Page last updated: 2024-09-03

carbene and Neoplasms

carbene has been researched along with Neoplasms in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's19 (61.29)24.3611
2020's12 (38.71)2.80

Authors

AuthorsStudies
Cabezas-Sainz, P; Cordeiro, S; Fernandes, AR; Fernández Vila, S; Fernández, JAA; Horta-Meireles, M; Lenis-Rojas, OA; Royo, B; Rubiolo, JA; Sanchez, L1
Bhandary, S; Canzonieri, V; Cavarzerani, E; Cazin, CSJ; Gobbo, A; Nolan, SP; Rizzolio, F; Scattolin, T; Tzouras, NV; Van Hecke, K; Vougioukalakis, GC1
Abramova, O; Diachkova, E; Grin, M; Morozova, N; Pankratov, A; Plotnikova, E; Plutinskaya, A; Tikhonov, S; Vasil'ev, Y1
Chen, C; Lv, H; Shen, C; Xu, H; Zhu, D1
Bijani, C; Cuvillier, O; Deraeve, C; Gornitzka, H; Hemmert, C; Maddelein, ML; Madji, R; Mazères, S; Voros, C; Wang, X; Zhang, C1
Burton, AJ; Kleiner, RE; Lee, G; MacMillan, DWC; Muir, TW; Seath, CP; Sun, X1
da Silva Dos Reis Condé, CA; de Andrade Querino, AL; Navarro, M; Silva, H1
Cameron, CG; Colón, KL; Jabed, MA; Kilina, S; Liu, B; McFarland, SA; Monro, S; Sun, W; Xu, W1
Fay, R; Guillou, A; Gut, M; Holland, JP; Klingler, S1
Aikman, B; Bonsignore, R; Casini, A; Coles, SJ; Döllerer, D; Klooster, WT; Luk, L; Meier-Menches, SM; Santi, N1
Achard, T; Bellemin-Laponnaz, S; Bouché, M; Vincent, B1
Aguilar, I; Arambula, JF; Arumugam, K; Cui, Z; DeVore, JE; Hufnagel, S; Lynch, VM; Maier, EY; Selvakumar, J; Sen, S; Sessler, JL1
Cantürk-Kılıçkaya, P; Kılıçkaya, O; Şahin-Bölükbaşı, S1
Casini, A; Karaca, Ö; Kühn, FE; Meier-Menches, SM1
Casini, A; de Graaf, IAM; de Jager, MH; Estrada-Ortiz, N; Gabbiani, C; Groothuis, GMM; Guarra, F; Marchetti, L1
Balusu, R; Björkling, F; Kankala, S; Taylor, MK; Thota, N; Vadde, R1
Gimeno, MC; Mora, M; Visbal, R1
Coles, SJ; Groves, LM; Hayes, AJ; Horton, PN; Isaacs, MD; Lloyd, D; Pope, SJA; Symonds, NO; Ward, BD; Williams, CF1
Choi, W; Kang, Y; Kim, C; Kim, J; Kim, K; Kim, WJ; Lee, E; Lee, YM; Park, J; Park, KM; Saravanakumar, G1
Bindoli, A; Casini, A; Citta, A; Folda, A; Massimino, ML; Mohr, F; Rigobello, MP; Schuh, E1
Dolmella, A; Gandin, V; Giorgetti, M; Marinelli, M; Marzano, C; Pellei, M; Santini, C1
Bertrand, B; Casini, A1
Deng, L; Hu, C; Li, X; Wang, W; Zhang, R1
Alborzinia, H; Can, S; Cheng, X; Holenya, P; Jünger, A; Ott, I; Rubbiani, R; Wölfl, S1
Balakrishna, GR; Budagumpi, S; Keri, RS; Patil, R; Patil, SA; Tacke, M1
Cao, B; Che, CM; Chen, T; Fung, SK; Lok, CN; To, WP; Yang, C; Zou, T1
Che, CM; Chow, PK; Chung, CY; Fong, TT; Fung, YM; Lok, CN; Wan, PK1
Alves, G; Avignant, D; Cisnetti, F; El-Ghozzi, M; Gautier, A; Legeret, B; Morel, L; Nauton, L1
Cisnetti, F; Gautier, A1
Biersack, B; Kaps, L; Mahal, K; Mueller, T; Müller-Bunz, H; Münzner, J; Schobert, R; Tacke, M1
Gust, R; Liu, W1

