Page last updated: 2024-10-16

carbon monoxide and Chronic Illness

carbon monoxide has been researched along with Chronic Illness in 114 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Research Excerpts

ExcerptRelevanceReference
"To examine the pattern of immunoglobulins and cellular constituents in bronchoalveolar lavage fluid obtained from patients with sulfur mustard gas-induced asthma or chronic bronchitis as compared with healthy control subjects."7.70Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis. ( Emad, A; Rezaian, GR, 1999)
"The effects of carbon monoxide on exercise tolerance as assessed by the distance walked in 12 minutes were studied in 15 patients with severe chronic bronchitis and emphysema (mean forced expiratory volume in one second 0."7.66Carbon monoxide and exercise tolerance in chronic bronchitis and emphysema. ( Calverley, PM; Flenley, DC; Leggett, RJ, 1981)
"Clinical and physiologic data on chronic carbon monoxide poisoning are reviewed and the results of an investigation involving 7 garages in the Lausanne (Switzerland) area are reported."7.65[Risk of chronic carbon monoxide poisoning in automobile garages. Results of a study in the Lausanne region]. ( Köhl, U; Lob, M, 1975)
"Smokers with chronic obstructive pulmonary disease (COPD) have particular difficulty quitting."6.87Effect of Long-term Nicotine Replacement Therapy vs Standard Smoking Cessation for Smokers With Chronic Lung Disease: A Randomized Clinical Trial. ( Ellerbeck, EF; Fitzgerald, SA; Hutcheson, TD; Nollen, N; Phadnis, M; Richter, KP; Salzman, GA; Sharpe, MR; Vacek, J, 2018)
"There was increased mortality in interstitial lung disease‒PH as compared with chronic obstructive pulmonary disease‒PH, but PH severity based on the WHO classification did not alter survival."5.51Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide. ( Archer, SL; Misialek, JR; Prins, KW; Pritzker, M; Rose, L; Thenappan, T; Weir, EK, 2019)
"Fourteen patients with ischemic left ventricular dysfunction were studied with positron emission tomography, using oxygen-15-labeled water and carbon monoxide as tracers, and with contrast-enhanced MRI."5.15Prediction of functional recovery after revascularization in patients with chronic ischemic myocardial dysfunction: perfusable tissue index by positron emission tomography and contrast-enhanced MRI comparison study. ( Beek, AM; Boellaard, R; Bondarenko, O; Knaapen, P; Lammertsma, AA; van Rossum, AC, 2011)
"Chimonin can reduce pulmonary hypertension and pulmonary vessel remodeling induced by hypoxic hypercapnia through inhibiting proliferation of collagen I, the mechanism maybe is up regulating endogenous carbon monoxide system."3.76[The effect of chimonin on collagen metabolism of pulmonary arterioles in chronic hypoxic rats]. ( Huang, XY; Qian, GQ; Wang, LX; Xu, XM, 2010)
"We investigated the association between chronic carbon monoxide (CO) exposure and electrocardiographic maximum/minimum P-wave duration (Pmax/Pmin), P-wave dispersion (Pd), maximum/minimum QT interval (QTmax/QTmin), and QT and corrected QT dispersion (QTd/cQTd), which are known as predictors of atrial fibrillation, ventricular arrhythmias, and sudden death."3.74Chronic carbon monoxide exposure increases electrocardiographic P-wave and QT dispersion. ( Aksoy, M; Davutoglu, V; Ozer, O; Sari, I; Yildirim, C; Zengin, S, 2008)
" In multivariate analysis, chronic graft-versus-host disease (relative risk, 16) and pretransplantation diffusion capacity for carbon monoxide or forced expiratory volume in the first second <80% predicted were independently associated with a late decrease in PF from baseline (relative risk, 7)."3.73Chronic GVHD and pretransplantation abnormalities in pulmonary function are the main determinants predicting worsening pulmonary function in long-term survivors after stem cell transplantation. ( Barrett, AJ; Childs, R; Karimpour, S; Mielke, S; Montero, A; Rezvani, K; Savani, BN; Shenoy, A; Singh, A; Srinivasan, R, 2006)
" This study was designed to evaluate the effect of body position on diffusing capacity for carbon monoxide (DLco), Dm and Vc in male patients with chronic bronchitis and pulmonary emphysema."3.70Body position, membrane diffusing capacity and pulmonary capillary blood volume in chronic bronchitis and pulmonary emphysema. ( Chang, HI; Chang, SC; Chou, KC; Shiao, GM, 1999)
"To examine the pattern of immunoglobulins and cellular constituents in bronchoalveolar lavage fluid obtained from patients with sulfur mustard gas-induced asthma or chronic bronchitis as compared with healthy control subjects."3.70Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis. ( Emad, A; Rezaian, GR, 1999)
"The effects of carbon monoxide on exercise tolerance as assessed by the distance walked in 12 minutes were studied in 15 patients with severe chronic bronchitis and emphysema (mean forced expiratory volume in one second 0."3.66Carbon monoxide and exercise tolerance in chronic bronchitis and emphysema. ( Calverley, PM; Flenley, DC; Leggett, RJ, 1981)
"Clinical and physiologic data on chronic carbon monoxide poisoning are reviewed and the results of an investigation involving 7 garages in the Lausanne (Switzerland) area are reported."3.65[Risk of chronic carbon monoxide poisoning in automobile garages. Results of a study in the Lausanne region]. ( Köhl, U; Lob, M, 1975)
"Smokers with chronic obstructive pulmonary disease (COPD) have particular difficulty quitting."2.87Effect of Long-term Nicotine Replacement Therapy vs Standard Smoking Cessation for Smokers With Chronic Lung Disease: A Randomized Clinical Trial. ( Ellerbeck, EF; Fitzgerald, SA; Hutcheson, TD; Nollen, N; Phadnis, M; Richter, KP; Salzman, GA; Sharpe, MR; Vacek, J, 2018)
"A double-blind, Latin-square, placebo-controlled, dose-response study was conducted in an inpatient general clinical research center and clinical pharmacology unit of a university teaching hospital."2.68Cocaine effects on digital blood flow and diffusing capacity for carbon monoxide among chronic cocaine users. ( Becker, PM; Jasinski, DR; Preston, KL; Sullivan, JT; Testa, MP; Wigely, FM; Wise, RA, 1997)
"Current invasive measures of pulmonary inflammation include markers in blood and airway effluent, with the cellular composition of tracheal fluid being the "gold standard"."2.43Exhaled breath measures of inflammation: are they useful in neonatal chronic lung disease? ( Andersen, CC; Harrison, CM, 2005)
"Leflunomide treatment was associated with significant gastrointestinal and other adverse effects leading 40% of patients to discontinue therapy."1.56Use of leflunomide in patients with chronic hypersensitivity pneumonitis. ( Culver, DA; Li, M; Noh, S; Pande, A; Sahoo, D; Wang, X; Yadav, R, 2020)
"Higher MELD-Na score, hepatic encephalopathy, impaired DLCO, clubbing, and spider naevi were independently associated with HPS."1.56Prevalence and determinants of hepatopulmonary syndrome in decompensated chronic liver disease. ( Joshi, S; Kanala, JR; Kareem, H; Khiangte, B; Kothakota, SR; Kumar C, P; Kumar, VV; Nair, AK; Sasidharan, M, 2020)
"There was increased mortality in interstitial lung disease‒PH as compared with chronic obstructive pulmonary disease‒PH, but PH severity based on the WHO classification did not alter survival."1.51Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide. ( Archer, SL; Misialek, JR; Prins, KW; Pritzker, M; Rose, L; Thenappan, T; Weir, EK, 2019)
"The treatment of chronic hypersensitivity pneumonitis (cHP) often includes systemic oral corticosteroids, but the optimal pharmacologic management remains unclear."1.46Use of Mycophenolate Mofetil or Azathioprine for the Management of Chronic Hypersensitivity Pneumonitis. ( Aravena, C; Collard, HR; Dubé, BP; Elicker, BM; Fell, CD; Johannson, KA; Jones, KD; Ley, B; Manganas, H; Morisset, J; Ryerson, CJ; Vittinghoff, E; Wolters, PJ, 2017)
"Idiopathic chronic eosinophilic pneumonia was confirmed after exclusion of other causes of eosinophilic pneumonia and systemic disease."1.39Chronic eosinophilic pneumonia with persistent decreased diffusing capacity for carbon monoxide. ( Albertini, M; Blanc, S; Giovannini-Chami, L; Leroy, S, 2013)
"All subjects received periodontal treatment and smoking cessation advice as part of an individual, patient-based programme provided by dental hygienists trained in smoking cessation counselling."1.33Smoking cessation advice for patients with chronic periodontitis. ( Heasman, L; Heasman, PA; Nasry, HA; Preshaw, PM; Stacey, F; Swan, M, 2006)
"Carbon monoxide treatment was achieved by a new pharmacological approach in transplantation using methylene chloride (MC), which releases CO after degradation."1.31Gene transfer of heme oxygenase-1 and carbon monoxide delivery inhibit chronic rejection. ( Anegon, I; Bouchet, D; Braudeau, C; Buelow, R; Chauveau, C; Iyer, S; Mathieu, P; Renaudin, K; Roussel, JC; Soulillou, JP; Tesson, L, 2002)
"To define the relationship between hypoxemia and VCO/VCO2 deficit."1.31[Pulmonary circulatory amputation in chronic respiratory insufficiency. Simple, anodyne, and fast evaluation]. ( Bréant, J; Fleury, MF, 2001)
"However, proteinuria was the only significant independent predictor of DLCO/VA."1.30Reduction of diffusion capacity for carbon monoxide in diabetic patients. ( Car, N; Drazić, Z; Ljubić, S; Metelko, Z; Roglić, G, 1998)

