carbon monoxide has been researched along with Acute Lung Injury in 30 studies
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
Excerpt | Relevance | Reference |
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"Carbon monoxide (CO) has been reported to exhibit a therapeutic effect in lipopolysaccharide (LPS)-induced acute lung injury (ALI)." | 8.31 | Carbon monoxide ameliorates lipopolysaccharide-induced acute lung injury via inhibition of alveolar macrophage pyroptosis. ( Huang, X; Li, W; Qian, G; Wang, H; Wang, X; Xu, W; Zhou, B, 2023) |
"Low-dose inhaled carbon monoxide is reported to suppress inflammatory responses and exhibit a therapeutic effect in models of lipopolysaccharide (LPS)-induced acute lung injury (ALI)." | 7.81 | Tristetraprolin mediates anti-inflammatory effects of carbon monoxide on lipopolysaccharide-induced acute lung injury. ( Chen, Y; Cho, GJ; Chung, HT; Joe, Y; Kim, SK; Lee, JH; Park, JW; Yang, JW, 2015) |
" In this study, we assessed the role of CO donor, methylene chloride (MC), on modulation of lung inflammation during sepsis." | 7.76 | Methylene chloride protects against cecal ligation and puncture-induced acute lung injury by modulating inflammatory mediators. ( Dou, L; He, J; Pan, X; Pang, Q; Xu, W; Zeng, S; Zeng, Y, 2010) |
"To explore the role of hydrogen sulfide/cystathionine-gamma-lyase (H(2)S/CSE) system in lipopolysaccharide (LPS)- induced acute lung injury (ALI) in rats and the underlying mechanisms." | 7.75 | [Role of hydrogen sulfide/cystathionine-gamma-lyase system in acute lung injury induced by lipopolysaccharide in rats]. ( Huang, XL; Ling, YL; Tian, FJ; Wei, P; Zhou, XH, 2009) |
"To explore the role of endogenous and exogenous hydrogen sulfide (H2S) in lipopolysaccharide (LPS)-induced acute lung injury (ALI) in rats and the underlying mechanisms." | 7.75 | [Role of endogenous and exogenous hydrogen sulfide in acute lung injury induced by LPS in rats]. ( Huang, XL; Ling, YL; Wei, P; Zhou, XH, 2009) |
"To explore the role of hydrogen sulfide (H2S) in acute lung injury (ALI) during endotoxic shock (ES) and its relationship with nitric oxide (NO) and carbon monoxide (CO)." | 7.74 | [The role of hydrogen sulfide in acute lung injury during endotoxic shock and its relationship with nitric oxide and carbon monoxide]. ( Huang, XL; Ling, YL; Wei, P; Xian, XH; Zhou, XH, 2008) |
"To investigate the effects of carbon monoxide (CO) inhalation on the apoptosis of pulmonary cells in rats with acute lung injury (ALI) induced by lipopolysaccharide (LPS) and to investigate its mechanisms." | 7.73 | [The mechanisms of carbon monoxide inhalation on the apoptosis of pulmonary cells in rats with acute lung injury induced by lipopolysaccharide]. ( Liu, SH; Ma, K; Xu, B; Xu, XR, 2006) |
"Even after successful resuscitation, hemorrhagic shock frequently causes pulmonary inflammation that induces acute lung injury (ALI)." | 5.39 | Inhalation of carbon monoxide following resuscitation ameliorates hemorrhagic shock-induced lung injury. ( Kawanishi, S; Maeda, S; Matsumi, M; Morimatsu, H; Morita, K; Nakao, A; Omori, E; Sato, K; Shimizu, H; Takahashi, T, 2013) |
"Carbon monoxide (CO) has been reported to exhibit a therapeutic effect in lipopolysaccharide (LPS)-induced acute lung injury (ALI)." | 4.31 | Carbon monoxide ameliorates lipopolysaccharide-induced acute lung injury via inhibition of alveolar macrophage pyroptosis. ( Huang, X; Li, W; Qian, G; Wang, H; Wang, X; Xu, W; Zhou, B, 2023) |
