Page last updated: 2024-10-16

carbon monoxide and Anemia, Sickle Cell

carbon monoxide has been researched along with Anemia, Sickle Cell in 50 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.

Research Excerpts

ExcerptRelevanceReference
"Carbon monoxide (CO) production from heme catabolism is increased with hemolysis."7.81Point-of-care end-tidal carbon monoxide reflects severity of hemolysis in sickle cell anemia. ( Goldrich, A; Lal, A; Marsh, A; Patterson, L, 2015)
"In this study, the authors examined a possible role of measurements of end-tidal carbon monoxide (CO), corrected for inhaled CO (ETCOc), as a noninvasive screening tool for hemoglobinopathies and as an indicator for when transfusions would be required in patients receiving chronic transfusions."7.76Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy. ( Golden, DW; Hall, JY; Harmatz, P; James, EB; Schumacher, L; Simon, J; Stevenson, DK; Vichinsky, E; Vreman, HJ; Wong, RJ, 2010)
"Carbon monoxide (CO) has anti-inflammatory properties."5.35Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease. ( Beckman, JD; Belcher, JD; Chen, C; Gulbahce, E; Hebbel, RP; Nguyen, J; Nwaneri, MO; O'Sullivan, MG; Vercellotti, GM; Vineyard, JV, 2009)
"Carbon monoxide (CO) production from heme catabolism is increased with hemolysis."3.81Point-of-care end-tidal carbon monoxide reflects severity of hemolysis in sickle cell anemia. ( Goldrich, A; Lal, A; Marsh, A; Patterson, L, 2015)
"In this study, the authors examined a possible role of measurements of end-tidal carbon monoxide (CO), corrected for inhaled CO (ETCOc), as a noninvasive screening tool for hemoglobinopathies and as an indicator for when transfusions would be required in patients receiving chronic transfusions."3.76Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy. ( Golden, DW; Hall, JY; Harmatz, P; James, EB; Schumacher, L; Simon, J; Stevenson, DK; Vichinsky, E; Vreman, HJ; Wong, RJ, 2010)
"A hemolysis-linked subphenotype of sickle cell disease (SCD), characterized by pulmonary hypertension, stroke, priapism and leg ulcers, is associated with decreased nitric oxide bioavailability and vasculopathy."1.35Novel small molecule therapeutics for sickle cell disease: nitric oxide, carbon monoxide, nitrite, and apolipoprotein A-I. ( Kato, GJ, 2008)
"Carbon monoxide (CO) has anti-inflammatory properties."1.35Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease. ( Beckman, JD; Belcher, JD; Chen, C; Gulbahce, E; Hebbel, RP; Nguyen, J; Nwaneri, MO; O'Sullivan, MG; Vercellotti, GM; Vineyard, JV, 2009)
"Pulmonary complications of sickle cell anemia (Hb-SS) commonly cause morbidity, yet few large studies of pulmonary function tests (PFTs) in this population have been reported."1.33Abnormal pulmonary function in adults with sickle cell anemia. ( Klings, ES; Nolan, VG; Steinberg, MH; Wyszynski, DF, 2006)
"A young women with sickle cell anemia was admitted with a typical painful crisis, and was found to have a PCV of 39% with a reticulocyte count of 3."1.26Increased blood viscosity in a patient with sickle cell anemia. ( Charache, S; de la Monte, S; MacDonald, V, 1982)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199025 (50.00)18.7374
1990's3 (6.00)18.2507
2000's8 (16.00)29.6817
2010's13 (26.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
van Vuren, AJ1
Minniti, CP1
Mendelsohn, L1
Baird, JH1
Kato, GJ2
van Beers, EJ1
Gomperts, E2
Belcher, JD5
Otterbein, LE3
Coates, TD1
Wood, J1
Skolnick, BE1
Levy, H2
Vercellotti, GM5
Abuchowski, A1
Chen, C4
Nguyen, J4
