Page last updated: 2024-10-16

carbon monoxide and Bilirubinemia

carbon monoxide has been researched along with Bilirubinemia in 27 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Research Excerpts

ExcerptRelevanceReference
" The main aims were to inspect the erythrocyte (RBC) survival in GS by using Levitt's carbon monoxide (CO) breath test and to assess its contribution to unconjugated hyperbilirubinemia."9.34Carbon monoxide breath test assessment of mild hemolysis in Gilbert's syndrome. ( Kang, LL; Ma, YJ; Zhang, HD, 2020)
"The predominant cause of elevated total/plasma bilirubin (TB) levels is from an increase in bilirubin production primarily because of ongoing hemolysis."9.12Neonatal hyperbilirubinemia management: Clinical assessment of bilirubin production. ( Bao, Y; Bhutani, VK; Chen, L; Du, L; Ma, X; Shen, X, 2021)
" Routine management included measurement of the end tidal carbon monoxide level corrected for ambient carbon monoxide level (ETCOc) within 4 hours after delivery (assessment of hemolysis), > or =1 predischarge bilirubin determination, and additional bilirubin testing as clinically indicated."7.72Hyperbilirubinemia among African American, glucose-6-phosphate dehydrogenase-deficient neonates. ( Hammerman, C; Herschel, M; Hoyer, JD; Kaplan, M; Stevenson, DK, 2004)
"The purpose of this study was to determine whether end-tidal carbon monoxide (CO) corrected for ambient CO (ETCOc), as a single measurement or in combination with serum total bilirubin (STB) measurements, can predict the development of hyperbilirubinemia during the first 7 days of life."7.71Prediction of hyperbilirubinemia in near-term and term infants. ( Bhutani, VK; Fanaroff, AA; Gale, R; Hammerman, C; Johnson, LH; Kaplan, M; MacMahon, JR; Maisels, MJ; Nakamura, H; Oh, W; Seidman, DS; Stevenson, DK; Vreman, HJ; Wong, RJ; Yeung, CY; Young, BW, 2001)
"Pulmonary carbon monoxide (CO) excretion rates (VeCO) were 50% greater, on average, in Bolivian squirrel monkeys (BoSMs) which exhibit a unique fasting hyperbilirubinemia (FH), than in fasted control Brazilian squirrel monkeys (BrSMs)."7.68Increased carbon monoxide excretion in Bolivian squirrel monkeys with fasting hyperbilirubinemia. ( Cornelius, CE; Rodgers, PA; Tarkington, BK; Vreman, HJ, 1990)
"Hyperbilirubinemia is a condition of major importance and a source of concern to all involved in the management of the newborn."6.43Understanding severe hyperbilirubinemia and preventing kernicterus: adjuncts in the interpretation of neonatal serum bilirubin. ( Hammerman, C; Kaplan, M, 2005)
"When hemolysis is identified, parents are likely to comply with instructions to bring the infant for a TB checkup <24 h after discharge home."5.43Measuring End-Tidal Carbon Monoxide of Jaundiced Neonates in the Birth Hospital to Identify Those with Hemolysis. ( Baer, VL; Christensen, RD; Denson, LE; Gerday, E; Lambert, DK; Malleske, DT; Prchal, JT; Shepherd, JG; Weaver Lewis, KA, 2016)
" Before the recent development of practical and inexpensive testing for hemolysis by quantifying carbon monoxide in end-tidal breath, some hemolytic disorders in perinatal patients were not detected until severely problematic hyperbilirubinemia and/or anemia occurred."5.41Perinatal Hemolytic Disorders and Identification Using End Tidal Breath Carbon Monoxide. ( Bahr, TM; Christensen, RD; Pakdeeto, S; Supapannachart, S; Zhang, H, 2023)
" The main aims were to inspect the erythrocyte (RBC) survival in GS by using Levitt's carbon monoxide (CO) breath test and to assess its contribution to unconjugated hyperbilirubinemia."5.34Carbon monoxide breath test assessment of mild hemolysis in Gilbert's syndrome. ( Kang, LL; Ma, YJ; Zhang, HD, 2020)
