Page last updated: 2024-10-16

carbon monoxide and Anxiety Disorders

carbon monoxide has been researched along with Anxiety Disorders in 7 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Anxiety Disorders: Persistent and disabling ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"Results from this study will inform FDA on the potential effects of regulating the nicotine content of cigarettes and help determine whether smokers with mood and/or anxiety disorders can safely transition to significantly reduced nicotine content cigarettes."9.24A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol. ( Allen, SI; Azzouz, N; Cather, C; Evins, AE; Foulds, J; Hameed, A; Hammett, E; Hrabovsky, S; Krebs, NM; Liao, J; Modesto, J; Muscat, JE; Pachas, GN; Richie, J; Veldheer, S; Yingst, J; Zhu, J, 2017)
"In this case report, a 40-year-old male with a past medical history of depression, anxiety, panic attacks, and substance use disorder developed symptomatic, acute carbon monoxide poisoning secondary to heavy cigarette smoking in a confined space."7.91Acute Carbon Monoxide Poisoning Secondary to Cigarette Smoking in a 40-Year-Old Man: A Case Report. ( Aloi, J; Neilsen, BK; Sharma, A, 2019)
"Results from this study will inform FDA on the potential effects of regulating the nicotine content of cigarettes and help determine whether smokers with mood and/or anxiety disorders can safely transition to significantly reduced nicotine content cigarettes."5.24A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol. ( Allen, SI; Azzouz, N; Cather, C; Evins, AE; Foulds, J; Hameed, A; Hammett, E; Hrabovsky, S; Krebs, NM; Liao, J; Modesto, J; Muscat, JE; Pachas, GN; Richie, J; Veldheer, S; Yingst, J; Zhu, J, 2017)
"In this case report, a 40-year-old male with a past medical history of depression, anxiety, panic attacks, and substance use disorder developed symptomatic, acute carbon monoxide poisoning secondary to heavy cigarette smoking in a confined space."3.91Acute Carbon Monoxide Poisoning Secondary to Cigarette Smoking in a 40-Year-Old Man: A Case Report. ( Aloi, J; Neilsen, BK; Sharma, A, 2019)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Pałasz, A1
Menezes, IC1
Worthington, JJ1
Neilsen, BK1
Aloi, J1
Sharma, A1
Furlanetto, KC1
Mantoani, LC1
Bisca, G1
Morita, AA1
Zabatiero, J1
Proença, M1
Kovelis, D1
Pitta, F1
Capron, DW1
Norr, AM1
Allan, NP1
Schmidt, NB1
Allen, SI1
Foulds, J1
Pachas, GN1
Veldheer, S1
Cather, C1
Azzouz, N1
Hrabovsky, S1
Hameed, A1
Yingst, J1
Hammett, E1
Modesto, J1
Krebs, NM1
Zhu, J1
Liao, J1
Muscat, JE1
Richie, J1
Evins, AE1
Reiman, EM1
Raichle, ME1
Robins, E1
Butler, FK1
Herscovitch, P1
Fox, P1
Perlmutter, J1
Shear, MK1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Association of Cigarette Smoking on Exercise Capacity and Skeletal Muscle Function in Taiwan Adult Smokers[NCT04688177]52 participants (Actual)Observational2020-12-03Completed
Reduced Nicotine Cigarettes in Smokers With Mood and Anxiety Disorders[NCT01928758]245 participants (Actual)Interventional2015-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Abstinence From Smoking

Smokers assigned to reduced nicotine content cigarettes will be more likely to successfully abstain from smoking at the end of the trial, based on all randomized participants, defined as no cigarette use in past 7 days, verified by exhaled carbon monoxide <10ppm. (NCT01928758)
Timeframe: Follow-up appointment 30 weeks after randomization (12 weeks after last visit of randomized trial phase).

