Page last updated: 2024-10-16

carbon monoxide and Cerebral Ischemia

carbon monoxide has been researched along with Cerebral Ischemia in 30 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Research Excerpts

ExcerptRelevanceReference
"Carbon monoxide treatment has shown potent cytoprotective effects in ischemia/reperfusion injury."5.43Carbon Monoxide Improves Neurologic Outcomes by Mitochondrial Biogenesis after Global Cerebral Ischemia Induced by Cardiac Arrest in Rats. ( Chang, RM; Chen, MD; Fang, XS; Huang, ZT; Jiang, LY; Li, Y; Liu, YS; Wang, P; Wu, HD; Yao, L; Yu, T; Zhou, LL; Zhou, MG, 2016)
"Carbon monoxide (CO) is a gaseous second messenger produced when heme oxygenase enzymes catabolize heme."5.37Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia. ( Biswal, S; Cao, W; Doré, S; Wang, B, 2011)
"Pretreatment with pentobarbital Na (30 mg/kg, i."5.28Carbon monoxide (CO)-induced hypoxia in mice: evaluation as an experimental model of cerebral ischemia for drug screening. ( Hiramatsu, Y; Kato, Y; Koida, M; Muguruma, K; Nakamuta, H; Ogawa, Y; Yasuda, K, 1989)
"Carbon monoxide intoxication is the most prevalent cause of death from carbon monoxide poisoning."3.81Cerebrovascular ischaemia after carbon monoxide intoxication. ( Ak, A; Bayir, A; Degirmenci, S; Kara, H, 2015)
"We used a time-stratified case-crossover design to study the association between short-term exposure to UFPs, particulate matter <10 microm in diameter (PM(10)), nitrogen oxides (NO(x)) and carbon monoxide (CO) (measured at single background station) and hospital admissions for stroke in Copenhagen (2003-2006)."3.76Association between short-term exposure to ultrafine particles and hospital admissions for stroke in Copenhagen, Denmark. ( Andersen, KK; Andersen, ZJ; Ketzel, M; Loft, S; Olsen, TS; Raaschou-Nielsen, O, 2010)
"This study was aimed to evaluate the influence of an antagonist of heme oxygenase, zinc protoporphyrin IX (ZnPPIX), on the production of endogenous carbon monoxide (CO) and the secondary cerebral injury after subarachnoid hemorrhage (SAH)."3.73Zinc protoporphyrin aggravates cerebral ischemic injury following experimental subarachnoid hemorrhage. ( An, W; Li, WX; Sun, BL; Xia, ZL; Yang, MF; Ye, WJ; Zhao, T; Zheng, CB, 2006)
"These methods may predispose patients to cerebral ischemia."2.80Cerebral oximetry monitoring during sinus endoscopy. ( DeMaria, S; Evans, A; Fischer, GW; Govindaraj, S; Heller, JA; Lin, HM; Weiner, MM, 2015)
"Carbon monoxide (CO) is a gaseous transmitter that is known to be involved in several physiological processes, but surprisingly it is also becoming a promising molecule to treat several pathologies including stroke and cancer."2.52Carbon monoxide: A new player in the redox regulation of connexin hemichannels. ( Del Rio, R; Ezquer, F; Ezquer, M; González, C; León-Paravic, CG; Martínez, AD; Pupo, A; Retamal, MA, 2015)
"Carbon monoxide treatment has shown potent cytoprotective effects in ischemia/reperfusion injury."1.43Carbon Monoxide Improves Neurologic Outcomes by Mitochondrial Biogenesis after Global Cerebral Ischemia Induced by Cardiac Arrest in Rats. ( Chang, RM; Chen, MD; Fang, XS; Huang, ZT; Jiang, LY; Li, Y; Liu, YS; Wang, P; Wu, HD; Yao, L; Yu, T; Zhou, LL; Zhou, MG, 2016)