"The predominant cause of elevated total/plasma bilirubin (TB) levels is from an increase in bilirubin production primarily because of ongoing hemolysis."5.12Neonatal hyperbilirubinemia management: Clinical assessment of bilirubin production. ( Bao, Y; Bhutani, VK; Chen, L; Du, L; Ma, X; Shen, X, 2021)
"To establish a reference nomogram for end-tidal CO corrected for ambient CO (ETCOc) levels in term and late-preterm Chinese newborns and then assess its efficacy to identify hemolytic hyperbilirubinemia."4.12An End-Tidal Carbon Monoxide Nomogram for Term and Late-Preterm Chinese Newborns. ( Bao, Y; Du, L; He, Y; Ma, L; Sun, L; Wu, J; Xu, C; Zhang, H; Zhu, J, 2022)
" The use of tin mesoporphyrin (SnMP) has been proposed for interdicting the development of severe hyperbilirubinemia in a variety of conditions."3.73The effectiveness of oral tin mesoporphyrin prophylaxis in reducing bilirubin production after an oral heme load in a transgenic mouse model. ( Contag, CH; DeSandre, GH; Morioka, I; Stevenson, DK; Wong, RJ, 2006)
" Routine management included measurement of the end tidal carbon monoxide level corrected for ambient carbon monoxide level (ETCOc) within 4 hours after delivery (assessment of hemolysis), > or =1 predischarge bilirubin determination, and additional bilirubin testing as clinically indicated."3.72Hyperbilirubinemia among African American, glucose-6-phosphate dehydrogenase-deficient neonates. ( Hammerman, C; Herschel, M; Hoyer, JD; Kaplan, M; Stevenson, DK, 2004)
"The purpose of this study was to determine whether end-tidal carbon monoxide (CO) corrected for ambient CO (ETCOc), as a single measurement or in combination with serum total bilirubin (STB) measurements, can predict the development of hyperbilirubinemia during the first 7 days of life."3.71Prediction of hyperbilirubinemia in near-term and term infants. ( Bhutani, VK; Fanaroff, AA; Gale, R; Hammerman, C; Johnson, LH; Kaplan, M; MacMahon, JR; Maisels, MJ; Nakamura, H; Oh, W; Seidman, DS; Stevenson, DK; Vreman, HJ; Wong, RJ; Yeung, CY; Young, BW, 2001)
"Pulmonary carbon monoxide (CO) excretion rates (VeCO) were 50% greater, on average, in Bolivian squirrel monkeys (BoSMs) which exhibit a unique fasting hyperbilirubinemia (FH), than in fasted control Brazilian squirrel monkeys (BrSMs)."3.68Increased carbon monoxide excretion in Bolivian squirrel monkeys with fasting hyperbilirubinemia. ( Cornelius, CE; Rodgers, PA; Tarkington, BK; Vreman, HJ, 1990)
"The role of increased heme catabolism in neonatal hyperbilirubinemia was investigated in rhesus (Macaca mulatta) neonates through the measurement of carbon monoxide excretion rates (VECO), blood carboxyhemoglobin content (HbCO), and plasma bilirubin concentrations."3.67Carbon monoxide excretion as an index of bilirubin production in rhesus monkeys. ( Gale, R; Rodgers, PA; Stevenson, DK; Vreman, HJ, 1989)
"Hyperbilirubinemia is a condition of major importance and a source of concern to all involved in the management of the newborn."2.43Understanding severe hyperbilirubinemia and preventing kernicterus: adjuncts in the interpretation of neonatal serum bilirubin. ( Hammerman, C; Kaplan, M, 2005)
"When hemolysis is identified, parents are likely to comply with instructions to bring the infant for a TB checkup <24 h after discharge home."1.43Measuring End-Tidal Carbon Monoxide of Jaundiced Neonates in the Birth Hospital to Identify Those with Hemolysis. ( Baer, VL; Christensen, RD; Denson, LE; Gerday, E; Lambert, DK; Malleske, DT; Prchal, JT; Shepherd, JG; Weaver Lewis, KA, 2016)
"To facilitate comparison, hyperbilirubinemia was induced through a 36-hr period of subtotal caloric restriction before the study."1.26Glucose administration and heme catabolism after caloric restriction. ( Lundh, B; Ugander, L, 1976)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199010 (37.04)18.7374
1990's5 (18.52)18.2507
2000's5 (18.52)29.6817
2010's2 (7.41)24.3611
2020's5 (18.52)2.80

