carbon monoxide and Asthma, Bronchial studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Research Excerpts

Excerpt	Relevance	Reference
"The aim of this study was to assess the effect of oral prednisone treatment on FE(NO) and ECO levels in a group of 30 asthmatic children with asthma exacerbation."	9.10	Exhaled carbon monoxide levels after a course of oral prednisone in children with asthma exacerbation. ( Baraldi, E; Landi, L; Scollo, M; Zacchello, F; Zanconato, S; Zaramella, C, 2002)
"This study was performed to investigate the relationship between the hospitalization rate for asthma and the ambient carbon monoxide (CO) by examining regional variation of the hospitalization rates for asthma in Korea and its factors."	7.96	Regional Variation of Hospitalization Rates for Asthma in Korea: Association with Ambient Carbon Monoxide and Health Care Supply. ( Kang, S; Kim, AM; Kim, Y; Park, JH, 2020)
"Interquartile range increases in ultrafine particles and carbon monoxide concentrations in the previous 7 days were associated with increases in the relative odds of a pediatric asthma visit, with the largest increases observed for 4-day mean ultrafine particles (interquartile range=2088p/cm(3); OR=1."	7.80	Increased ultrafine particles and carbon monoxide concentrations are associated with asthma exacerbation among urban children. ( Evans, KA; Fagnano, M; Halterman, JS; Hopke, PK; Rich, DQ, 2014)
"5) and exhaled carbon monoxide (eCO) measured in non-asthmatic children."	7.79	Dose-dependent relationship between prenatal exposure to fine particulates and exhaled carbon monoxide in non-asthmatic children. A population-based birth cohort study. ( Flak, E; Jacek, R; Jędrychowski, WA; Klimaszewska-Rembiasz, M; Maugeri, U; Mróz, E; Sowa, A; Spengler, J, 2013)
"The concentration of exhaled carbon monoxide (eCO) in young children with stable asthma and during acute asthma attack is not known."	7.78	Exhaled carbon monoxide levels in preschool-age children with episodic asthma. ( Arai, H; Asamura, T; Morikawa, T; Ohara, T; Ohara, Y; Ohrui, T; Sasaki, H, 2012)
"A study was conducted to evaluate the role of exhaled carbon monoxide (CO) levels in the management of patients with mild and moderate persistent bronchial asthma."	7.74	Exhaled carbon monoxide levels: as a marker of clinical severity and control of asthma. ( Grover, RS; Kumar, R, 2008)
"Carbon monoxide (CO) can be detected in exhaled air and is increased in adult and childhood persistent asthmatic patients."	7.73	Exhaled carbon monoxide levels in school-age children with episodic asthma. ( He, M; Morikawa, T; Ohara, Y; Ohrui, T; Sasaki, H; Yamaya, M; Yasuda, H, 2006)
"The study objectives were to analyze the changes in exhaled carbon monoxide (COex) induced by histamine provocation challenge in asthmatic patients and to evaluate the relationship between COex and airway sensitivity and reactivity."	7.72	Relationship between exhaled carbon monoxide and airway hyperresponsiveness in asthmatic patients. ( García-Río, F; Pino, JM; Prados, C; Ramirez, M; Villamor, J; Viñas, A, 2004)
"Three hundred thirty-one consecutive outpatients (161 with asthma and 170 with COPD) were examined cross-sectionally by self-reported smoking status, breath CO monitoring, and serum cotinine concentration."	7.72	Optimal cutoff level of breath carbon monoxide for assessing smoking status in patients with asthma and COPD. ( Hajiro, T; Koyama, H; Mishima, M; Nishimura, K; Oga, T; Sato, S; Tsukino, M, 2003)
"Exhaled nitric oxide (eNO) and carbon monoxide (eCO) concentrations are elevated in inflammatory airway diseases like asthma and have been investigated as potential diagnostic markers."	7.72	Exhaled carbon monoxide is not flow dependent in children with cystic fibrosis and asthma. ( Beck-Ripp, J; Griese, M; Latzin, P, 2004)
"Exhaled carbon monoxide is a useful marker of airway inflammation in untreated asthma."	7.71	An assessment of the role of exhaled carbon monoxide in acute asthmatic exacerbations in hospitalised patients. ( Chan, CC; Kong, PM; Lee, P; Wang, YT, 2002)
"Carbon monoxide (CO) can be detected in exhaled air and is increased in asthmatic patients not treated with corticosteroids."	7.71	Relation between exhaled carbon monoxide levels and clinical severity of asthma. ( Hosoda, M; Ishizuka, S; Matsui, T; Monma, M; Sasaki, H; Sekizawa, K; Suzuki, T; Yamaya, M, 2001)
"Increased levels of exhaled carbon monoxide (fractional concentration of CO in expired gas (FE,CO)), measured with an electrochemical sensor, have been reported in patients with inflammatory airway disorders, such as asthma, rhinitis and cystic fibrosis."	7.71	Exhaled carbon monoxide is not elevated in patients with asthma or cystic fibrosis. ( Alving, K; Ihre, E; Johannesson, M; Lundberg, JO; Marteus, H; Nordval, SL; Zetterquist, W, 2002)
"The bronchoalveolar lavage cellular constituents of patients with sulfur mustard gas-induced asthma and chronic bronchitis are similar to those that have been observed previously in patients with asthma and chronic bronchitis from other common causes."	7.70	Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis. ( Emad, A; Rezaian, GR, 1999)
"Exhaled CO and sputum bilirubin levels were measured and HO-1 protein expression in airway macrophages was determined by Western blotting in asthmatic patients as levels of oxidants are raised in asthma and may induce HO-1."	7.70	Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress. ( Barnes, PJ; Donnelly, LE; Horváth, I; Kharitonov, SA; Kiss, A; Paredi, P, 1998)
"Carbon monoxide is known to be present in measurable quantities in the exhaled air of normal subjects and at higher concentrations in asthmatic patients not treated with glucocorticoids."	7.70	Exhaled carbon monoxide levels during treatment of acute asthma. ( Ishizuka, S; Monma, M; Sasaki, H; Sekizawa, K; Yamara, M; Yamaya, M, 1999)
"To investigate the role of carbon monoxide (CO) in the pathogenesis of asthma."	7.70	[Evidence of increased endogenous carbon monoxide production in asthma]. ( Jiang, D; Li, H; Shi, Y, 1999)
"Exhaled carbon monoxide (CO) concentrations were measured on a CO monitor by vital capacity maneuvers in asthmatic patients receiving or not receiving inhaled corticosteroids and in nonsmoking and smoking healthy control subjects."	7.69	Increased carbon monoxide in exhaled air of asthmatic patients. ( Ohrui, T; Okinaga, S; Sasaki, H; Sekizawa, K; Yamaya, M; Zayasu, K, 1997)
"The aim of this study was to test the hypothesis that carbon monoxide diffusing capacity (DCO) is elevated in asthmatic patients with minimal airflow limitation and/or hyperinflation; the latter factors should reduce the possibility of technical errors in the measurement of DCO."	7.67	Carbon monoxide diffusing capacity in asthmatic patients with mild airflow limitation. ( Stewart, RI, 1988)
"Ozone (O₃) was associated with a 13-22% increased risk of stillbirth on days 2, 3, and 5-7 prior to delivery in single pollutant models, and these findings persisted in multi-pollutant models for days 5 (RR = 1."	5.46	Chronic and Acute Ozone Exposure in the Week Prior to Delivery Is Associated with the Risk of Stillbirth. ( Ha, S; Kim, SS; Liu, D; Mendola, P; Pollack, AZ; Seeni, I; Sherman, S; Zhu, Y, 2017)
"Bronchial asthma is characterised by chronic airway inflammation commonly associated with increased oxidative stress."	5.40	Factors influencing the levels of exhaled carbon monoxide in asthmatic children. ( Babusikova, E; Banovcin, P; Dobrota, D; Havlicekova, Z; Jesenak, M, 2014)
"Ozone exposure was significantly associated with the 12-month prevalence of wheeze (odds ratio per 5 ppb, 1."	5.37	Association of ozone exposure with asthma, allergic rhinitis, and allergic sensitization. ( Ha, M; Hong, SJ; Hong, YC; Kang, DM; Kim, BJ; Kim, HB; Kim, HC; Kim, SY; Kwon, HJ; Kwon, JW; Lee, CG; Lee, SY; Leem, JH; Park, KS; Sakong, J; Seo, JH; Yu, J, 2011)
"Carbon monoxide is a product of haem degradation by haem oxygenase (HO), activated by inflammatory cytokines and oxidants."	5.30	Changes in exhaled carbon monoxide and nitric oxide levels following allergen challenge in patients with asthma. ( Allegra, L; Barnes, PJ; Horvath, I; Kharitonov, SA; Leckie, MJ; Paredi, P, 1999)
"We also studied whether upper respiratory tract infections were associated with elevated exhaled CO."	5.30	Exhaled carbon monoxide in childhood asthma. ( Barnes, PJ; James, A; Jatakanon, A; Kharitonov, SA; Uasuf, CG; Wilson, NM, 1999)
"Studies of Dco in bronchial asthma have yielded conflicting results."	5.29	Single breath diffusing capacity for carbon monoxide in stable asthma. ( Collard, P; Frans, A; Keyeux, A; Nejadnik, B; Njinou, B, 1994)
"The aim of this study was to assess the effect of oral prednisone treatment on FE(NO) and ECO levels in a group of 30 asthmatic children with asthma exacerbation."	5.10	Exhaled carbon monoxide levels after a course of oral prednisone in children with asthma exacerbation. ( Baraldi, E; Landi, L; Scollo, M; Zacchello, F; Zanconato, S; Zaramella, C, 2002)
"The pectoralis muscle is an important indicator of respiratory muscle function and has been linked to various parenchymal biomarkers, such as airflow limitation severity and diffusing capacity for carbon monoxide, which are widely used in diagnosing parenchymal diseases, including asthma and chronic obstructive pulmonary disease."	4.31	Deep learning-based pectoralis muscle volume segmentation method from chest computed tomography image using sagittal range detection and axial slice-based segmentation. ( Choi, I; Choi, J; Jung, J; Ryu, M; Yang, Z; Yong, HS, 2023)
"This study was performed to investigate the relationship between the hospitalization rate for asthma and the ambient carbon monoxide (CO) by examining regional variation of the hospitalization rates for asthma in Korea and its factors."	3.96	Regional Variation of Hospitalization Rates for Asthma in Korea: Association with Ambient Carbon Monoxide and Health Care Supply. ( Kang, S; Kim, AM; Kim, Y; Park, JH, 2020)
"Lung function measures (FEV1% 77 vs 84, FEV1/FVC% 85 vs 91, FEF50% 61 vs 80) and carbon monoxide diffusion capacity (DLCO%, 81 vs 88) were all reduced in children with BPD compared to asthma (P values <0."	3.85	Differences and similarities between bronchopulmonary dysplasia and asthma in schoolchildren. ( Broström, EB; Ebersjö, C; Hedlin, G; James, A; Nordlund, B, 2017)
"We analyzed the trends of emphysema, asthma, and pneumonia mortality and changes of the levels of ozone, sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and particulate matters (PM2."	3.80	Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality. ( Abernethy, AP; Akushevich, I; Holman, S; Kravchenko, J; Lyerly, HK; Ross, WG, 2014)
"Interquartile range increases in ultrafine particles and carbon monoxide concentrations in the previous 7 days were associated with increases in the relative odds of a pediatric asthma visit, with the largest increases observed for 4-day mean ultrafine particles (interquartile range=2088p/cm(3); OR=1."	3.80	Increased ultrafine particles and carbon monoxide concentrations are associated with asthma exacerbation among urban children. ( Evans, KA; Fagnano, M; Halterman, JS; Hopke, PK; Rich, DQ, 2014)
"5) and exhaled carbon monoxide (eCO) measured in non-asthmatic children."	3.79	Dose-dependent relationship between prenatal exposure to fine particulates and exhaled carbon monoxide in non-asthmatic children. A population-based birth cohort study. ( Flak, E; Jacek, R; Jędrychowski, WA; Klimaszewska-Rembiasz, M; Maugeri, U; Mróz, E; Sowa, A; Spengler, J, 2013)
"The concentration of exhaled carbon monoxide (eCO) in young children with stable asthma and during acute asthma attack is not known."	3.78	Exhaled carbon monoxide levels in preschool-age children with episodic asthma. ( Arai, H; Asamura, T; Morikawa, T; Ohara, T; Ohara, Y; Ohrui, T; Sasaki, H, 2012)
"Exhaled carbon monoxide and nitric oxide reflect allergic inflammation in asthma and have clinical utility for monitoring disease severity."	3.76	Bronchoprovocation testing in asthma: effect on exhaled monoxides. ( Calhoun, WJ; Choi, AM; Dinella, JV; Patel, SA; Sethi, JM; White, AM, 2010)
" Asthmatics showed increased levels of FeNO, exhaled carbon monoxide, total serum IgE, and higher eosinophilia."	3.75	Factors attributable to the level of exhaled nitric oxide in asthmatic children. ( Babusikova, E; Banovcin, P; Barreto, M; Fabry, J; Jesenak, M; Michnova, Z; Mikler, J; Nosal, S, 2009)
"To evaluate the relationship between exposure to gaseous air pollutants (ozone [O3], carbon monoxide [CO], nitrogen dioxide [NO2], and sulfur dioxide [SO2]) socioeconomic status and the prevalence of symptoms of asthma, rhinitis and atopic eczema in adolescents."	3.74	Prevalence of symptoms of asthma, rhinitis, and atopic eczema in Brazilian adolescents related to exposure to gaseous air pollutants and socioeconomic status. ( Camelo-Nunes, IC; Fischer, GB; Gonzalez, C; Jacob, CM; Naspitz, CK; Pastorino, AC; Rosário Filho, NA; Solé, D; Wandalsen, GF; Wandalsen, NF, 2007)
"A study was conducted to evaluate the role of exhaled carbon monoxide (CO) levels in the management of patients with mild and moderate persistent bronchial asthma."	3.74	Exhaled carbon monoxide levels: as a marker of clinical severity and control of asthma. ( Grover, RS; Kumar, R, 2008)
"Carbon monoxide (CO) can be detected in exhaled air and is increased in adult and childhood persistent asthmatic patients."	3.73	Exhaled carbon monoxide levels in school-age children with episodic asthma. ( He, M; Morikawa, T; Ohara, Y; Ohrui, T; Sasaki, H; Yamaya, M; Yasuda, H, 2006)
"The smoking history, FeNO, and fractional concentration of carbon monoxide in exhaled breath (FeCO) were measured in 53 subjects with asthma and 51 control subjects."	3.73	Short and long-term effects of cigarette smoking independently influence exhaled nitric oxide concentration in asthma. ( Chaudhuri, R; Fraser, I; Livingston, E; McKay, IC; McSharry, CP; Thomson, NC, 2005)
