Page last updated: 2024-10-16

carbon monoxide and Breast Cancer

carbon monoxide has been researched along with Breast Cancer in 19 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Research Excerpts

ExcerptRelevanceReference
"Paclitaxel (PTX) is a first-line treatment in breast cancer, though resistance develops quickly and frequently."8.02Carbon Monoxide Inhibits Cytochrome P450 Enzymes CYP3A4/2C8 in Human Breast Cancer Cells, Increasing Sensitivity to Paclitaxel. ( Faull, KF; Janzen, C; Kawahara, B; Mascharak, PK, 2021)
"Lentiviral silencing of CBS in human breast cancer cells attenuated GSH/GSSG, total GSH, nuclear factor erythroid 2-related factor 2 (Nrf2), and processes downstream of Nrf2 that promote GSH synthesis and regeneration of GSH from GSSG."5.46Attenuation of Antioxidant Capacity in Human Breast Cancer Cells by Carbon Monoxide through Inhibition of Cystathionine β-Synthase Activity: Implications in Chemotherapeutic Drug Sensitivity. ( Carrington, S; Faull, KF; Hu-Moore, K; Kawahara, B; Mascharak, PK; Moller, T; Sen, S, 2017)
"Andrographolide (AP) is a diterpene lactone in the leaves and stem of Andrographis paniculata (Burm."5.39Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells. ( Chao, CY; Chen, HW; Hsu, YT; Li, CC; Lii, CK; Liu, KL; Lu, CY, 2013)
"Paclitaxel (PTX) is a first-line treatment in breast cancer, though resistance develops quickly and frequently."4.02Carbon Monoxide Inhibits Cytochrome P450 Enzymes CYP3A4/2C8 in Human Breast Cancer Cells, Increasing Sensitivity to Paclitaxel. ( Faull, KF; Janzen, C; Kawahara, B; Mascharak, PK, 2021)
" Women with breast cancer had lower lung diffusing capacity for carbon monoxide (DLCO), respiratory and limb muscle strength, and ventilatory thresholds during exercise compared with controls (all P < 0."3.83Respiratory Factors Contributing to Exercise Intolerance in Breast Cancer Survivors: A Case-Control Study. ( Dudgeon, DJ; Elbehairy, AF; Langer, D; Neder, JA; O'Donnell, DE; Webb, KA, 2016)
"Lentiviral silencing of CBS in human breast cancer cells attenuated GSH/GSSG, total GSH, nuclear factor erythroid 2-related factor 2 (Nrf2), and processes downstream of Nrf2 that promote GSH synthesis and regeneration of GSH from GSSG."1.46Attenuation of Antioxidant Capacity in Human Breast Cancer Cells by Carbon Monoxide through Inhibition of Cystathionine β-Synthase Activity: Implications in Chemotherapeutic Drug Sensitivity. ( Carrington, S; Faull, KF; Hu-Moore, K; Kawahara, B; Mascharak, PK; Moller, T; Sen, S, 2017)
"Andrographolide (AP) is a diterpene lactone in the leaves and stem of Andrographis paniculata (Burm."1.39Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells. ( Chao, CY; Chen, HW; Hsu, YT; Li, CC; Lii, CK; Liu, KL; Lu, CY, 2013)
"Of interest, patients with breast cancer have been noted to have an increase in endogenous carbon monoxide production via upregulation of heme oxygenase-1 activity."1.39Plasmatic hypercoagulation in patients with breast cancer: role of heme oxygenase-1. ( Alger, PW; Ley, ML; Matika, RW; Nielsen, VG; Steinbrenner, EB; Waer, AL, 2013)
"We selected a group of breast cancer patients in high-dose chemotherapy (HDCT) protocols who were at risk for pulmonary injury."1.33Intrabreath analysis of carbon monoxide uptake during exercise in patients at risk for lung injury. ( Folz, RJ; Huang, YC; Macintyre, NR; O'brien, SR; Vredenburgh, J, 2006)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's0 (0.00)18.2507
2000's4 (21.05)29.6817
2010's9 (47.37)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Guo, W1
Huang, S1
An, J1
Zhang, J2
Dong, F1
Dang, J1
Guan, Q1
Zhou, LL1
Li, YA1
Dong, YB1
Kawahara, B2
Faull, KF2
Janzen, C1
Mascharak, PK3
Moller, T1
Hu-Moore, K1
Carrington, S1
Sen, S1
Chao, CY1
Lii, CK1
Hsu, YT1
Lu, CY1
Liu, KL1
Li, CC1
Chen, HW1
Nielsen, VG1
Ley, ML1
Waer, AL1
Alger, PW1
Matika, RW1
Steinbrenner, EB1
Lee, WY1
Chen, YC2
Shih, CM1
Lin, CM1
Cheng, CH1
Chen, KC1
Lin, CW2
O'Donnell, DE1
Webb, KA1
Langer, D1
Elbehairy, AF1
Neder, JA1
Dudgeon, DJ1
Carrington, SJ1
Chakraborty, I1
Bernard, JM1
Chen, WC1
Kim, J1
Kim, E1
Silverman, P1
Overmoyer, B1
Cooper, BW1
Anthony, S1
Shenk, R1
Leeming, R1
Hanks, SH1
Lyons, JA1
Erven, K1
Weltens, C1
Nackaerts, K1
Fieuws, S1
Decramer, M1
Lievens, Y1
Huang, YC1
O'brien, SR1
Vredenburgh, J1
Folz, RJ1
Macintyre, NR1
Jaén, J1
Vázquez, G1
Alonso, E1
León, A1
Guerrero, R1
Almansa, JF1
Shen, SC1
Hou, WC1
Yang, LY1
Fan, M1
Marks, LB1
Lind, P1
Hollis, D1
Woel, RT1
Bentel, GG1
Anscher, MS1
Shafman, TD1
Coleman, RE1
Jaszczak, RJ1
Munley, MT1
Cavallin-Ståhl, E1
Mercke, C1
Lundh, B1
Weisberg, E1
Senler, TI1
Dean, WL1
Murray, LF1
Wittliff, JL1
Wilson, LD1
Oldham, SB1
Harding, BW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intensity Modulated Radiation Therapy for Breast Cancer: A Phase I Feasibility Study[NCT00594477]Phase 1100 participants (Actual)Interventional2008-01-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for carbon monoxide and Breast Cancer