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-199055 (48.25)18.7374
1990's15 (13.16)18.2507
2000's27 (23.68)29.6817
2010's12 (10.53)24.3611
2020's5 (4.39)2.80

Authors

AuthorsStudies
Ahlgrim, C2
Birkner, P2
Seiler, F2
Grundmann, S2
Bode, C2
Pottgiesser, T2
Schoechlin, S1
Fiddler, CA1
Simler, N1
Thillai, M1
Parfrey, H1
Rylance, S1
Nightingale, R1
Naunje, A1
Mbalume, F1
Jewell, C1
Balmes, JR1
Grigg, J1
Mortimer, K1
Wachsmuth, N1
Soria, R1
Jimenez, J1
Schmidt, W1
Terras Alexandre, A1
Martins, N1
Raimundo, S1
Melo, N1
Catetano Mota, P1
Novais E Bastos, H1
Pereira, JM1
Cunha, R1
Guimarães, S1
Souto Moura, C1
Morais, A1
Noh, S1
Yadav, R1
Li, M1
Wang, X1
Sahoo, D1
Culver, DA1
Pande, A1
Khiangte, B1
Kothakota, SR1
Sasidharan, M1
Kareem, H1
Joshi, S1
Kumar, VV1
Kanala, JR1
Kumar C, P1
Nair, AK1
Rose, L1
Prins, KW1
Archer, SL1
Pritzker, M1
Weir, EK1
Misialek, JR1
Thenappan, T1
Ellerbeck, EF1
Nollen, N1
Hutcheson, TD1
Phadnis, M1
Fitzgerald, SA1
Vacek, J1
Sharpe, MR1
Salzman, GA1
Richter, KP1
Blanc, S1
Albertini, M1
Leroy, S1
Giovannini-Chami, L1
Nielsen, VG1
Kulin, W1
LaWall, JS1
MacFarland, FN1
Chen, A1
Hadley, HA1
DaDeppo, AJ1
Steinbrenner, EB1
Matika, RW1
Morisset, J1
Johannson, KA1
Vittinghoff, E1
Aravena, C1
Elicker, BM1
Jones, KD1
Fell, CD1
Manganas, H1
Dubé, BP1
Wolters, PJ1
Collard, HR1
Ryerson, CJ1
Ley, B1
Sari, I1
Zengin, S1
Ozer, O1
Davutoglu, V1
Yildirim, C1
Aksoy, M1
Roulaud, M1
Donal, E1
Raud-Raynier, P1
Denjean, A1
de Bisschop, C1
Nakao, A1
Faleo, G1
Nalesnik, MA1
Seda-Neto, J1
Kohmoto, J1
Murase, N1
Funauchi, M1
Kishimoto, K1
Kinoshita, K1
Wang, G1
Hamid, T1
Keith, RJ1
Zhou, G1
Partridge, CR1
Xiang, X1
Kingery, JR1
Lewis, RK1
Li, Q1
Rokosh, DG1
Ford, R1
Spinale, FG1
Riggs, DW1
Srivastava, S1
Bhatnagar, A1
Bolli, R1
Prabhu, SD1
Huang, XY1
Xu, XM1
Qian, GQ1
Wang, LX1
Bondarenko, O2
Knaapen, P2
Beek, AM2
Boellaard, R2
Lammertsma, AA2
van Rossum, AC2
Kar-Purkayastha, I1
Finlay, S1
Murray, V1
Mohamed, R1
Freeman, JW1
Guest, PJ1
Davies, MK1
Neuberger, JM1
Chauveau, C1
Bouchet, D1
Roussel, JC1
Mathieu, P1
Braudeau, C1
Renaudin, K1
Tesson, L1
Soulillou, JP1
Iyer, S1
Buelow, R1
Anegon, I1
Christensen, CC1
Ryg, MS1
Refvem, OK1
Skjønsberg, OH1
Mathieu-Nolf, M1
Agostoni, PG1
Bussotti, M1
Palermo, P1
Guazzi, M1
BOURGUIGNON, G1
TRUHAUT, R1
DAKAK, M1
LOB, M2
MULLER, A1
SAPIN-JALOUSTRE, H1
GARBAGNI, R1
CARELLI, E1
RANDOWA, D1
SIERAWSKI, S1
Lassinger, BK1
Kwak, C1
Walford, RL1
Jankovic, J1
Rutherford, RM1
Brutsche, MH1
Kearns, M1
Bourke, M1
Stevens, F1
Gilmartin, JJ1
Harrison, CM1
Andersen, CC1
Dubuis, E1
Potier, M1
Wang, R1
Vandier, C1
van Dockum, WG1
Kok, WE1
Götte, MJ1
Visser, CA1
Visser, FC1
Vitali, SH1
Mitsialis, SA1
Christou, H1
Fernandez-Gonzalez, A1
Liu, X1
Kourembanas, S1
Iwakiri, Y1
Groszmann, RJ1
Nasry, HA1
Preshaw, PM1
Stacey, F1
Heasman, L1
Swan, M1
Heasman, PA1
Mitlyng, BL1
Singh, JA1
Furne, JK1
Ruddy, J1
Levitt, MD1
Forastiere, F1
Stafoggia, M1
Tasco, C1
Picciotto, S1
Agabiti, N1
Cesaroni, G1
Perucci, CA1
Krediet, TG1
Cirkel, GA1
Vreman, HJ2
Wong, RJ1
Stevenson, DK2
Groenendaal, F1
Egberts, J1
Van Bel, F1
Savani, BN1
Montero, A1
Srinivasan, R1
Singh, A1
Shenoy, A1
Mielke, S1
Rezvani, K1
Karimpour, S1
Childs, R1
Barrett, AJ1
Cançado, JE1
Braga, A1
Pereira, LA1
Arbex, MA1
Saldiva, PH1
Santos, Ude P1
Gullu, H1
Caliskan, M1
Ciftci, O1
Erdogan, D1
Topcu, S1
Yildirim, E1
Yildirir, A1
Muderrisoglu, H1
Kim, TS1
Kim, DJ1
Lee, H1
Kim, YK1
James, F1
Rumble, L1
Pappenheimer, JR1
Calverley, PM1
Leggett, RJ1
Flenley, DC1
Dhindsa, DS1
Ochsner, AJ1
Borst, JR1
Claude, JR1
Efthymiou, ML1
Thunedborg, P1
Nielsen, AL1
Brinkenfeldt, H1
Brahm, J1
Jensen, HA1
Bréant, J2
Fleury, MF2
Goudin, J1
Bance, N1
Thorpe, M1
Mahoney, JJ1
Sullivan, JT1
Becker, PM1
Preston, KL1
Wise, RA1
Wigely, FM1
Testa, MP1
Jasinski, DR1
Emad, A2
Rezaian, GR2
Yamauchi, H1
Fukuyama, H1
Nagahama, Y1
Katsumi, Y1
Okazawa, H1
Long, W1
Tate, RB1
Neuman, M1
Manfreda, J1
Becker, AB1
Anthonisen, NR1
Ljubić, S1
Metelko, Z1
Car, N1
Roglić, G1
Drazić, Z1
Chou, KC1
Chang, SC1
Chang, HI1
Shiao, GM1
Woehlck, HJ1
Connolly, LA1
Cinquegrani, MP1
Dunning, MB1
Hoffmann, RG1
Di Giulio, C1
Grilli, A1
Ciocca, I1
Macrì, MA1
Daniele, F1
Sabatino, G1
Cacchio, M1
De Lutiis, MA1
Da Porto, R1
Di Natale, F1
Felaco, M1
O'Donaughy, TL1
Walker, BR1
Köhl, U1
Patsch, J2
McConn, R1
Ribon, A1
Perera, S1
Gavencak, J1
Magnussen, H1
Holle, JP1
Hartmann, V1
Schoenen, JD1
Hebbel, RP1
Eaton, JW1
Modler, S1
Jacob, HS1
Sassa, S1
Kappas, A1
Bernstein, SE1
Alvares, AP1
Cordasco, EM1
VanOrdstrand, HS1
Vanuxem, D1
Guillot, C1
Fornaris, E1
Weiller, PJ1
Grimaud, C1
Newth, CJ1
Cotton, DJ1
Nadel, JA1
Zorn, H2
Benatar, SR1
Clark, TJ1
Cochrane, GM1
Dueva, LA1
Tolmachev, DA1
Volkova, AP1
Mitacek, EJ1
Brunnemann, KD1
Polednak, AP1
Hoffmann, D1
Suttajit, M1
Moinard, J1
Guenard, H1
Pham, QT3
Mur, JM1
Teculescu, D1
Chau, N1
Gabiano, M1
Gaertner, M1
Henquel, JC1
Sirota, AD1
Curran, JP1
Habif, V1
Anderhub, HP1
Hofer, P1
Scherrer, M1
Franks, H1
Uffholtz, H1
Schrijen, F1
Boushy, SF1
Lüderitz, P1
Burrows, B1
Weiss, EB1
Desforges, JF1
Reinert, M1
Trendelenburg, F1
Schmidt, F1
Lopez-Majano, V1
Dutton, RE1
Banner, AS1
Uzawa, T1
Osada, H1
Isoyama, Y1
Nonaka, T1
Tajima, G1
Myre, M1
Martin, J1
Knelson, J1
Graimprey, J1
Jain, BP1
Pande, JN1
Guleria, JS1
Muldoon, BC1
Turner-Warwick, M1
Cabal, C1
Kanagami, H1
Nagashima, T1
Saito, T1
Lacoste, J1
Regan, GM1
Tagg, B1
Walford, J1
Thomson, ML1
Saidel, GM1
Militano, TC1
Chester, EH1
Vandenbergh, E1
Billiet, L1
Van de Woestijne, KP1
Gyselen, A1
Gabriel, S1
Palmer, KN1
Diament, ML1
Kreukniet, J1
Bilchik, RC1
Muller-Bergh, HA1
Freshman, ME1
Mitchell, MM1
Renzetti, AD1
Goldsmith, JR1
Ciuhandu, G1
Rusu, V1
Diaconovici, M1
Kiss, L1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Smoking Cessation Versus Long-term Nicotine Replacement Among High-risk Smokers[NCT02148445]Phase 3398 participants (Actual)Interventional2014-05-31Completed
Comparison of the Concentration of Estrogen and Testosterone Ratio in Male Patients With Cirrhosis and Hypotension Compared to Male Cirrhosis Patients Without Hypotension[NCT05051293]0 participants (Actual)Observational2021-08-22Withdrawn (stopped due to Study will be changed from prospective to retrospective)
Phase II Trial of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for Treatment of Bronchiolitis Obliterans Syndrome[NCT01287078]Phase 225 participants (Actual)Interventional2011-01-29Completed
The Effectiveness of Rhinopharyngeal Retrograde Clearance on the Upper Airways Symptomatology and Function in Adults[NCT01976039]24 participants (Actual)Interventional2012-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Respiratory Function

