carbon monoxide and Complications of Diabetes Mellitus
carbon monoxide has been researched along with Complications of Diabetes Mellitus in 14 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen sulfide (H2S)has emerged as the third gasotransmitter following the nitric oxide and carbon monoxide in the body, and plays an important role in both physiology and pathophysiology." | 6.58 | [Research Advances in Hydrogen Sulfide and Diabetes Mellitus as Well as Diabetic Complications]. ( Gu, Y; Ji, Y; Meng, GL; Xie, LP, 2018) |
| "Diabetic gastroparesis is associated with increased oxidative stress attributable to loss of upregulation of heme oxygenase-1 (HO1), with resultant damage to interstitial cells of Cajal and delayed gastric emptying." | 5.36 | Carbon monoxide reverses diabetic gastroparesis in NOD mice. ( Choi, KM; Dutta, N; Farrugia, G; Gibbons, SJ; Kashyap, PC; Linden, DR; Szurszewski, JH, 2010) |
| "We investigated the pre-clinical utility of carbon monoxide form of PEGylated hemoglobin (PEG-Hb also named SANGUINATE(™)) in myocardial infarction (MI) and in particular the response of diabetic tissues to superimposed ischemia/reperfusion injury." | 3.79 | Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice. ( Abuchowski, A; Ananthakrishnan, R; Li, Q; O'Shea, KM; Quadri, N; Ramasamy, R; Schmidt, AM; Wang, L, 2013) |
| " Cough was the most common adverse event; however, there was no difference in incidence between the AIR insulin (15." | 2.74 | Safety and efficacy of AIR inhaled insulin compared with subcutaneous insulin in patients having diabetes and asthma: A 12-month, randomized, noninferiority trial. ( Ang, E; Berclaz, PY; Ferguson, JA; Heilmann, CR; Lawrence, MK; Tobian, JA; Webb, DM, 2009) |
| "Hydrogen sulfide (H2S)has emerged as the third gasotransmitter following the nitric oxide and carbon monoxide in the body, and plays an important role in both physiology and pathophysiology." | 2.58 | [Research Advances in Hydrogen Sulfide and Diabetes Mellitus as Well as Diabetic Complications]. ( Gu, Y; Ji, Y; Meng, GL; Xie, LP, 2018) |
| "Diabetic gastroparesis is associated with increased oxidative stress attributable to loss of upregulation of heme oxygenase-1 (HO1), with resultant damage to interstitial cells of Cajal and delayed gastric emptying." | 1.36 | Carbon monoxide reverses diabetic gastroparesis in NOD mice. ( Choi, KM; Dutta, N; Farrugia, G; Gibbons, SJ; Kashyap, PC; Linden, DR; Szurszewski, JH, 2010) |
| "However, proteinuria was the only significant independent predictor of DLCO/VA." | 1.30 | Reduction of diffusion capacity for carbon monoxide in diabetic patients. ( Car, N; Drazić, Z; Ljubić, S; Metelko, Z; Roglić, G, 1998) |
Research
Studies (14)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Gu, Y | 1 |
| Xie, LP | 1 |
| Meng, GL | 1 |
| Ji, Y | 1 |
| Paul, S | 1 |
| Andrews, WG | 1 |
| Nasar, A | 1 |
| Port, JL | 1 |
| Lee, PC | 1 |
| Stiles, BM | 1 |
| Altorki, NK | 1 |
| Loboda, A | 1 |
| Jazwa, A | 1 |
| Grochot-Przeczek, A | 1 |
| Rutkowski, AJ | 1 |
| Cisowski, J | 1 |
| Agarwal, A | 1 |
| Jozkowicz, A | 1 |
| Dulak, J | 1 |
| Piepoli, AL | 1 |
| de Salvatore, G | 1 |
| Lemoli, M | 1 |
| de Benedictis, L | 1 |
| Mitolo-Chieppa, D | 1 |
| de Salvia, MA | 1 |
| Ang, E | 1 |
| Lawrence, MK | 1 |
| Heilmann, CR | 1 |
| Ferguson, JA | 1 |
| Tobian, JA | 1 |
| Webb, DM | 1 |
| Berclaz, PY | 1 |
| Kashyap, PC | 1 |
| Choi, KM | 1 |
| Dutta, N | 1 |
| Linden, DR | 1 |
| Szurszewski, JH | 1 |
| Gibbons, SJ | 1 |
| Farrugia, G | 1 |
| Scaramuzza, AE | 1 |
| Morelli, M | 1 |
| Rizzi, M | 1 |
| Borgonovo, S | 1 |
| De Palma, A | 1 |
| Mameli, C | 1 |
| Giani, E | 1 |
| Beretta, S | 1 |
| Zuccotti, GV | 1 |
| Dales, RE | 1 |
| Cakmak, S | 1 |
| Vidal, CB | 1 |
| Rubio, MA | 1 |
| Ananthakrishnan, R | 1 |
| Li, Q | 1 |
| O'Shea, KM | 1 |
| Quadri, N | 1 |
| Wang, L | 1 |
| Abuchowski, A | 1 |
| Schmidt, AM | 1 |
| Ramasamy, R | 1 |
| Peel, JL | 1 |
| Metzger, KB | 1 |
| Klein, M | 1 |
| Flanders, WD | 1 |
| Mulholland, JA | 1 |
| Tolbert, PE | 1 |
