were asked to rest in a quiet room for half an hour. Peripheral venous blood samples were collected and centrifuged immediately. The serum were collected and stored at -80℃ within 30 minutes to minimize the in-vitro changes in biomarker proteins. P- selectin,VCAM-1(vascular cell adhesion molecule-1) were measured by using the Millipore MILLIPLEX MAP human cytokine/chemokine kit (Millipore Corp., Billerica, Massachusetts) (NCT02238028)
Timeframe: Up to 24 hours
| Intervention | ng/ml (Geometric Mean) | |
|---|---|---|
| P-selectin | VCAM-1 | |
| Not Wear Respirator | 200.3 | 1808.0 |
| Wear Respirator | 164.0 | 1480.3 |
HRV is a quantitative health marker reflecting how the autonomic nervous system modulates the sinoatrial node in the heart and HRV has therefore been widely used to estimate cardiac autonomic function and control. Subjects were attached with Holter monitor on the 2nd day in each of the 48-hr intervention period.A total of 8 parameters of HRV were analyzed including 4 time-domain indices and 4 frequency-domain indices. Frequency domain methods assign bands of frequency and then count the number of NN intervals that match each band. The bands are typically high frequency (HF) from 0.15 to 0.4 Hz, low frequency (LF) from 0.04 to 0.15 Hz, and the very low frequency (VLF) from 0.0033 to 0.04 Hz. Parasympathetic activity is a major contributor to the HF component. More problematic is the interpretation of the LF component, which was considered by some as a marker of sympathetic modulation but is now known to include both sympathetic and vagal influences. (NCT02238028)
Timeframe: up to 24 hours
| Intervention | ms^2 (Geometric Mean) | ||
|---|---|---|---|
| low frequency(LF) power | high frequency(HF) power | very low frequency(VLF) power | |
| Not Wear Respirator | 838.5 | 416.6 | 1623.1 |
| Wear Respirator | 899.4 | 519.7 | 1684.6 |
HRV is a quantitative health marker reflecting how the autonomic nervous system modulates the sinoatrial node in the heart and HRV has therefore been widely used to estimate cardiac autonomic function and control.A total of 8 parameters of HRV were analyzed including 4 time-domain indices and 4 frequency-domain indices. Subjects were attached with Holter monitor on the 2nd day in each of the 48-hr intervention period. Heart rate and heart automatic function indices including the standard deviation of the normal-to-normal interval(SDNN),the standard deviation of the average NN intervals calculated over short periods(SDANN), the root mean square of the successive differences(rMSSD) were automatically recorded during the intervention. (NCT02238028)
Timeframe: Up to 24 hours
| Intervention | ms (Geometric Mean) | ||
|---|---|---|---|
| SDNN | SDANN | rMSSD | |
| All Study Participants | 177.5 | 160.7 | 49.0 |
2 reviews available for carbon monoxide and Heart Failure
| Article | Year |
|---|---|
Global association of air pollution and heart failure: a systematic review and meta-analysis.
Topics: Air Pollutants; Air Pollution; Carbon Monoxide; Epidemiologic Methods; Global Health; Heart Failure; | 2013 |
Role of neurotransmitter gases in the control of the carotid body in heart failure.
Topics: Animals; Carbon Monoxide; Carotid Body; Gases; Heart Failure; Humans; Hydrogen Sulfide; Neurotransmi | 2012 |
4 trials available for carbon monoxide and Heart Failure
| Article | Year |
|---|---|
Does lung diffusion impairment affect exercise capacity in patients with heart failure?
Topics: Blood Gas Analysis; Carbon Monoxide; Cardiac Output, Low; Chronic Disease; Exercise Test; Exercise T | 2002 |
Exercise-induced pulmonary edema in heart failure.
Topics: Aged; Blood Volume; Carbon Monoxide; Cell Membrane; Diagnostic Techniques, Cardiovascular; Diffusion | 2003 |
Pulmonary effect of amiodarone in patients with heart failure. The Congestive Heart Failure-Survival Trial of Antiarrhythmic Therapy (CHF-STAT) Investigators (Veterans Affairs Cooperative Study No. 320).
