Page last updated: 2024-10-16

carbon monoxide and Chronic Lung Injury

carbon monoxide has been researched along with Chronic Lung Injury in 15 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Research Excerpts

ExcerptRelevanceReference
"Lung ischemia-reperfusion injury (IRI) may be attenuated through carbon monoxide (CO)'s anti-inflammatory effect or hydrogen (H2)'s anti-oxidant effect."7.83Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats. ( Cui, X; Jiang, C; Kang, J; Liu, J; Liu, R; Ma, L; Meng, C; Niu, L; Xing, J; Zhou, H, 2016)
"Lung ischemia-reperfusion injury (IRI) may be attenuated through carbon monoxide (CO)'s anti-inflammatory effect or hydrogen (H2)'s anti-oxidant effect."3.83Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats. ( Cui, X; Jiang, C; Kang, J; Liu, J; Liu, R; Ma, L; Meng, C; Niu, L; Xing, J; Zhou, H, 2016)
"We sought to determine whether ventilation of lungs after death in non-heart-beating donors with carbon monoxide during warm ischemia and ex vivo lung perfusion and after transplant would reduce ischemia-reperfusion injury and improve lung function."3.79Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors. ( Dong, B; Egan, TM; Stewart, PW, 2013)
" Although the effectiveness of HbVs, including their physicochemical characteristics and pharmacological effects, has been reported, data on the pharmacokinetic properties of HbVs are limited."2.58[Safety Evaluation of Cellular-type Artificial Blood Based on Pharmacokinetic Analysis and Its Use in Medical Gas Delivery]. ( Taguchi, K, 2018)
"Chronic obstructive pulmonary disease (COPD) is a disease involving airways restriction, alveolar destruction, and loss of lung function, primarily due to cigarette smoke (CS) exposure."2.48Heme Oxygenase-1/CO as protective mediators in cigarette smoke- induced lung cell injury and chronic obstructive pulmonary disease. ( Choi, AM; Dolinay, T; Ryter, SW, 2012)
"Although many diseases, including cancer, hematological diseases, hypertension, heart failure, inflammation, sepsis, neurodegeneration, and sleep disorders, have been linked to abnormal endogenous CO metabolism and functions, CO administration has therapeutic potential in inflammation, sepsis, lung injury, cardiovascular diseases, transplantation, and cancer."2.48Carbon monoxide: an unusual drug. ( Ascenzi, P; di Masi, A; Gullotta, F, 2012)
"Carbon monoxide (250 ppm) was given for 1 hour after termination of CPB."1.37Postconditioning of the lungs with inhaled carbon monoxide after cardiopulmonary bypass in pigs. ( Brehm, K; Goebel, U; Loop, T; Priebe, HJ; Schibilsky, D; Schlensak, C; Schwer, CI; Siepe, M, 2011)
"In a model of acute lung injury in mice, CO blocked expression of Egr-1, a central mediator of inflammation, and decreased tissue damage; inhibition of PPARgamma abrogated both effects."1.33Carbon monoxide orchestrates a protective response through PPARgamma. ( Bach, FH; Bilban, M; Chin, BY; d'Avila, JC; Esterbauer, H; Ifedigbo, E; Otterbein, LE; Otterbein, SL; Robson, SC; Usheva, A; Wagner, O, 2006)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (40.00)29.6817
2010's9 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cho, HJ1
Lee, SY2
Park, D1
Ryu, SH1
Yoon, J1
Jung, S1
Lee, E1
Yang, SI1
Hong, SJ1
Taguchi, K1
Maignan, M1
Briot, R1
Romanini, D1
Gennai, S1
Hazane-Puch, F1
Brouta, A1
Debaty, G1
Ventrillard, I1
Meng, C1
Ma, L1
Niu, L1
Cui, X1
Liu, J1
Kang, J1
Liu, R1
Xing, J1
Jiang, C1
Zhou, H1
Smith-Sivertsen, T1
Díaz, E1
Pope, D1
Lie, RT1
Díaz, A1
McCracken, J1
Bakke, P1
Arana, B1
Smith, KR1
Bruce, N1
Goebel, U1
Siepe, M1
Schwer, CI1
Schibilsky, D1
Brehm, K1
Priebe, HJ1
Schlensak, C1
Loop, T1
Dolinay, T1
Choi, AM1
Ryter, SW1
Gullotta, F1
di Masi, A1
Ascenzi, P1
Dong, B1
Stewart, PW1
Egan, TM1
Zolak, JS1
Jagirdar, R1
Surolia, R1
Karki, S1
Oliva, O1
Hock, T1
Guroji, P1
Ding, Q1
Liu, RM1
Bolisetty, S1
Agarwal, A1
Thannickal, VJ1
Antony, VB1
Zhang, X1
Shan, P1
Alam, J1
Davis, RJ1
Flavell, RA1
Lee, PJ1
Kim, YJ2
Bilban, M1
Bach, FH1
Otterbein, SL1
Ifedigbo, E1
d'Avila, JC1
Esterbauer, H1
Chin, BY1
Usheva, A1
Robson, SC1
Wagner, O1
Otterbein, LE2
Sun, BW1
Chen, X1
Chen, ZY1
Katada, K1
Cepinskas, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Particulate Air Pollution Exposure and Childhood Acute Respiratory Infections in Guatemala: A Randomized Intervention[NCT01047696]537 participants (Actual)Interventional2002-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for carbon monoxide and Chronic Lung Injury