Change in respiratory function, as measured by spirometry (FEV1), at 12 months post-randomization. (NCT02148445)
Timeframe: Month 12

Intervention% of predicted (Mean)
Standard Smoking Cessation55.4
Extended Nicotine Replacement Therapy56.8

Smoking Abstinence (Point Prevalent)

7-day point prevalent abstinence at 12 months, confirmed by exhaled CO <=10 (NCT02148445)
Timeframe: Month 12

InterventionParticipants (Count of Participants)
Standard Smoking Cessation23
Extended Nicotine Replacement Therapy24

Sustained Abstinence

"6 month sustained abstinence as measured by self-report at 6 and 12 months and confirmed by CO at 6 and 12 months. Participants who were confirmed as non-smokers by carbon monoxide (CO) at both Month 6 and Month 12 were considered to have 6-month sustained abstinence." (NCT02148445)
Timeframe: Month 6 through Month 12

InterventionParticipants (Count of Participants)
Standard Smoking Cessation15
Extended Nicotine Replacement Therapy12

7-day Abstinence

"Self-reported and biochemically verified 7-day abstinence. Participants were asked at Month 3, Month 6, and Month 12, Have you smoked any cigarettes or little cigars, even a puff, in the past 7 days? They also completed an exhaled carbon monoxide lab test at Month 3, 6 and 12. Biochemical verification= exhaled CO <=10 ppm. Month 12 biochemically verified abstinence is the primary outcome, and is not reported in this table." (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
InterventionParticipants (Count of Participants)
Month 3, self-reportMonth 3, biochemically verifiedMonth 6, self-reportMonth 6, biochemically verifiedMonth 12, self-report
Extended Nicotine Replacement Therapy1614201928
Standard Smoking Cessation2725282525

Average Cigarettes Per Day

"Average number of cigarettes per day over one year. Participants were asked at Month 3, Month 6, and Month 12 During the past 7 days, on those days that you smoked, what was the average number of cigarettes or little cigars smoked per day?" (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventioncigarettes per day (Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy10.59.18.1
Standard Smoking Cessation7.98.18.5

Average Cigarettes Per Day (Continued Smokers Only)

"Average number of cigarettes per day over one year, among continued smokers. All participants were asked During the past 7 days, on those days that you smoked, what was the average number of cigarettes smoked per day? at Month 3, Month 6, and Month 12. This analysis looks at the number of cigarettes per day among participants who were still smoking." (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventioncigarettes per day (Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy11.49.99.3
Standard Smoking Cessation8.79.19.7

Carbon Monoxide Exposure

Carbon monoxide (CO) exposure over 12 months. At Month 3, Month 6, and Month 12, participants completed an expired carbon monoxide laboratory test, which measured CO in parts per million. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventionparts per million (ppm) (Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy17.415.413.8
Standard Smoking Cessation15.014.615.5

Carbon Monoxide Exposure (Continued Smokers Only)