ArticleYear
Smoking and reproductive health.
    Clinical reproduction and fertility, 1985, Volume: 3, Issue:3

    Topics: Adult; Age Factors; Animals; Breast Feeding; Breast Neoplasms; Carbon Monoxide; Child; Child, Presch

1985

Trials

2 trials available for carbon monoxide and Breast Cancer

ArticleYear
A phase II study of radiotherapy and concurrent paclitaxel chemotherapy in breast-conserving treatment for node-positive breast cancer.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carbon Monoxi

2012
Relating radiation-induced regional lung injury to changes in pulmonary function tests.
    International journal of radiation oncology, biology, physics, 2001, Oct-01, Volume: 51, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Carbon Monoxide; Dose-Response Relationship, Radia

2001

Other Studies

16 other studies available for carbon monoxide and Breast Cancer

ArticleYear
Ultrasound-Mediated Antitumor Therapy via Targeted Acoustic Release Carrier of Carbon Monoxide (TARC-CO).
    ACS applied materials & interfaces, 2022, Nov-16, Volume: 14, Issue:45

    Topics: Breast Neoplasms; Carbon Monoxide; Excipients; Female; Humans; Microbubbles; Ultrasonic Therapy; Ult

2022
A nanoscale metal-organic framework for combined photodynamic and starvation therapy in treating breast tumors.
    Chemical communications (Cambridge, England), 2019, Dec-10, Volume: 55, Issue:99