Authors

AuthorsStudies
Bao, Y2
Zhu, J1
Ma, L1
Zhang, H2
Sun, L1
Xu, C1
Wu, J1
He, Y1
Du, L2
Christensen, RD2
Bahr, TM1
Pakdeeto, S1
Supapannachart, S1
Kang, LL1
Ma, YJ1
Zhang, HD1
Elsaie, AL1
Taleb, M1
Nicosia, A1
Zangaladze, A1
Pease, ME1
Newton, K1
Schutzman, DL1
Ma, X1
Shen, X1
Chen, L1
Bhutani, VK3
Wong, RJ3
Vreman, HJ6
Stevenson, DK8
Malleske, DT1
Lambert, DK1
Baer, VL1
Prchal, JT1
Denson, LE1
Gerday, E1
Weaver Lewis, KA1
Shepherd, JG1
FLAUTO, U1
BONCOMPAGNI, P1
MARINI, A1
Kaplan, M4
Herschel, M1
Hammerman, C4
Hoyer, JD1
DeSandre, GH1
Morioka, I1
Contag, CH1
Wranne, L1
Marks, GS1
Leiter, C1
Abramov, A1
Labbé, RF1
Schüller Pérez, A1
Fanaroff, AA1
Maisels, MJ2
Young, BW1
MacMahon, JR1
Yeung, CY1
Seidman, DS1
Gale, R2
Oh, W1
Johnson, LH1
Nakamura, H1
Valaes, T1
Bartoletti, AL1
Ostrander, CR1
Johnson, JD1
Lundh, B1
Ugander, L1
Rodgers, PA2
Cornelius, CE1
Tarkington, BK1
Robinson, SH1
Pathak, A1
Nelson, NM1
Kandall, SR1
Landaw, SA1
Thaler, MM1
Fällström, SP1
Bjure, J1
Bloomer, JR1
Barrett, PV1
Rodkey, FL1
Berlin, NI1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Value of ETCOc in the Diagnosis and Treatment of ABO Hemolytic Disease of the Newborn[NCT05842109]112 participants (Anticipated)Observational2023-05-01Not yet recruiting
End Tidal Carbon Monoxide (ETCO) : A Tool to Aid Identification of Neonatal Hemolysis[NCT05475223]350 participants (Anticipated)Interventional2022-07-29Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for carbon monoxide and Bilirubinemia

ArticleYear
Perinatal Hemolytic Disorders and Identification Using End Tidal Breath Carbon Monoxide.
    Current pediatric reviews, 2023, Volume: 19, Issue:4

    Topics: Carbon Monoxide; Cell Death; Female; Hemolysis; Humans; Hyperbilirubinemia; Infant, Newborn; Infant,

2023
Neonatal hyperbilirubinemia management: Clinical assessment of bilirubin production.
    Seminars in perinatology, 2021, Volume: 45, Issue:1

    Topics: Bilirubin; Carbon Monoxide; Hemolysis; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Neonatal; Inf

2021
Understanding severe hyperbilirubinemia and preventing kernicterus: adjuncts in the interpretation of neonatal serum bilirubin.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 356, Issue:1-2

    Topics: Bilirubin; Blood Group Incompatibility; Carbon Monoxide; Hemolysis; Humans; Hyperbilirubinemia; Infa

2005
Heme oxygenase: the physiological role of one of its metabolites, carbon monoxide and interactions with zinc protoporphyrin, cobalt protoporphyrin and other metalloporphyrins.
    Cellular and molecular biology (Noisy-le-Grand, France), 1994, Volume: 40, Issue:7

    Topics: Animals; Carbon Monoxide; Heme Oxygenase (Decyclizing); Humans; Hyperbilirubinemia; Long-Term Potent

1994
Zinc protoporphyrin: A metabolite with a mission.
    Clinical chemistry, 1999, Volume: 45, Issue:12

    Topics: Anemia, Iron-Deficiency; Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Erythrocytes; Heme;

1999
[The heme oxygenase system and its physiopathology].
    Anales de la Real Academia Nacional de Medicina, 1999, Volume: 116, Issue:3

    Topics: Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Hyperbilirubinemia; Iron;

1999
Formation of bilirubin from erythroid and nonerythroid sources.
    Seminars in hematology, 1972, Volume: 9, Issue:1

    Topics: Anemia, Aplastic; Animals; Bile Pigments; Bilirubin; Blood Transfusion; Carbon Isotopes; Carbon Mono

1972

Trials

1 trial available for carbon monoxide and Bilirubinemia

ArticleYear
Carbon monoxide breath test assessment of mild hemolysis in Gilbert's syndrome.
    Medicine, 2020, Volume: 99, Issue:7

    Topics: Adult; Breath Tests; Carbon Monoxide; Erythrocytes; Female; Gilbert Disease; Hemolysis; Humans; Hype

2020

Other Studies

19 other studies available for carbon monoxide and Bilirubinemia

ArticleYear
An End-Tidal Carbon Monoxide Nomogram for Term and Late-Preterm Chinese Newborns.
    The Journal of pediatrics, 2022, Volume: 250

    Topics: Bilirubin; Carbon Monoxide; China; Hemolysis; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Neonat

2022
Comparison of end-tidal carbon monoxide measurements with direct antiglobulin tests in the management of neonatal hyperbilirubinemia.
    Journal of perinatology : official journal of the California Perinatal Association, 2020, Volume: 40, Issue:10

    Topics: Bilirubin; Carbon Monoxide; Child; Coombs Test; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Neon

2020
Bilirubin production and hour-specific bilirubin levels.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:9

    Topics: Bilirubin; Carbon Monoxide; Female; Gestational Age; Humans; Hyperbilirubinemia; Infant, Newborn; In

2015
Measuring End-Tidal Carbon Monoxide of Jaundiced Neonates in the Birth Hospital to Identify Those with Hemolysis.
    Neonatology, 2016, Volume: 109, Issue:1