Carbon monoxide (CO) exposure over 12 months. At Month 3, Month 6, and Month 12, participants completed an expired carbon monoxide laboratory test, which measured CO in parts per million. This analysis looks at CO among those continuing to smoke. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventionparts per million (ppm) (Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy18.817.015.8
Standard Smoking Cessation16.416.017.4

Carcinogen Exposure

Creatinine-adjusted NNAL (4-(methylnitrosamino)-1-(3)pyridyl-1-butanol)) exposure over 12 months. At Month 3, Month 6, and Month 12, participants provided a urine sample that was used to assess their level of urinary creatinine and NNAL. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventionpg/mg creatinine (Geometric Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy320.1186.0183.5
Standard Smoking Cessation279.0178.2190.4

Carcinogen Exposure (Continued Smokers Only)

Creatinine-adjusted NNAL (4-(methylnitrosamino)-1-(3)pyridyl-1-butanol)) exposure over 12 months. At Month 3, Month 6, and Month 12, participants provided a urine sample that was used to assess their level of urinary creatinine and NNAL. This analysis looks at NNAL among continuing smokers only. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventionpg/mg creatinine (Geometric Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy337.6217.1247.5
Standard Smoking Cessation314.6219.8257.0

Cotinine

Cotinine over 12 months, adjusted for creatinine. At Month 3, Month 6, and Month 12, participants provided a urine sample that was used to assess their level of urinary creatinine and cotinine. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventionng/mg creatinine (Geometric Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy3378.13342.32363.7
Standard Smoking Cessation2652.52390.72159.0

Cotinine (Continued Smokers Only)

Cotinine over 12 months, adjusted for creatinine. At Month 3, Month 6, and Month 12, participants provided a urine sample that was used to assess their level of urinary creatinine and cotinine. This analysis looks at NNAL among continuing smokers only. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventionng/mg creatinine (Geometric Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy3305.83502.22782.7
Standard Smoking Cessation2771.22850.72733.9

Quit Attempts

Number of self-reported quit attempts over one year. At Month 3 and Month 6, participants reported the number of quit attempts in the last 3 months. At Month 12, participants reported the number of quit attempts in the last 6 months. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventionnumber of quit attempts (Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy3.74.86.2
Standard Smoking Cessation4.64.55.7

Respiratory Symptoms

Respiratory symptoms as measured by the COPD Assessment Test (CAT) respiratory questionnaire. Participants completed this 8-item assessment at Month 3, Month 6, and Month 12. Scores range from 0 to 40, with higher levels indicating higher impact of COPD on well-being and daily life. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

,
Interventionunits on a scale (Mean)
Month 3Month 6Month 12
Extended Nicotine Replacement Therapy19.318.118.2
Standard Smoking Cessation17.817.917.5

Cardiac-related Hospital Visits

Number of cardiac-related hospital admissions and emergency room visits. Participants were asked how many times they had visited the ED or were admitted to the hospital for cardiac-related problems at Month 3, Month 6, and Month 12. (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

InterventionParticipants (Count of Participants)
Month 371962791Month 371962792Month 671962791Month 671962792Month 1271962791Month 1271962792
0 Visits2 or more Visits1 Visit
Standard Smoking Cessation181
Extended Nicotine Replacement Therapy185
Standard Smoking Cessation7
Extended Nicotine Replacement Therapy6
Standard Smoking Cessation1
Extended Nicotine Replacement Therapy0
Standard Smoking Cessation171
Extended Nicotine Replacement Therapy180
Standard Smoking Cessation10
Extended Nicotine Replacement Therapy4
Standard Smoking Cessation0
Extended Nicotine Replacement Therapy1
Standard Smoking Cessation175
Extended Nicotine Replacement Therapy167
Standard Smoking Cessation8
Extended Nicotine Replacement Therapy12
Standard Smoking Cessation2
Extended Nicotine Replacement Therapy3

Respiratory-related Hospital Visits

Number of respiratory-related hospital admissions and emergency room visits. Participants were asked how many times they had visited the ED or were admitted to the hospital for respiratory-related problems at Month 3, Month 6, and Month 12 (NCT02148445)
Timeframe: Month 3, Month 6, Month 12

InterventionParticipants (Count of Participants)
Month 371962791Month 371962792Month 671962792Month 671962791Month 1271962791Month 1271962792
0 Visits1 Visit2 or more Visits
Standard Smoking Cessation176
Extended Nicotine Replacement Therapy169
Standard Smoking Cessation11
Extended Nicotine Replacement Therapy15
Standard Smoking Cessation2
Standard Smoking Cessation152
Extended Nicotine Replacement Therapy154
Standard Smoking Cessation22
Extended Nicotine Replacement Therapy24
Standard Smoking Cessation7
Extended Nicotine Replacement Therapy7
Standard Smoking Cessation157
Extended Nicotine Replacement Therapy153
Standard Smoking Cessation18
Extended Nicotine Replacement Therapy20
Standard Smoking Cessation10
Extended Nicotine Replacement Therapy10

Disease Progression at Baseline With Decline in FEV1 Greater Than 10%

Participants with progressive disease at baseline with decline in FEV1 greater than 10% (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients2
Inhaled Cyclosporine in Lung Transplant Recipients0

Disease Progression at Baseline With Stablization of FEV1

Participants with progressive disease at baseline with stablization of FEV1 (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients2
Inhaled Cyclosporine in Lung Transplant Recipients0

Disease Stability at Baseline With Stablization in FEV1 and Greater Than 25% Decline in Systemic Immunosuppression

Participants with stable disease at baseline with stablization in FEV1 and greater than 25% decline in systemic immunosuppression (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients3
Inhaled Cyclosporine in Lung Transplant Recipients0

Overall Non-response to Treatment

Participants who did not respond to treatment with cyclosporine inhalation solution (CIS) (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients7
Inhaled Cyclosporine in Lung Transplant Recipients2

Overall Response to Treatment Based on Positive Response to Cyclosporine Inhalation Solution (CIS)

Participants who responded to treatment with cyclosporine inhalation solution (CIS) (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients9
Inhaled Cyclosporine in Lung Transplant Recipients0

Stable Disease at Baseline With Stablization of FEV1 and no Change or Increase in Systemic Immunosuppresion

Participants with stable disease at baseline with stablization of FEV1 and no change or increase in systemic immunosuppresion (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients4
Inhaled Cyclosporine in Lung Transplant Recipients2

Stable or Progressive Disease at Baseline With Greater Than 20% of Decline in FEV1

Participants with stable or progressive disease at baseline with greater than 20% of decline in FEV1 (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients1
Inhaled Cyclosporine in Lung Transplant Recipients0

Stable or Progressive Disease at Baseline With Improvement of FEV1

Participants with stable or progressive disease at baseline with improvement of FEV1 (NCT01287078)
Timeframe: 18 weeks

InterventionParticipants (Count of Participants)
Inhaled Cyclosporine in HSCT Recipients4
Inhaled Cyclosporine in Lung Transplant Recipients0

Reviews

10 reviews available for carbon monoxide and Chronic Illness

ArticleYear
[Early diagnosis of connective tissue disease-related pulmonary hypertension].
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2009, Volume: 32, Issue:6

    Topics: Biomarkers; Carbon Monoxide; Chronic Disease; Connective Tissue Diseases; Early Diagnosis; Echocardi

2009
Poisons in the air: a cause of chronic disease in children.
    Journal of toxicology. Clinical toxicology, 2002, Volume: 40, Issue:4

    Topics: Air Pollutants; Carbon Monoxide; Child; Child Welfare; Chronic Disease; Female; Fetus; Humans; Nitro

2002
Exhaled breath measures of inflammation: are they useful in neonatal chronic lung disease?
    Archives of disease in childhood. Fetal and neonatal edition, 2005, Volume: 90, Issue:1

    Topics: Biomarkers; Breath Tests; Carbon Monoxide; Chronic Disease; Humans; Hydrocarbons; Infant, Newborn; I

2005
The hyperdynamic circulation of chronic liver diseases: from the patient to the molecule.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:2 Suppl 1