Reviews

9 review(s) available for carbene and Neoplasms

ArticleYear
Silver(I)-N-heterocyclic carbene complexes challenge cancer; evaluation of their anticancer properties and in silico studies.
    Drug development research, 2021, Volume: 82, Issue:7

    Topics: Heterocyclic Compounds; Methane; Neoplasms; Silver; Structure-Activity Relationship

2021
On the binding modes of metal NHC complexes with DNA secondary structures: implications for therapy and imaging.
    Chemical communications (Cambridge, England), 2017, Jul-20, Volume: 53, Issue:59

    Topics: Animals; Antineoplastic Agents; Binding Sites; DNA, Neoplasm; Heterocyclic Compounds; Humans; Metals; Methane; Molecular Imaging; Neoplasms; Nucleic Acid Conformation; Organometallic Compounds

2017
Silver carbene complexes: An emerging class of anticancer agents.
    Drug development research, 2019, Volume: 80, Issue:2

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Humans; Methane; Neoplasms; Silver

2019
Recent advances in gold-NHC complexes with biological properties.
    Chemical Society reviews, 2019, Jan-21, Volume: 48, Issue:2

    Topics: Antioxidants; Apoptosis; Coordination Complexes; Gold; Gram-Negative Bacteria; Gram-Positive Bacteria; Heterocyclic Compounds; Humans; Methane; Neoplasms

2019
A golden future in medicinal inorganic chemistry: the promise of anticancer gold organometallic compounds.
    Dalton transactions (Cambridge, England : 2003), 2014, Mar-21, Volume: 43, Issue:11

    Topics: Alkynes; Animals; Antineoplastic Agents; Humans; Methane; Neoplasms; Organogold Compounds

2014
Metal-N-heterocyclic carbene complexes as anti-tumor agents.
    Current medicinal chemistry, 2014, Volume: 21, Issue:10

    Topics: Antineoplastic Agents; Auranofin; Cell Line, Tumor; Cisplatin; Coordination Complexes; Copper; Gold; Heterocyclic Compounds; Humans; Methane; Neoplasms; Palladium; Platinum; Silver; Structure-Activity Relationship

2014
N-heterocyclic carbene metal complexes as bio-organometallic antimicrobial and anticancer drugs.
    Future medicinal chemistry, 2015, Volume: 7, Issue:10

    Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Coordination Complexes; Heterocyclic Compounds; Humans; Metals; Methane; Neoplasms

2015
Advances in metal-carbene complexes as potent anti-cancer agents.
    Metallomics : integrated biometal science, 2012, Volume: 4, Issue:1

    Topics: Antineoplastic Agents; Cell Line; Coordination Complexes; Heterocyclic Compounds; Humans; Metals; Methane; Molecular Structure; Neoplasms

2012
Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs.
    Chemical Society reviews, 2013, Jan-21, Volume: 42, Issue:2

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Humans; Methane; Models, Molecular; Neoplasms; Transition Elements

2013

Other Studies

22 other study(ies) available for carbene and Neoplasms

ArticleYear
    Molecules (Basel, Switzerland), 2021, Sep-12, Volume: 26, Issue:18

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Screening Assays, Antitumor; Fibroblasts; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Iron Compounds; Methane; Neoplasms; Xenograft Model Antitumor Assays; Zebrafish

2021
A Green Synthesis of Carbene-Metal-Amides (CMAs) and Carboline-Derived CMAs with Potent in vitro and ex vivo Anticancer Activity.
    ChemMedChem, 2022, 07-05, Volume: 17, Issue:13

    Topics: Amides; Carbolines; Heterocyclic Compounds; Humans; Ligands; Metals; Methane; Molecular Structure; Neoplasms