"Low-dose inhaled carbon monoxide is reported to suppress inflammatory responses and exhibit a therapeutic effect in models of lipopolysaccharide (LPS)-induced acute lung injury (ALI)." | 3.81 | Tristetraprolin mediates anti-inflammatory effects of carbon monoxide on lipopolysaccharide-induced acute lung injury. ( Chen, Y; Cho, GJ; Chung, HT; Joe, Y; Kim, SK; Lee, JH; Park, JW; Yang, JW, 2015) |
" In this study, we assessed the role of CO donor, methylene chloride (MC), on modulation of lung inflammation during sepsis." | 3.76 | Methylene chloride protects against cecal ligation and puncture-induced acute lung injury by modulating inflammatory mediators. ( Dou, L; He, J; Pan, X; Pang, Q; Xu, W; Zeng, S; Zeng, Y, 2010) |
"Carbon monoxide (CO) is currently being evaluated as a therapeutic modality in the treatment of patients with acute lung injury and acute respiratory distress syndrome." | 3.75 | Carbon monoxide rapidly impairs alveolar fluid clearance by inhibiting epithelial sodium channels. ( Althaus, M; Buchäckert, Y; Clauss, WG; Fronius, M; Morty, RE; Motterlini, R; Seeger, W; Vadász, I, 2009) |
"To explore the role of hydrogen sulfide/cystathionine-gamma-lyase (H(2)S/CSE) system in lipopolysaccharide (LPS)- induced acute lung injury (ALI) in rats and the underlying mechanisms." | 3.75 | [Role of hydrogen sulfide/cystathionine-gamma-lyase system in acute lung injury induced by lipopolysaccharide in rats]. ( Huang, XL; Ling, YL; Tian, FJ; Wei, P; Zhou, XH, 2009) |
"To explore the role of endogenous and exogenous hydrogen sulfide (H2S) in lipopolysaccharide (LPS)-induced acute lung injury (ALI) in rats and the underlying mechanisms." | 3.75 | [Role of endogenous and exogenous hydrogen sulfide in acute lung injury induced by LPS in rats]. ( Huang, XL; Ling, YL; Wei, P; Zhou, XH, 2009) |
"To explore the role of hydrogen sulfide (H2S) in acute lung injury (ALI) during endotoxic shock (ES) and its relationship with nitric oxide (NO) and carbon monoxide (CO)." | 3.74 | [The role of hydrogen sulfide in acute lung injury during endotoxic shock and its relationship with nitric oxide and carbon monoxide]. ( Huang, XL; Ling, YL; Wei, P; Xian, XH; Zhou, XH, 2008) |
"To investigate the effects of carbon monoxide (CO) inhalation on the apoptosis of pulmonary cells in rats with acute lung injury (ALI) induced by lipopolysaccharide (LPS) and to investigate its mechanisms." | 3.73 | [The mechanisms of carbon monoxide inhalation on the apoptosis of pulmonary cells in rats with acute lung injury induced by lipopolysaccharide]. ( Liu, SH; Ma, K; Xu, B; Xu, XR, 2006) |
"Transfusion-related acute lung injury is the leading cause of transfusion-related mortality." | 2.82 | Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans. ( Bonta, PI; Cortjens, B; de Korte, D; Jonkers, RE; Juffermans, NP; Lutter, R; Peters, AL; Tuip-de Boer, AM; van Bruggen, R; van Hezel, ME; Vlaar, AP; Zeerleder, SS, 2016) |
"Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) remain major causes of morbidity and mortality in critical care medicine despite advances in therapeutic modalities." | 2.46 | Heme oxygenase-1/carbon monoxide: novel therapeutic strategies in critical care medicine. ( Choi, AM; Ryter, SW, 2010) |