Abdulla, F2
Zhang, P1
Nguyen, H1
Nguyen, P1
Killeen, T1
Miescher, SM1
Brinkman, N1
Nath, KA1
Steer, CJ1
Tackett, AP1
Leavens, ELS1
Wiedenmann, A1
Perez, MN1
Baker, A1
Mayes, S1
Mullins, LL1
Wagener, TL1
Kiser, ZM1
Gallo, D1
Al-Khabori, M1
Al-Hashim, A1
Jabeen, Z1
Al-Farsi, K1
Al-Huneini, M1
Al-Riyami, A1
Al-Kemyani, N1
Daar, S1
Young, M1
Burhop, K1
Tran, P1
Araujo, JA1
Mekontso Dessap, A1
Contou, D1
Dandine-Roulland, C1
Hemery, F1
Habibi, A1
Charles-Nelson, A1
Galacteros, F1
Brun-Buisson, C1
Maitre, B1
Katsahian, S1
Lal, A1
Patterson, L1
Goldrich, A1
Marsh, A1
Lunt, A1
McGhee, E1
Robinson, P1
Rees, D2
Height, S1
Greenough, A3
Beckman, JD1
Vineyard, JV1
Nwaneri, MO1
O'Sullivan, MG1
Gulbahce, E1
Hebbel, RP1
Vandorpe, DH1
Xu, C1
Shmukler, BE1
Trudel, M1
Sachs, F1
Gottlieb, PA1
Brugnara, C1
Alper, SL1
James, EB1
Vreman, HJ1
Wong, RJ1
Stevenson, DK1
Vichinsky, E1
Schumacher, L1
Hall, JY1
Simon, J1
Golden, DW1
Harmatz, P1
SIRS, JA1
PURUGGANAN, HB1
MCELFRESH, AE1
Sylvester, KP2
Patey, RA1
Rafferty, GF1
Thein, SL3
Klings, ES1
Wyszynski, DF1
Nolan, VG1
Steinberg, MH1
Desai, SR1
Wells, AU1
Hansell, DM1
Awogbade, M1
O'Malley, GF1
Yallop, D1
Duncan, ER1
Norris, E1
Fuller, GW1
Thomas, N1
Walters, J1
Dick, MC1
Height, SE1
Rees, DC1
Adachi, K1
Kinney, TR1
Schwartz, E1
Asakura, T1
Charache, S1
de la Monte, S1
MacDonald, V1
Antonini, E3
Brunori, M3
Giardina, B3
Benedetti, PA3
Grassi, S3
Gualtieri, P1
Shapiro, DB1
Esquerra, RM1
Goldbeck, RA1
Ballas, SK2
Mohandas, N1
Kliger, DS1
Louderback, JG1
Aroutiounian, SK1
Kerr, WC1
Kim-Shapiro, DB1
Kiessling, K1
Roberts, N1
Gibson, JS1
Ellory, JC1
Beutler, E1
Bianchini, G2
Miller, GJ2
Serjeant, GR2
Saunders, MJ1
Richardson, C1
Gilson, RJ1
Milosz, A1
Settle, W1
Ogawa, E1
Hasegawa, M1
Fujise, H1
Kobayashi, K1
Solanki, DL1
McCurdy, PR2
Cuttitta, FF1
Schechter, GP1
Mozzarelli, A1
Hofrichter, J1
Eaton, WA1
Slovis, CM1
Talley, JD1
Pitts, RB1
Rodgers, GP1
Noguchi, CT1
Schechter, AN1
Pimstone, NR1
Bensinger, TA3
Gillette, PN1
Glader, BE1
Conrad, ME2
Moon, RB1
Nelson, MJ1
Richards, JH1
Powars, DF1
Bunn, HF2
McDonough, M1
Segel, GB1
Feig, SA1
Mentzer, WC1
McCaffrey, RP1
Wells, R1
Shohet, SB1
Nathan, DG1
Maisels, MJ1
Mahmood, L1
Engel, RR1
Rodkey, FL1
Krill, CE1
Lawson, WH1
Femi-Pearse, D1
Gazioglu, KM1
Yu, PN1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
End-Alveolar Carbon Monoxide as a Measure of Erythrocyte Survival and Hemolytic Severity in Sickle Cell Disease[NCT01547793]106 participants (Actual)Observational2012-01-26Completed
Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients With Sickle Cell Anemia[NCT00011648]986 participants (Actual)Observational2008-02-19Completed
Impact of E-cigarette Nicotine Concentration on Compensation, Cigarette Smoking, and Biomarkers of Exposure and Harm in Diverse Smokers[NCT05887947]48 participants (Anticipated)Interventional2023-02-20Recruiting
A Phase 2 Multi-center, Randomized, Double-blind, Comparator-Controlled Dose Finding Study to Evaluate MP4CO for the Acute Treatment of Vaso-occlusive Crises in Subjects With Sickle Cell Disease[NCT01925001]Phase 20 participants (Actual)Interventional2013-10-31Withdrawn (stopped due to Sangart ceased operations)
Point-of-Care End-Tidal Carbon Monoxide Measurement to Screen for Sickle Cell Disease[NCT02530242]32 participants (Actual)Interventional2015-07-31Completed
Aerobic Physical Fitness and Health-related Quality of Life in Children With Sickle Cell Disease.[NCT05995743]72 participants (Actual)Observational2021-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