2022
    International journal of molecular sciences, 2022, Dec-12, Volume: 23, Issue:24

    Topics: Cell Line, Tumor; Coordination Complexes; Gold; Histamine; Histidine; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents

2022
Cyclometalated Ru(II)-NHC complexes with phenanthroline ligands induce apoptosis mediated by mitochondria and endoplasmic reticulum stress in cancer cells.
    Dalton transactions (Cambridge, England : 2003), 2023, Feb-07, Volume: 52, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Coordination Complexes; Endoplasmic Reticulum Stress; HeLa Cells; Humans; Ligands; Mitochondria; Neoplasms; Phenanthrolines; Ruthenium

2023
    Molecules (Basel, Switzerland), 2023, Jan-10, Volume: 28, Issue:2

    Topics: Apoptosis; Cell Line, Tumor; Humans; Iridium; Neoplasms; Photochemotherapy; Photosensitizing Agents

2023
Tracking chromatin state changes using nanoscale photo-proximity labelling.
    Nature, 2023, Volume: 616, Issue:7957

    Topics: Cell Nucleus; Chromatin; Cross-Linking Reagents; Energy Transfer; Epigenomics; Humans; Inteins; Iridium; Mutation; Neoplasms; Photosensitizing Agents; Protein Binding; Protein Interaction Maps

2023
Silver(I) complexes containing N-heterocyclic carbene azole drugs: Synthesis, characterization, cytotoxic activity, and their BSA interactions.
    Journal of inorganic biochemistry, 2023, Volume: 246

    Topics: Animals; Antineoplastic Agents; Azoles; Clotrimazole; Coordination Complexes; Humans; Ketoconazole; Ligands; Mice; Neoplasms; Pharmaceutical Preparations; Silver

2023
Neutral iridium(iii) complexes bearing BODIPY-substituted N-heterocyclic carbene (NHC) ligands: synthesis, photophysics, in vitro theranostic photodynamic therapy, and antimicrobial activity.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2019, Oct-09, Volume: 18, Issue:10

    Topics: Anti-Infective Agents; Boron Compounds; Cell Line, Tumor; Cell Survival; Coordination Complexes; Humans; Iridium; Ligands; Light; Methane; Neoplasms; Photochemotherapy; Photosensitizing Agents; Quantum Theory; Reactive Oxygen Species; Staphylococcus aureus; Theranostic Nanomedicine

2019
Photochemical Reactions in the Synthesis of Protein-Drug Conjugates.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Jan-02, Volume: 26, Issue:1

    Topics: Animals; Antibodies; Cell Line, Tumor; Copper Radioisotopes; Cycloaddition Reaction; Humans; Isotope Labeling; Ligands; Methane; Mice; Mice, Nude; Neoplasms; Pharmaceutical Preparations; Proteins; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous; Ultraviolet Rays

2020
Comparative biological evaluation and G-quadruplex interaction studies of two new families of organometallic gold(I) complexes featuring N-heterocyclic carbene and alkynyl ligands.
    Journal of inorganic biochemistry, 2020, Volume: 202

    Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; G-Quadruplexes; Humans; Ligands; MCF-7 Cells; Methane; Neoplasms; Organogold Compounds

2020
    Molecules (Basel, Switzerland), 2020, Jul-09, Volume: 25, Issue:14

    Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Methane; Neoplasms; Nuclear Magnetic Resonance, Biomolecular; Organoplatinum Compounds; PC-3 Cells

2020
Rationally Designed Redox-Active Au(I) N-Heterocyclic Carbene: An Immunogenic Cell Death Inducer.
    Journal of the American Chemical Society, 2020, 12-09, Volume: 142, Issue:49

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Endoplasmic Reticulum Stress; Gold; Heterocyclic Compounds; Humans; Immunogenic Cell Death; Methane; Mice; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Transplantation, Heterologous

2020
Anticancer Gold N-Heterocyclic Carbene Complexes: A Comparative in vitro and ex vivo Study.
    ChemMedChem, 2017, 09-07, Volume: 12, Issue:17

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Heterocyclic Compounds; Humans; Kidney; Male; Methane; Neoplasms; Organogold Compounds; Rats, Wistar

