Page last updated: 2024-10-16

carbon monoxide and Alzheimer Disease

carbon monoxide has been researched along with Alzheimer Disease in 7 studies

Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"Neurodegeneration in Alzheimer's disease (AD) is extensively studied, and the involvement of astrocytes and other cell types in this process has been described."1.46Heme oxygenase-1 derived carbon monoxide suppresses Aβ ( Al-Owais, MM; Boyle, JP; Dallas, ML; Hettiarachchi, NT; Peers, C; Scragg, JL, 2017)
" Protection does not arise from inhibition of apoptosis-associated K+ efflux, but rather by inhibition of AMPK activation, which has been recently implicated in the toxic effects of Aβ."1.40Heme oxygenase-1 protects against Alzheimer's amyloid-β(1-42)-induced toxicity via carbon monoxide production. ( Al-Owais, M; Boyle, J; Dallas, M; Griffiths, H; Hettiarachchi, N; Hooper, N; Peers, C; Scragg, J, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shefa, U1
Yeo, SG1
Kim, MS1
Song, IO1
Jung, J1
Jeong, NY1
Huh, Y1
Hettiarachchi, NT1
Boyle, JP1
Dallas, ML1
Al-Owais, MM1
Scragg, JL1
Peers, C2
Hettiarachchi, N1
Dallas, M1
Al-Owais, M1
Griffiths, H1
Hooper, N1
Scragg, J1
Boyle, J1
Nielsen, VG1
Pretorius, E1
Bester, J1
Jacobsen, WK1
Boyle, PK1
Reinhard, JP1
Neumann, KT1
Lindhardt, AT1
Bang-Andersen, B1
Skrydstrup, T1
Sagnou, M1
Benaki, D1
Triantis, C1
Tsotakos, T1
Psycharis, V1
Raptopoulou, CP1
Pirmettis, I1
Papadopoulos, M1
Pelecanou, M1
Cuadrado, A1
Rojo, AI1

Reviews

2 reviews available for carbon monoxide and Alzheimer Disease

ArticleYear
Role of Gasotransmitters in Oxidative Stresses, Neuroinflammation, and Neuronal Repair.
    BioMed research international, 2017, Volume: 2017

    Topics: Alzheimer Disease; Carbon Monoxide; Cardiovascular System; Gasotransmitters; Humans; Hydrogen Sulfid

2017
Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections.
    Current pharmaceutical design, 2008, Volume: 14, Issue:5

    Topics: Alzheimer Disease; Animals; Biliverdine; Brain; Carbon Monoxide; Central Nervous System Infections;

2008

Other Studies

5 other studies available for carbon monoxide and Alzheimer Disease

ArticleYear
Heme oxygenase-1 derived carbon monoxide suppresses Aβ
    Cell death & disease, 2017, 06-15, Volume: 8, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Antioxidants; Astrocytes; Carbo

2017
Heme oxygenase-1 protects against Alzheimer's amyloid-β(1-42)-induced toxicity via carbon monoxide production.
    Cell death & disease, 2014, Dec-11, Volume: 5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Carbon Monoxide; Cell Survival; Cells,

2014
Carbon monoxide and iron modulate plasmatic coagulation in Alzheimer's disease.
    Current neurovascular research, 2015, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood Coagulation; Carbon Monoxide; Cohort Studies; Fema

2015
Access to 2-(Het)aryl and 2-Styryl Benzoxazoles via Palladium-Catalyzed Aminocarbonylation of Aryl and Vinyl Bromides.
    Organic letters, 2015, May-01, Volume: 17, Issue:9

    Topics: Alzheimer Disease; Aminophenols; Benzoxazoles; Carbon Monoxide; Catalysis; Hydrocarbons, Brominated;

2015
Curcumin as the OO bidentate ligand in "2 + 1" complexes with the [M(CO)3]+ (M = Re, 99mTc) tricarbonyl core for radiodiagnostic applications.
    Inorganic chemistry, 2011, Feb-21, Volume: 50, Issue:4

    Topics: Alzheimer Disease; Brain; Carbon Monoxide; Crystallography, X-Ray; Curcumin; Cyclohexanes; Humans; I

2011