"Inhaled carbon monoxide (CO) gas has therapeutic potential for patients with acute respiratory distress syndrome if a safe, evidence-based dosing strategy and a ventilator-compatible CO delivery system can be developed." | 1.42 | Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia. ( Baron, RM; Choi, AM; Davies, JD; Fredenburgh, LE; Harris, RS; Hess, DR; Kraft, BD; Piantadosi, CA; Roggli, VL; Stenzler, A; Suliman, HB; Thompson, BT; Welty-Wolf, KE; Winkler, T; Wolf, MA, 2015) |
"Even after successful resuscitation, hemorrhagic shock frequently causes pulmonary inflammation that induces acute lung injury (ALI)." | 1.39 | Inhalation of carbon monoxide following resuscitation ameliorates hemorrhagic shock-induced lung injury. ( Kawanishi, S; Maeda, S; Matsumi, M; Morimatsu, H; Morita, K; Nakao, A; Omori, E; Sato, K; Shimizu, H; Takahashi, T, 2013) |
"Up to 60% of the mice showed dyspnea, airway obstruction and hypoxemia and died between days 7 and 12 post-infection." | 1.36 | VEGF promotes malaria-associated acute lung injury in mice. ( Ataíde, R; Campos, MG; Carapau, D; Costa-Silva, A; Dias, S; Epiphanio, S; Félix, N; Marinho, CR; Monteiro, CA; Mota, MM; Pamplona, A; Pena, AC, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 8 (26.67) | 29.6817 |
2010's | 21 (70.00) | 24.3611 |
2020's | 1 (3.33) | 2.80 |
Authors | Studies |
---|---|
Xu, W | 2 |
Huang, X | 1 |
Li, W | 3 |
Qian, G | 1 |
Zhou, B | 1 |
Wang, X | 1 |
Wang, H | 1 |
Wu, F | 1 |
Chen, L | 1 |
Li, Q | 1 |
Ma, J | 1 |
Li, M | 1 |
Shi, Y | 1 |
Zazzeron, L | 1 |
Fischbach, A | 1 |
Franco, W | 1 |
Farinelli, WA | 1 |
Ichinose, F | 1 |
Bloch, DB | 1 |
Anderson, RR | 1 |
Zapol, WM | 1 |
Pereira, MLM | 1 |
Marinho, CRF | 1 |
Epiphanio, S | 2 |
Ryter, SW | 4 |
Choi, AM | 6 |
Jiang, L | 1 |
Zhao, M | 1 |
Kang, K | 1 |
Shinohara, M | 1 |
Kibi, M | 1 |
Riley, IR | 1 |
Chiang, N | 1 |
Dalli, J | 1 |
Kraft, BD | 2 |
Piantadosi, CA | 2 |
Serhan, CN | 1 |
Fredenburgh, LE | 1 |
Hess, DR | 1 |
Harris, RS | 1 |
Wolf, MA | 1 |
Suliman, HB | 1 |
Roggli, VL | 1 |
Davies, JD | 1 |
Winkler, T | 1 |
Stenzler, A | 1 |
Baron, RM | 1 |
Thompson, BT | 1 |
Welty-Wolf, KE | 1 |
Joe, Y | 1 |
Kim, SK | 1 |
Chen, Y | 1 |
Yang, JW | 1 |
Lee, JH | 1 |
Cho, GJ | 1 |
Park, JW | 1 |
Chung, HT | 1 |
Crocker, GH | 1 |
Jones, JH | 1 |
Peters, AL | 1 |
van Hezel, ME | 1 |
Cortjens, B | 1 |
Tuip-de Boer, AM | 1 |
van Bruggen, R | 1 |
de Korte, D | 1 |
Jonkers, RE | 1 |
Bonta, PI | 1 |
Zeerleder, SS | 1 |
Lutter, R | 1 |
Juffermans, NP | 1 |
Vlaar, AP | 1 |
Yu, J | 1 |
Shi, J | 1 |
Wang, D | 1 |
Dong, S | 1 |
Zhang, Y | 1 |
Wang, M | 1 |
Gong, L | 1 |
Fu, Q | 1 |
Liu, D | 1 |
Huang, XL | 3 |
Zhou, XH | 3 |
Wei, P | 3 |
Xian, XH | 1 |
Ling, YL | 3 |
Althaus, M | 1 |
Fronius, M | 1 |
Buchäckert, Y | 1 |
Vadász, I | 1 |
Clauss, WG | 1 |
Seeger, W | 1 |
Motterlini, R | 1 |
Morty, RE | 1 |
Hoetzel, A | 2 |
Schmidt, R | 1 |
Vallbracht, S | 1 |
Goebel, U | 3 |
Dolinay, T | 1 |
Kim, HP | 1 |
Ifedigbo, E | 1 |
Clemens, MG | 1 |
Tian, FJ | 1 |
Mecklenburg, A | 1 |
Siepe, M | 1 |
Roesslein, M | 1 |
Schwer, CI | 1 |
Pahl, HL | 1 |
Priebe, HJ | 1 |
Schlensak, C | 2 |
Loop, T | 2 |
Pang, Q | 1 |
Dou, L | 1 |
Pan, X | 1 |
Zeng, S | 1 |
He, J | 1 |
Zeng, Y | 1 |
Campos, MG | 1 |
Pamplona, A | 2 |
Carapau, D | 1 |
Pena, AC | 2 |
Ataíde, R | 1 |
Monteiro, CA | 1 |
Félix, N | 1 |
Costa-Silva, A | 1 |
Marinho, CR | 1 |
Dias, S | 1 |
Mota, MM | 2 |
Kanagawa, F | 1 |
Takahashi, T | 2 |