ArticleYear
[Safety Evaluation of Cellular-type Artificial Blood Based on Pharmacokinetic Analysis and Its Use in Medical Gas Delivery].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:11

    Topics: Acute Disease; Animals; Blood Substitutes; Carbon Monoxide; Disease Models, Animal; Drug Carriers; D

2018
Heme Oxygenase-1/CO as protective mediators in cigarette smoke- induced lung cell injury and chronic obstructive pulmonary disease.
    Current pharmaceutical biotechnology, 2012, Volume: 13, Issue:6

    Topics: Animals; Carbon Monoxide; Heme Oxygenase-1; Humans; Lung Injury; Pulmonary Disease, Chronic Obstruct

2012
Carbon monoxide: an unusual drug.
    IUBMB life, 2012, Volume: 64, Issue:5

    Topics: Animals; Carbon Monoxide; Cardiovascular Diseases; Enzyme Induction; Heme Oxygenase-1; Humans; Infla

2012
Carbon monoxide: innovative anti-inflammatory properties of an age-old gas molecule.
    Antioxidants & redox signaling, 2002, Volume: 4, Issue:2

    Topics: Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cell Hypoxia; Disease

2002

Trials

1 trial available for carbon monoxide and Chronic Lung Injury

ArticleYear
Effect of reducing indoor air pollution on women's respiratory symptoms and lung function: the RESPIRE Randomized Trial, Guatemala.
    American journal of epidemiology, 2009, Jul-15, Volume: 170, Issue:2

    Topics: Adolescent; Adult; Air Pollution, Indoor; Carbon Monoxide; Confidence Intervals; Cooking; Cooking an

2009

Other Studies

10 other studies available for carbon monoxide and Chronic Lung Injury

ArticleYear
Early-life exposure to humidifier disinfectant determines the prognosis of lung function in children.
    BMC pulmonary medicine, 2019, Dec-23, Volume: 19, Issue:1

    Topics: Carbon Monoxide; Case-Control Studies; Child; Disinfectants; Female; Follow-Up Studies; Forced Expir

2019
Real-time measurements of endogenous carbon monoxide production in isolated pig lungs.
    Journal of biomedical optics, 2014, Volume: 19, Issue:4

    Topics: Animals; Carbon Monoxide; Heme Oxygenase-1; Lasers; Lung; Lung Injury; Monitoring, Physiologic; Repe

2014
Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats.
    Life sciences, 2016, Apr-15, Volume: 151

    Topics: Animals; Apoptosis; Blood Gas Analysis; Carbon Monoxide; Cold Ischemia; Drug Synergism; Hydrogen; In

2016
Postconditioning of the lungs with inhaled carbon monoxide after cardiopulmonary bypass in pigs.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:2

    Topics: Administration, Inhalation; Animals; Apoptosis; Biopsy; Carbon Monoxide; Cardiopulmonary Bypass; Cas

2011
Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors.
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 146, Issue:2

    Topics: Animals; Blotting, Western; Carbon Monoxide; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Extracel

2013
Pleural mesothelial cell differentiation and invasion in fibrogenic lung injury.
    The American journal of pathology, 2013, Volume: 182, Issue:4

    Topics: Administration, Inhalation; Animals; Biomarkers; Carbon Monoxide; Cell Differentiation; Cell Movemen

2013
Carbon monoxide modulates Fas/Fas ligand, caspases, and Bcl-2 family proteins via the p38alpha mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury.
    The Journal of biological chemistry, 2003, Jun-13, Volume: 278, Issue:24

    Topics: Animals; Apoptosis; Carbon Monoxide; Caspase 3; Caspase 8; Caspase 9; Caspases; Cytochrome c Group;

2003
Role of crosslinked protein in lung injury following total body irradiation and bone marrow transplantation.
    Experimental & molecular medicine, 2003, Dec-31, Volume: 35, Issue:6

    Topics: Animals; Bone Marrow Transplantation; Carbon Monoxide; Factor XIII; Female; Lung; Lung Injury; Mice;

2003
Carbon monoxide orchestrates a protective response through PPARgamma.
    Immunity, 2006, Volume: 24, Issue:5

    Topics: Animals; Blotting, Western; Carbon Monoxide; Disease Models, Animal; Early Growth Response Protein 1

2006
[Molecular mechanism of inhibition of early pulmonary injury and inflammatory response by exogenous carbon monoxide: experiment with mice].
    Zhonghua yi xue za zhi, 2007, Nov-27, Volume: 87, Issue:44

    Topics: Animals; Blotting, Western; Burns; Carbon Monoxide; Cell Adhesion; Disease Models, Animal; Electroph

2007