"Carbon monoxide (CO) is an accepted cytoprotective molecule."1.39Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway. ( Biermann, J; Buerkle, H; Goebel, U; Lagrèze, WA; Loop, T; Otterbein, LE; Romão, CC; Schallner, N, 2013)
"Carbon monoxide (CO) is a gaseous second messenger produced when heme oxygenase enzymes catabolize heme."1.37Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia. ( Biswal, S; Cao, W; Doré, S; Wang, B, 2011)
"The area of cerebral infarction was measured at three levels using video imaging methods."1.29Failure of iron chelators to protect against cerebral infarction in hypoxia-ischemia. ( Davis, J; Fridovich, I; MacMillan, V, 1993)
"Focal cerebral ischemia was induced in anesthetized macaque monkeys by unilateral middle cerebral artery occlusion."1.28Loss of cerebral regulation during cardiac output variations in focal cerebral ischemia. ( Archer, D; Keller, TS; Kindt, GW; Tranmer, BI, 1992)
"Pretreatment with pentobarbital Na (30 mg/kg, i."1.28Carbon monoxide (CO)-induced hypoxia in mice: evaluation as an experimental model of cerebral ischemia for drug screening. ( Hiramatsu, Y; Kato, Y; Koida, M; Muguruma, K; Nakamuta, H; Ogawa, Y; Yasuda, K, 1989)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's6 (20.00)18.2507
2000's3 (10.00)29.6817
2010's18 (60.00)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Xing, L1
Wang, B2
Li, J1
Guo, X1
Lu, X1
Chen, X1
Sun, H1
Sun, Z1
Luo, X1
Qi, S1
Qian, X1
Yang, Y1
Hu, W1
Chen, Y1
Chen, J1
Abuchowski, A1
Dong, H2
Yu, Y1
Yao, S1
Lu, Y1
Chen, Z1
Li, G1
Yao, Y1
Yao, X1
Wang, SL1
Zhang, Z1
Tian, Y1
Liu, H1
Zhao, Z1
Xiang, X1
Li, M1
Juan, J1
Song, J1
Cao, Y1
Wang, X1
Chen, L1
Wei, C1
Hu, Y1
Gao, P1
Wu, J1
Li, Y2
Yang, P1
Huang, Y2
Lu, S1
Xu, F1
Lin, HW1
Perez-Pinzon, M1
Schallner, N1
Romão, CC1
Biermann, J1
Lagrèze, WA1
Otterbein, LE1
Buerkle, H1
Loop, T1
Goebel, U1
Tong, L1
Cai, M1
Zhang, H1
Su, B1
Li, Z1
Sharp, FR1
Zhan, X1
Liu, DZ1
Heller, JA1
DeMaria, S1
Govindaraj, S1
Lin, HM1
Fischer, GW1
Evans, A1
Weiner, MM1
Kara, H2
Bayir, A1
Ak, A1
Degirmenci, S1
Lange, JH1
Cegolon, L1
Retamal, MA1
León-Paravic, CG1
Ezquer, M1
Ezquer, F1
Del Rio, R1
Pupo, A1
Martínez, AD1
González, C1
Wang, P1
Yao, L1
Zhou, LL1
Liu, YS1
Chen, MD1
Wu, HD1
Chang, RM1
Zhou, MG1
Fang, XS1
Yu, T1
Jiang, LY1
Huang, ZT1
Andersen, ZJ1
Olsen, TS1
Andersen, KK1
Loft, S1
Ketzel, M1
Raaschou-Nielsen, O1
Cao, W1
Biswal, S1
Doré, S1
Zhou, J1
Wu, PF1
Wang, F1
Chen, JG1
Sutherland, BA1
Harrison, JC1
Nair, SM1
Sammut, IA1
Hong, YC1
Lee, JT1
Kim, H1
Kwon, HJ1
Sun, BL1
An, W1
Xia, ZL1
Zheng, CB1
Li, WX1
Yang, MF1
Zhao, T1
Ye, WJ1
Imuta, N1
Hori, O1
Kitao, Y1
Tabata, Y1
Yoshimoto, T1
Matsuyama, T1
Ogawa, S1
Lahiri, S1
Iturriaga, R1
Mokashi, A1
Ray, DK1
Chugh, D1
MacMillan, V1
Fridovich, I1
Davis, J1
Tammela, O1
Yamauchi, H1
Fukuyama, H1
Nagahama, Y1
Katsumi, Y1
Okazawa, H1
Tranmer, BI1
Keller, TS1
Kindt, GW1
Archer, D1
Muguruma, K2
Nakamuta, H2
Tsuji, M1
Yanagita, K1
Koida, M2
Maeda, H1
Manno, K1
Narama, I1
Ogawa, Y2
Hiramatsu, Y2
Yasuda, K1
Kato, Y1