End-Tidal Carbon Monoxide

Compare ETCO between subjects and controls (NCT02530242)
Timeframe: 1 hour

Interventionppm (Median)
End-tidal Carbon Monoxide Subjects4.35
End-tidal Carbon Monoxide Controls.80

Reviews

3 reviews available for carbon monoxide and Anemia, Sickle Cell

ArticleYear
The role of carbon monoxide and heme oxygenase in the prevention of sickle cell disease vaso-occlusive crises.
    American journal of hematology, 2017, Volume: 92, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Carbon Monoxide; Clinical Trials as Topic; Disease Models, Animal; Hem

2017
Renal degradation of hemoglobin.
    Seminars in hematology, 1972, Volume: 9, Issue:1

    Topics: Amino Acids; Anemia, Hemolytic; Anemia, Sickle Cell; Animals; Bilirubin; Carbon Isotopes; Carbon Mon

1972
Hemolysis in sickle cell disease.
    Archives of internal medicine, 1974, Volume: 133, Issue:4

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Carbon Monoxide; Carbon Radioisotopes; Child; Chromium Radio

1974

Trials

1 trial available for carbon monoxide and Anemia, Sickle Cell

ArticleYear
Lactate dehydrogenase to carboxyhemoglobin ratio as a biomarker of heme release to heme processing is associated with higher tricuspid regurgitant jet velocity and early death in sickle cell disease.
    American journal of hematology, 2021, 09-01, Volume: 96, Issue:9

    Topics: Adult; Anemia, Sickle Cell; Biomarkers; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemolysis; Humans;

2021
Lactate dehydrogenase to carboxyhemoglobin ratio as a biomarker of heme release to heme processing is associated with higher tricuspid regurgitant jet velocity and early death in sickle cell disease.
    American journal of hematology, 2021, 09-01, Volume: 96, Issue:9

    Topics: Adult; Anemia, Sickle Cell; Biomarkers; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemolysis; Humans;

2021
Lactate dehydrogenase to carboxyhemoglobin ratio as a biomarker of heme release to heme processing is associated with higher tricuspid regurgitant jet velocity and early death in sickle cell disease.
    American journal of hematology, 2021, 09-01, Volume: 96, Issue:9

    Topics: Adult; Anemia, Sickle Cell; Biomarkers; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemolysis; Humans;

2021
Lactate dehydrogenase to carboxyhemoglobin ratio as a biomarker of heme release to heme processing is associated with higher tricuspid regurgitant jet velocity and early death in sickle cell disease.
    American journal of hematology, 2021, 09-01, Volume: 96, Issue:9

    Topics: Adult; Anemia, Sickle Cell; Biomarkers; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemolysis; Humans;

2021

Other Studies

46 other studies available for carbon monoxide and Anemia, Sickle Cell

ArticleYear
SANGUINATE (PEGylated Carboxyhemoglobin Bovine): Mechanism of Action and Clinical Update.
    Artificial organs, 2017, Volume: 41, Issue:4

    Topics: Anemia; Anemia, Sickle Cell; Animals; Blood Substitutes; Brain Ischemia; Carbon Monoxide; Carboxyhem