    Topics: Adrenomedullin; Animals; Biological Factors; Blood Pressure; Cannabinoid Receptor Modulators; Carbon

2006
[Clinical repercussions of exposure to atmospheric pollution].
    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2006, Volume: 32 Suppl 2

    Topics: Air Pollutants; Air Pollution; Brazil; Carbon Monoxide; Cardiovascular Diseases; Chronic Disease; En

2006
Carbon monoxide and carboxyhemoglobin.
    Advances in pediatrics, 1995, Volume: 42

    Topics: Acute Disease; Adult; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Child; Chronic

1995
Air pollution: its effects on health and respiratory disease--a review.
    Annals of allergy, 1977, Volume: 39, Issue:4

    Topics: Air Pollution; Asthma; Bronchitis; Carbon Monoxide; Chronic Disease; Hydrocarbons; Meteorological Co

1977
[Chronic carbon monoxide poisoning].
    Medizinische Klinik, 1975, Mar-14, Volume: 70, Issue:11

    Topics: Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Chronic Disease; Environmental Exposu

1975
[Demonstrable effects of carbon monoxide on the human organism].
    Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete, 1972, Volume: 18, Issue:12

    Topics: Carbon Dioxide; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Cardiovascular System

1972
Arterial oxygenation and pulmonary hemodynamics in patients with chronic airways obstruction.
    The American review of respiratory disease, 1974, Volume: 110, Issue:6 Pt 2

    Topics: Blood Pressure; Carbon Monoxide; Cardiac Output; Chronic Disease; Hemodynamics; Humans; Hypertension

1974

Trials

7 trials available for carbon monoxide and Chronic Illness

ArticleYear
Effect of Long-term Nicotine Replacement Therapy vs Standard Smoking Cessation for Smokers With Chronic Lung Disease: A Randomized Clinical Trial.
    JAMA network open, 2018, 09-07, Volume: 1, Issue:5

    Topics: Adult; Aged; Carbon Monoxide; Chronic Disease; Counseling; Female; Humans; Lung Diseases; Male; Midd

2018
Prediction of functional recovery after revascularization in patients with chronic ischemic myocardial dysfunction: perfusable tissue index by positron emission tomography and contrast-enhanced MRI comparison study.
    Nuclear medicine communications, 2011, Volume: 32, Issue:12

    Topics: Aged; Antimetabolites; Carbon Monoxide; Chronic Disease; Contrast Media; Female; Humans; Magnetic Re

2011
Does lung diffusion impairment affect exercise capacity in patients with heart failure?
    Heart (British Cardiac Society), 2002, Volume: 88, Issue:5

    Topics: Blood Gas Analysis; Carbon Monoxide; Cardiac Output, Low; Chronic Disease; Exercise Test; Exercise T

2002
Use of breath carbon monoxide measurements to assess erythrocyte survival in subjects with chronic diseases.
    American journal of hematology, 2006, Volume: 81, Issue:6

    Topics: Aged; Aged, 80 and over; Anemia; Arthritis, Rheumatoid; Bone Marrow; Breath Tests; Carbon Monoxide;

2006
Increased plasma brain-derived neurotrophic factor levels in chronic smokers following unaided smoking cessation.
    Neuroscience letters, 2007, Aug-09, Volume: 423, Issue:1

    Topics: Adult; Brain-Derived Neurotrophic Factor; Carbon Monoxide; Chronic Disease; Enzyme-Linked Immunosorb

2007
Cocaine effects on digital blood flow and diffusing capacity for carbon monoxide among chronic cocaine users.
    The American journal of medicine, 1997, Volume: 102, Issue:3

    Topics: Adult; Carbon Monoxide; Chronic Disease; Cocaine; Dose-Response Relationship, Drug; Double-Blind Met

1997
[Measurement of global diffusion capacity for CO, membrane diffusion capacity for CO and capillary blood volume in patients with bronchial emphysema after fominoben HCl. Short- and long-time trials (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:2

    Topics: Adult; Blood Volume; Capillaries; Carbon Monoxide; Cell Membrane; Chronic Disease; Clinical Trials a

1979

Other Studies

97 other studies available for carbon monoxide and Chronic Illness

ArticleYear
Estimated plasma volume status is a modest predictor of true plasma volume excess in compensated chronic heart failure patients.
    Scientific reports, 2021, 12-20, Volume: 11, Issue:1

    Topics: Aged; Anthropometry; Area Under Curve; Carbon Monoxide; Cardiology; Chronic Disease; Cross-Sectional

2021
Clinically unrecognized plasma volume expansion predicts long-term all-cause-mortality in chronic heart failure.
    Clinical cardiology, 2022, Volume: 45, Issue:10

    Topics: Carbon Monoxide; Chronic Disease; Diuretics; Female; Heart Failure; Humans; Pilot Projects; Plasma V

2022
Use of mycophenolate mofetil and azathioprine for the treatment of chronic hypersensitivity pneumonitis-A single-centre experience.
    The clinical respiratory journal, 2019, Volume: 13, Issue:12

    Topics: Adrenal Cortex Hormones; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Carbon Monoxide; Chroni

2019
Lung health and exposure to air pollution in Malawian children (CAPS): a cross-sectional study.
    Thorax, 2019, Volume: 74, Issue:11

    Topics: Air Pollution, Indoor; Body Height; Body Weight; Carbon Monoxide; Carboxyhemoglobin; Child; Chronic

2019
Modification of the CO-rebreathing method to determine haemoglobin mass and blood volume in patients suffering from chronic mountain sickness.
    Experimental physiology, 2019, Volume: 104, Issue:12

    Topics: Administration, Inhalation; Adult; Aged; Altitude Sickness; Blood Volume; Carbon Monoxide; Chronic D

2019
Impact of Azathioprine use in chronic hypersensitivity pneumonitis patients.
    Pulmonary pharmacology & therapeutics, 2020, Volume: 60

    Topics: Adult; Aged; Aged, 80 and over; Alveolitis, Extrinsic Allergic; Azathioprine; Carbon Monoxide; Chron

2020
Use of leflunomide in patients with chronic hypersensitivity pneumonitis.
    BMC pulmonary medicine, 2020, Jul-21, Volume: 20, Issue:1

    Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Carbon Monoxide; Chronic Disease; Female; Humans; Immun

2020
Prevalence and determinants of hepatopulmonary syndrome in decompensated chronic liver disease.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2020, Volume: 39, Issue:4

    Topics: Carbon Monoxide; Chronic Disease; Cross-Sectional Studies; Female; Hepatic Encephalopathy; Hepatopul

2020
Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2019, Volume: 38, Issue:2

    Topics: Aged; Carbon Monoxide; Chronic Disease; Female; Follow-Up Studies; Forced Expiratory Volume; Humans;

2019
Chronic eosinophilic pneumonia with persistent decreased diffusing capacity for carbon monoxide.
    BMJ case reports, 2013, Feb-15, Volume: 2013

    Topics: Adolescent; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Chronic Disease; Diagnosis, Differential;

2013
Chronic Migraineurs Form Carboxyhemefibrinogen and Iron-Bound Fibrinogen.
    CNS & neurological disorders drug targets, 2015, Volume: 14, Issue:8

    Topics: Anticoagulants; Blood Coagulation; Body Mass Index; Carbon Monoxide; Chronic Disease; Citrates; Fema

2015
Use of Mycophenolate Mofetil or Azathioprine for the Management of Chronic Hypersensitivity Pneumonitis.
    Chest, 2017, Volume: 151, Issue:3

    Topics: Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Carbon Monoxide; Chronic Disease; Female; Glucoc

2017
Chronic carbon monoxide exposure increases electrocardiographic P-wave and QT dispersion.
    Inhalation toxicology, 2008, Volume: 20, Issue:9

    Topics: Adult; Air Pollutants, Occupational; Arrhythmias, Cardiac; Blood Pressure; Body Mass Index; Carbon M