Topics: Aged; Amiodarone; Carbon Monoxide; Heart Failure; Humans; Lung; Lung Diseases, Obstructive; Prospect | 1997 |
Impeded alveolar-capillary gas transfer with saline infusion in heart failure.
Topics: Aldosterone; Blood Pressure; Blood Proteins; Blood-Air Barrier; Capillaries; Carbon Monoxide; Glucos | 1999 |
47 other studies available for carbon monoxide and Heart Failure
| Article | Year |
|---|---|
Estimated plasma volume status is a modest predictor of true plasma volume excess in compensated chronic heart failure patients.
Topics: Aged; Anthropometry; Area Under Curve; Carbon Monoxide; Cardiology; Chronic Disease; Cross-Sectional | 2021 |
Clinically unrecognized plasma volume expansion predicts long-term all-cause-mortality in chronic heart failure.
Topics: Carbon Monoxide; Chronic Disease; Diuretics; Female; Heart Failure; Humans; Pilot Projects; Plasma V | 2022 |
Association between DLCO index and the severity of heart failure: a cross-sectional study.
Topics: Adult; Aged; Carbon Monoxide; Cross-Sectional Studies; Female; Heart Failure; Humans; Male; Middle A | 2023 |
Increased maximal oxygen uptake after sprint-interval training is mediated by central haemodynamic factors as determined by right heart catheterization.
Topics: Carbon Monoxide; Cardiac Catheterization; Female; Heart Failure; Hemodynamics; Humans; Male; Oxygen; | 2023 |
Variability in pulmonary diffusing capacity in heart failure.
Topics: Aged; Carbon Monoxide; Female; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide; Pulmonary Dif | 2020 |
Association of Exhaled Carbon Monoxide With Ideal Cardiovascular Health, Circulating Biomarkers, and Incidence of Heart Failure in the Framingham Offspring Study.
Topics: Aged; Biomarkers; Blood Pressure; Carbon Monoxide; Exhalation; Female; Health Status; Heart Failure; | 2020 |
Carbon Monoxide Diffusing Capacity Predicts Cardiac Readmission in Patients Undergoing Left Ventricular Assist Device Implantation in Japan.
Topics: Carbon Monoxide; Heart Failure; Heart-Assist Devices; Humans; Japan; Patient Readmission; Respirator | 2021 |
Week to week variability of pulmonary capillary blood volume and alveolar membrane diffusing capacity in patients with heart failure.
Topics: Aged; Blood Volume; Capillaries; Carbon Monoxide; Female; Heart Failure; Humans; Male; Middle Aged; | 2021 |
Short-term exposure to air pollution and hospital admission for heart failure among older adults in metropolitan cities: a time-series study.
Topics: Air Pollutants; Air Pollution; Carbon Monoxide; Cities; Environmental Exposure; Heart Failure; Hospi | 2021 |
Air pollution and cardiovascular events at labor and delivery: a case-crossover analysis.
Topics: Adult; Air Pollutants; Air Pollution; Carbon Monoxide; Cardiovascular Diseases; Cross-Over Studies; | 2017 |
Comprehensive effects of left ventricular assist device speed changes on alveolar gas exchange, sleep ventilatory pattern, and exercise performance.
Topics: Aged; Carbon Monoxide; Equipment Design; Exercise; Female; Heart Failure; Heart-Assist Devices; Huma | 2018 |
Independent Prognostic Value of Pulmonary Diffusing Capacity in Nonsmoking Patients with Chronic Heart Failure.
Topics: Aged; Carbon Monoxide; Female; Follow-Up Studies; Heart Failure; Humans; Japan; Male; Middle Aged; N | 2019 |
Beneficial effect of prolonged heme oxygenase 1 activation in a rat model of chronic heart failure.
Topics: Animals; Apoptosis; Biomarkers; Carbon Monoxide; Disease Models, Animal; DNA Damage; Enzyme Activati | 2013 |
Fine particulate air pollution and hospital admissions for congestive heart failure: a case-crossover study in Taipei.