2017
Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Aldehydes; Anemia, Sickle Cell; Animals; Carbon Monoxide; Cytokines; Disease Models, Animal; Female;

2018
Preliminary exploration of secondhand smoke exposure in youth with Sickle Cell Disease: biochemical verification, pulmonary functioning, and health care utilization.
    Psychology, health & medicine, 2019, Volume: 24, Issue:1

    Topics: Adolescent; Anemia, Sickle Cell; Carbon Monoxide; Child; Cotinine; Emergency Service, Hospital; Fema

2019
Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Administration, Oral; Anemia, Sickle Cell; Animals; Antisickling Agents; Carbon Monoxide; Disease Mo

2018
Validation of a noninvasive pulse CO-oximetry-based hemoglobin estimation in patients with sickle cell disease.
    International journal of laboratory hematology, 2013, Volume: 35, Issue:5

    Topics: Anemia, Sickle Cell; Carbon Monoxide; Hemoglobins; Humans; Oximetry; Prospective Studies; Reproducib

2013
MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice.
    Blood, 2013, Oct-10, Volume: 122, Issue:15

    Topics: Anemia, Sickle Cell; Animals; Carbon Monoxide; Disease Models, Animal; Female; Guaiacol; Heme Oxygen

2013
HO-1 and CO: fighters vs sickle cell disease?
    Blood, 2013, Oct-10, Volume: 122, Issue:15

    Topics: Anemia, Sickle Cell; Animals; Carbon Monoxide; Female; Heme Oxygenase-1; Hemoglobins; Humans; Male;

2013
Environmental influences on daily emergency admissions in sickle-cell disease patients.
    Medicine, 2014, Volume: 93, Issue:29

    Topics: Air Pollutants; Anemia, Sickle Cell; Carbon Monoxide; Emergency Service, Hospital; Humans; Multivari

2014
Point-of-care end-tidal carbon monoxide reflects severity of hemolysis in sickle cell anemia.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:5

    Topics: Adolescent; Anemia, Sickle Cell; Bilirubin; Carbon Monoxide; Case-Control Studies; Child; Child, Pre

2015
Lung function, transfusion, pulmonary capillary blood volume and sickle cell disease.
    Respiratory physiology & neurobiology, 2016, Feb-01, Volume: 222

    Topics: Adolescent; Anemia, Sickle Cell; Blood Transfusion; Blood Volume; Blood Volume Determination; Capill

2016
Novel small molecule therapeutics for sickle cell disease: nitric oxide, carbon monoxide, nitrite, and apolipoprotein A-I.
    Hematology. American Society of Hematology. Education Program, 2008

    Topics: Analgesics; Anemia, Sickle Cell; Apolipoprotein A-I; Carbon Monoxide; Clinical Trials as Topic; Cycl

2008
Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:4

    Topics: Administration, Inhalation; Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Apoferritins; Ca

2009
Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.
    PloS one, 2010, Jan-15, Volume: 5, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Animals; Calcium; Calcium Cha

2010
Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy.
    Pediatric hematology and oncology, 2010, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Breath Tests; Carbon Monoxide; Child; Child, Preschool; Cros

2010
The use of carbon monoxide to prevent sickle-cell formation.
    Lancet (London, England), 1963, May-04, Volume: 1, Issue:7288

    Topics: Anemia; Anemia, Sickle Cell; Carbon Monoxide

1963
FAILURE OF CARBONMONOXY SICKLE-CELL HAEMOGLOBIN TO ALTER THE SICKLE STATE.
    Lancet (London, England), 1964, Jan-11, Volume: 1, Issue:7324

    Topics: Anemia; Anemia, Sickle Cell; Blood Gas Analysis; Carbon Monoxide; Child; Hemoglobin, Sickle; Hemoglo

1964
Exhaled carbon monoxide levels in children with sickle cell disease.
    European journal of pediatrics, 2005, Volume: 164, Issue:3

    Topics: Adolescent; Age Factors; Anemia, Sickle Cell; Bilirubin; Breath Tests; Carbon Monoxide; Case-Control