    Topics: Boron Compounds; Breast Neoplasms; Carbon Monoxide; Female; Humans; Manganese; Metal-Organic Framewo

2019
Carbon Monoxide Inhibits Cytochrome P450 Enzymes CYP3A4/2C8 in Human Breast Cancer Cells, Increasing Sensitivity to Paclitaxel.
    Journal of medicinal chemistry, 2021, 06-24, Volume: 64, Issue:12

    Topics: Antineoplastic Agents; Breast Neoplasms; Carbon Monoxide; Cell Line, Tumor; Cell Survival; Chloramph

2021
Attenuation of Antioxidant Capacity in Human Breast Cancer Cells by Carbon Monoxide through Inhibition of Cystathionine β-Synthase Activity: Implications in Chemotherapeutic Drug Sensitivity.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Carbon Monoxide;

2017
Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells.
    Carcinogenesis, 2013, Volume: 34, Issue:8

    Topics: Bilirubin; Breast Neoplasms; Carbon Monoxide; Cell Line, Tumor; Cell Movement; Diterpenes; Enzyme In

2013
Plasmatic hypercoagulation in patients with breast cancer: role of heme oxygenase-1.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2013, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Blood Coagulation Tests; Breast N

2013
The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide.
    Toxicology and applied pharmacology, 2014, Jan-01, Volume: 274, Issue:1

    Topics: Benzoquinones; Breast Neoplasms; Carbon Monoxide; Cell Line, Tumor; Cell Proliferation; Curcumin; En

2014
Respiratory Factors Contributing to Exercise Intolerance in Breast Cancer Survivors: A Case-Control Study.
    Journal of pain and symptom management, 2016, Volume: 52, Issue:1

    Topics: Breast Neoplasms; Cancer Survivors; Carbon Monoxide; Case-Control Studies; Dyspnea; Exercise Test; E

2016
A Theranostic Two-Tone Luminescent PhotoCORM Derived from Re(I) and (2-Pyridyl)-benzothiazole: Trackable CO Delivery to Malignant Cells.
    Inorganic chemistry, 2016, Aug-15, Volume: 55, Issue:16

    Topics: Benzothiazoles; Breast Neoplasms; Carbon Monoxide; Cell Line, Tumor; Crystallography, X-Ray; Drug Ca

2016
Changes in pulmonary function up to 10 years after locoregional breast irradiation.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemothe

2012
Intrabreath analysis of carbon monoxide uptake during exercise in patients at risk for lung injury.
    Respiratory medicine, 2006, Volume: 100, Issue:7

    Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Breath Tests; Capillaries; Carbon Monoxide; Exercise

2006
Changes in pulmonary function after incidental lung irradiation for breast cancer: A prospective study.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Carbon Monoxide; Dose-Response Relationship, Radiation; Female; Force

2006
Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:5

    Topics: Breast Neoplasms; Carbon Monoxide; Cell Line, Tumor; Cell Movement; Down-Regulation; Female; Heme Ox

2008
Carbon monoxide production in patients with breast carcinoma.
    British journal of haematology, 1976, Volume: 32, Issue:2

    Topics: Adult; Aged; Anemia; Breast Neoplasms; Carbon Monoxide; Erythrocyte Aging; Erythropoiesis; Female; H

1976
Quantification of cytochrome P-450-dependent cyclohexane hydroxylase activity in normal and neoplastic reproductive tissues.
    The Biochemical journal, 1985, Apr-15, Volume: 227, Issue:2

    Topics: Animals; Breast Neoplasms; Carbon Monoxide; Cytochrome P-450 Enzyme System; Female; Humans; Hydroxyl

1985
Cytochrome P450 and steroid 11beta-hydroxylation in mitochondria from human adrenal cortex.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:8

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Antimycin A; Breast Neoplasms; Carbon Monoxide; Cushing S

1968