"Exhaled nitric oxide (eNO) and carbon monoxide (eCO) concentrations are elevated in inflammatory airway diseases like asthma and have been investigated as potential diagnostic markers."	3.72	Exhaled carbon monoxide is not flow dependent in children with cystic fibrosis and asthma. ( Beck-Ripp, J; Griese, M; Latzin, P, 2004)
"The study showed positive relations between gaseous pollutants (carbon monoxide, sulphur dioxide, and nitrogen dioxide) at comparatively low levels and asthma hospitalisation in children, using bi-directional case-crossover analyses."	3.72	Effect of short-term exposure to gaseous pollution on asthma hospitalisation in children: a bi-directional case-crossover analysis. ( Burnett, RT; Chen, Y; Krewski, D; Lin, M; Villeneuve, PJ, 2003)
"Three hundred thirty-one consecutive outpatients (161 with asthma and 170 with COPD) were examined cross-sectionally by self-reported smoking status, breath CO monitoring, and serum cotinine concentration."	3.72	Optimal cutoff level of breath carbon monoxide for assessing smoking status in patients with asthma and COPD. ( Hajiro, T; Koyama, H; Mishima, M; Nishimura, K; Oga, T; Sato, S; Tsukino, M, 2003)
"The study objectives were to analyze the changes in exhaled carbon monoxide (COex) induced by histamine provocation challenge in asthmatic patients and to evaluate the relationship between COex and airway sensitivity and reactivity."	3.72	Relationship between exhaled carbon monoxide and airway hyperresponsiveness in asthmatic patients. ( García-Río, F; Pino, JM; Prados, C; Ramirez, M; Villamor, J; Viñas, A, 2004)
"Increased levels of exhaled carbon monoxide (fractional concentration of CO in expired gas (FE,CO)), measured with an electrochemical sensor, have been reported in patients with inflammatory airway disorders, such as asthma, rhinitis and cystic fibrosis."	3.71	Exhaled carbon monoxide is not elevated in patients with asthma or cystic fibrosis. ( Alving, K; Ihre, E; Johannesson, M; Lundberg, JO; Marteus, H; Nordval, SL; Zetterquist, W, 2002)
"Exhaled carbon monoxide is a useful marker of airway inflammation in untreated asthma."	3.71	An assessment of the role of exhaled carbon monoxide in acute asthmatic exacerbations in hospitalised patients. ( Chan, CC; Kong, PM; Lee, P; Wang, YT, 2002)
"Exhaled carbon monoxide (CO) concentrations were measured on a CO monitor by vital capacity maneuvers in asthmatic patients either receiving or not receiving inhaled corticosteroids, and in nonsmoking healthy control subjects."	3.71	[Detection of exhaled CO as a simple non-invasive tool for monitoring acute exacerbations of asthma in the elderly]. ( Ohrui, T; Okinaga, S; Sasaki, H; Yamada, N; Yamaya, M; Yanai, M, 2001)
"Carbon monoxide (CO) can be detected in exhaled air and is increased in asthmatic patients not treated with corticosteroids."	3.71	Relation between exhaled carbon monoxide levels and clinical severity of asthma. ( Hosoda, M; Ishizuka, S; Matsui, T; Monma, M; Sasaki, H; Sekizawa, K; Suzuki, T; Yamaya, M, 2001)
"Carbon monoxide (CO) generated by catalysis of heme by heme oxygenase is increased in the exhaled air of asthmatic patients."	3.71	Carbon monoxide attenuates aeroallergen-induced inflammation in mice. ( Chapman, JT; Choi, AM; Elias, JA; Otterbein, LE, 2001)
"The source of exhaled carbon monoxide (CO) and the relationship to airway inflammation are not clear."	3.71	Alterations in exhaled gas profile during allergen-induced asthmatic response. ( Dweik, RA; Erzurum, SC; Hammel, J; Khatri, SB; Laskowski, D; McCarthy, K; Ozkan, M, 2001)
"Exhaled CO and sputum bilirubin levels were measured and HO-1 protein expression in airway macrophages was determined by Western blotting in asthmatic patients as levels of oxidants are raised in asthma and may induce HO-1."	3.70	Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress. ( Barnes, PJ; Donnelly, LE; Horváth, I; Kharitonov, SA; Kiss, A; Paredi, P, 1998)
"Carbon monoxide is known to be present in measurable quantities in the exhaled air of normal subjects and at higher concentrations in asthmatic patients not treated with glucocorticoids."	3.70	Exhaled carbon monoxide levels during treatment of acute asthma. ( Ishizuka, S; Monma, M; Sasaki, H; Sekizawa, K; Yamara, M; Yamaya, M, 1999)
"Positive associations, weakly significant and consistent across lags, were observed between asthma consultations and nitrogen dioxide (NO2) and carbon monoxide (CO) in children and particulate matter of less than 10 microm in diameter (PM10) in adults, and between other LRD consultations and sulphur dioxide (SO2) in children."	3.70	Association of air pollution with daily GP consultations for asthma and other lower respiratory conditions in London. ( Anderson, HR; Atkinson, RW; Goubet, SA; Haines, A; Hajat, S, 1999)
"The bronchoalveolar lavage cellular constituents of patients with sulfur mustard gas-induced asthma and chronic bronchitis are similar to those that have been observed previously in patients with asthma and chronic bronchitis from other common causes."	3.70	Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis. ( Emad, A; Rezaian, GR, 1999)
"Increased air stagnation was shown to be a surrogate for accumulation of the products of incomplete combustion, including carbon monoxide and fine particulate levels of organic and elemental carbon, and was more strongly associated with asthma aggravation than any one of the measured pollutants."	3.70	Asthma aggravation, combustion, and stagnant air. ( Claiborn, C; Finn, D; Koenig, J; Larson, T; Norris, G; Sheppard, L, 2000)
"To investigate the role of carbon monoxide (CO) in the pathogenesis of asthma."	3.70	[Evidence of increased endogenous carbon monoxide production in asthma]. ( Jiang, D; Li, H; Shi, Y, 1999)
"Exhaled carbon monoxide (CO) concentrations were measured on a CO monitor by vital capacity maneuvers in asthmatic patients receiving or not receiving inhaled corticosteroids and in nonsmoking and smoking healthy control subjects."	3.69	Increased carbon monoxide in exhaled air of asthmatic patients. ( Ohrui, T; Okinaga, S; Sasaki, H; Sekizawa, K; Yamaya, M; Zayasu, K, 1997)
"The aim of this study was to test the hypothesis that carbon monoxide diffusing capacity (DCO) is elevated in asthmatic patients with minimal airflow limitation and/or hyperinflation; the latter factors should reduce the possibility of technical errors in the measurement of DCO."	3.67	Carbon monoxide diffusing capacity in asthmatic patients with mild airflow limitation. ( Stewart, RI, 1988)
"To explain why the single-breath carbon monoxide diffusing capacity (Dsb) was, on the average, elevated in 163 asthmatic subjects and 175 patients with cystic fibrosis, we simulated this elevation in ten normal subjects by having them perform the test for Dsb through an inspiratory obstruction."	3.66	Evaluation of the single-breath diffusing capacity in asthma and cystic fibrosis. ( Bryan, AC; Hyland, RH; Keens, TG; Krastins, IR; Levison, H; Mansell, A; Zamel, N, 1979)
"We studied patients with asthma or COPD from Czechia, Ireland, and Spain."	3.01	Lung function changes in patients with chronic obstructive pulmonary disease (COPD) and asthma exposed to secondhand smoke in outdoor areas. ( Alonso, T; Boffi, R; Clancy, L; Fernández, E; Gallus, S; Gorini, G; Keogan, S; López, MJ; López-Nicolás, Á; Radu-Loghin, C; Semple, S; Soriano, JB; Sunday, S; Tigova, O; Tzortzi, A, 2021)
"Patients with type 2 diabetes continued taking their prestudy oral antihyperglycemic medication."	2.74	Safety and efficacy of AIR inhaled insulin compared with subcutaneous insulin in patients having diabetes and asthma: A 12-month, randomized, noninferiority trial. ( Ang, E; Berclaz, PY; Ferguson, JA; Heilmann, CR; Lawrence, MK; Tobian, JA; Webb, DM, 2009)
"In 20 patients with bronchial asthma the Hb-CO concentration decreased after 3 weeks of treatment with oral glucocorticoids (p<0."	2.70	Increased blood carboxyhaemoglobin concentrations in inflammatory pulmonary diseases. ( Ohrui, T; Sasaki, H; Yamaya, M; Yanai, M; Yasuda, H, 2002)
"Hydrogen sulfide (H2S)has emerged as pivotal signaling molecules since it is recognized as the third gasotransmitter together with nitric oxide and carbon monoxide."	2.55	[The Molecular Switches and Atomic Biological Mechanisms Underlying the Physiological and Pathophysio-logical Effects of Hydrogen Sulfide to Regulate Its "Receptors"]. ( Cai, WJ; Li, XH; Tao, BB; Wang, MJ; Xue, WL; Zhu, YC, 2017)
"(2) There is a valid definition for COPD."	2.49	A challenge to the seven widely believed concepts of COPD. ( Al-Kassimi, FA; Alhamad, EH, 2013)
"Alveolar NO is increased in chronic obstructive pulmonary disease (COPD), reflecting disease severity and progression."	2.42	Effects of corticosteroids on noninvasive biomarkers of inflammation in asthma and chronic obstructive pulmonary disease. ( Barnes, PJ; Kharitonov, SA, 2004)
"Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) patients experience exacerbations more frequently than those with asthma or COPD alone."	1.72	The association between transfer coefficient of the lung and the risk of exacerbation in asthma-COPD overlap: an observational cohort study. ( Aso, H; Enokizu-Ogawa, A; Ishimatsu, A; Jingushi, Y; Katahira, K; Moriwaki, A; Nogami, H; Ogata, H; Taguchi, K; Yoshida, M, 2022)
"The development of COPD features, such as an incomplete reversibility of airway obstruction (IRAO), in smoking or non-smoking asthmatic patients, a condition often named Asthma-COPD Overlap (ACO), has been recognized for decades."	1.48	Asthma-COPD Overlap Phenotypes and Smoking :Comparative features of asthma in smoking or non-smoking patients with an incomplete reversibility of airway obstruction. ( Bilodeau, L; Boulay, MÈ; Boulet, LP; Dérival, JL; Lepage, J; Maltais, F; Milot, J, 2018)
"Ozone (O₃) was associated with a 13-22% increased risk of stillbirth on days 2, 3, and 5-7 prior to delivery in single pollutant models, and these findings persisted in multi-pollutant models for days 5 (RR = 1."	1.46	Chronic and Acute Ozone Exposure in the Week Prior to Delivery Is Associated with the Risk of Stillbirth. ( Ha, S; Kim, SS; Liu, D; Mendola, P; Pollack, AZ; Seeni, I; Sherman, S; Zhu, Y, 2017)
"Hospital admissions for RD including chronic obstructive pulmonary disease (COPD), asthma, and pneumonia, and ambient air pollution data levels for Kaohsiung were obtained for the period from 2006 to 2010."	1.42	Coarse Particulate Air Pollution Associated with Increased Risk of Hospital Admissions for Respiratory Diseases in a Tropical City, Kaohsiung, Taiwan. ( Cheng, MH; Chiu, HF; Yang, CY, 2015)
"From CSSR acquisitions, the COPD subjects showed red blood cell to tissue-plasma (RBC-to-TP) ratios below the average for the healthy subjects (p < 0."	1.40	Assessment of lung function in asthma and COPD using hyperpolarized 129Xe chemical shift saturation recovery spectroscopy and dissolved-phase MRI. ( Altes, TA; Hersman, FW; Jiang, Y; Mata, JF; Miller, GW; Mugler, JP; Qing, K; Ruppert, K; Ruset, IC, 2014)
"Bronchial asthma is characterised by chronic airway inflammation commonly associated with increased oxidative stress."	1.40	Factors influencing the levels of exhaled carbon monoxide in asthmatic children. ( Babusikova, E; Banovcin, P; Dobrota, D; Havlicekova, Z; Jesenak, M, 2014)
"Ozone exposure was significantly associated with the 12-month prevalence of wheeze (odds ratio per 5 ppb, 1."	1.37	Association of ozone exposure with asthma, allergic rhinitis, and allergic sensitization. ( Ha, M; Hong, SJ; Hong, YC; Kang, DM; Kim, BJ; Kim, HB; Kim, HC; Kim, SY; Kwon, HJ; Kwon, JW; Lee, CG; Lee, SY; Leem, JH; Park, KS; Sakong, J; Seo, JH; Yu, J, 2011)
"Patients in asthma or COPD exacerbations were evaluated twice-during the exacerbation and at a follow-up visit-to compare variations in breath biomarkers during these events."	1.37	Clinical study of multiple breath biomarkers of asthma and COPD (NO, CO(2), CO and N(2)O) by infrared laser spectroscopy. ( McManus, JB; Milton, DK; Nelson, DD; Sama, SR; Shorter, JH; Zahniser, MS, 2011)
"The study showed more often allergy, bronchial asthma and respiratory tract infections in the group of children exposed to passive smoking cigarettes at home in comparison with the group of children without this exposure."	1.32	[Effect of passive cigarette smoking on the frequency of respiratory tract infections, allergy and bronchial asthma in children]. ( Bujnowska-Fedak, M; Piorek, M; Pirogowicz, I; Steciwko, A, 2004)
"To estimate the prevalence of bronchial asthma (BA) basing on the complex of the disease symptoms within the last year associated with bronchial obstruction (BO) and bronchial hyperreactivity (BHR)."	1.30	[Epidemiology of bronchial asthma in a large industrial region]. ( Chirkov, VI; Leshchenko, IV; Livshits, AA, 1998)
"Carbon monoxide is a product of haem degradation by haem oxygenase (HO), activated by inflammatory cytokines and oxidants."	1.30	Changes in exhaled carbon monoxide and nitric oxide levels following allergen challenge in patients with asthma. ( Allegra, L; Barnes, PJ; Horvath, I; Kharitonov, SA; Leckie, MJ; Paredi, P, 1999)
"We also studied whether upper respiratory tract infections were associated with elevated exhaled CO."	1.30	Exhaled carbon monoxide in childhood asthma. ( Barnes, PJ; James, A; Jatakanon, A; Kharitonov, SA; Uasuf, CG; Wilson, NM, 1999)
"Studies of Dco in bronchial asthma have yielded conflicting results."	1.29	Single breath diffusing capacity for carbon monoxide in stable asthma. ( Collard, P; Frans, A; Keyeux, A; Nejadnik, B; Njinou, B, 1994)
"The most important results were a respiratory acidosis after intubation and simultaneous hyperoxigenation during controlled (manual) ventilation."	1.28	[Laboratory diagnostic monitoring of blood gas parameters in children during bronchologic studies]. ( Augst, D; Ballke, EH; Maass, B; Wiersbitzky, S; Zöllner, H, 1990)