Reviews

5 reviews available for carbon monoxide and Cerebral Ischemia

ArticleYear
The role of fatty acids in the regulation of cerebral vascular function and neuroprotection in ischemia.
    CNS & neurological disorders drug targets, 2013, May-01, Volume: 12, Issue:3

    Topics: Arachidonic Acid; Brain; Brain Ischemia; Calcitonin Gene-Related Peptide; Carbon Monoxide; Cerebrova

2013
Heat shock proteins in the brain: role of Hsp70, Hsp 27, and HO-1 (Hsp32) and their therapeutic potential.
    Translational stroke research, 2013, Volume: 4, Issue:6

    Topics: Apoptosis; Biliverdine; Brain Ischemia; Carbon Monoxide; Cerebrum; Heat-Shock Proteins; Heme Oxygena

2013
Carbon monoxide: A new player in the redox regulation of connexin hemichannels.
    IUBMB life, 2015, Volume: 67, Issue:6

    Topics: Brain Ischemia; Carbon Monoxide; Cell Membrane; Connexins; Gap Junctions; Humans; Ion Channels; Nitr

2015
Targeting gaseous molecules to protect against cerebral ischaemic injury: mechanisms and prospects.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:6

    Topics: Animals; Brain Ischemia; Carbon Monoxide; Cytoprotection; Drug Delivery Systems; Gases; Humans; Hydr

2012
Inhalation gases or gaseous mediators as neuroprotectants for cerebral ischaemia.
    Current drug targets, 2013, Jan-01, Volume: 14, Issue:1

    Topics: Administration, Inhalation; Animals; Brain Ischemia; Carbon Monoxide; Clinical Trials as Topic; Drug

2013

Trials

1 trial available for carbon monoxide and Cerebral Ischemia

ArticleYear
Cerebral oximetry monitoring during sinus endoscopy.
    The Laryngoscope, 2015, Volume: 125, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Arterial Pressure; Brain Ischemia; Carbon Monoxide; Confidence In

2015

Other Studies

24 other studies available for carbon monoxide and Cerebral Ischemia

ArticleYear
A Fluorogenic ONOO
    Journal of the American Chemical Society, 2022, 02-09, Volume: 144, Issue:5

    Topics: Animals; Brain Ischemia; Carbon Monoxide; Cell Line; Fluorescent Dyes; Humans; Ischemic Stroke; Neur

2022
Short-term effect of fine particular matter on daily hospitalizations for ischemic stroke: A time-series study in Yancheng, China.
    Ecotoxicology and environmental safety, 2021, Jan-15, Volume: 208

    Topics: Adult; Air Pollutants; Air Pollution; Brain Ischemia; Carbon Monoxide; China; Environmental Exposure

2021
SANGUINATE (PEGylated Carboxyhemoglobin Bovine): Mechanism of Action and Clinical Update.
    Artificial organs, 2017, Volume: 41, Issue:4

    Topics: Anemia; Anemia, Sickle Cell; Animals; Blood Substitutes; Brain Ischemia; Carbon Monoxide; Carboxyhem

2017
Acute effects of air pollution on ischaemic stroke onset and deaths: a time-series study in Changzhou, China.
    BMJ open, 2018, 07-23, Volume: 8, Issue:7

    Topics: Adult; Age Distribution; Aged; Air Pollutants; Air Pollution; Brain Ischemia; Carbon Monoxide; China

2018
Association between ambient air pollution and daily hospital admissions for ischemic stroke: A nationwide time-series analysis.
    PLoS medicine, 2018, Volume: 15, Issue:10

    Topics: Adolescent; Adult; Aged; Air Pollutants; Air Pollution; Brain Ischemia; Carbon Monoxide; China; Citi

2018
Novel Role of Carbon Monoxide in Improving Neurological Outcome After Cardiac Arrest in Aged Rats: Involvement of Inducing Mitochondrial Autophagy.
    Journal of the American Heart Association, 2019, 05-07, Volume: 8, Issue:9

    Topics: Animals; Autophagy; Brain; Brain Ischemia; Carbon Monoxide; Disease Models, Animal; Heart Arrest; Ma

2019
Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Animals; Apoptosis; Brain Ischemia; Carbon Monoxide; Cell Line, Tumor; Coordination Complexes; Cycli

2013
Activation of K(2)P channel-TREK1 mediates the neuroprotection induced by sevoflurane preconditioning.
    British journal of anaesthesia, 2014, Volume: 113, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Carbon Monoxide; Cell Differentiation; Cell Hypoxia; Cell Survival;

2014
Cerebrovascular ischaemia after carbon monoxide intoxication.
    Singapore medical journal, 2015, Volume: 56, Issue:2

    Topics: Brain; Brain Ischemia; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Creatine Kinas