    Topics: Bilirubin; Birthing Centers; Breath Tests; Carbon Monoxide; Female; Hematologic Tests; Heme; Hemolys

2016
[BEHAVIOR OF CARBOXYHEMOGLOBIN IN HEMOLYTIC DISEASE OF THE NEWBORN].
    Minerva pediatrica, 1964, Sep-29, Volume: 16

    Topics: ABO Blood-Group System; Carbon Monoxide; Carboxyhemoglobin; Erythroblastosis, Fetal; Fetus; Hemoglob

1964
Hyperbilirubinemia among African American, glucose-6-phosphate dehydrogenase-deficient neonates.
    Pediatrics, 2004, Volume: 114, Issue:2

    Topics: Bilirubin; Black People; Carbon Monoxide; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydroge

2004
The effectiveness of oral tin mesoporphyrin prophylaxis in reducing bilirubin production after an oral heme load in a transgenic mouse model.
    Biology of the neonate, 2006, Volume: 89, Issue:3

    Topics: Animals; Bilirubin; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Hyperbilirubine

2006
Studies on erythro-kinetics in infancy. VII. Quantitative estimation of the haemoglobin catabolism by carbon monoxide technique in young infants.
    Acta paediatrica Scandinavica, 1967, Volume: 56, Issue:4

    Topics: Air; Bilirubin; Blood Group Incompatibility; Carbon Monoxide; Erythrocyte Aging; Erythrocytes; Femal

1967
Contribution of haemolysis to jaundice in Sephardic Jewish glucose-6-phosphate dehydrogenase deficient neonates.
    British journal of haematology, 1996, Volume: 93, Issue:4

    Topics: Carbon Monoxide; Carboxyhemoglobin; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Hy

1996
Prediction of hyperbilirubinemia in near-term and term infants.
    Pediatrics, 2001, Volume: 108, Issue:1

    Topics: Bilirubin; Carbon Monoxide; Female; Gestational Age; Humans; Hyperbilirubinemia; Infant, Newborn; Ma

2001
Problems with prediction of neonatal hyperbilirubinemia.
    Pediatrics, 2001, Volume: 108, Issue:1

    Topics: Bilirubin; Carbon Monoxide; Evidence-Based Medicine; Humans; Hyperbilirubinemia; Infant, Newborn; Mu

2001
Pulmonary excretion of carbon monoxide in the human newborn infant as an index of bilirubin production: III. Measurement of pulmonary excretion of carbon monoxide after the first postnatal week in premature infants.
    Pediatrics, 1979, Volume: 64, Issue:5

    Topics: Bilirubin; Carbon Monoxide; Erythrocyte Aging; Gestational Age; Humans; Hyperbilirubinemia; Infant,

1979
Glucose administration and heme catabolism after caloric restriction.
    Gastroenterology, 1976, Volume: 71, Issue:6

    Topics: Administration, Oral; Adult; Bilirubin; Carbon Monoxide; Diet; Energy Intake; Glucose; Heme; Humans;

1976
Increased carbon monoxide excretion in Bolivian squirrel monkeys with fasting hyperbilirubinemia.
    Journal of medical primatology, 1990, Volume: 19, Issue:5

    Topics: Animals; Bilirubin; Bolivia; Brazil; Carbon Monoxide; Disease Models, Animal; Fasting; Gilbert Disea

1990
Carbon monoxide excretion as an index of bilirubin production in rhesus monkeys.
    Journal of medical primatology, 1989, Volume: 18, Issue:6

    Topics: Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; He

1989
The effect of exchange transfusion on endogenous carbon monoxide production in erythroblastotic infants.
    The Journal of pediatrics, 1972, Volume: 81, Issue:4

    Topics: Bilirubin; Body Weight; Carbon Monoxide; Chromatography, Gas; Erythroblastosis, Fetal; Exchange Tran

1972
Carboxyhemoglobin exchange between donors and recipients of blood transfusions.
    Pediatrics, 1973, Volume: 52, Issue:5

    Topics: Birth Weight; Blood Donors; Blood Gas Analysis; Carbon Monoxide; Carboxyhemoglobin; Chromatography,

1973
Endogenous formation of carbon monoxide in newborn infants. II. Rh haemolytic disease of the newborn.
    Acta paediatrica Scandinavica, 1967, Volume: 56, Issue:4

    Topics: Carbon Monoxide; Erythroblastosis, Fetal; Erythrocytes; Exchange Transfusion, Whole Blood; Female; H

1967
Studies on the mechanism of fasting hyperbilirubinemia.
    Gastroenterology, 1971, Volume: 61, Issue:4

    Topics: Animals; Bilirubin; Body Weight; Carbon Monoxide; Fasting; Humans; Hyperbilirubinemia; Hyperbilirubi

1971