Page last updated: 2024-10-16

carbon monoxide and Fibrosis

carbon monoxide has been researched along with Fibrosis in 21 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"We aimed to investigate the toxicity of carbon monoxide (CO) in rats with right ventricle (RV) remodeling induced by hypoxic pulmonary hypertension (PHT)."7.74Continuous inhalation of carbon monoxide induces right ventricle ischemia and dysfunction in rats with hypoxic pulmonary hypertension. ( Antier, D; Bonnet, P; Eder, V; Gautier, M; Hanton, G; Le Net, JL, 2007)
"Carbon monoxide (CO) is a critical endogenous signaling transducer with known anti-inflammatory and anti-fibrotic effects but its therapeutic potential in CLAD remains to be fully elucidated."5.91The mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation. ( Aoki, Y; Combs, MP; Fitzgerald, L; Lama, VN; Lyu, D; McLinden, AP; Mimura, T; Misumi, K; Osterholzer, JJ; Pinsky, DJ; Vittal, R; Walker, NM, 2023)
" Previously we developed a nano micellar CO donor SMA/CORM2 which shows superior bioavailability and therapeutic potential in many inflammatory disease models."5.72Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway. ( Cui, Y; Fang, J; Guo, C; Hu, W; Song, B; Xia, M; Xia, Z; Xu, D; Xue, Y; Zhang, C; Zhang, S, 2022)
"Tubulointerstitial fibrosis is a hallmark of chronic progressive kidney disease leading to end-stage renal failure."5.35Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction. ( Choi, ME; He, Y; Kim, SI; Kwak, JH; Lee, JY; Wang, L, 2008)
"We aimed to investigate the toxicity of carbon monoxide (CO) in rats with right ventricle (RV) remodeling induced by hypoxic pulmonary hypertension (PHT)."3.74Continuous inhalation of carbon monoxide induces right ventricle ischemia and dysfunction in rats with hypoxic pulmonary hypertension. ( Antier, D; Bonnet, P; Eder, V; Gautier, M; Hanton, G; Le Net, JL, 2007)
" Fifty-eight patients with normal liver function, 14 patients with chronic hepatitis, 28 patients with hepatic cirrhosis, and 4 patients with obstructive jaundice were studied by positron-emission tomography scan after the single breath inhalation of 20 mCi of high specific activity 15O-labeled carbon monoxide."3.69Quantitative measurement of human tissue hepatic blood volume by C15O inhalation with positron-emission tomography. ( Koyama, H; Masuyama, M; Oguro, A; Takahashi, T; Taniguchi, H, 1996)
"Carbon monoxide (CO) is a critical endogenous signaling transducer with known anti-inflammatory and anti-fibrotic effects but its therapeutic potential in CLAD remains to be fully elucidated."1.91The mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation. ( Aoki, Y; Combs, MP; Fitzgerald, L; Lama, VN; Lyu, D; McLinden, AP; Mimura, T; Misumi, K; Osterholzer, JJ; Pinsky, DJ; Vittal, R; Walker, NM, 2023)
" Previously we developed a nano micellar CO donor SMA/CORM2 which shows superior bioavailability and therapeutic potential in many inflammatory disease models."1.72Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway. ( Cui, Y; Fang, J; Guo, C; Hu, W; Song, B; Xia, M; Xia, Z; Xu, D; Xue, Y; Zhang, C; Zhang, S, 2022)
" The secondary aim was to explore the applicability of standard CO dosing methodologies to this patient population."1.56Application of the optimized carbon monoxide rebreathing method for the measurement of total haemoglobin mass in chronic liver disease. ( Grocott, MPW; Kumar, SB; Montgomery, HE; Otto, JM; Plumb, JOM; Schmidt, W; Wright, M, 2020)
"Tubulointerstitial fibrosis is a hallmark of chronic progressive kidney disease leading to end-stage renal failure."1.35Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction. ( Choi, ME; He, Y; Kim, SI; Kwak, JH; Lee, JY; Wang, L, 2008)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's8 (38.10)29.6817
2010's6 (28.57)24.3611
2020's6 (28.57)2.80