2005
Abnormal pulmonary function in adults with sickle cell anemia.
    American journal of respiratory and critical care medicine, 2006, Jun-01, Volume: 173, Issue:11

    Topics: Acute Disease; Adult; Aged; Anemia, Sickle Cell; Carbon Monoxide; Female; Humans; Logistic Models; L

2006
Computed tomography and pulmonary function abnormalities in sickle cell disease.
    The European respiratory journal, 2006, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Biomarkers; Breath Tests; Carbon Monoxide; Female; Hem

2006
Non-invasive carbon monoxide measurement is not accurate.
    Annals of emergency medicine, 2006, Volume: 48, Issue:4

    Topics: Anemia, Sickle Cell; Artifacts; Calibration; Carbon Monoxide; Carboxyhemoglobin; Emergency Service,

2006
The associations between air quality and the number of hospital admissions for acute pain and sickle-cell disease in an urban environment.
    British journal of haematology, 2007, Volume: 136, Issue:6

    Topics: Acute Disease; Adult; Air Pollutants; Air Pollution; Analysis of Variance; Anemia, Sickle Cell; Carb

2007
Molecular stability and function of Hb C-Harlem.
    Hemoglobin, 1980, Volume: 4, Issue:1

    Topics: Amino Acid Sequence; Anemia, Sickle Cell; Carbon Monoxide; Chemical Phenomena; Chemical Precipitatio

1980
Increased blood viscosity in a patient with sickle cell anemia.
    Blood cells, 1982, Volume: 8, Issue:1

    Topics: Acute Disease; Adult; Anemia, Sickle Cell; Blood Viscosity; Carbon Monoxide; Carbon Monoxide Poisoni

1982
Kinetics of reactions within single erythrocytes: studies by microspectrophotometry.
    Haematologia, 1982, Volume: 15, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Binding Sites; Carbon Monoxide; Erythrocytes; Erythrocytes, Abnormal;

1982
Carbon monoxide religation kinetics to hemoglobin S polymers following ligand photolysis.
    The Journal of biological chemistry, 1995, Nov-03, Volume: 270, Issue:44

    Topics: Anemia, Sickle Cell; Carbon Monoxide; Hemoglobin, Sickle; Humans; Kinetics; Ligands; Models, Theoret

1995
Temperature and domain size dependence of sickle cell hemoglobin polymer melting in high concentration phosphate buffer.
    Biophysical chemistry, 1999, Jul-19, Volume: 80, Issue:1

    Topics: Adult; Anemia, Sickle Cell; Biophysical Phenomena; Biophysics; Biopolymers; Buffers; Carbon Monoxide

1999
A comparison in normal individuals and sickle cell patients of reduced glutathione precursors and their transport between plasma and red cells.
    The hematology journal : the official journal of the European Haematology Association, 2000, Volume: 1, Issue:4

    Topics: Adult; Amino Acid Transport System ASC; Amino Acid Transport System L; Anemia, Sickle Cell; Biologic

2000
The effect of carbon monoxide on red cell life span in sickle cell disease.
    Blood, 1975, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Carbon Monoxide; Carboxyhemoglobin; Cell Biology; Cell Survi

1975
Kinetics of the reaction with CO of human erythrocytes. Observations by single cell spectroscopy.
    FEBS letters, 1978, Feb-15, Volume: 86, Issue:2

    Topics: Anemia, Sickle Cell; Carbon Monoxide; Densitometry; Erythrocytes; Hemoglobins; Humans; Kinetics; Pho

1978
Interpretation of lung function tests in the sickle-cell haemoglobinopathies.
    Thorax, 1978, Volume: 33, Issue:1

    Topics: Adult; Age Factors; Anemia, Sickle Cell; Black People; Carbon Monoxide; Female; Hemoglobin C; Hemogl

1978
Single cell observations of gas reactions and shape changes in normal and sickling erythrocytes.
    Biophysical journal, 1978, Volume: 24, Issue:1

    Topics: Anemia, Sickle Cell; Carbon Monoxide; Diffusion; Erythrocytes; Erythrocytes, Abnormal; Kinetics; Pho