2008
Does exercise have deleterious consequences for the lungs of patients with chronic heart failure?
    Respiratory medicine, 2009, Volume: 103, Issue:3

    Topics: Aged; Analysis of Variance; Carbon Monoxide; Case-Control Studies; Chronic Disease; Contraindication

2009
Low-dose carbon monoxide inhibits progressive chronic allograft nephropathy and restores renal allograft function.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:1

    Topics: Animals; Atrophy; Carbon Monoxide; Chronic Disease; Disease Models, Animal; Disease Progression; Dos

2009
Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart.
    Circulation, 2010, May-04, Volume: 121, Issue:17

    Topics: Animals; Apoptosis; Carbon Monoxide; Cardiotonic Agents; Chronic Disease; Fibrosis; Gene Expression;

2010
[The effect of chimonin on collagen metabolism of pulmonary arterioles in chronic hypoxic rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2010, Volume: 26, Issue:2

    Topics: Animals; Arterioles; Carbon Monoxide; Chronic Disease; Collagen Type I; Collagen Type III; Drugs, Ch

2010
Low-level exposure to carbon monoxide.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2012, Volume: 62, Issue:601

    Topics: Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Environmental Exposure; Humans

2012
Pulmonary gas exchange abnormalities in liver transplant candidates.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2002, Volume: 8, Issue:9

    Topics: Adolescent; Adult; Aged; Arteries; Carbon Dioxide; Carbon Monoxide; Chronic Disease; Female; Humans;

2002
Gene transfer of heme oxygenase-1 and carbon monoxide delivery inhibit chronic rejection.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2002, Volume: 2, Issue:7

    Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Chlorocebus aethiops; Chronic Disease; COS Cells; Gene

2002
Effect of hypobaric hypoxia on blood gases in patients with restrictive lung disease.
    The European respiratory journal, 2002, Volume: 20, Issue:2

    Topics: Adult; Aged; Atmospheric Pressure; Blood Gas Analysis; Carbon Dioxide; Carbon Monoxide; Chronic Dise

2002
[Vestibular chronaxy in experimental chronic poisoning by carbon monoxide in the rabbit; comparison with chronic poisoning in man].
    Revue de pathologie generale et de physiologie clinique, 1955, Volume: 55, Issue:670

    Topics: Animals; Carbon Monoxide; Carbon Monoxide Poisoning; Chronaxy; Chronic Disease; Ear, Inner; Humans;

1955
[Dangers of fuel in the winter; case of chronic poisoning caused by carbon monoxide].
    Revue medicale de la Suisse romande, 1956, Volume: 76, Issue:1

    Topics: Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Humans; Poisoning; Seasons

1956
[Chronic & mass poisoning by carbon monoxide].
    Concours medical, 1957, Nov-02, Volume: 79, Issue:44

    Topics: Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Humans

1957
[The pulmonary diffusion of CO in chronic lung diseases].
    Minerva medica, 1961, Dec-08, Volume: 52

    Topics: Carbon Monoxide; Chronic Disease; Humans; Lung Diseases; Pulmonary Diffusing Capacity; Respiration

1961
[DETERMINATION OF THE DIFFUSION CAPACITY OF THE LUNG WITH AID OF CARBON MONOXIDE (SINGLE RESPIRATION METHOD) IN CHRONIC LUNG DISEASES].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1964, May-25, Volume: 19

    Topics: Carbon Monoxide; Chronic Disease; Humans; Lung Diseases; Pneumonectomy; Respiratory Function Tests

1964
Atypical parkinsonism and motor neuron syndrome in a Biosphere 2 participant: a possible complication of chronic hypoxia and carbon monoxide toxicity?
    Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:4

    Topics: Aged; Brain; Carbon Monoxide; Chronic Disease; Gait; Humans; Hypoxia; Magnetic Resonance Imaging; Ma

2004
HLA-DR2 predicts susceptibility and disease chronicity in Irish sarcoidosis patients.
    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2004, Volume: 21, Issue:3

    Topics: Adult; Biomarkers; Carbon Monoxide; Case-Control Studies; Chronic Disease; Female; Follow-Up Studies

2004
Continuous inhalation of carbon monoxide attenuates hypoxic pulmonary hypertension development presumably through activation of BKCa channels.
    Cardiovascular research, 2005, Feb-15, Volume: 65, Issue:3

    Topics: Animals; Calcium; Carbon Monoxide; Cell Polarity; Chronic Disease; Drug Administration Schedule; Hem

2005
Delayed contrast enhancement and perfusable tissue index in hypertrophic cardiomyopathy: comparison between cardiac MRI and PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:6

    Topics: Adult; Aged; Carbon Monoxide; Cardiomyopathy, Hypertrophic; Case-Control Studies; Chronic Disease; F

2005
Mechanisms of heme oxygenase-1-mediated cardiac and pulmonary vascular protection in chronic hypoxia: roles of carbon monoxide and bilirubin.
    Chest, 2005, Volume: 128, Issue:6 Suppl

    Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Chronic Disease; Heme Oxygenase-1; Hypertension, P

2005
Smoking cessation advice for patients with chronic periodontitis.
    British dental journal, 2006, Mar-11, Volume: 200, Issue:5

    Topics: Adult; Breath Tests; Bupropion; Carbon Monoxide; Central Nervous System Stimulants; Chronic Disease;

2006
Socioeconomic status, particulate air pollution, and daily mortality: differential exposure or differential susceptibility.
    American journal of industrial medicine, 2007, Volume: 50, Issue:3

    Topics: Adult; Air Pollutants; Air Pollution; Carbon Monoxide; Chronic Disease; Disease Susceptibility; Envi

2007
End-tidal carbon monoxide measurements in infant respiratory distress syndrome.
    Acta paediatrica (Oslo, Norway : 1992), 2006, Volume: 95, Issue:9

    Topics: Breath Tests; Carbon Monoxide; Chronic Disease; Humans; Infant, Newborn; Lung Diseases; Prognosis; R

2006
Chronic GVHD and pretransplantation abnormalities in pulmonary function are the main determinants predicting worsening pulmonary function in long-term survivors after stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Carbon Monoxide; Child; Chronic Disease; Comorbidity; Disease Progression; Female

2006
Light cigarette smoking impairs coronary microvascular functions as severely as smoking regular cigarettes.
    Heart (British Cardiac Society), 2007, Volume: 93, Issue:10

    Topics: Acute Disease; Adult; Blood Flow Velocity; Carbon Monoxide; Chronic Disease; Coronary Circulation; C

2007
Carbon monoxide diffusing studies in the clinical evaluation of chronic lung diseases.
    Diseases of the chest, 1967, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Carbon Dioxide; Carbon Monoxide; Chronic Disease; Femal

1967
Hypoxic insomnia: effects of carbon monoxide and acclimatization.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 57, Issue:6

    Topics: Acclimatization; Altitude; Animals; Body Weight; Carbon Monoxide; Chronic Disease; Hemoglobins; Huma

1984
Carbon monoxide and exercise tolerance in chronic bronchitis and emphysema.
    British medical journal (Clinical research ed.), 1981, Oct-03, Volume: 283, Issue:6296

    Topics: Bronchitis; Carbon Monoxide; Carboxyhemoglobin; Chronic Disease; Emphysema; Female; Humans; Male; Ph

1981
Hemodynamic and metabolic effects of chronic carbon monoxide exposure in cynomolgus monkeys (Macaca fascicularis).
    Journal of medical primatology, 1981, Volume: 10, Issue:4-5

    Topics: Animals; Carbon Dioxide; Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Female; Hemody

1981
[Chronic carbon monoxide poisoning].
    Nederlands tijdschrift voor geneeskunde, 1982, Jan-09, Volume: 126, Issue:2

    Topics: Adult; Air Pollution; Carbon Monoxide; Carbon Monoxide Poisoning; Child; Child, Preschool; Chronic D

1982
[Subacute and chronic occupational carbon monoxide poisoning].
    La Revue du praticien, 1982, Mar-21, Volume: 32, Issue:17