2017
Fluorescent functionalised naphthalimides and their Au(i)-NHC complexes for potential use in cellular bioimaging.
    Dalton transactions (Cambridge, England : 2003), 2019, Feb-07, Volume: 48, Issue:5

    Topics: Cell Proliferation; Coordination Complexes; Crystallography, X-Ray; Fluorescent Dyes; Gold; Heterocyclic Compounds; Humans; Ligands; Methane; Models, Molecular; Molecular Structure; Naphthalimides; Neoplasms; Tumor Cells, Cultured

2019
Tumor vasodilation by N-Heterocyclic carbene-based nitric oxide delivery triggered by high-intensity focused ultrasound and enhanced drug homing to tumor sites for anti-cancer therapy.
    Biomaterials, 2019, Volume: 217

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Chickens; Doxorubicin; Drug Delivery Systems; Drug Liberation; Female; Heterocyclic Compounds; High-Intensity Focused Ultrasound Ablation; Methane; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Nitric Oxide; Temperature; Tissue Distribution; Vasodilation

2019
Fluorescent silver(I) and gold(I)-N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights.
    Metallomics : integrated biometal science, 2013, Volume: 5, Issue:8

    Topics: Animals; Cell Line, Tumor; Cell Survival; Cytosol; Dimerization; Drug Screening Assays, Antitumor; Glutathione Reductase; Gold; Humans; Liver; Methane; Microscopy, Fluorescence; Mitochondria; Neoplasms; Oxidation-Reduction; Peroxiredoxin III; Rats; Reactive Oxygen Species; Silver; Thioredoxin-Disulfide Reductase

2013
Synthesis and in vitro antitumor activity of water soluble sulfonate- and ester-functionalized silver(I) N-heterocyclic carbene complexes.
    Journal of inorganic biochemistry, 2013, Volume: 129

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Heterocyclic Compounds, 1-Ring; Humans; MAP Kinase Kinase Kinase 5; Methane; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Selenoproteins; Signal Transduction; Silver; Solubility; Thioredoxin-Disulfide Reductase; Water

2013
Detailed analysis of pro-apoptotic signaling and metabolic adaptation triggered by a N-heterocyclic carbene-gold(I) complex.
    Metallomics : integrated biometal science, 2014, Volume: 6, Issue:9

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Gold; Heterocyclic Compounds; Humans; Intracellular Space; Methane; Mice; Mitochondria; Models, Biological; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Thioredoxin-Disulfide Reductase

2014
Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA.
    Nature communications, 2016, Feb-17, Volume: 7

    Topics: Base Pair Mismatch; Biosensing Techniques; DNA; Humans; Luminescence; Methane; Neoplasms; Platinum

2016
Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression.
    Angewandte Chemie (International ed. in English), 2016, 09-19, Volume: 55, Issue:39

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coordination Complexes; Humans; Methane; Mice, Nude; Neoplasms; Palladium

2016
A platinum Chugaev carbene complex as a potent anticancer agent.
    Chemical communications (Cambridge, England), 2011, Jul-21, Volume: 47, Issue:27

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; DNA, Superhelical; Humans; Magnetic Resonance Spectroscopy; Methane; Models, Molecular; Neoplasms; Organoplatinum Compounds; Stereoisomerism; Sulfhydryl Compounds

2011
Gold(I)-NHC complexes of antitumoral diarylimidazoles: structures, cellular uptake routes and anticancer activities.
    Journal of inorganic biochemistry, 2012, Volume: 106, Issue:1

    Topics: Antineoplastic Agents; Cation Transport Proteins; Cell Line, Tumor; Cell Survival; Cells, Cultured; Copper Transport Proteins; Crystallography, X-Ray; Fibroblasts; Gold; Heterocyclic Compounds; HL-60 Cells; HT29 Cells; Humans; Imidazoles; Metallochaperones; Methane; Models, Molecular; Molecular Chaperones; Molecular Structure; Neoplasms; Organic Cation Transport Proteins; Organometallic Compounds; Tubulin

2012