1978
A new approach to the treatment of sickle cell anemia.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 12, Issue:1

    Topics: Anemia, Sickle Cell; Binding Sites; Carbon Monoxide; Hemoglobin, Sickle; Humans; Ligands; Methylene

1975
Erythrocyte sickling in sika deer (Cervus nippon).
    The Journal of veterinary medical science, 1991, Volume: 53, Issue:6

    Topics: Air; Anemia, Sickle Cell; Animals; Breeding; Carbon Dioxide; Carbon Monoxide; Cells, Cultured; Deer;

1991
Hemolysis in sickle cell disease as measured by endogenous carbon monoxide production. A preliminary report.
    American journal of clinical pathology, 1988, Volume: 89, Issue:2

    Topics: Anemia, Sickle Cell; Carbon Monoxide; Cell Survival; Erythrocytes; Hematology; Hemoglobin C Disease;

1988
Delay time of hemoglobin S polymerization prevents most cells from sickling in vivo.
    Science (New York, N.Y.), 1987, Jul-31, Volume: 237, Issue:4814

    Topics: Anemia, Sickle Cell; Biopolymers; Carbon Monoxide; Erythrocytes, Abnormal; Gels; Hemoglobin, Sickle;

1987
Non relationship of climatologic factors and painful sickle cell anemia crisis.
    Journal of chronic diseases, 1986, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Carbon Monoxide; Child; Climate; Cold Temperature; Computers

1986
Irreversibly sickled erythrocytes in sickle cell anemia: a quantitative reappraisal.
    American journal of hematology, 1985, Volume: 20, Issue:1

    Topics: Anemia, Sickle Cell; Carbon Monoxide; Erythrocyte Count; Erythrocytes; Humans; Oxygen

1985
Intravascular hemolysis associated with intravenous urea infusions in normal individuals.
    Blood, 1973, Volume: 41, Issue:3

    Topics: Adult; Anemia, Sickle Cell; Carbon Monoxide; Cell Membrane; Erythrocytes; Erythrocytes, Abnormal; He

1973
13C magnetic resonance studies of hemoglobin carbamylation.
    Physiological chemistry and physics, 1974, Volume: 6, Issue:1

    Topics: Adult; Amino Acid Sequence; Anemia, Sickle Cell; Binding Sites; Carbon Isotopes; Carbon Monoxide; Ca

1974
Asymmetrical hemoglobin hybrids. An approach to the study of subunit interactions.
    Biochemistry, 1974, Feb-26, Volume: 13, Issue:5

    Topics: Anemia, Hemolytic; Anemia, Sickle Cell; Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cya

1974
Effects of urea and cyanate on sickling in vitro.
    The New England journal of medicine, 1972, Jul-13, Volume: 287, Issue:2

    Topics: Anemia, Sickle Cell; Blood Urea Nitrogen; Blood Viscosity; Carbon Monoxide; Cyanates; Erythrocytes;

1972
An assessment of lung volumes and gas transfer in sickle-cell anaemia.
    Thorax, 1971, Volume: 26, Issue:3

    Topics: Adult; Anemia, Sickle Cell; Anthropometry; Blood Volume; Body Height; Body Weight; Carbon Monoxide;

1971
Effect of intravenous urea in invert sugar on heme catabolism in sickle-cell anemia.
    The New England journal of medicine, 1971, Oct-28, Volume: 285, Issue:18

    Topics: Anemia, Sickle Cell; Bilirubin; Blood Urea Nitrogen; Carbon Monoxide; Erythrocyte Count; Female; Fru

1971
Carboxyhemoglobin levels as an index of hemolysis.
    Pediatrics, 1971, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Carbon Mon

1971
Effect of anemia, species, and temperature on CO kinetics with red blood cells.
    Journal of applied physiology, 1971, Volume: 31, Issue:3

    Topics: Anemia; Anemia, Hypochromic; Anemia, Sickle Cell; Animals; Blood Volume; Capillary Permeability; Car

1971
Pulmonary function studies in sickle cell disease.
    Journal of applied physiology, 1970, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Blood Volume; Capillary Permeability; Carbon Monoxide; Diffu

1970