InterventionParticipants (Count of Participants)
Reduced Nicotine Content Cigarettes17
Usual Nicotine Content Cigarettes4

Intention to Quit Smoking

Smokers assigned to the reduced nicotine content cigarette group may have lower perceived dependence and be more likely to report intention to quit smoking (NCT01928758)
Timeframe: At end of 18-week randomized trial phase

InterventionParticipants (Count of Participants)
Reduced Nicotine Content Cigarettes33
Usual Nicotine Content Cigarettes25

Minnesota Nicotine Withdrawal Scale

This 8-item scale measures nicotine withdrawal symptoms and the scale range is from 0-32. Higher scores indicate higher severity. (NCT01928758)
Timeframe: Measured at the end of the last 3 weeks of randomization trial phase

Interventionscore on a scale (Mean)
Reduced Nicotine Content Cigarettes8.1
Usual Nicotine Content Cigarettes9.0

Perceived Stress Scale

10-item questionnaire measuring the degree to which life situations are appraised stressful. Scale range is 0-40. Higher scores indicate more stress. (NCT01928758)
Timeframe: Measured at the end of the last 3 weeks of randomization trial phase

Interventionscore on a scale (Mean)
Reduced Nicotine Content Cigarettes15.0
Usual Nicotine Content Cigarettes15.1

Plasma Cotinine Concentration

Plasma cotinine is a measure of daily nicotine exposure. Samples were measured in ng/mL. (NCT01928758)
Timeframe: Measured at the end of the last 3 weeks of randomization trial phase

Interventionng/mL (Mean)
Reduced Nicotine Content Cigarettes82.8
Usual Nicotine Content Cigarettes259.0

Quick Inventory of Depressive Symptomatology

A 16-item scale on depression symptoms. The scale range is 0-27 where 0 = Least Severe and 27 = Most Severe. (NCT01928758)
Timeframe: Measured at the end of the last 3 weeks of randomization trial phase

Interventionscore on a scale (Mean)
Reduced Nicotine Content Cigarettes5.5
Usual Nicotine Content Cigarettes5.3

Reviews

2 reviews available for carbon monoxide and Anxiety Disorders

ArticleYear
The role of brain gaseous neurotransmitters in anxiety.
    Pharmacological reports : PR, 2021, Volume: 73, Issue:2

    Topics: Animals; Anxiety; Anxiety Disorders; Brain; Carbon Monoxide; Gasotransmitters; Humans; Hydrogen Sulf

2021
Pathophysiology of panic: a review of pharmacologic provocative tests and naturalistic monitoring data.
    The Journal of clinical psychiatry, 1986, Volume: 47 Suppl

    Topics: Anxiety Disorders; Arousal; Caffeine; Calmodulin; Carbon Monoxide; Fear; Humans; Imagination; Isopro

1986

Trials

2 trials available for carbon monoxide and Anxiety Disorders

ArticleYear
Combined "top-down" and "bottom-up" intervention for anxiety sensitivity: Pilot randomized trial testing the additive effect of interpretation bias modification.
    Journal of psychiatric research, 2017, Volume: 85

    Topics: Adolescent; Anxiety; Anxiety Disorders; Carbon Monoxide; Cognitive Behavioral Therapy; Female; Follo

2017
A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol.
    BMC public health, 2017, 01-19, Volume: 17, Issue:1

    Topics: Adult; Anxiety Disorders; Biomarkers; Carbon Monoxide; Clinical Protocols; Cotinine; Double-Blind Me

2017

Other Studies

3 other studies available for carbon monoxide and Anxiety Disorders

ArticleYear
Acute Carbon Monoxide Poisoning Secondary to Cigarette Smoking in a 40-Year-Old Man: A Case Report.
    The American journal on addictions, 2019, Volume: 28, Issue:5

    Topics: Adult; Anxiety Disorders; Benzodiazepines; Carbon Monoxide; Carbon Monoxide Poisoning; Cigarette Smo

2019
Reduction of physical activity in daily life and its determinants in smokers without airflow obstruction.
    Respirology (Carlton, Vic.), 2014, Volume: 19, Issue:3

    Topics: Activities of Daily Living; Adult; Anxiety Disorders; Carbon Monoxide; Comorbidity; Cross-Sectional

2014
The application of positron emission tomography to the study of panic disorder.
    The American journal of psychiatry, 1986, Volume: 143, Issue:4

    Topics: Adult; Anxiety Disorders; Brain; Carbon Monoxide; Cerebrovascular Circulation; Fear; Female; Functio

1986
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