Authors

AuthorsStudies
Xia, Z1
Zhang, C1
Guo, C1
Song, B1
Hu, W1
Cui, Y1
Xue, Y1
Xia, M1
Xu, D1
Zhang, S1
Fang, J1
Zhang, K1
Zou, X1
Ma, Z1
Liu, X1
Qiu, C1
Xie, L1
Lin, Z1
Li, S1
Wu, Y1
Aoki, Y2
Walker, NM2
Misumi, K2
Mimura, T2
Vittal, R2
McLinden, AP2
Fitzgerald, L2
Combs, MP2
Lyu, D2
Osterholzer, JJ2
Pinsky, DJ2
Lama, VN2
Du, K1
Zhu, Y1
Mao, R1
Qu, Y1
Cui, B1
Ma, Y1
Zhang, X1
Chen, Z1
Nam, JG1
Choi, Y1
Lee, SM1
Yoon, SH1
Goo, JM1
Kim, H1
Plumb, JOM1
Otto, JM1
Kumar, SB1
Wright, M1
Schmidt, W1
Grocott, MPW1
Montgomery, HE1
Laurence, J1
Elhadad, S1
Robison, T1
Terry, H1
Varshney, R1
Woolington, S1
Ghafoory, S1
Choi, ME2
Ahamed, J1
Lin, S1
Juriasingani, S1
Sener, A1
Öztürk, A1
Kayacan, O1
Chen, TL1
Liao, JW1
Chan, WH1
Hsu, CY1
Yang, JD1
Ueng, TH1
Shin, KM1
Lee, KS1
Chung, MP1
Han, J1
Bae, YA1
Kim, TS1
Chung, MJ1
Nakao, A2
Faleo, G1
Nalesnik, MA2
Seda-Neto, J1
Kohmoto, J1
Murase, N2
Wang, G1
Hamid, T1
Keith, RJ1
Zhou, G1
Partridge, CR1
Xiang, X1
Kingery, JR1
Lewis, RK1
Li, Q1
Rokosh, DG1
Ford, R1
Spinale, FG1
Riggs, DW1
Srivastava, S1
Bhatnagar, A1
Bolli, R1
Prabhu, SD1
Schmidt, SL1
Nambiar, AM1
Tayob, N1
Sundaram, B1
Han, MK1
Gross, BH1
Kazerooni, EA1
Chughtai, AR1
Lagstein, A1
Myers, JL1
Murray, S1
Toews, GB1
Martinez, FJ1
Flaherty, KR1
Knaapen, P1
van Dockum, WG1
Bondarenko, O1
Kok, WE1
Götte, MJ1
Boellaard, R1
Beek, AM1
Visser, CA1
van Rossum, AC1
Lammertsma, AA1
Visser, FC1
Neto, JS1
Toyokawa, H1
Romanosky, AJ1
Kimizuka, K1
Kaizu, T1
Hashimoto, N1
Azhipa, O1
Stolz, DB1
Choi, AM1
Tiev, KP1
Cabane, J1
Aubourg, F1
Kettaneh, A1
Ziani, M1
Mouthon, L1
Duong-Quy, S1
Fajac, I1
Guillevin, L1
Dinh-Xuan, AT1
Gautier, M1
Antier, D1
Bonnet, P1
Le Net, JL1
Hanton, G1
Eder, V1
Suliman, HB1
Carraway, MS1
Ali, AS1
Reynolds, CM1
Welty-Wolf, KE1
Piantadosi, CA1
Wang, L1
Lee, JY1
Kwak, JH1
He, Y1
Kim, SI1
Taniguchi, H1
Masuyama, M1
Koyama, H1
Oguro, A1
Takahashi, T1

Reviews

1 review available for carbon monoxide and Fibrosis

ArticleYear
Is hydrogen sulfide a potential novel therapy to prevent renal damage during ureteral obstruction?
    Nitric oxide : biology and chemistry, 2018, 02-28, Volume: 73

    Topics: Animals; Carbon Monoxide; Disease Models, Animal; Fibrosis; Gasotransmitters; Humans; Hydrogen Sulfi

2018

Other Studies

20 other studies available for carbon monoxide and Fibrosis

ArticleYear
Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway.
    Acta biomaterialia, 2022, Volume: 144

    Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Cyclosporine; Fibrosis; Humans; Inflammasomes; M

2022
Risk Factors Associated with Impairment in Pulmonary Diffusing Capacity among Patients with Noncystic Fibrosis Bronchiectasis.
    Canadian respiratory journal, 2022, Volume: 2022

    Topics: Bronchiectasis; Carbon Monoxide; Fibrosis; Humans; Lung Diseases, Interstitial; Pulmonary Diffusing

2022
The mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2023, Volume: 42, Issue:3

    Topics: Allografts; Animals; Bronchiolitis Obliterans; Carbon Monoxide; Collagen; Fibrosis; Graft Rejection;

2023
The mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2023, Volume: 42, Issue:3

    Topics: Allografts; Animals; Bronchiolitis Obliterans; Carbon Monoxide; Collagen; Fibrosis; Graft Rejection;

2023
The mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2023, Volume: 42, Issue:3

    Topics: Allografts; Animals; Bronchiolitis Obliterans; Carbon Monoxide; Collagen; Fibrosis; Graft Rejection;

2023
The mitigating effect of exogenous carbon monoxide on chronic allograft rejection and fibrosis post-lung transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2023, Volume: 42, Issue:3