Research

Studies (216)

Authors

Clinical Trials (7)

Trial Overview

Trial Outcomes

Composite Asthma Severity Index

Timeframe	Studies, this research(%)	All Research%
pre-1990	49 (22.69)	18.7374
1990's	26 (12.04)	18.2507
2000's	64 (29.63)	29.6817
2010's	59 (27.31)	24.3611
2020's	18 (8.33)	2.80

Authors	Studies
Ogata, H	1
Katahira, K	1
Enokizu-Ogawa, A	1
Jingushi, Y	1
Ishimatsu, A	1
Taguchi, K	1
Nogami, H	1
Aso, H	1
Moriwaki, A	1
Yoshida, M	1
Peng, J	1
Wang, M	1
Wu, Y	1
Shen, Y	1
Chen, L	1
Pak, C	1
Cowl, CT	1
Kim, JH	2
Kang, BJ	1
Lee, T	1
Jegal, Y	1
Ra, SW	1
Kim, Y	2
Song, J	1
Qiu, W	1
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Trial	Phase	Enrollment	Study Type	Start Date	Status
School Inner-City Asthma Intervention Study[NCT02291302]		236 participants (Actual)	Interventional	2015-01-31	Completed
School-Based Asthma Therapy: Stage 2 Effectiveness Study[NCT01175369]		530 participants (Actual)	Interventional	2006-08-31	Completed
Hyperpolarized Xenon-129 MRI: a New Multi-dimensional Biomarker to Determine Pulmonary Physiologic Responses to COPD Therapeutics[NCT03002389]	Phase 2	95 participants (Anticipated)	Interventional	2017-11-05	Recruiting
A Pivotal, Open-Label, Parallel Study to Evaluate the Safety and Efficacy of Human Insulin Inhalation Powder (HIIP) Compared to Injectable Insulin in Patients With Diabetes and COPD or Asthma[NCT00157339]	Phase 3	299 participants (Actual)	Interventional	2005-08-31	Completed
Childhood Asthma Management Program[NCT00000575]	Phase 3	1,041 participants (Actual)	Interventional	1991-09-30	Completed
Adjuvant Therapy for Severe Asthma by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study on Effectiveness and Safety[NCT02883582]		150 participants (Anticipated)	Interventional	2016-08-31	Recruiting
Asthma Inflammation Research[NCT01536522]	Early Phase 1	60 participants (Anticipated)	Interventional	2011-01-31	Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

[a comprehensive severity scale of day symptoms and albuterol use, night symptoms and albuterol use, controller treatment, lung function measures, and exacerbations], health care utilization, and pulmonary function testing (PFT's) including FEV1; FEV1/FVC, FEF25-75. CASI ranges from 0 (lowest) -20 points (highest) with a minimal clinically important difference of 0.49 points. The higher score is worse outcome. (NCT02291302)
Timeframe: 12 months

Lung Function

Intervention	score on a scale (Mean)
Environmental Intervention	2.9
Sham and Control (Control)	2.8
Active Air Purifier and Control	3.1
Sham and Inegrated Pest	2.9

Spirometry measure of forced expiration volume in 1 second (NCT02291302)
Timeframe: 12 months

Maximum Number of Days With Asthma Symptoms Within 2 Weeks

Intervention	percentage of predicted (Mean)
Environmental Intervention	95.5
Sham and Control (Control)	99.2
Active Air Purifier and Control	97
Sham and Inegrated Pest	94.9

"Maximum number of~Days with wheezing, tightness in the chest, or cough and/or~Nights with disturbed sleep as a result of asthma and/or~Days on which the child had to slow down or discontinue play activities because of asthma This is defined as a cumulative assessment from the different variables listed in the Measure Description" (NCT02291302)
Timeframe: up to 12 months

School Absences

Intervention	days (Mean)
Environmental Intervention	2.2
Sham and Control (Control)	2.7
Active Air Purifier and Control	1.2
Sham and Inegrated Pest	2.1

Number of school days missed because of asthma/ 2 weeks (NCT02291302)
Timeframe: 12 months

Number of Symptom Free Days

Intervention	days/2 weeks (Mean)
Environmental Intervention	0.15
Sham and Control (Control)	0.18
Active Air Purifier and Control	0.16
Sham and Inegrated Pest	0.07

The primary outcome variable is the average number of symptom free days over 2 weeks assessed during peak asthma season (data collected during November, December, January and February during the school year). (NCT01175369)
Timeframe: Average Symptom Free Days, over 2 weeks, during peak asthma season (November-February)

Bronchial Responsiveness to Serial Methacholine Concentrations Inhaled Into the Lungs

Intervention	Days (Mean)
Usual Care	10.7
School-based Care	11.6

Bronchial responsiveness to serial concentrations of inhaled methacholine solution (mg/ml) as measured by serial ratios of follow-up to baseline FEV1 (forced volume of air expired from the lungs in one second). A dose-response curve is calculated from the serial ratios in relation to the serial concentrations to determine PC20, the concentration associated with a 20% drop from baseline in FEV1; this PC20 is the outcome measure with units mg/ml of methacholine. (NCT00000575)
Timeframe: 4-6 years from baseline

Change From Baseline in the Rate of Asthma Free Days

Intervention	mg/ml of methacholine (Geometric Mean)
1 Budesonide	3.0
2 Nedocromil	1.8
3 Placebo	1.9

Change from baseline proportion of days without asthma symptoms or other asthma related events to proportion of days during the 4-6 years of follow-up. Asthma free days were determined from daily asthma diaries kept from baseline to the end of treatment, 4-6 years later. (NCT00000575)
Timeframe: 4-6 years from baseline

Change in Height From Baseline to End of Treatment, 4-6 Years Later

Intervention	days per month (Mean)
1 Budesonide	11.3
2 Nedocromil	9.3
3 Placebo	9.3