Inoue, K | 1 |
Shimizu, H | 2 |
Omori, E | 2 |
Morimatsu, H | 2 |
Maeda, S | 2 |
Katayama, H | 1 |
Nakao, A | 2 |
Morita, K | 2 |
Zhou, H | 1 |
Liu, J | 1 |
Pan, P | 1 |
Jin, D | 1 |
Ding, W | 1 |
Penacho, N | 1 |
Mancio-Silva, L | 1 |
Neres, R | 1 |
Seixas, JD | 1 |
Fernandes, AC | 1 |
Romão, CC | 1 |
Bernardes, GJ | 1 |
Faller, S | 1 |
Kawanishi, S | 1 |
Sato, K | 1 |
Matsumi, M | 1 |
Liu, SH | 1 |
Ma, K | 1 |
Xu, B | 1 |
Xu, XR | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Phase Ib Trial of Inhaled Carbon Monoxide for the Treatment of Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)[NCT04870125] | Phase 1 | 36 participants (Anticipated) | Interventional | 2023-12-06 | Recruiting | ||
A Phase II Trial of Inhaled Carbon Monoxide for the Treatment of Acute Respiratory Distress Syndrome (ARDS)[NCT03799874] | Phase 2 | 32 participants (Anticipated) | Interventional | 2019-07-01 | Active, not recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
7 reviews available for carbon monoxide and Acute Lung Injury
Article | Year |
---|---|
Could Heme Oxygenase-1 Be a New Target for Therapeutic Intervention in Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome?
Topics: Acute Lung Injury; Animals; Capillary Permeability; Carbon Monoxide; Cytokines; Disease Models, Anim | 2018 |
Carbon monoxide in exhaled breath testing and therapeutics.
Topics: Acute Lung Injury; Anesthesia; Animals; Asthma; Biomarkers; Breath Tests; Carbon Monoxide; Cystic Fi | 2013 |
Gaseous therapeutics in acute lung injury.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Carbon Monoxide; Disease Models, Animal; Hum | 2011 |
[Research progress of carbon monoxide in acute lung injury].
Topics: Acute Lung Injury; Carbon Monoxide; Humans | 2014 |
Heme oxygenase-1/carbon monoxide: novel therapeutic strategies in critical care medicine.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Drug Design; E | 2010 |
Carbon monoxide in acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Carbon Monoxide; Humans; Hyperoxia; Lung Trans | 2012 |
Cytoprotection by inhaled carbon monoxide before cardiopulmonary bypass in preclinical models.
Topics: Acute Kidney Injury; Acute Lung Injury; Administration, Inhalation; Animals; Carbon Monoxide; Cardio | 2012 |
2 trials available for carbon monoxide and Acute Lung Injury
Article | Year |
---|---|
Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1.
Topics: Acute Lung Injury; Animals; Antimetabolites; Carbon Monoxide; Cell Communication; Docosahexaenoic Ac | 2014 |
Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans.
Topics: Acute Lung Injury; Adult; Blood Preservation; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Endotox | 2016 |
21 other studies available for carbon monoxide and Acute Lung Injury
Article | Year |
---|---|
Carbon monoxide ameliorates lipopolysaccharide-induced acute lung injury via inhibition of alveolar macrophage pyroptosis.
Topics: Acute Lung Injury; Animals; Carbon Monoxide; Caspases; Lipopolysaccharides; Macrophages, Alveolar; M | 2023 |
Carbon Monoxide Attenuates Lipopolysaccharides (LPS)-Induced Acute Lung Injury in Neonatal Rats via Downregulation of Cx43 to Reduce Necroptosis.
Topics: Acute Lung Injury; Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Connexi | 2019 |
Phototherapy and extracorporeal membrane oxygenation facilitate removal of carbon monoxide in rats.