    Topics: Allografts; Animals; Bronchiolitis Obliterans; Carbon Monoxide; Collagen; Fibrosis; Graft Rejection;

2023
Medium-long term prognosis prediction for idiopathic pulmonary fibrosis patients based on quantitative analysis of fibrotic lung volume.
    Respiratory research, 2022, Dec-22, Volume: 23, Issue:1

    Topics: Carbon Monoxide; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Lung; Prognosis; Retrospective Stu

2022
Prognostic value of deep learning-based fibrosis quantification on chest CT in idiopathic pulmonary fibrosis.
    European radiology, 2023, Volume: 33, Issue:5

    Topics: Aged; Carbon Monoxide; Deep Learning; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; P

2023
Application of the optimized carbon monoxide rebreathing method for the measurement of total haemoglobin mass in chronic liver disease.
    Physiological reports, 2020, Volume: 8, Issue:6

    Topics: Carbon Monoxide; Carboxyhemoglobin; Female; Fibrosis; Hemoglobins; Humans; Liver Diseases; Male; Mid

2020
HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: Animals; Blood Platelets; Carbon Monoxide; Cardiac Output; Echocardiography; Fibrosis; Heart Disease

2017
Rising stars of DPLD survival: FVC and exercise desaturation (a single-center study)
    Turkish journal of medical sciences, 2018, Aug-16, Volume: 48, Issue:4

    Topics: Age Factors; Aged; Blood Pressure; Carbon Monoxide; Connective Tissue Diseases; Exercise; Exercise T

2018
Induction of cardiac fibrosis and transforming growth factor-β1 by motorcycle exhaust in rats.
    Inhalation toxicology, 2013, Volume: 25, Issue:9

    Topics: 7-Alkoxycoumarin O-Dealkylase; Air Pollutants; Animals; Atrial Natriuretic Factor; Carbon Monoxide;

2013
Prognostic determinants among clinical, thin-section CT, and histopathologic findings for fibrotic idiopathic interstitial pneumonias: tertiary hospital study.
    Radiology, 2008, Volume: 249, Issue:1

    Topics: Bronchoalveolar Lavage Fluid; Carbon Monoxide; Female; Fibrosis; Humans; Lung Diseases, Interstitial

2008
Low-dose carbon monoxide inhibits progressive chronic allograft nephropathy and restores renal allograft function.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:1

    Topics: Animals; Atrophy; Carbon Monoxide; Chronic Disease; Disease Models, Animal; Disease Progression; Dos

2009
Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart.
    Circulation, 2010, May-04, Volume: 121, Issue:17

    Topics: Animals; Apoptosis; Carbon Monoxide; Cardiotonic Agents; Chronic Disease; Fibrosis; Gene Expression;

2010
Pulmonary function measures predict mortality differently in IPF versus combined pulmonary fibrosis and emphysema.
    The European respiratory journal, 2011, Volume: 38, Issue:1

    Topics: Aged; Carbon Monoxide; Diffusion; Emphysema; Female; Fibrosis; Forced Expiratory Volume; Humans; Idi

2011
Delayed contrast enhancement and perfusable tissue index in hypertrophic cardiomyopathy: comparison between cardiac MRI and PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:6

    Topics: Adult; Aged; Carbon Monoxide; Cardiomyopathy, Hypertrophic; Case-Control Studies; Chronic Disease; F

2005
Low-dose carbon monoxide inhalation prevents development of chronic allograft nephropathy.
    American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:2

    Topics: Administration, Inhalation; Animals; Carbon Monoxide; Cell Adhesion Molecules; Cytokines; Fibrosis;

2006
Severity of scleroderma lung disease is related to alveolar concentration of nitric oxide.
    The European respiratory journal, 2007, Volume: 30, Issue:1

    Topics: Aged; Carbon Monoxide; Echocardiography; Female; Fibrosis; Humans; Lung Diseases; Lung Diseases, Int

2007
Continuous inhalation of carbon monoxide induces right ventricle ischemia and dysfunction in rats with hypoxic pulmonary hypertension.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2

    Topics: Administration, Inhalation; Animals; Blood Flow Velocity; Blood Pressure; Carbon Monoxide; Carboxyhe

2007
The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:12

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Antibiotics, Antineoplastic; Antimetabolites;

2007
Protective effects of low-dose carbon monoxide against renal fibrosis induced by unilateral ureteral obstruction.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:3

    Topics: Actins; Administration, Inhalation; Animals; Antimetabolites; Carbon Monoxide; Collagen Type I; Epit

2008
Quantitative measurement of human tissue hepatic blood volume by C15O inhalation with positron-emission tomography.
    Liver, 1996, Volume: 16, Issue:4

    Topics: Blood Volume; Carbon Monoxide; Coloring Agents; Female; Fibrosis; Hepatitis; Humans; Indocyanine Gre

1996