Topics: Air Pollutants; Air Pollution; Carbon Monoxide; Cities; Heart Failure; Hospitalization; Humans; Odds | 2013 |
A population model of integrative cardiovascular physiology.
Topics: Baroreflex; Blood Pressure; Blood Volume; Calibration; Carbon Monoxide; Cardiovascular Physiological | 2013 |
Short-term effects of air pollution on a range of cardiovascular events in England and Wales: case-crossover analysis of the MINAP database, hospital admissions and mortality.
Topics: Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Atrial Fibrillation; Carbon Monoxide; Cardio | 2014 |
Surfactant-derived proteins as markers of alveolar membrane damage in heart failure.
Topics: Aged; Biomarkers; Carbon Monoxide; Exercise Test; Female; Heart Failure; Humans; Male; Middle Aged; | 2014 |
Diffusion Capacity and Mortality in Patients With Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction.
Topics: Aged; Carbon Monoxide; Female; Heart Failure; Humans; Hypertension, Pulmonary; Kaplan-Meier Estimate | 2016 |
A Functional Coupling Between Carbon Monoxide and Nitric Oxide Contributes to Increased Vasopressin Neuronal Activity in Heart Failure rats.
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Heart Failure; Heme Oxygenase-1; Inhibitory Postsy | 2016 |
Impaired Pulmonary Diffusion in Heart Failure With Preserved Ejection Fraction.
Topics: Aged; Carbon Monoxide; Cardiac Output; Case-Control Studies; Echocardiography; Exercise Test; Exerci | 2016 |
Carbon monoxide pollution aggravates ischemic heart failure through oxidative stress pathway.
Topics: Air Pollutants; Animals; Calcium; Carbon Monoxide; Coronary Vessels; Disease Models, Animal; Electro | 2017 |
A new straw in the genesis of Cheyne-Stokes respiration.
Topics: Carbon Monoxide; Cheyne-Stokes Respiration; Heart Failure; Humans; Hypoxia; Pulmonary Gas Exchange; | 2008 |
The reliability of noninvasive cardiac output measurement using the inert gas rebreathing method in patients with advanced heart failure.
Topics: Breath Tests; Carbon Monoxide; Cardiac Output; Female; Heart Failure; Humans; Male; Middle Aged; Rep | 2008 |
Does exercise have deleterious consequences for the lungs of patients with chronic heart failure?
Topics: Aged; Analysis of Variance; Carbon Monoxide; Case-Control Studies; Chronic Disease; Contraindication | 2009 |
Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart.
Topics: Animals; Apoptosis; Carbon Monoxide; Cardiotonic Agents; Chronic Disease; Fibrosis; Gene Expression; | 2010 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Hemodynamic perturbations during robot-assisted laparoscopic radical prostatectomy in 45° Trendelenburg position.
Topics: Aged; Anesthesia, General; Carbon Monoxide; Echocardiography; Head-Down Tilt; Heart Failure; Hemodyn | 2011 |
Air pollution and hospital admissions for ischemic heart disease in persons with congestive heart failure or arrhythmia.
Topics: Aged; Air Pollutants; Arrhythmias, Cardiac; Carbon Monoxide; Epidemiologic Studies; Female; Heart Fa | 2002 |
CO inhalation at dose corresponding to tobacco smoke worsens cardiac remodeling after experimental myocardial infarction in rats.
Topics: Administration, Inhalation; Animals; Blood Pressure; Carbon Monoxide; Cardiomegaly; Echocardiography | 2005 |
Metabolic gas kinetics depend upon the level of exercise performed.
Topics: Blood Gas Analysis; Carbon Monoxide; Case-Control Studies; Exercise Test; Exercise Tolerance; Female | 2005 |
Direct implication of carbon monoxide in the development of heart failure in rats with cardiac hypertrophy subjected to air pollution.
Topics: Air Pollutants, Occupational; Air Pollution; Animals; Carbon Monoxide; Cardiomegaly; Echocardiograph | 2005 |
Noninvasive measurement of cardiac output during exercise by inert gas rebreathing technique: a new tool for heart failure evaluation.