Change in standing height from baseline to end of treatment. Standing height is measured three times without shoes using a calibrated Harpenden stadiometer; the average of the three repeated heights to the nearest 0.1 cm is the height measure at either baseline or end of treatment. (NCT00000575)
Timeframe: 4-6 years from baseline

Mortality

Need for Urgent Care for Asthma

Intervention	cm (Mean)
1 Budesonide	22.7
2 Nedocromil	23.7
3 Placebo	23.8

Intervention	participants (Number)
1 Budesonide	0
2 Nedocromil	1
3 Placebo	0

Counts during the period of treatment (4-6 years) of visits to emergency rooms or equivalent urgent care settings for asthma treatment. (NCT00000575)
Timeframe: 4-6 years from baseline

Pulmonary Function as Measured by Normalized FEV1 Over a 4-6 Year Period

Intervention	rate per 100 person years (Number)
1 Budesonide	12
2 Nedocromil	16
3 Placebo	22

Change in FEV1 % of predicted, post-bronchodilator use, from baseline to the end of treatment (4-6 years after randomization). Percent predicted determined from three separate published sets of reference equations for white, black, and Hispanic children - see NEJM 343: 1054-1062, 2000 for more details and references. (NCT00000575)
Timeframe: At the end of treatment, 4-6 years from baseline assessment

Standardized Depression Scale -- Children's Depression Inventory

Intervention	percentage of predicted value (Mean)
1 Budesonide	0.6
2 Nedocromil	-0.5
3 Placebo	-0.1

Change in total score on the Children's Depression Inventory from baseline to the end of treatment, 4-6 years later. The total score ranges from 0-54 with higher scores indicating greater levels of depression. (NCT00000575)
Timeframe: 4-6 years from baseline

Article	Year
Clinical Indicators for Asthma-COPD Overlap: A Systematic Review and Meta-Analysis. International journal of chronic obstructive pulmonary disease, 2022, Volume: 17 Topics: Asthma; Carbon Monoxide; Chitinase-3-Like Protein 1; Forced Expiratory Volume; Humans; Immunoglobuli	2022
Health risks associated with the production and usage of charcoal: a systematic review. BMJ open, 2023, 07-24, Volume: 13, Issue:7 Topics: Asthma; Blood Pressure; Carbon Monoxide; Carbon Monoxide Poisoning; Charcoal; Humans	2023
Association of outdoor air pollution with the prevalence of asthma in children of Latin America and the Caribbean: A systematic review and meta-analysis. The Journal of asthma : official journal of the Association for the Care of Asthma, 2018, Volume: 55, Issue:11 Topics: Adolescent; Age Factors; Air Pollution; Asthma; Carbon Monoxide; Caribbean Region; Child; Child, Pre	2018
[The Molecular Switches and Atomic Biological Mechanisms Underlying the Physiological and Pathophysio-logical Effects of Hydrogen Sulfide to Regulate Its "Receptors"]. Sheng li ke xue jin zhan [Progress in physiology], 2017, Volume: 48, Issue:1 Topics: Asthma; Atherosclerosis; Carbon Monoxide; Cardiovascular System; Humans; Hydrogen Sulfide; Hypertens	2017
Carbon monoxide in exhaled breath testing and therapeutics. Journal of breath research, 2013, Volume: 7, Issue:1 Topics: Acute Lung Injury; Anesthesia; Animals; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Cystic Fi	2013
A meta-analysis of the association of exhaled carbon monoxide on asthma and allergic rhinitis. Clinical reviews in allergy & immunology, 2011, Volume: 41, Issue:1 Topics: Adolescent; Adrenal Cortex Hormones; Adult; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Child	2011
Exhaled carbon monoxide in asthmatics: a meta-analysis. Respiratory research, 2010, Apr-30, Volume: 11 Topics: Adult; Anti-Asthmatic Agents; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Child; Exhalation;	2010
Update in environmental and occupational medicine 2010. American journal of respiratory and critical care medicine, 2011, Jun-15, Volume: 183, Issue:12 Topics: Air Pollution; Asthma; Biomass; Carbon Monoxide; Cardiovascular Diseases; Humans; Lung Diseases; Occ	2011
Motor vehicle air pollution and asthma in children: a meta-analysis. Environmental research, 2012, Volume: 117 Topics: Asthma; Carbon Monoxide; Child; Environmental Exposure; Humans; Nitrogen Dioxide; Nitrous Oxide; Odd	2012
Breath biomarkers in diagnosis of pulmonary diseases. Clinica chimica acta; international journal of clinical chemistry, 2012, Nov-12, Volume: 413, Issue:21-22 Topics: Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Cystic Fibrosis; Humans; Hydrogen Peroxide; Lung	2012
A challenge to the seven widely believed concepts of COPD. International journal of chronic obstructive pulmonary disease, 2013, Volume: 8 Topics: Asthma; Basement Membrane; Biopsy; Bronchi; Bronchiectasis; Bronchoscopy; Carbon Monoxide; Diagnosis	2013
Analysis of expired air for oxidation products. American journal of respiratory and critical care medicine, 2002, Dec-15, Volume: 166, Issue:12 Pt 2 Topics: Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Cystic Fibrosis; Humans; Hydrocarbons; Lipid Pero	2002
Continual emerging roles of HO-1: protection against airway inflammation. American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:1 Topics: Asthma; Carbon Monoxide; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Membrane Proteins;	2004
[Exhaled nitric oxide (NO), carbon monoxide (CO)]. Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 12 Topics: Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Humans; Nitric Oxide; Pulmonary Disease, Chronic	2004
Effects of corticosteroids on noninvasive biomarkers of inflammation in asthma and chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society, 2004, Volume: 1, Issue:3 Topics: Administration, Inhalation; Adrenal Cortex Hormones; Asthma; Biomarkers; Breath Tests; Carbon Monoxi	2004
[Nitric oxide and its related compounds]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8 Topics: Asthma; Biomarkers; Carbon Monoxide; Chromatography, Gas; Chromatography, High Pressure Liquid; Clin	2005
Therapeutic applications of carbon monoxide in lung disease. Current opinion in pharmacology, 2006, Volume: 6, Issue:3 Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Apoptosis; Asthma; Bleomycin; Carbon	2006
Indoor environmental influences on children's asthma. Pediatric clinics of North America, 2007, Volume: 54, Issue:1 Topics: Air Pollution, Indoor; Animals; Asthma; Carbon Monoxide; Cats; Child; Cockroaches; Dogs; Environment	2007
[Exhaled breath condensate in the assessment of airway inflammation]. Przeglad lekarski, 2006, Volume: 63, Issue:12 Topics: Adult; Ammonia; Asthma; Biomarkers; Breath Tests; Bronchitis; Carbon Monoxide; Child; Diagnosis, Dif	2006
Health effects of outdoor air pollution. Committee of the Environmental and Occupational Health Assembly of the American Thoracic Society. American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:1 Topics: Adult; Aerosols; Air Pollutants; Air Pollution; Animals; Asthma; Biomarkers; Bronchial Hyperreactivi	1996
Gas analysis. American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:2 Pt 2 Topics: Adult; Age Factors; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Child; Cystic Fibrosis; Elect	2000
[Respiratory function in the obese subject]. Revue de pneumologie clinique, 2002, Volume: 58, Issue:2 Topics: Asthma; Carbon Monoxide; Humans; Hypoxia; Lung Compliance; Obesity; Pulmonary Ventilation; Respirati	2002
Air pollution: its effects on health and respiratory disease--a review. Annals of allergy, 1977, Volume: 39, Issue:4 Topics: Air Pollution; Asthma; Bronchitis; Carbon Monoxide; Chronic Disease; Hydrocarbons; Meteorological Co	1977
Indoor air pollution. Clinics in chest medicine, 1992, Volume: 13, Issue:2 Topics: Air Pollutants; Air Pollution, Indoor; Allergens; Alveolitis, Extrinsic Allergic; Asthma; Carbon Mon	1992
[Medico-social aspects of air pollution]. Minerva medica, 1971, Mar-03, Volume: 62, Issue:18 Topics: Air Pollution; Asthma; Benzopyrenes; Bronchitis; Carbon Dioxide; Carbon Monoxide; Dust; Environmenta	1971

