carbon monoxide has been researched along with Blood Clot in 21 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
| Excerpt | Relevance | Reference |
|---|---|---|
| "CORM-3 and CORM-A1 inhibited thrombosis in vivo, however CORM-A1, which slowly releases carbon monoxide, and displayed a relatively weak hypotensive effect had a more pronounced antithrombotic effect associated with a stronger inhibition of platelet aggregation associated with a decrease in active plasminogen activator inhibitor-1 concentration." | 3.78 | Antithrombotic properties of water-soluble carbon monoxide-releasing molecules. ( Brzoska, T; Buczko, W; Chlopicki, S; Fedorowicz, A; Grochal, E; Kramkowski, K; Leszczynska, A; Mann, B; Mogielnicki, A; Motterlini, R; Urano, T, 2012) |
| " Future investigation must determine if carbon monoxide releasing molecules could be used therapeutically to control bleeding in warfarin-treated patients." | 3.76 | Carbon monoxide releasing molecule-2 enhances coagulation and diminishes fibrinolytic vulnerability in subjects exposed to warfarin. ( George, JF; Khan, ES; Kirklin, JK; Nielsen, VG, 2010) |
| "Finally, the arrhythmia-inducing potential may result from catecholamine release following nicotine exposure, with a questionable contribution from carbon monoxide." | 2.41 | Particulate and vapor phase constituents of cigarette mainstream smoke and risk of myocardial infarction. ( Fischer, TH; Smith, CJ, 2001) |
| "Arterial thrombosis is a critical event in the pathogenesis of lesion development." | 1.33 | Carbon monoxide-induced early thrombolysis contributes to heme oxygenase-1-mediated inhibition of neointimal growth after vascular injury in hypercholesterolemic mice. ( Chau, LY; Chen, YH; Chiang, MT; Tsai, HL, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 12 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nielsen, VG | 9 |
| Hafner, DT | 2 |
| Steinbrenner, EB | 2 |
| Pearson, EC | 1 |
| Smith, MC | 1 |
| Olas, B | 1 |
| Carlsten, C | 1 |
| Kaufman, JD | 1 |
| Trenga, CA | 1 |
| Allen, J | 1 |
| Peretz, A | 1 |
| Sullivan, JH | 1 |
| Chen, B | 1 |
| Guo, L | 1 |
| Fan, C | 1 |
| Bolisetty, S | 1 |
| Joseph, R | 1 |
| Wright, MM | 1 |
| Agarwal, A | 1 |
| George, JF | 2 |
| Khan, ES | 1 |
| Kirklin, JK | 1 |
| Malayaman, SN | 3 |
| Cohen, JB | 2 |
| Machovec, KA | 1 |
| Bernhardt, BE | 1 |
| Arkebauer, MR | 2 |
| Soni, H | 1 |
| Jain, M | 1 |
| Mehta, AA | 1 |
| Nowak, M | 1 |
| Vosseller, K | 2 |
| Kanaparthy, SS | 1 |
| Kramkowski, K | 1 |
| Leszczynska, A | 1 |
| Mogielnicki, A | 1 |
| Chlopicki, S | 1 |
| Fedorowicz, A | 1 |
| Grochal, E | 1 |
| Mann, B | 1 |
| Brzoska, T | 1 |
| Urano, T | 1 |
| Motterlini, R | 1 |
| Buczko, W | 1 |
| Olver, CS | 1 |
| Chen, YH | 1 |
| Tsai, HL | 1 |
| Chiang, MT | 1 |
| Chau, LY | 1 |
| Scott, JR | 1 |
| Chin, BY | 1 |
| Bilban, MH | 1 |
| Otterbein, LE | 1 |
| True, AL | 1 |
| Olive, M | 1 |
| Boehm, M | 1 |
| San, H | 1 |
| Westrick, RJ | 1 |
| Raghavachari, N | 1 |
| Xu, X | 1 |
| Lynn, EG | 1 |
| Sack, MN | 1 |
| Munson, PJ | 1 |
| Gladwin, MT | 1 |
| Nabel, EG | 1 |
| Adnot, S | 1 |
| Sato, K | 1 |
| Balla, J | 1 |
| Otterbein, L | 1 |
| Smith, RN | 1 |
| Brouard, S | 1 |
| Lin, Y | 1 |
| Csizmadia, E | 1 |
| Sevigny, J | 1 |
| Robson, SC | 1 |
| Vercellotti, G | 1 |
| Choi, AM | 1 |
| Bach, FH | 1 |
| Soares, MP | 1 |
| Smith, CJ | 1 |
| Fischer, TH | 1 |
| Ball, K | 1 |
| Turner, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| HEMolysis in a Percutaneous Axial Flow Left Ventricular Assist Device, Effects of Pentoxifylline in a Randomized Controlled Trial[NCT04391231] | Phase 4 | 50 participants (Anticipated) | Interventional | 2021-09-15 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for carbon monoxide and Blood Clot
| Article | Year |
|---|---|
Increased carbon monoxide production by hemeoxygenase-1 caused by device-mediated hemolysis: thrombotic phantom menace?
Topics: Animals; Blood Coagulation; Carbon Monoxide; Heart-Assist Devices; Heme Oxygenase-1; Hemolysis; Huma | 2013 |
Gasomediators (·NO, CO, and H₂S) and their role in hemostasis and thrombosis.