| Irvine, C | 1 |
| Wilson, YG | 1 |
| Currie, IC | 1 |
| McGrath, C | 1 |
| Scott, J | 1 |
| Day, A | 1 |
| Stansbie, D | 1 |
| Baird, RN | 1 |
| Lamont, PM | 1 |
| Ljubić, S | 1 |
| Metelko, Z | 1 |
| Car, N | 1 |
| Roglić, G | 1 |
| Drazić, Z | 1 |
| Marshall, M | 1 |
| Clarkson, TB | 1 |
| Lehner, ND | 1 |
| Bullock, BC | 1 |
| Lofland, HB | 1 |
| Wagner, WD | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pivotal, Open-Label, Parallel Study to Evaluate the Safety and Efficacy of Human Insulin Inhalation Powder (HIIP) Compared to Injectable Insulin in Patients With Diabetes and COPD or Asthma[NCT00157339] | Phase 3 | 299 participants (Actual) | Interventional | 2005-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
3 reviews available for carbon monoxide and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
[Research Advances in Hydrogen Sulfide and Diabetes Mellitus as Well as Diabetic Complications].
Topics: Carbon Monoxide; Diabetes Complications; Diabetes Mellitus; Humans; Hydrogen Sulfide; Nitric Oxide | 2018 |
Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities.
Topics: Animals; Apoptosis; Biliverdine; Carbon Monoxide; Cardiovascular Agents; Cardiovascular Diseases; Ch | 2008 |
Atherosclerosis in new world monkeys.
Topics: Age Factors; Alouatta; Animals; Aorta; Arteriosclerosis; Callitrichinae; Carbon Monoxide; Cholelithi | 1976 |
Trials
1 trial available for carbon monoxide and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Safety and efficacy of AIR inhaled insulin compared with subcutaneous insulin in patients having diabetes and asthma: A 12-month, randomized, noninferiority trial.
Topics: Administration, Inhalation; Adult; Age of Onset; Aged; Asthma; Body Mass Index; Carbon Monoxide; Dia | 2009 |
Other Studies
10 other studies available for carbon monoxide and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Outcomes of lobectomy in patients with severely compromised lung function (predicted postoperative diffusing capacity of the lung for carbon monoxide % ≤ 40%).
Topics: Aged; Aged, 80 and over; Antimetabolites; Carbon Monoxide; Cohort Studies; Diabetes Complications; F | 2013 |
Modulation of heme oxygenase/carbon monoxide system affects the inhibitory neurotransmission involved in gastrointestinal motility of streptozotocin-treated diabetic rats.
Topics: Animals; Blotting, Western; Carbon Monoxide; Diabetes Complications; Diabetes Mellitus, Experimental | 2008 |
Carbon monoxide reverses diabetic gastroparesis in NOD mice.
Topics: Animals; Carbon Monoxide; Diabetes Complications; Female; Gastric Emptying; Gastroparesis; Mice; Mic | 2010 |
Impaired diffusing capacity for carbon monoxide in children with type 1 diabetes: is this the first sign of long-term complications?
Topics: Adolescent; Carbon Monoxide; Case-Control Studies; Child; Cohort Studies; Diabetes Complications; Di | 2012 |
Air pollution and hospitalization for acute complications of diabetes in Chile.
Topics: Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Carbon Monoxide; Chile; Coma; Diabetes Compl | 2012 |
Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice.
Topics: Animals; Biomarkers; Blood Substitutes; Carbon Monoxide; Diabetes Complications; Energy Metabolism; | 2013 |
Ambient air pollution and cardiovascular emergency department visits in potentially sensitive groups.
Topics: Air Pollution; Carbon Monoxide; Cardiovascular Diseases; Comorbidity; Cross-Over Studies; Diabetes C | 2007 |
Hyperhomocysteinaemia is a risk factor for vein graft stenosis.
Topics: Adult; Aged; Arterial Occlusive Diseases; Carbon Monoxide; Case-Control Studies; Constriction, Patho | 1996 |
Reduction of diffusion capacity for carbon monoxide in diabetic patients.
Topics: Adult; Carbon Monoxide; Chromatography, Ion Exchange; Chronic Disease; Diabetes Complications; Diabe | 1998 |
[Clinical consequences of the "thrombocytogenic" theory of atherogenesis].
Topics: Animals; Arterial Occlusive Diseases; Carbon Monoxide; Cholesterol, Dietary; Diabetes Complications; | 1979 |