    Topics: Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Humans; Occupational Diseases

1982
Carbon monoxide in chronic uraemia related to erythropoietin treatment and smoking habits.
    Scandinavian journal of urology and nephrology, 1995, Volume: 29, Issue:1

    Topics: Adult; Aged; Carbon Monoxide; Chronic Disease; Erythropoietin; Female; Humans; Longitudinal Studies;

1995
[Gas exchange during spontaneous and controlled ventilation in obese subjects with chronic bronchitis. Value of normalized CO intake].
    Revue de pneumologie clinique, 1993, Volume: 49, Issue:5

    Topics: Adult; Aged; Blood Gas Analysis; Bronchitis; Carbon Monoxide; Chronic Disease; Female; Humans; Male;

1993
Chronic carbon monoxide poisoning.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:1

    Topics: Adult; Brain Damage, Chronic; Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Diagnosis

1994
The diversity of the effects of sulfur mustard gas inhalation on respiratory system 10 years after a single, heavy exposure: analysis of 197 cases.
    Chest, 1997, Volume: 112, Issue:3

    Topics: Adult; Aged; Airway Obstruction; Asthma; Biopsy; Bronchiectasis; Bronchitis; Bronchoscopy; Carbon Mo

1997
Cerebral hematocrit decreases with hemodynamic compromise in carotid artery occlusion: a PET study.
    Stroke, 1998, Volume: 29, Issue:1

    Topics: Aged; Brain; Brain Ischemia; Carbon Monoxide; Carotid Artery Diseases; Carotid Artery, Internal; Cer

1998
Respiratory symptoms in a susceptible population due to burning of agricultural residue.
    Chest, 1998, Volume: 113, Issue:2

    Topics: Adult; Agriculture; Air Pollutants; Air Pollution; Airway Obstruction; Asthma; Bronchial Hyperreacti

1998
Reduction of diffusion capacity for carbon monoxide in diabetic patients.
    Chest, 1998, Volume: 114, Issue:4

    Topics: Adult; Carbon Monoxide; Chromatography, Ion Exchange; Chronic Disease; Diabetes Complications; Diabe

1998
Body position, membrane diffusing capacity and pulmonary capillary blood volume in chronic bronchitis and pulmonary emphysema.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1999, Volume: 62, Issue:4

    Topics: Aged; Blood Volume; Bronchitis; Carbon Monoxide; Chronic Disease; Humans; Lung; Middle Aged; Posture

1999
Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis.
    The American journal of medicine, 1999, Volume: 106, Issue:6

    Topics: Adult; Asthma; Bronchitis; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Case-Control Studies; Chem

1999
Acute smoking increases ST depression in humans during general anesthesia.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:4

    Topics: Acute Disease; Adult; Anesthesia, General; Anesthetics, Inhalation; Blood Pressure; Carbon Monoxide;

1999
Carotid body NO-CO interaction and chronic hypoxia.
    Advances in experimental medicine and biology, 2000, Volume: 475

    Topics: Animals; Carbon Monoxide; Carotid Body; Chemoreceptor Cells; Chronic Disease; Heme Oxygenase (Decycl

2000
Renal vasodilatory influence of endogenous carbon monoxide in chronically hypoxic rats.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Carbon Monoxide; Chronic Disease; Consciousness; Enzyme Inhibitors; Heme Oxygenase (Decycli

2000
[Pulmonary circulatory amputation in chronic respiratory insufficiency. Simple, anodyne, and fast evaluation].
    Revue de pneumologie clinique, 2001, Volume: 57, Issue:6

    Topics: Aged; Carbon Dioxide; Carbon Monoxide; Chronic Disease; Female; Humans; Hypoxia; Lung; Male; Middle

2001
[Risk of chronic carbon monoxide poisoning in automobile garages. Results of a study in the Lausanne region].
    Schweizerische medizinische Wochenschrift, 1975, Jan-11, Volume: 105, Issue:2

    Topics: Air Pollution; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Chronic Disease; Envir

1975
The oxyhemoglobin dissociation curve in acute disease.
    The Surgical clinics of North America, 1975, Volume: 55, Issue:3

    Topics: Acute Disease; Adenosine Triphosphate; Altitude; Blood Gas Analysis; Blood Preservation; Carbon Diox

1975
Dco at various breath-holding times: comparison in patients with chronic bronchial asthma and emphysema.
    Respiration; international review of thoracic diseases, 1979, Volume: 37, Issue:4

    Topics: Adult; Asthma; Carbon Monoxide; Chronic Disease; Humans; Lung; Middle Aged; Pulmonary Diffusing Capa

1979
Extreme but asymptomatic carboxyhemoglobinemia and chronic lung disease.
    JAMA, 1978, Jun-16, Volume: 239, Issue:24

    Topics: Aged; Carbon Monoxide; Carboxyhemoglobin; Chronic Disease; Hemoglobins; Humans; Hypoxia; Lung Diseas

1978
Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis.
    The Journal of biological chemistry, 1979, Feb-10, Volume: 254, Issue:3

    Topics: Anemia, Hemolytic, Congenital; Animals; Carbon Monoxide; Chronic Disease; Cytochrome P-450 Enzyme Sy

1979
Air pollution and COPD.
    Postgraduate medicine, 1977, Volume: 62, Issue:1

    Topics: Air Pollutants; Cadmium; Carbon Monoxide; Chlorine; Chronic Disease; Humans; Lung; Lung Diseases, Ob

1977
Secondary polycythaemia in chronic respiratory insufficiency.
    Thorax, 1977, Volume: 32, Issue:3

    Topics: Carbon Monoxide; Chronic Disease; Diphosphoglyceric Acids; Erythrocytes; Hemoglobins; Humans; Oxygen

1977
[Pulmonary diffusing capacity for carbon monoxide during rest and following exertion in chronic obstructive ephysema].
    Wiener medizinische Wochenschrift (1946), 1977, Jun-20, Volume: 127, Issue:12

    Topics: Carbon Monoxide; Chronic Disease; Emphysema; Humans; Physical Exertion; Pulmonary Alveoli; Pulmonary

1977
Pulmonary diffusing capacity measured at multiple intervals during a single exhalation in man.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1977, Volume: 43, Issue:4

    Topics: Adult; Asthma; Blood Volume; Carbon Monoxide; Chronic Disease; Humans; Lung Diseases, Obstructive; M

1977
Clinical relevance of the flow rate response to low density gas breathing in asthmatics.
    The American review of respiratory disease, 1975, Volume: 111, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Airway Obstruction; Asthma; Bronchodilator Agents; Carbon Mo

1975
[Cellular immunity indices in combined chronic exposure to stress and low concentrations of carbon monoxide (II). Experimental research].
    Gigiena truda i professional'nye zabolevaniia, 1992, Issue:8

    Topics: Animals; Carbon Monoxide; Chronic Disease; Dose-Response Relationship, Drug; Immunity, Cellular; Imm

1992
Composition of popular tobacco products in Thailand, and its relevance to disease prevention.
    Preventive medicine, 1991, Volume: 20, Issue:6

    Topics: Advertising; Carbon Monoxide; Chronic Disease; Coal Tar; Evaluation Studies as Topic; Filtration; Hu

1991
Determination of lung capillary blood volume and membrane diffusing capacity in patients with COLD using the NO-CO method.
    The European respiratory journal, 1990, Volume: 3, Issue:3

    Topics: Adult; Aged; Blood Volume Determination; Capillary Permeability; Carbon Monoxide; Chronic Disease; F

1990
A longitudinal study of symptoms and respiratory function tests in iron miners.
    European journal of respiratory diseases, 1986, Volume: 69, Issue:5

    Topics: Adult; Asthma; Bronchitis; Carbon Monoxide; Chronic Disease; France; Health; Health Status; Humans;

1986
Smoking cessation in chronically ill medical patients.
    Journal of clinical psychology, 1985, Volume: 41, Issue:4