Article	Year
The association between transfer coefficient of the lung and the risk of exacerbation in asthma-COPD overlap: an observational cohort study. BMC pulmonary medicine, 2022, Jan-12, Volume: 22, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Asthma; Carbon Monoxide; Cohort Studies; Female; Forced Expiratory V	2022
Reduced Diffusing Capacity in Humidifier Disinfectant-Associated Asthma Versus Typical Asthma: A Retrospective Case Control Study. Journal of Korean medical science, 2022, Nov-14, Volume: 37, Issue:44 Topics: Asthma; Carbon Monoxide; Case-Control Studies; Disinfectants; Humans; Humidifiers; Lung; Retrospecti	2022
Association of ambient carbon monoxide exposure with hospitalization risk for respiratory diseases: A time series study in Ganzhou, China. Frontiers in public health, 2023, Volume: 11 Topics: Asthma; Carbon Monoxide; China; Female; Hospitalization; Humans; Influenza, Human; Pulmonary Disease	2023
Isolated abnormal diffusing capacity for carbon monoxide (iso↓DLco) is associated with increased respiratory symptom burden in people with HIV infection. PloS one, 2023, Volume: 18, Issue:7 Topics: Asthma; Carbon Monoxide; Cross-Sectional Studies; Forced Expiratory Volume; HIV Infections; Humans;	2023
Deep learning-based pectoralis muscle volume segmentation method from chest computed tomography image using sagittal range detection and axial slice-based segmentation. PloS one, 2023, Volume: 18, Issue:9 Topics: Asthma; Carbon Monoxide; Deep Learning; Humans; Pectoralis Muscles; Tomography, X-Ray Computed	2023
Ambient carbon monoxide and relative risk of daily hospital outpatient visits for respiratory diseases in Lanzhou, China. International journal of biometeorology, 2023, Volume: 67, Issue:12 Topics: Air Pollutants; Air Pollution; Asthma; Bronchitis; Carbon Monoxide; Child; China; Female; Hospitals;	2023
Case 323. Radiology, 2023, Volume: 309, Issue:2 Topics: Aged; Asthma; Carbon Monoxide; Cone-Beam Computed Tomography; Cough; Female; Heart Rate; Humans	2023
Regional Variation of Hospitalization Rates for Asthma in Korea: Association with Ambient Carbon Monoxide and Health Care Supply. International journal of environmental research and public health, 2020, 02-14, Volume: 17, Issue:4 Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Environmental Exposure; Female; Hospitalizat	2020
Acute Effects of Air Pollution on Hospital Admissions for Asthma, COPD, and Bronchiectasis in Ahvaz, Iran. International journal of chronic obstructive pulmonary disease, 2020, Volume: 15 Topics: Age Factors; Air Pollutants; Air Pollution; Asthma; Bronchiectasis; Carbon Monoxide; Hospitalization	2020
Exhaled carbon monoxide levels in infants and toddlers with episodic asthma. Fukushima journal of medical science, 2020, Aug-04, Volume: 66, Issue:2 Topics: Asthma; Breath Tests; Carbon Monoxide; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Ma	2020
Spatiotemporal variations of asthma admission rates and their relationship with environmental factors in Guangxi, China. BMJ open, 2020, 10-07, Volume: 10, Issue:10 Topics: Adolescent; Adult; Aged; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child; Child, Presc	2020
Assessing the applicability of the new Global Lung Function Initiative reference values for the diffusing capacity of the lung for carbon monoxide in a large population set. PloS one, 2021, Volume: 16, Issue:1 Topics: Adult; Aged; Asthma; Bronchitis; Carbon Monoxide; Cystic Fibrosis; Female; Humans; Lung; Lung Diseas	2021
Asthma-prone areas modeling using a machine learning model. Scientific reports, 2021, 01-21, Volume: 11, Issue:1 Topics: Adolescent; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child; Environmental Exposure; E	2021
Differences and similarities between bronchopulmonary dysplasia and asthma in schoolchildren. Pediatric pulmonology, 2017, Volume: 52, Issue:9 Topics: Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Bronchopulmonary Dysplasia; Carbon Monoxide	2017
Chronic and Acute Ozone Exposure in the Week Prior to Delivery Is Associated with the Risk of Stillbirth. International journal of environmental research and public health, 2017, 07-06, Volume: 14, Issue:7 Topics: Adult; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Environmental Exposure; Female; Human	2017
Exposure to Mobile Source Air Pollution in Early-life and Childhood Asthma Incidence: The Kaiser Air Pollution and Pediatric Asthma Study. Epidemiology (Cambridge, Mass.), 2018, Volume: 29, Issue:1 Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child; Child, Preschool; Cohort Studies; Env	2018
Ambient air pollution and emergency department visits for asthma in Erie County, New York 2007-2012. International archives of occupational and environmental health, 2018, Volume: 91, Issue:2 Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Emergency Service, Hospital; Environmental E	2018
Lifetime exposure to particulate air pollutants is negatively associated with lung function in non-asthmatic children. Environmental pollution (Barking, Essex : 1987), 2018, Volume: 236 Topics: Adolescent; Asthma; Carbon Monoxide; Child; Environmental Exposure; Female; Humans; Lung; Male; Nitr	2018
Exposure to NO Clinical epigenetics, 2018, Volume: 10 Topics: Adolescent; Asthma; California; Carbon Monoxide; CpG Islands; DNA Methylation; Epigenesis, Genetic;	2018
Impact evaluation of environmental factors on respiratory function of asthma patients living in urban territory. Environmental pollution (Barking, Essex : 1987), 2018, Volume: 235 Topics: Adult; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Cities; Dust; Environmental Exposure;	2018
Transfer coefficients better reflect emphysematous changes than carbon monoxide diffusing capacity in obstructive lung diseases. Journal of applied physiology (Bethesda, Md. : 1985), 2018, 07-01, Volume: 125, Issue:1 Topics: Asthma; Carbon Monoxide; Female; Forced Expiratory Volume; Humans; Lung; Male; Middle Aged; Pulmonar	2018
Asthma-COPD Overlap Phenotypes and Smoking :Comparative features of asthma in smoking or non-smoking patients with an incomplete reversibility of airway obstruction. COPD, 2018, Volume: 15, Issue:2 Topics: Aged; Asthma; Carbon Monoxide; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Non-Smoke	2018
Influence of Air Pollution on Hospital Admissions in Adult Asthma in Northeast China. Chinese medical journal, 2018, May-05, Volume: 131, Issue:9 Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; China; Environmental Monitoring; Female; Hos	2018
Air pollution exposure during pregnancy: maternal asthma and neonatal respiratory outcomes. Annals of epidemiology, 2018, Volume: 28, Issue:9 Topics: Air Pollutants; Air Pollution; Asphyxia; Asphyxia Neonatorum; Asthma; Carbon Monoxide; Environmental	2018
Association between exhaled carbon monoxide and asthma outcomes in Peruvian children. Respiratory medicine, 2018, Volume: 145 Topics: Adolescent; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Child; Female; Health Resources; Huma	2018
Influence of Mouth Pressure on Measurement of Diffusing Capacity in the Clinical Pulmonary Function Laboratory. Respiratory care, 2019, Volume: 64, Issue:5 Topics: Adult; Aged; Asthma; Breath Holding; Carbon Monoxide; Dyspnea; Female; Forced Expiratory Volume; Hum	2019
Longitudinal trends in asthma emergency department visits, pollutant and pollen levels, and weather variables in the Bronx from 2001-2008. The Journal of asthma : official journal of the Association for the Care of Asthma, 2020, Volume: 57, Issue:5 Topics: Adult; Air Pollutants; Asthma; Carbon Monoxide; Child; Emergency Service, Hospital; Environmental Mo	2020
Dose-dependent relationship between prenatal exposure to fine particulates and exhaled carbon monoxide in non-asthmatic children. A population-based birth cohort study. International journal of occupational medicine and environmental health, 2013, Volume: 26, Issue:1 Topics: Asthma; Carbon Monoxide; Child; Environmental Exposure; Exhalation; Female; Follow-Up Studies; Human	2013
Association of allergic rhinitis or asthma with pollen and chemical pollutants in Szeged, Hungary, 1999-2007. International journal of biometeorology, 2014, Volume: 58, Issue:5 Topics: Adolescent; Adult; Aged; Air Pollutants; Allergens; Ambrosia; Asthma; Carbon Monoxide; Environmental	2014
The etymological role of the main atmosphere pollutants in development of human diseases. Georgian medical news, 2013, Issue:217 Topics: Air Pollutants; Asthma; Bronchitis; Carbon Monoxide; Dust; Environmental Monitoring; Humans; Longitu	2013
Asthma morbidity and ambient air pollution: effect modification by residential traffic-related air pollution. Epidemiology (Cambridge, Mass.), 2014, Volume: 25, Issue:1 Topics: Adolescent; Air Pollution; Asthma; California; Carbon Monoxide; Child; Child, Preschool; Effect Modi	2014
The relationships between ambient air pollutants and childhood asthma and eczema are modified by emotion and conduct problems. Annals of epidemiology, 2013, Volume: 23, Issue:12 Topics: Air Pollutants; Asthma; Benzene; Carbon Monoxide; Child; Child Behavior; Child Behavior Disorders; C	2013
Increased ultrafine particles and carbon monoxide concentrations are associated with asthma exacerbation among urban children. Environmental research, 2014, Volume: 129 Topics: Adrenal Cortex Hormones; Air Pollutants; Asthma; Carbon Monoxide; Child; Child, Preschool; Disease P	2014
Classification and regression trees for epidemiologic research: an air pollution example. Environmental health : a global access science source, 2014, Mar-13, Volume: 13, Issue:1 Topics: Adolescent; Air Pollutants; Air Pollution; Algorithms; Asthma; Carbon Monoxide; Child; Child, Presch	2014
Factors influencing the levels of exhaled carbon monoxide in asthmatic children. The Journal of asthma : official journal of the Association for the Care of Asthma, 2014, Volume: 51, Issue:9 Topics: Adolescent; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Child; Eosinophils; Exhalation; Femal	2014
Effects of sex hormones on bronchial reactivity during the menstrual cycle. BMC pulmonary medicine, 2014, Jul-01, Volume: 14 Topics: Adult; Asthma; Bronchial Provocation Tests; Carbon Monoxide; Cyclic AMP; Estradiol; Female; Follicle	2014
Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality. International journal of chronic obstructive pulmonary disease, 2014, Volume: 9 Topics: Adolescent; Adult; Aged; Air Pollutants; Asthma; Carbon Monoxide; Environmental Monitoring; Female;	2014
Assessment of lung function in asthma and COPD using hyperpolarized 129Xe chemical shift saturation recovery spectroscopy and dissolved-phase MRI. NMR in biomedicine, 2014, Volume: 27, Issue:12 Topics: Adolescent; Adult; Asthma; Carbon Monoxide; Computer Simulation; Erythrocytes; Female; Humans; Imagi	2014
Occupational exposures, smoking and airway inflammation in refractory asthma. BMC pulmonary medicine, 2014, Dec-19, Volume: 14 Topics: Aged; Asthma; Asthma, Occupational; Australia; Breath Tests; Carbon Monoxide; Cell Count; Female; Hu	2014
Fractional exhaled nitric oxide (FeNO) among office workers in an academic institution, Malaysia--associations with asthma, allergies and office environment. The Journal of asthma : official journal of the Association for the Care of Asthma, 2016, Volume: 53, Issue:2 Topics: Adult; Air Pollutants; Air Pollution, Indoor; Allergens; Asthma; Body Height; Body Mass Index; Breat	2016
Allergens, air pollutants, and childhood allergic diseases. International journal of hygiene and environmental health, 2016, Volume: 219, Issue:1 Topics: Air Pollutants; Air Pollution; Allergens; Animals; Asthma; Carbon Monoxide; Child; Child, Preschool;	2016
Coarse Particulate Air Pollution Associated with Increased Risk of Hospital Admissions for Respiratory Diseases in a Tropical City, Kaohsiung, Taiwan. International journal of environmental research and public health, 2015, Oct-16, Volume: 12, Issue:10 Topics: Air Pollution; Asthma; Carbon Monoxide; Cities; Cross-Over Studies; Hospitalization; Humans; Lung Di	2015
