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carbazilquinone and Sarcoma 180

carbazilquinone has been researched along with Sarcoma 180 in 5 studies

Carbazilquinone: An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.

Sarcoma 180: An experimental sarcoma of mice.

Research Excerpts

ExcerptRelevanceReference
"Enhancement of the cytotoxicity of mitomycin C (MMC) and carboquone (CQ) by hypoxia at elevated temperature was examined using the SDI test of mouse Sarcoma 180 and Ehrlich cells and clonogenic assay of HeLa cells."3.68Cytotoxicity of mitomycin C and carboquone combined with hyperthermia against hypoxic tumor cells in vitro. ( Emi, Y; Kohnoe, S; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K, 1992)
"The effects of oxygen concentration on the chemosensitivity of mouse sarcoma-180 (S-180) cells and human colorectal cancer tissues to mitomycin C (MMC) or carboquone (CQ) were determined in vitro, since evidence had been obtained that these drugs are more effective in HeLa cells."3.68Sarcoma-180 cells and human colorectal tumor cells under in vitro hypoxic conditions are more sensitive to mitomycin C and carboquone. ( Emi, Y; Kohnoe, S; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kondo, T1
Sakamoto, J1
Ichihashi, H1
Kamei, H1
Iigo, M1
Nakamura, A1
Hoshi, A1
Kuretani, K1
Sakaguchi, Y3
Kohnoe, S2
Emi, Y3
Maehara, Y3
Kusumoto, T3
Sugimachi, K3
Anai, H1

Other Studies

5 other studies available for carbazilquinone and Sarcoma 180

ArticleYear
Effect of alternating administration of PS-K and carbazilquinone in tumor-bearing mice.
    Gan, 1981, Volume: 72, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Azirines; Carbazilquinone; Hyper

1981
Interaction of antitumor agents including carboquone in sarcoma-180 system.
    Gan, 1976, Volume: 67, Issue:5

    Topics: Animals; Antineoplastic Agents; Azirines; Carbazilquinone; Drug Interactions; Drug Therapy, Combinat

1976
Cytotoxicity of mitomycin C and carboquone combined with hyperthermia against hypoxic tumor cells in vitro.
    Oncology, 1992, Volume: 49, Issue:3

    Topics: Aerobiosis; Anaerobiosis; Animals; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone;

1992
Sarcoma-180 cells and human colorectal tumor cells under in vitro hypoxic conditions are more sensitive to mitomycin C and carboquone.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1991, Volume: 17, Issue:4

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carbazilquinone; Cell Hypoxia; Colorectal Neoplas

1991
Detection of DNA strand breaks in HeLa cells in vitro and in mouse sarcoma 180 cells in vivo induced by an alkylating agent, carboquone, using in situ nick translation.
    Oncology, 1990, Volume: 47, Issue:3

    Topics: Animals; Autoradiography; Azirines; Carbazilquinone; DNA Damage; Dose-Response Relationship, Drug; H

1990