    Topics: Behavior Therapy; Carbon Monoxide; Chronic Disease; Coronary Disease; Feedback; Follow-Up Studies; H

1985
[Normal values of Hb-CO saturation of blood].
    Schweizerische medizinische Wochenschrift, 1970, Apr-25, Volume: 100, Issue:17

    Topics: Adult; Age Factors; Agriculture; Carbon Monoxide; Chronic Disease; Environmental Exposure; Exercise

1970
Public health aspects of air pollution from diesel vehicles.
    Public health, 1974, Volume: 88, Issue:4

    Topics: Air Pollution; Carbon; Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Female; Fuel Oil

1974
Respiratory disturbances in chronic bronchitis.
    Scandinavian journal of respiratory diseases, 1974, Volume: 55, Issue:4

    Topics: Acid-Base Equilibrium; Adult; Age Factors; Blood; Blood Pressure; Blood Volume; Bronchitis; Carbon D

1974
The use of expiratory forced flows for determining response to bronchodilator therapy.
    Chest, 1972, Volume: 62, Issue:5

    Topics: Airway Resistance; Bronchodilator Agents; Carbon Monoxide; Chronic Disease; Humans; Isoproterenol; L

1972
Oxyhemoglobin affinity in bronchial asthma: chronic stable state, acute, and status asthmaticus.
    Chest, 1972, Volume: 62, Issue:6

    Topics: Acute Disease; Adult; Asthma; Carbon Dioxide; Carbon Monoxide; Chronic Disease; Erythrocytes; Female

1972
[Patterns of lung function in moderate chronic bronchitis and allergic asthma].
    Pneumonologie. Pneumonology, 1972, Volume: 148, Issue:1

    Topics: Adult; Air; Airway Resistance; Asthma; Bronchitis; Carbon Monoxide; Chronic Disease; Humans; Lung; M

1972
[Active-smoking and passive-smoking].
    Fortschritte der Medizin, 1972, Dec-07, Volume: 90, Issue:34

    Topics: Adolescent; Adult; Air Pollution; Bronchial Neoplasms; Bronchitis; Carbon Monoxide; Child; Chronic D

1972
Regulation of respiration during oxygen breathing in chronic obstructive lung disease.
    The American review of respiratory disease, 1973, Volume: 108, Issue:2

    Topics: Acidosis; Airway Resistance; Arteries; Bicarbonates; Carbon Dioxide; Carbon Monoxide; Chronic Diseas

1973
Pulmonary function in chronic alcoholism.
    The American review of respiratory disease, 1973, Volume: 108, Issue:4

    Topics: Adult; Alcoholism; Carbon Monoxide; Chronic Disease; Female; Humans; Lung Compliance; Lung Diseases,

1973
[Steady-state CO pulmonary diffusing capacity in chronic pulmonary diseases].
    Nihon Kyobu Shikkan Gakkai zasshi, 1973, Volume: 11, Issue:7

    Topics: Adolescent; Adult; Carbon Monoxide; Chronic Disease; Female; Humans; Lung Diseases; Male; Middle Age

1973
[Frequency of chronic bronchitis in different socio-occupational groups. II. Workers of a steel factory (author's transl)].
    Respiration; international review of thoracic diseases, 1974, Volume: 31, Issue:5

    Topics: Adult; Alloys; Bronchitis; Carbon Monoxide; Chronic Disease; Environmental Exposure; France; Humans;

1974
Membrane diffusing capacity and pulmonary capillary blood volume in chronic obstructive lung disease.
    The American review of respiratory disease, 1972, Volume: 105, Issue:6

    Topics: Blood Volume; Bronchitis; Capillaries; Carbon Monoxide; Chronic Disease; Female; Hemoglobins; Humans

1972
Lung function studies in asbestos workers.
    British journal of diseases of the chest, 1972, Volume: 66, Issue:2

    Topics: Adult; Aged; Airway Obstruction; Asbestosis; Bronchitis; Carbon Monoxide; Chronic Disease; Female; H

1972
[Chronic carbon monoxide poisoning].
    Archives des maladies professionnelles de medecine du travail et de securite sociale, 1972, Volume: 23, Issue:3

    Topics: Air Pollution; Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Humans; Occupational Dis

1972
[Pulmonary diffusing capacity and regional pulmonary function].
    Iryo, 1971, Volume: 25, Issue:7

    Topics: Adolescent; Adult; Aged; Asthma; Carbon Monoxide; Chronic Disease; Female; Heart Septal Defects, Atr

1971
[Functional respiratory investigations. Ductance of CO (carbon monoxide): global estimation of pulmonary exchanger, omitting blood tests].
    La Presse medicale, 1971, Oct-02, Volume: 79, Issue:41

    Topics: Adult; Blood Gas Analysis; Bronchitis; Carbon Monoxide; Chronic Disease; Humans; Infant, Newborn; Lu

1971
The relative importance of clinical, radiological and pulmonary function variables in evaluating asbestosis and chronic obstructive airway disease in asbestos workers.
    Clinical science, 1971, Volume: 41, Issue:6

    Topics: Adult; Asbestosis; Carbon Monoxide; Chronic Disease; Cough; Diagnosis, Differential; Humans; Lung Di

1971
Pulmonary gas transport characterization by a dynamic model.
    Respiration physiology, 1971, Volume: 12, Issue:3

    Topics: Adult; Aged; Carbon Monoxide; Chronic Disease; Humans; Lung Diseases, Obstructive; Middle Aged; Mode

1971
Relation between single-breath diffusing capacity and arterial blood gases in chronic obstructive lung disease.
    Scandinavian journal of respiratory diseases, 1968, Volume: 49, Issue:2

    Topics: Adult; Aged; Carbon Monoxide; Chronic Disease; Diffusion; Female; Granuloma; Humans; Hypoxia; Lung D

1968
On the prediction of pulmonary diffusing capacity with a steady state carbon monoxide method in chronic lung diseases.
    Scandinavian journal of clinical and laboratory investigation, 1969, Volume: 24, Issue:4

    Topics: Adult; Aged; Carbon Monoxide; Chronic Disease; Diffusion; Female; Heart Rate; Humans; Lung Diseases;

1969
A comparison of pulmonary function in bronchial asthma and chronic obstructive bronchitis.
    Thorax, 1970, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Asthma; Bronchitis; Carbon Dioxide; Carbon Monoxide; Child; Chronic Disease

1970
Relation between rebreathing CO-diffusing capacity of the lung and unequal ventilation.
    Scandinavian journal of respiratory diseases, 1970, Volume: 51, Issue:1

    Topics: Adult; Aged; Carbon Dioxide; Carbon Monoxide; Chronic Disease; Diffusion; Female; Helium; Humans; Lu

1970
Ischemic retinopathy due to carbon monoxide poisoning.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1971, Volume: 86, Issue:2

    Topics: Carbon Monoxide; Carbon Monoxide Poisoning; Child; Chronic Disease; Environmental Exposure; Eye Dise

1971
Application of the single-breath method of total lung capacity measurement to the calculation of the carbon monoxide diffusing capacity.
    The American review of respiratory disease, 1968, Volume: 97, Issue:4

    Topics: Adult; Aged; Carbon Monoxide; Chronic Disease; Helium; Humans; Lung; Lung Diseases; Male; Methods; M

1968
Carbon monoxide and coronary heart disease.
    Annals of internal medicine, 1969, Volume: 71, Issue:1

    Topics: Adult; Arteriosclerosis; Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Coronary Disea

1969
[Demonstration of carbon monoxide in the diagnosis of CO poisoning].
    Deutsche medizinische Wochenschrift (1946), 1969, Aug-22, Volume: 94, Issue:34

    Topics: Air; Biological Transport; Carbon Dioxide; Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disea

1969
[Indirect determination of carbon monoxide in blood].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1966, Volume: 4, Issue:5

    Topics: Asthenia; Carbon Monoxide; Carbon Monoxide Poisoning; Chronic Disease; Headache; Hemoglobins; Humans

1966