The effect of Asian dust on asthma by socioeconomic status using national health insurance claims data in Korea. Inhalation toxicology, 2016, Volume: 28, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Air Pollutants; Asia; Asthma; Carbon Monoxide; Child; Da	2016
Perinatal air pollution exposure and development of asthma from birth to age 10 years. The European respiratory journal, 2016, Volume: 47, Issue:4 Topics: Air Pollutants; Air Pollution; Asthma; British Columbia; Carbon Monoxide; Case-Control Studies; Chil	2016
Air pollution exposure and preeclampsia among US women with and without asthma. Environmental research, 2016, Volume: 148 Topics: Adult; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Female; Humans; Nitrogen Oxides; Part	2016
Air pollution and asthma attacks in children: A case-crossover analysis in the city of Chongqing, China. Environmental pollution (Barking, Essex : 1987), 2017, Volume: 220, Issue:Pt A Topics: Adolescent; Air Pollutants; Air Pollution; Animals; Asthma; Carbon Monoxide; Child; China; Female; H	2017
Impact of Air Pollutants on Outpatient Visits for Acute Respiratory Outcomes. International journal of environmental research and public health, 2017, 01-05, Volume: 14, Issue:1 Topics: Acute Disease; Air Pollutants; Air Pollution; Ambulatory Care; Asthma; Bronchitis; Carbon Monoxide;	2017
The INDEX project: executive summary of a European Union project on indoor air pollutants. Allergy, 2008, Volume: 63, Issue:7 Topics: Air Pollutants; Air Pollution, Indoor; Asthma; Benzene; Carbon Monoxide; Europe; European Union; For	2008
Exhaled carbon monoxide levels: as a marker of clinical severity and control of asthma. The Journal of asthma : official journal of the Association for the Care of Asthma, 2008, Volume: 45, Issue:8 Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Asthma; Budesonide; Carbon Monoxide; Et	2008
Loose-coupling an air dispersion model and a geographic information system (GIS) for studying air pollution and asthma in the Bronx, New York City. International journal of environmental health research, 2009, Volume: 19, Issue:1 Topics: Air Movements; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Environmental Exposure; Geogr	2009
[Air pollution and recent symptoms of asthma, allergic rhinitis, and atopic eczema in schoolchildren aged between 6 and 7 years]. Archivos de bronconeumologia, 2009, Volume: 45, Issue:5 Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child; Cough; Dermatitis, Atopic; Female; Hu	2009
Prevalence of active and passive smoking in a population of patients with asthma. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2009, Volume: 35, Issue:3 Topics: Adult; Asthma; Brazil; Carbon Monoxide; Exhalation; Female; Humans; Male; Prevalence; Severity of Il	2009
Carbon monoxide pollution is associated with decreased lung function in asthmatic adults. The European respiratory journal, 2010, Volume: 35, Issue:2 Topics: Adult; Air Pollutants; Asthma; Carbon Monoxide; Environmental Monitoring; Europe; Forced Expiratory	2010
Exhaled carbon monoxide in asthmatic adults with bronchial reactivity: a prospective study. The Journal of asthma : official journal of the Association for the Care of Asthma, 2009, Volume: 46, Issue:7 Topics: Adult; Asthma; Biomarkers; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bro	2009
The influence of traffic-related pollution on individuals' life-style: results from the BRFSS. Health economics, 2010, Volume: 19, Issue:11 Topics: Age Factors; Air Pollutants; Air Pollution; Asthma; Behavioral Risk Factor Surveillance System; Carb	2010
Long-term exposure to close-proximity air pollution and asthma and allergies in urban children. The European respiratory journal, 2010, Volume: 36, Issue:1 Topics: Air Pollution; Asthma; Benzene; Carbon Monoxide; Child; Cross-Sectional Studies; Environmental Expos	2010
Effect of early life exposure to air pollution on development of childhood asthma. Environmental health perspectives, 2010, Volume: 118, Issue:2 Topics: Air Pollution; Asthma; British Columbia; Carbon Monoxide; Case-Control Studies; Child, Preschool; En	2010
Traffic marker?: early exposure to air pollution associated with childhood asthma. Environmental health perspectives, 2010, Volume: 118, Issue:2 Topics: Air Pollution; Asthma; Carbon Monoxide; Child, Preschool; Environmental Exposure; Female; Humans; Ma	2010
Factors attributable to the level of exhaled nitric oxide in asthmatic children. European journal of medical research, 2009, Dec-07, Volume: 14 Suppl 4 Topics: Adult; Asthma; Breath Tests; Carbon Monoxide; Female; Humans; Immunoglobulin E; Male; Middle Aged; N	2009
Hospital admissions for respiratory conditions in children and outdoor air pollution in Southwest Milan, Italy. Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:8 Topics: Adolescent; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child; Environmental Monitoring;	2010
[About interpretation of exhaled CO in smoking cessation]. Revue des maladies respiratoires, 2010, Volume: 27, Issue:4 Topics: Asthma; Bronchiectasis; Carbon Monoxide; Carboxyhemoglobin; Exhalation; Female; Humans; Male; Pulmon	2010
Bronchoprovocation testing in asthma: effect on exhaled monoxides. Journal of breath research, 2010, Volume: 4, Issue:4 Topics: Adult; Allergens; Asthma; Breath Tests; Bronchial Provocation Tests; Bronchoconstrictor Agents; Carb	2010
The association of seasonal variations of asthma hospitalization with air pollution among children in Taiwan. Asian Pacific journal of allergy and immunology, 2011, Volume: 29, Issue:1 Topics: Adolescent; Age Factors; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child; Child, Presc	2011
Fluctuation analysis-based risk assessment for respiratory virus activity and air pollution associated asthma incidence. The Science of the total environment, 2011, Aug-15, Volume: 409, Issue:18 Topics: Air Microbiology; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Environmental Monitoring;	2011
Clinical study of multiple breath biomarkers of asthma and COPD (NO, CO(2), CO and N(2)O) by infrared laser spectroscopy. Journal of breath research, 2011, Volume: 5, Issue:3 Topics: Adolescent; Adult; Asthma; Breath Tests; Carbon Monoxide; Child; Exhalation; Female; Humans; Male; N	2011
Seven-days-ahead forecasting of childhood asthma admissions using artificial neural networks in Athens, Greece. International journal of environmental health research, 2012, Volume: 22, Issue:2 Topics: Adolescent; Air Pollutants; Asthma; Carbon Monoxide; Child; Child, Preschool; Female; Forecasting; G	2012
Association of ozone exposure with asthma, allergic rhinitis, and allergic sensitization. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2011, Volume: 107, Issue:3 Topics: Air Pollutants; Asthma; Carbon Monoxide; Child; Environmental Exposure; Female; Health Surveys; Huma	2011
Exhaled carbon monoxide levels in preschool-age children with episodic asthma. Pediatrics international : official journal of the Japan Pediatric Society, 2012, Volume: 54, Issue:2 Topics: Albuterol; Asthma; Breath Tests; Bronchodilator Agents; Carbon Monoxide; Cromolyn Sodium; Drug Thera	2012
An analysis of asthma hospitalizations, air pollution, and weather conditions in Los Angeles County, California. The Science of the total environment, 2012, May-15, Volume: 425 Topics: Air Pollution; Asthma; Bayes Theorem; California; Carbon Monoxide; Environmental Monitoring; Epidemi	2012
Forecasting peak asthma admissions in London: an application of quantile regression models. International journal of biometeorology, 2013, Volume: 57, Issue:4 Topics: Air Pollutants; Asthma; Carbon Monoxide; Forecasting; Formaldehyde; Hospitalization; Humans; London;	2013
Exhaled carbon monoxide is not elevated in patients with asthma or cystic fibrosis. The European respiratory journal, 2002, Volume: 20, Issue:1 Topics: Adolescent; Adult; Asthma; Breath Tests; Bronchodilator Agents; Carbon Monoxide; Chemical Fractionat	2002
Effect of short-term exposure to gaseous pollution on asthma hospitalisation in children: a bi-directional case-crossover analysis. Journal of epidemiology and community health, 2003, Volume: 57, Issue:1 Topics: Air Pollutants; Asthma; Carbon Monoxide; Child; Cross-Over Studies; Environmental Exposure; Female;	2003
An assessment of the role of exhaled carbon monoxide in acute asthmatic exacerbations in hospitalised patients. Singapore medical journal, 2002, Volume: 43, Issue:8 Topics: Acute Disease; Adrenal Cortex Hormones; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Hospitali	2002
The effects of air pollution on acute respiratory conditions. Respirology (Carlton, Vic.), 2003, Volume: 8, Issue:2 Topics: Adult; Aged; Air Pollutants; Analysis of Variance; Asthma; Carbon Monoxide; Emergency Service, Hospi	2003
The 3-year follow-up study in a block of flats - experiences in the use of the Finnish indoor climate classification. Indoor air, 2003, Volume: 13, Issue:2 Topics: Air Pollution, Indoor; Allergens; Ammonia; Asthma; Bacteria; Carbon Dioxide; Carbon Monoxide; Constr	2003
Clarithromycin and pulmonary infiltration with eosinophilia. BMJ (Clinical research ed.), 2003, Jun-21, Volume: 326, Issue:7403 Topics: Adolescent; Anti-Bacterial Agents; Asthma; Carbon Monoxide; Cerebrospinal Fluid Rhinorrhea; Clarithr	2003
[Pulmonary diffusion capacity for carbon monoxide studied with the rebreathing method. II. Results in patients with chronic bronchitis, bronchial asthma and pulmonary emphysema]. Giornale di clinica medica, 1961, Volume: 42 Topics: Asthma; Bronchitis; Bronchitis, Chronic; Carbon Monoxide; Humans; Lung; Pulmonary Diffusing Capacity	1961
MEASUREMENT OF THE LUNG DIFFUSING CAPACITY FOR CARBON MONOXIDE AND OF NON-UNIFORM VENTILATION BY MEANS OF A CLOSED SYSTEM. Scandinavian journal of clinical and laboratory investigation, 1963, Volume: 15 Topics: Asthma; Bronchitis; Carbon Monoxide; Humans; Pulmonary Emphysema; Respiratory Function Tests; Spirom	1963
[THE DIFFUSION CAPACITY OF THE LUNGS FOR CARBON MONOXIDE DETERMINED WITH THE AID OF ARTERIAL AND ALVEOLAR CARBON DIOXIDE PRESSURE IN PATIENTS WITH VENTILATION DISORDERS]. Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1963, Volume: 277 Topics: Asthma; Carbon Dioxide; Carbon Monoxide; Humans; Lung; Pulmonary Emphysema; Respiration Disorders; R	1963
AN ASSESSMENT OF THE FRACTIONAL CARBON MONOXIDE UPTAKE AND ITS RELATIONSHIP TO PULMONARY DIFFUSING CAPACITY. Diseases of the chest, 1964, Volume: 46 Topics: Asthma; Carbon Monoxide; Emphysema; Humans; Hyperventilation; Lung Diseases; Physical Exertion; Pulm	1964
[STUDY OF RESPIRATORY DISORDERS IN PNEUMOCONIOSIS PATIENTS BY MEASURING THE ALVEOLO-CAPILLARY DIFFUSION OF CARBON MONOXIDE]. Medicina thoracalis, 1964, Volume: 21 Topics: Asthma; Capillaries; Carbon Monoxide; Diagnosis, Differential; Humans; Pneumoconiosis; Pulmonary Alv	1964
Optimal cutoff level of breath carbon monoxide for assessing smoking status in patients with asthma and COPD. Chest, 2003, Volume: 124, Issue:5 Topics: Adolescent; Adult; Aged; Asthma; Breath Tests; Carbon Monoxide; Cotinine; Cross-Sectional Studies; F	2003
Exhaled gas analysis and airway inflammation. Pediatric pulmonology. Supplement, 2004, Volume: 26 Topics: Acetates; Asthma; Breath Tests; Carbon Monoxide; Cyclopropanes; Glucocorticoids; Humans; Leukotriene	2004
Relationship between exhaled carbon monoxide and airway hyperresponsiveness in asthmatic patients. The Journal of asthma : official journal of the Association for the Care of Asthma, 2004, Volume: 41, Issue:1 Topics: Adult; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbon Monoxide	2004
Childhood asthma: exhaled markers of airway inflammation, asthma control score, and lung function tests. Pediatric pulmonology, 2004, Volume: 38, Issue:2 Topics: Adolescent; Albumins; Asthma; Breath Tests; C-Reactive Protein; Carbon Monoxide; Case-Control Studie	2004