Topics: Blood Platelets; Carbon Monoxide; Endothelial Cells; Fibrinogen; Hemostasis; Humans; Hydrogen Sulfid | 2015 |
[Tobacco: an atherogenic, thrombogenic or spasmogenic factor?].
Topics: Arteriosclerosis; Carbon Monoxide; Cause of Death; Humans; Myocardial Infarction; Nicotiana; Oxidati | 1998 |
Particulate and vapor phase constituents of cigarette mainstream smoke and risk of myocardial infarction.
Topics: Animals; Arrhythmias, Cardiac; Arteriosclerosis; Carbon Monoxide; Humans; Hypoxia; Myocardial Infarc | 2001 |
1 trial available for carbon monoxide and Blood Clot
| Article | Year |
|---|---|
Thrombotic markers in metabolic syndrome subjects exposed to diesel exhaust.
Topics: Adult; Air Pollutants; Biomarkers; Carbon Monoxide; Cross-Over Studies; Female; Humans; Male; Metabo | 2008 |
16 other studies available for carbon monoxide and Blood Clot
| Article | Year |
|---|---|
Tobacco smoke-induced hypercoagulation in human plasma: role of carbon monoxide.
Topics: Adolescent; Adult; Blood Coagulation Tests; Carbon Monoxide; Carboxyhemoglobin; Case-Control Studies | 2013 |
Can divergent plasmin-antiplasmin-carbon monoxide interactions in young, healthy tobacco smokers explain the 'smoker's paradox'?
Topics: Adolescent; Adult; Antifibrinolytic Agents; Carbon Monoxide; Carboxyhemoglobin; Case-Control Studies | 2013 |
Carbon monoxide rescues heme oxygenase-1-deficient mice from arterial thrombosis in allogeneic aortic transplantation.
Topics: Animals; Aorta; Blotting, Western; Carbon Monoxide; Graft Survival; Heme Oxygenase-1; Mice; Microsco | 2009 |
Carbon monoxide releasing molecule-2 enhances coagulation and diminishes fibrinolytic vulnerability in subjects exposed to warfarin.
Topics: Blood Coagulation; Carbon Monoxide; Fibrinolysis; Hemorrhage; Humans; International Normalized Ratio | 2010 |
The antifibrinolytic effects of carbon monoxide-releasing molecule-2 are fibrin and alpha2-antiplasmin dependent.
Topics: alpha-2-Antiplasmin; Antifibrinolytic Agents; Blood Coagulation; Carbon Monoxide; Fibrin; Fibrinolys | 2010 |
Carbon monoxide releasing molecule-2 enhances α2-antiplasmin activity.
Topics: alpha-2-Antiplasmin; Antifibrinolytic Agents; Blood Coagulation Tests; Carbon Monoxide; Fibrinogen; | 2011 |
Investigation into the mechanism(s) of antithrombotic effects of carbon monoxide releasing molecule-3 (CORM-3).
Topics: Animals; Antithrombins; Blood Platelets; Carbon Monoxide; Disease Models, Animal; Humans; Male; Orga | 2011 |
Fibrinogen is a heme-associated, carbon monoxide sensing molecule: a preliminary report.
Topics: Blood Coagulation; Carbon Monoxide; Fibrinogen; Heme; Humans; Kinetics; Organometallic Compounds; Pl | 2011 |
Carbon monoxide and nitric oxide modulate α₂-antiplasmin and plasmin activity: role of heme.
Topics: alpha-2-Antiplasmin; Antifibrinolytic Agents; Carbon Monoxide; Chromatography, Liquid; Dose-Response | 2011 |
Antithrombotic properties of water-soluble carbon monoxide-releasing molecules.
Topics: Animals; Arterial Occlusive Diseases; Blood Coagulation; Blood Gas Analysis; Blood Platelets; Blood | 2012 |
Thrombelastographic characterization of coagulation/fibrinolysis in horses: role of carboxyheme and metheme states.
Topics: Animals; Blood Coagulation; Blood Coagulation Tests; Carbon Monoxide; Carboxyhemoglobin; Enteritis; | 2013 |
Carbon monoxide-induced early thrombolysis contributes to heme oxygenase-1-mediated inhibition of neointimal growth after vascular injury in hypercholesterolemic mice.
Topics: Animals; Apolipoproteins E; Carbon Monoxide; Carotid Artery, Common; Fibrin; Fibrinogen; Heme Oxygen | 2006 |
Restoring HOmeostasis: is heme oxygenase-1 ready for the clinic?
Topics: Atherosclerosis; Bilirubin; Biliverdine; Carbon Monoxide; Cytoprotection; Heme Oxygenase-1; Homeosta | 2007 |
Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.
Topics: Administration, Inhalation; Animals; Apoptosis; Biliverdine; Carbon Monoxide; Endothelium, Vascular; | 2007 |
Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants.
Topics: Acute Disease; Animals; Apoptosis; Carbon Monoxide; Cell Line; Cell Movement; Endothelium, Vascular; | 2001 |
Smoking and the heart. The basis for action.
Topics: Adult; Age Factors; Angina Pectoris; Arteriosclerosis; Carbon Monoxide; Cholesterol; Coronary Diseas | 1974 |