2015
Comment on: cerebrovascular ischaemia after carbon monoxide intoxication.
    Singapore medical journal, 2015, Volume: 56, Issue:3

    Topics: Brain Ischemia; Carbon Monoxide; Carbon Monoxide Poisoning; Humans; Male

2015
Author's reply: cerebrovascular ischaemia after carbon monoxide intoxication.
    Singapore medical journal, 2015, Volume: 56, Issue:3

    Topics: Brain Ischemia; Carbon Monoxide; Carbon Monoxide Poisoning; Humans; Male

2015
Carbon Monoxide Improves Neurologic Outcomes by Mitochondrial Biogenesis after Global Cerebral Ischemia Induced by Cardiac Arrest in Rats.
    International journal of biological sciences, 2016, Volume: 12, Issue:8

    Topics: Animals; Brain; Brain Ischemia; Carbon Monoxide; DNA-Binding Proteins; GA-Binding Protein Transcript

2016
Association between short-term exposure to ultrafine particles and hospital admissions for stroke in Copenhagen, Denmark.
    European heart journal, 2010, Volume: 31, Issue:16

    Topics: Aged; Air Pollutants; Atrial Fibrillation; Brain Ischemia; Carbon Monoxide; Cerebral Hemorrhage; Cro

2010
Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia.
    Stroke, 2011, Volume: 42, Issue:9

    Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Animals; Antimetabolites; Brai

2011
Air pollution: a new risk factor in ischemic stroke mortality.
    Stroke, 2002, Volume: 33, Issue:9

    Topics: Air Pollution; Brain Ischemia; Carbon Monoxide; Cerebral Hemorrhage; Comorbidity; Environmental Moni

2002
Zinc protoporphyrin aggravates cerebral ischemic injury following experimental subarachnoid hemorrhage.
    Clinical hemorheology and microcirculation, 2006, Volume: 34, Issue:1-2

    Topics: Animals; Brain Ischemia; Carbon Monoxide; Cyclic GMP; Heme Oxygenase (Decyclizing); L-Lactate Dehydr

2006
Hypoxia-mediated induction of heme oxygenase type I and carbon monoxide release from astrocytes protects nearby cerebral neurons from hypoxia-mediated apoptosis.
    Antioxidants & redox signaling, 2007, Volume: 9, Issue:5

    Topics: Animals; Apoptosis; Astrocytes; Brain; Brain Ischemia; Carbon Monoxide; Cell Hypoxia; Cell Survival;

2007
CO reveals dual mechanisms of O2 chemoreception in the cat carotid body.
    Respiration physiology, 1993, Volume: 94, Issue:2

    Topics: Animals; Brain Ischemia; Carbon Monoxide; Carotid Body; Cats; Chemoreceptor Cells; Electrophysiology

1993
Failure of iron chelators to protect against cerebral infarction in hypoxia-ischemia.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1993, Volume: 20, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Carbon Monoxide; Cerebral Infarction; Deferoxamine; Hypoxia, Brain;

1993
[Effects of hyperventilation-induced brain ischemia on central nervous system mediator substances in pigs].
    Duodecim; laaketieteellinen aikakauskirja, 1994, Volume: 110, Issue:23-24

    Topics: Anesthesia, General; Animals; Animals, Newborn; Brain Ischemia; Carbon Monoxide; Cerebrovascular Cir

1994
Cerebral hematocrit decreases with hemodynamic compromise in carotid artery occlusion: a PET study.
    Stroke, 1998, Volume: 29, Issue:1

    Topics: Aged; Brain; Brain Ischemia; Carbon Monoxide; Carotid Artery Diseases; Carotid Artery, Internal; Cer

1998
Loss of cerebral regulation during cardiac output variations in focal cerebral ischemia.
    Journal of neurosurgery, 1992, Volume: 77, Issue:2

    Topics: Animals; Blood Viscosity; Blood Volume; Brain Ischemia; Carbon Monoxide; Cardiac Output; Cerebrovasc

1992
[Biochemical and histopathological studies on a mouse brain ischemic model induced by bilateral carotid artery occlusion: comparison with the carbon monoxide inhalation method and other ischemic or anoxic models].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 98, Issue:1

    Topics: Acetylcholine; Adenosine Triphosphate; Administration, Inhalation; Animals; Brain; Brain Ischemia; C

1991
Carbon monoxide (CO)-induced hypoxia in mice: evaluation as an experimental model of cerebral ischemia for drug screening.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:2

    Topics: Animals; Brain Ischemia; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Drug Evaluation

1989