Exhaled carbon monoxide is not flow dependent in children with cystic fibrosis and asthma. European journal of medical research, 2004, Nov-29, Volume: 9, Issue:11 Topics: Adolescent; Age Factors; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Child; Cystic Fibrosis;	2004
Predictors of success in smoking cessation among hospitalized patients. Respirology (Carlton, Vic.), 2005, Volume: 10, Issue:1 Topics: Age of Onset; Asthma; Attitude to Health; Breath Tests; Carbon Monoxide; Cohort Studies; Counseling;	2005
Does socio-demographic status influence the effect of pollens and molds on hospitalization for asthma? Results from a time-series study in 10 Canadian cities. Annals of epidemiology, 2005, Volume: 15, Issue:3 Topics: Adolescent; Adult; Aged; Air Pollutants; Allergens; Asthma; Atmospheric Pressure; Basidiomycota; Can	2005
[Effect of passive cigarette smoking on the frequency of respiratory tract infections, allergy and bronchial asthma in children]. Przeglad lekarski, 2004, Volume: 61, Issue:10 Topics: Adolescent; Asthma; Carbon Monoxide; Case-Control Studies; Child; Child, Preschool; Female; Humans;	2004
The relationship of air pollution to the prevalence of allergic diseases in Taichung and Chu-Shan in 2002. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2005, Volume: 38, Issue:2 Topics: Adolescent; Air Pollution; Asthma; Carbon Monoxide; Child; Dermatitis, Atopic; Female; Humans; Hyper	2005
Traffic related air pollution as a determinant of asthma among Taiwanese school children. Thorax, 2005, Volume: 60, Issue:6 Topics: Adolescent; Air Pollutants; Asthma; Carbon Monoxide; Child; Cross-Sectional Studies; Female; Humans;	2005
Short and long-term effects of cigarette smoking independently influence exhaled nitric oxide concentration in asthma. The Journal of allergy and clinical immunology, 2005, Volume: 116, Issue:1 Topics: Adult; Asthma; Breath Tests; Carbon Monoxide; Cross-Sectional Studies; Female; Humans; Male; Middle	2005
Effects of ambient particulate matter on peak expiratory flow rates and respiratory symptoms of asthmatics during Asian dust periods in Korea. Respirology (Carlton, Vic.), 2005, Volume: 10, Issue:4 Topics: Adult; Air Pollutants; Asthma; Carbon Monoxide; Dust; Environmental Monitoring; Female; Humans; Kore	2005
Expression of heme oxygenase-1 in the peripheral blood mononuclear cells from asthmatic patients. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:4 Topics: Adult; Asthma; Carbon Monoxide; Female; Heme Oxygenase-1; Humans; Immunoglobulin E; Leukocytes, Mono	2005
An analysis of effects of San Diego wildfire on ambient air quality. Journal of the Air & Waste Management Association (1995), 2006, Volume: 56, Issue:1 Topics: Air Pollutants; Asthma; California; Carbon Monoxide; Cities; Dust; Emergency Service, Hospital; Envi	2006
The relationship between changes in daily air pollution and hospitalizations in Perth, Australia 1992-1998: a case-crossover study. International journal of environmental health research, 2006, Volume: 16, Issue:1 Topics: Air Pollution; Asthma; Carbon Monoxide; Cardiovascular Diseases; Cities; Cross-Sectional Studies; En	2006
Exhaled carbon monoxide levels in school-age children with episodic asthma. Pediatric pulmonology, 2006, Volume: 41, Issue:5 Topics: Acute Disease; Albuterol; Anti-Asthmatic Agents; Asthma; Breath Tests; Bronchodilator Agents; Carbon	2006
Air pollution and hospital admissions for asthma in a tropical city: Kaohsiung, Taiwan. Inhalation toxicology, 2006, Volume: 18, Issue:8 Topics: Air Pollutants; Asthma; Carbon Monoxide; Environmental Monitoring; Epidemiological Monitoring; Hospi	2006
Bias and confounding in longitudinal measures of exhaled monoxides. Journal of exposure science & environmental epidemiology, 2007, Volume: 17, Issue:6 Topics: Adolescent; Adult; Air Pollutants; Air Pollution, Indoor; Asthma; Bias; Breath Tests; Carbon Monoxid	2007
Prevalence of symptoms of asthma, rhinitis, and atopic eczema in Brazilian adolescents related to exposure to gaseous air pollutants and socioeconomic status. Journal of investigational allergology & clinical immunology, 2007, Volume: 17, Issue:1 Topics: Adolescent; Air Pollutants; Asthma; Brazil; Carbon Monoxide; Dermatitis, Atopic; Humans; Nitrogen Di	2007
Air pollution and hospital admissions for asthma in a subtropical city: Taipei, Taiwan. Journal of toxicology and environmental health. Part A, 2007, Jan-15, Volume: 70, Issue:2 Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Cities; Environmental Monitoring; Epidemiolo	2007
The effect of sandstorms and air pollution on cause-specific hospital admissions in Taipei, Taiwan. Occupational and environmental medicine, 2008, Volume: 65, Issue:2 Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Cerebrovascular Disorders; Environmental Exp	2008
Ambient air pollution triggers wheezing symptoms in infants. Thorax, 2008, Volume: 63, Issue:8 Topics: Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child, Preschool; Denmark; Epidemiologic Met	2008
Transfer factor for carbon monoxide in patients with airways obstruction. Clinical science, 1967, Volume: 32, Issue:2 Topics: Adult; Asthma; Bronchitis; Carbon Monoxide; Humans; Physical Exertion; Pulmonary Emphysema; Respirat	1967
An analog computer analysis of regional diffusing capacity in airflow obstruction. Journal of applied physiology, 1967, Volume: 22, Issue:6 Topics: Acetylene; Adult; Aged; Asthma; Carbon Monoxide; Computers, Analog; Female; Humans; Lung; Male; Midd	1967
[Health disorders caused by air pollutants]. Acta medica Austriaca, 1984, Volume: 11, Issue:5 Topics: Air Pollutants; Asthma; Bronchitis; Carbon Monoxide; Carcinoma, Bronchogenic; Humans; Lung Neoplasms	1984
Overestimation of the single-breath carbon monoxide diffusing capacity in patients with air-flow obstruction. The American review of respiratory disease, 1984, Volume: 129, Issue:3 Topics: Adolescent; Adult; Asthma; Carbon Monoxide; Cystic Fibrosis; Emphysema; Female; Humans; Lung Disease	1984
Factors affecting expired waveform for carbon monoxide. Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 56, Issue:3 Topics: Adult; Analysis of Variance; Asthma; Carbon Monoxide; Female; Functional Residual Capacity; Humans;	1984
Dynamic measurements of CO diffusing capacity using discrete samples of alveolar gas. Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 54, Issue:1 Topics: Adult; Aged; Asthma; Carbon Monoxide; Emphysema; Female; Humans; Male; Middle Aged; Physiology; Pulm	1983
Single breath diffusing capacity for carbon monoxide in stable asthma. Chest, 1994, Volume: 105, Issue:5 Topics: Adult; Aged; Asthma; Carbon Monoxide; Female; Forced Expiratory Volume; Humans; Lung; Male; Middle A	1994
The decrease in severity of asthma in children of parents who smoke since the parents have been exposing them to less cigarette smoke. The Journal of allergy and clinical immunology, 1993, Volume: 91, Issue:1 Pt 1 Topics: Adolescent; Adult; Analysis of Variance; Asthma; Breath Tests; British Columbia; Bronchial Provocati	1993
Particulate air pollution and respiratory disease in Anchorage, Alaska. Environmental health perspectives, 1996, Volume: 104, Issue:3 Topics: Air Pollutants; Alaska; Ambulatory Care; Asthma; Bronchitis; Carbon Monoxide; Humans; Respiratory Tr	1996
[Urban atmospheric pollution and human public health]. Allergie et immunologie, 1997, Volume: 29, Issue:6 Topics: Air Pollutants; Animals; Asthma; Carbon Monoxide; Child; France; Hospitalization; Humans; Nitrogen O	1997
The diversity of the effects of sulfur mustard gas inhalation on respiratory system 10 years after a single, heavy exposure: analysis of 197 cases. Chest, 1997, Volume: 112, Issue:3 Topics: Adult; Aged; Airway Obstruction; Asthma; Biopsy; Bronchiectasis; Bronchitis; Bronchoscopy; Carbon Mo	1997
Increased carbon monoxide in exhaled air of asthmatic patients. American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:4 Pt 1 Topics: Administration, Inhalation; Adult; Asthma; Carbon Monoxide; Eosinophils; Female; Glucocorticoids; Hu	1997
Respiratory symptoms in a susceptible population due to burning of agricultural residue. Chest, 1998, Volume: 113, Issue:2 Topics: Adult; Agriculture; Air Pollutants; Air Pollution; Airway Obstruction; Asthma; Bronchial Hyperreacti	1998
Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress. Thorax, 1998, Volume: 53, Issue:8 Topics: Adult; Asthma; Bilirubin; Biomarkers; Breath Tests; Carbon Monoxide; Female; Heme Oxygenase (Decycli	1998
Applicability of the single-breath carbon monoxide diffusing capacity in a Norwegian Community Study. American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:6 Topics: Adolescent; Adult; Age Factors; Aged; Asthma; Carbon Monoxide; Cross-Sectional Studies; Educational	1998
Effects of ambient air pollution on nonelderly asthma hospital admissions in Seattle, Washington, 1987-1994. Epidemiology (Cambridge, Mass.), 1999, Volume: 10, Issue:1 Topics: Adult; Air Pollutants; Air Pollution; Asthma; Carbon Monoxide; Child; Humans; Models, Statistical; P	1999
[Epidemiology of bronchial asthma in a large industrial region]. Terapevticheskii arkhiv, 1998, Volume: 70, Issue:12 Topics: Adolescent; Adult; Age Factors; Air Pollutants; Asthma; Bronchial Hyperreactivity; Carbon Monoxide;	1998
[Pulmonary gas transfer in pediatrics (carbon monoxide and dioxide)]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1998, Volume: 5, Issue:2 Topics: Adolescent; Adult; Asthma; Carbon Dioxide; Carbon Monoxide; Child; Child, Preschool; Exercise Test;	1998
Exhaled carbon monoxide levels during treatment of acute asthma. The European respiratory journal, 1999, Volume: 13, Issue:4 Topics: Administration, Inhalation; Administration, Oral; Anti-Asthmatic Agents; Asthma; Breath Tests; Carbo	1999
Association of air pollution with daily GP consultations for asthma and other lower respiratory conditions in London. Thorax, 1999, Volume: 54, Issue:7 Topics: Adolescent; Adult; Aged; Air Pollution; Asthma; Carbon Monoxide; Child; Child, Preschool; Databases,	1999
Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis. The American journal of medicine, 1999, Volume: 106, Issue:6 Topics: Adult; Asthma; Bronchitis; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Case-Control Studies; Chem	1999
Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:1 Topics: Adult; Airway Resistance; Asthma; Breath Tests; Bronchi; Carbon Monoxide; Dinoprost; F2-Isoprostanes	1999
Emissions testing for children, chapter 2: carbon monoxide. The Journal of pediatrics, 1999, Volume: 135, Issue:5 Topics: Asthma; Breath Tests; Carbon Monoxide; Child; Humans; Nitric Oxide	1999
Exhaled carbon monoxide in childhood asthma. The Journal of pediatrics, 1999, Volume: 135, Issue:5 Topics: Asthma; Breath Tests; Bronchial Provocation Tests; Carbon Monoxide; Child; Cross-Sectional Studies;	1999
Asthma aggravation, combustion, and stagnant air. Thorax, 2000, Volume: 55, Issue:6 Topics: Air Pollutants; Asthma; Carbon Monoxide; Emergency Medical Services; Environmental Exposure; Humans;	2000
Changes in exhaled carbon monoxide and nitric oxide levels following allergen challenge in patients with asthma. The European respiratory journal, 1999, Volume: 13, Issue:1 Topics: Adult; Allergens; Asthma; Carbon Monoxide; Female; Humans; Male; Nitric Oxide; Respiration	1999
Expression of heme oxygenase isoenzymes 1 and 2 in normal and asthmatic airways: effect of inhaled corticosteroids. American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:5 Topics: Administration, Inhalation; Asthma; Blotting, Western; Bronchi; Bronchodilator Agents; Bronchoscopy;	2000
Exhaled carbon monoxide in asthma. The Journal of pediatrics, 2000, Volume: 137, Issue:6 Topics: Asthma; Breath Tests; Carbon Monoxide; Humans; Respiration	2000
Effects of ambient air pollution on symptoms of asthma in Seattle-area children enrolled in the CAMP study. Environmental health perspectives, 2000, Volume: 108, Issue:12 Topics: Adolescent; Air Pollutants; Asthma; Carbon Monoxide; Child; Child Welfare; Child, Preschool; Cohort	2000