Topics: Administration, Inhalation; Carbon Monoxide; Cardiac Output; Diagnostic Techniques, Cardiovascular; | 2005 |
Impaired pulmonary diffusing capacity and hypoxia in heart failure correlates with central sleep apnea severity.
Topics: Adult; Blood Gas Analysis; Carbon Monoxide; Cheyne-Stokes Respiration; Female; Heart Failure; Humans | 2008 |
Downregulation of carbon monoxide as well as nitric oxide contributes to peripheral chemoreflex hypersensitivity in heart failure rabbits.
Topics: Animals; Blood Pressure; Blotting, Western; Body Weight; Carbon Monoxide; Chemoreceptor Cells; Down- | 2008 |
NO and CO have got to GO for enhanced chemoreceptor sympathoexcitation in heart failure.
Topics: Animals; Carbon Monoxide; Chemoreceptor Cells; Heart Failure; Heme Oxygenase (Decyclizing); Kidney; | 2008 |
Is carbon monoxide a risk factor for hospital admission for heart failure?
Topics: Air Pollutants; Carbon Monoxide; Epidemiologic Methods; Heart Failure; Hospitalization; Humans; Risk | 1995 |
Ambient air pollution and hospitalization for congestive heart failure among elderly people in seven large US cities.
Topics: Age Distribution; Aged; Air Pollutants; Carbon Monoxide; Environmental Illness; Heart Failure; Hospi | 1995 |
Ambient carbon monoxide and hospitalizations for heart failure: earlier findings.
Topics: Air Pollutants; Carbon Monoxide; Heart Failure; Hospitalization; Humans; Los Angeles | 1996 |
Association between ambient carbon monoxide levels and hospitalizations for congestive heart failure in the elderly in 10 Canadian cities.
Topics: Aged; Air Pollutants; Canada; Carbon Monoxide; Cohort Studies; Dose-Response Relationship, Drug; Env | 1997 |
Carbon monoxide and hospital admissions for congestive heart failure: evidence of an increased effect at low temperatures.
Topics: Air Pollutants; Carbon Monoxide; Chicago; Cold Climate; Heart Failure; Hospitalization; Humans; Temp | 1998 |
Angiotensin-converting enzyme inhibition restores the diffusing capacity for carbon monoxide in patients with chronic heart failure by improving the molecular diffusion across the alveolar capillary membrane.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Blood Volume; Capillaries; Capillary | 1999 |
Lung membrane diffusing capacity, heart failure, and heart transplantation.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Carbon Monoxide; Case-Control Studies; Cytomegalovirus In | 1999 |
The alveolar-capillary membrane diffusing capacity and the pulmonary capillary blood volume in heart transplant candidates.
Topics: Adult; Capillaries; Carbon Monoxide; Case-Control Studies; Female; Heart Failure; Heart Transplantat | 2000 |
Cardiomegaly as a possible cause of lung dysfunction in patients with heart failure.
Topics: Aged; Blood Volume; Capillaries; Capillary Permeability; Carbon Monoxide; Cardiomegaly; Female; Forc | 2000 |
Smoking and heart disease: current thinking.
Topics: Adult; Aged; Carbon Monoxide; Cardiovascular Diseases; Cardiovascular System; Cerebrovascular Disord | 1979 |
[Disordered alveolar-capillary gas metabolism in the acute stage of myocardial infarct].
Topics: Acute Disease; Aged; Blood Gas Analysis; Capillaries; Carbon Monoxide; Female; Heart Failure; Humans | 1978 |
Carbon monoxide levels in cardiac patients in an urban emergency department.
Topics: Asthma; Carbon Monoxide; Carboxyhemoglobin; Coronary Disease; Heart Diseases; Heart Failure; Hemoglo | 1986 |
Use of sublingual nitroglycerin in congestive failure following acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Blood Pressure; Carbon Monoxide; Cardiac Output; Electrocardiog | 1972 |