Topics: Acute Lung Injury; Animals; Carbon Monoxide; Carbon Monoxide Poisoning; Extracorporeal Membrane Oxyg | 2019 |
Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Anti-Bacterial Agents; Antioxidants; Carbon | 2015 |
Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Anti-Bacterial Agents; Antioxidants; Carbon | 2015 |
Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Anti-Bacterial Agents; Antioxidants; Carbon | 2015 |
Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Anti-Bacterial Agents; Antioxidants; Carbon | 2015 |
Tristetraprolin mediates anti-inflammatory effects of carbon monoxide on lipopolysaccharide-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Carbon Monoxide; Cytokines; Female; Gene Expre | 2015 |
Interactive effects of hypoxia, carbon monoxide and acute lung injury on oxygen transport and aerobic capacity.
Topics: Acute Lung Injury; Animals; Carbon Monoxide; Goats; Hypoxia; Male; Orchiectomy; Oxygen; Pulmonary Ga | 2016 |
Heme Oxygenase-1/Carbon Monoxide-regulated Mitochondrial Dynamic Equilibrium Contributes to the Attenuation of Endotoxin-induced Acute Lung Injury in Rats and in Lipopolysaccharide-activated Macrophages.
Topics: Acute Lung Injury; Animals; Carbon Monoxide; Disease Models, Animal; Endotoxins; Heme Oxygenase-1; L | 2016 |
[The role of hydrogen sulfide in acute lung injury during endotoxic shock and its relationship with nitric oxide and carbon monoxide].
Topics: Acute Lung Injury; Animals; Blood Pressure; Carbon Monoxide; Cystathionine gamma-Lyase; Heme Oxygena | 2008 |
Carbon monoxide rapidly impairs alveolar fluid clearance by inhibiting epithelial sodium channels.
Topics: Acute Lung Injury; Amiloride; Animals; Body Fluids; Boranes; Carbon Monoxide; Carbonates; Cell Line; | 2009 |
Carbon monoxide prevents ventilator-induced lung injury via caveolin-1.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Carbon Monoxide; C | 2009 |
What's new in Shock, May 2009?
Topics: Acute Lung Injury; Animals; Carbon Monoxide; Humans; Sepsis; Shock | 2009 |
[Role of hydrogen sulfide/cystathionine-gamma-lyase system in acute lung injury induced by lipopolysaccharide in rats].
Topics: Acute Lung Injury; Animals; Carbon Monoxide; Cystathionine gamma-Lyase; Disease Models, Animal; Heme | 2009 |
Protective effects of inhaled carbon monoxide in pig lungs during cardiopulmonary bypass are mediated via an induction of the heat shock response.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Antioxidants; Carbon Monoxide; Cardiopulmona | 2009 |
Methylene chloride protects against cecal ligation and puncture-induced acute lung injury by modulating inflammatory mediators.
Topics: Acute Lung Injury; Animals; Carbon Monoxide; Cecum; Cytoprotection; Disease Models, Animal; Disulfir | 2010 |
VEGF promotes malaria-associated acute lung injury in mice.
Topics: Acute Lung Injury; Airway Obstruction; Animals; Anti-Inflammatory Agents; Carbon Monoxide; Disease M | 2010 |
Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Carbon Monoxide; Carboxyhemoglobin; Disease | 2010 |
Carbon monoxide inhalation decreased lung injury via anti-inflammatory and anti-apoptotic effects in brain death rats.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Apoptosis; Brain Death; Carbon Monoxide; Cas | 2010 |
[Role of endogenous and exogenous hydrogen sulfide in acute lung injury induced by LPS in rats].
Topics: Acute Lung Injury; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Heme Oxygen | 2009 |
A novel carbon monoxide-releasing molecule fully protects mice from severe malaria.
Topics: Acute Lung Injury; Animals; Antimalarials; Carbon Monoxide; Carboxyhemoglobin; Gene Expression Regul | 2012 |
Inhalation of carbon monoxide following resuscitation ameliorates hemorrhagic shock-induced lung injury.
Topics: Acute Lung Injury; Animals; Apoptosis; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; G | 2013 |
[The mechanisms of carbon monoxide inhalation on the apoptosis of pulmonary cells in rats with acute lung injury induced by lipopolysaccharide].
Topics: Acute Lung Injury; Animals; Apoptosis; Carbon Monoxide; Heme Oxygenase-1; Lipopolysaccharides; Lung; | 2006 |