Relation between exhaled carbon monoxide levels and clinical severity of asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2001, Volume: 31, Issue:3 Topics: Adult; Aged; Asthma; Biomarkers; Carbon Monoxide; Female; Humans; Male; Middle Aged; Prognosis	2001
Carbon monoxide attenuates aeroallergen-induced inflammation in mice. American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:1 Topics: Allergens; Animals; Asthma; Blood Cells; Bone Marrow; Bronchoalveolar Lavage Fluid; Carbon Monoxide;	2001
[Pulmonary diffusion of carbon monoxide in 2 clinical situations: bronchial asthma and diabetes mellitus]. Anales de medicina interna (Madrid, Spain : 1984), 2001, Volume: 18, Issue:5 Topics: Aged; Asthma; Carbon Monoxide; Diabetes Mellitus; Diffusion; Female; Humans; Lung; Male; Middle Aged	2001
[Detection of exhaled CO as a simple non-invasive tool for monitoring acute exacerbations of asthma in the elderly]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001, Volume: 38, Issue:4 Topics: Aged; Asthma; Breath Tests; Carbon Monoxide; Humans; Peak Expiratory Flow Rate; Respiratory Function	2001
Alterations in exhaled gas profile during allergen-induced asthmatic response. American journal of respiratory and critical care medicine, 2001, Nov-15, Volume: 164, Issue:10 Pt 1 Topics: Adult; Allergens; Asthma; Breath Tests; Bronchial Provocation Tests; Carbon Dioxide; Carbon Monoxide	2001
[Evidence of increased endogenous carbon monoxide production in asthma]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1999, Volume: 22, Issue:4 Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Cell Line; Child; Child, Preschool;	1999
[The expression and regulation of heme oxygenase-1 in asthmatic guinea pigs]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1999, Volume: 22, Issue:10 Topics: Animals; Asthma; Carbon Monoxide; Cyclic GMP; Disease Models, Animal; Gene Expression Regulation, En	1999
Evaluation of the single-breath diffusing capacity in asthma and cystic fibrosis. Chest, 1979, Volume: 76, Issue:1 Topics: Adolescent; Adult; Airway Obstruction; Asthma; Bronchodilator Agents; Carbon Monoxide; Child; Cystic	1979
[Propagation of error, sensitivity and specificity of the CO gas transfer in various breath holding and steady state methods (author's transl)]. Praxis und Klinik der Pneumologie, 1979, Volume: 33 Suppl 1 Topics: Asthma; Carbon Monoxide; Humans; Lung Diseases, Obstructive; Pulmonary Diffusing Capacity	1979
Dco at various breath-holding times: comparison in patients with chronic bronchial asthma and emphysema. Respiration; international review of thoracic diseases, 1979, Volume: 37, Issue:4 Topics: Adult; Asthma; Carbon Monoxide; Chronic Disease; Humans; Lung; Middle Aged; Pulmonary Diffusing Capa	1979
The role of air pollution and weather changes in childhood asthma. Annals of allergy, 1977, Volume: 39, Issue:6 Topics: Adolescent; Air Pollution; Asthma; Carbon Monoxide; Child; Humans; Ozone; Pollen; Regression Analysi	1977
[Carbon monoxide levels in asthamtic patients of Mexico City]. Alergia, 1977, Volume: 24, Issue:2 Topics: Adolescent; Adult; Air Pollutants; Asthma; Carbon Monoxide; Carboxyhemoglobin; Female; Hemoglobins;	1977
Pulmonary diffusing capacity measured at multiple intervals during a single exhalation in man. Journal of applied physiology: respiratory, environmental and exercise physiology, 1977, Volume: 43, Issue:4 Topics: Adult; Asthma; Blood Volume; Carbon Monoxide; Chronic Disease; Humans; Lung Diseases, Obstructive; M	1977
A multifactorial study of patients with asthma. Part 2: air pollution, animal dander and asthma symptoms. Annals of allergy, 1976, Volume: 37, Issue:6 Topics: Adolescent; Adult; Aged; Air Pollution; Allergens; Asthma; Carbon Monoxide; Child; Environmental Exp	1976
Clinical relevance of the flow rate response to low density gas breathing in asthmatics. The American review of respiratory disease, 1975, Volume: 111, Issue:2 Topics: Acute Disease; Adolescent; Adult; Aged; Airway Obstruction; Asthma; Bronchodilator Agents; Carbon Mo	1975
The spirographic "kink". A sign of emphysema. Chest, 1976, Volume: 69, Issue:1 Topics: Asthma; Carbon Monoxide; Emphysema; False Positive Reactions; Female; Forced Expiratory Flow Rates;	1976
[Pulmonary transfer factor for carbon monoxide (TLco) in healthy children and in children with chronic lung diseases, measured with an improved rebreathing technique]. Pneumologie (Stuttgart, Germany), 1990, Volume: 44, Issue:10 Topics: Asthma; Carbon Monoxide; Child; Cystic Fibrosis; Humans; Pulmonary Diffusing Capacity; Respiratory F	1990
[Laboratory diagnostic monitoring of blood gas parameters in children during bronchologic studies]. Zeitschrift fur Erkrankungen der Atmungsorgane, 1990, Volume: 174, Issue:2 Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Anesthesia, General; Anesthesia, Inhalation; Asthma; B	1990
Single breath carbon monoxide transfer factor in different forms of chronic airflow obstruction in a general population sample. Thorax, 1990, Volume: 45, Issue:7 Topics: Adult; Aged; Asthma; Carbon Monoxide; Epidemiologic Methods; Female; Humans; Lung; Lung Diseases, Ob	1990
Carbon monoxide diffusing capacity in asthmatic patients with mild airflow limitation. Chest, 1988, Volume: 94, Issue:2 Topics: Adult; Asthma; Carbon Monoxide; Humans; Lung; Lung Volume Measurements; Pulmonary Diffusing Capacity	1988
A longitudinal study of symptoms and respiratory function tests in iron miners. European journal of respiratory diseases, 1986, Volume: 69, Issue:5 Topics: Adult; Asthma; Bronchitis; Carbon Monoxide; Chronic Disease; France; Health; Health Status; Humans;	1986
Carbon monoxide levels in cardiac patients in an urban emergency department. The American journal of emergency medicine, 1986, Volume: 4, Issue:2 Topics: Asthma; Carbon Monoxide; Carboxyhemoglobin; Coronary Disease; Heart Diseases; Heart Failure; Hemoglo	1986
[Exacerbation of bronchial asthma as an indicator of air pollution]. Gigiena i sanitariia, 1985, Issue:1 Topics: Acute Disease; Air Pollutants; Asthma; Carbon Monoxide; Humans; Hydrocarbons	1985
Effect of breath-hold time on DLCO(SB) in patients with airway obstruction. Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:4 Topics: Adult; Airway Obstruction; Asthma; Carbon Monoxide; Female; Humans; Male; Middle Aged; Pulmonary Alv	1985
Epidemiology and environmental health policy. International journal of epidemiology, 1972,Summer, Volume: 1, Issue:2 Topics: Air Pollution; Animals; Asthma; Bronchitis; California; Carbon Monoxide; Environmental Health; Epide	1972
[Scandinavian seminar: environmental pollution and heart and lung diseases]. Nordisk medicin, 1974, Volume: 89, Issue:10 Topics: Adult; Air Pollutants; Air Pollution; Asbestos; Asthma; Bronchitis; Carbon Monoxide; Child; Environm	1974
Transfer factor in asthma. Lancet (London, England), 1970, Apr-04, Volume: 1, Issue:7649 Topics: Asthma; Carbon Monoxide; Humans; Pulmonary Alveoli; Respiration; Spirometry	1970
Diffusing capacity and over-all ventilation:perfusion in asthma. The American journal of medicine, 1974, Volume: 57, Issue:5 Topics: Airway Obstruction; Airway Resistance; Asthma; Blood; Carbon Dioxide; Carbon Monoxide; Humans; Hydro	1974
Pulmonary function during clinical remission of asthma. How reversible is asthma? Australian and New Zealand journal of medicine, 1973, Volume: 3, Issue:6 Topics: Adolescent; Adult; Age Factors; Aged; Airway Obstruction; Asthma; Carbon Dioxide; Carbon Monoxide; F	1973
Oxyhemoglobin affinity in bronchial asthma: chronic stable state, acute, and status asthmaticus. Chest, 1972, Volume: 62, Issue:6 Topics: Acute Disease; Adult; Asthma; Carbon Dioxide; Carbon Monoxide; Chronic Disease; Erythrocytes; Female	1972
[Patterns of lung function in moderate chronic bronchitis and allergic asthma]. Pneumonologie. Pneumonology, 1972, Volume: 148, Issue:1 Topics: Adult; Air; Airway Resistance; Asthma; Bronchitis; Carbon Monoxide; Chronic Disease; Humans; Lung; M	1972
The diffusing capacity in asthma. Effect of airflow obstruction. The American review of respiratory disease, 1973, Volume: 107, Issue:6 Topics: Adult; Airway Obstruction; Asthma; Carbon Monoxide; Female; Humans; Male; Middle Aged; Partial Press	1973
Single-breath gas distribution in chronic obstructive lung disease. Isoproterenol effect on neon dilution volume and diffusing capacity. Archives of internal medicine, 1971, Volume: 127, Issue:4 Topics: Adult; Airway Resistance; Asthma; Bronchitis; Carbon Monoxide; Diffusion; Female; Humans; Indicator	1971
Bronchial asthma in children and its occurrence in relation to weather and air pollution. Annals of allergy, 1972, Volume: 30, Issue:5 Topics: Air Pollution; Asthma; Atmospheric Pressure; Carbon Monoxide; Child; Emergency Service, Hospital; Ho	1972
[Pulmonary diffusing capacity and regional pulmonary function]. Iryo, 1971, Volume: 25, Issue:7 Topics: Adolescent; Adult; Aged; Asthma; Carbon Monoxide; Chronic Disease; Female; Heart Septal Defects, Atr	1971
Pulmonary diffusing capacity, membrane diffusing capacity, and capillary blood volume in children with intractable asthma with and without chronic overinflation of the lungs. The Journal of allergy, 1966, Volume: 37, Issue:4 Topics: Adolescent; Asthma; Blood Cells; Blood Volume; Capillaries; Capillary Permeability; Carbon Monoxide;	1966
Comparison of midplane, full-chest tomograms, diffusing capacities, sputum eosinophil content, and other parameters in patients with asthma and emphysema. The Journal of allergy, 1969, Volume: 44, Issue:3 Topics: Adult; Aged; Asthma; Carbon Monoxide; Diagnosis, Differential; Diffusion; Eosinophils; Female; Human	1969
A comparison of pulmonary function in bronchial asthma and chronic obstructive bronchitis. Thorax, 1970, Volume: 25, Issue:1 Topics: Adolescent; Adult; Aged; Asthma; Bronchitis; Carbon Dioxide; Carbon Monoxide; Child; Chronic Disease	1970
[Utility of the diffusion test with carbon monoxide in functional exploration of the lung]. Helvetica medica acta, 1967, Volume: 34, Issue:1 Topics: Age Factors; Asthma; Bronchitis; Carbon Monoxide; Emphysema; Humans; Lung Neoplasms; Pulmonary Fibro	1967
Organization of a hospital routine pulmonary function laboratory. Canadian Medical Association journal, 1968, Mar-16, Volume: 98, Issue:11 Topics: Adolescent; Adult; Aged; Asthma; Blood Gas Analysis; Bronchitis; Carbon Dioxide; Carbon Monoxide; Ch	1968
Pulmonary function in bronchial asthma. British medical journal, 1968, Feb-24, Volume: 1, Issue:5590 Topics: Adult; Asthma; Blood Gas Analysis; Bronchi; Bronchitis; Carbon Dioxide; Carbon Monoxide; Emphysema;	1968
Air quality parameters for epidemiologic studies. Archives of environmental health, 1968, Volume: 16, Issue:2 Topics: Air Pollution; Allergens; Asthma; Cadmium; Carbon Monoxide; Conjunctiva; Digestive System; Epidemiol	1968
[Studies on the measurement of the carbon monoxide diffusing capacity by the single-breath method, with special reference to the influence of the uneven distribution of ventilation-perfusion of the lungs]. Japanese circulation journal, 1968, Volume: 32, Issue:1 Topics: Adult; Asthma; Blood Volume; Carbon Monoxide; Computers; Female; Humans; Lung; Male; Methods; Middle	1968
Effect of acetylcholine aerosols on diffusing capacity in asthmatic and normal subjects. Journal of applied physiology, 1969, Volume: 26, Issue:2 Topics: Acetylcholine; Adult; Aerosols; Apnea; Asthma; Carbon Monoxide; Diffusion; Female; Humans; Male; Mid	1969
Pulmonary diffusing capacity among Japanese patients with clinical features similar to Tokyo-Yokohama asthma. The American review of respiratory disease, 1966, Volume: 94, Issue:5 Topics: Adolescent; Adult; Asian People; Asthma; Carbon Monoxide; Female; Humans; Japan; Male; Pulmonary Emp	1966
[A study on CO diffusing capacity with reference to pulmonary hemodynamics and ventilatory functions in patients with cardiac or chronic pulmonary disease]. Japanese circulation journal, 1966, Volume: 30, Issue:3 Topics: Asthma; Carbon Monoxide; Cardiac Catheterization; Heart Valve Diseases; Humans; Hypertension; Lung N	1966

carbon monoxide and Asthma, Bronchial