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carbazilquinone and Polycythemia Vera

carbazilquinone has been researched along with Polycythemia Vera in 6 studies

Carbazilquinone: An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.

Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.

Research Excerpts

ExcerptRelevanceReference
"A 57-year-old male who had suffered from polycythemia vera (PV) and had been treated with pipobroman, carbazilquinon and busulfan for ten years presented with fever."4.78[Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report]. ( Hino, K; Koike, T; Sakashita, A; Sato, S; Tomoyasu, S; Tsuruoka, N, 1992)
"A 77-year-old male, who had been treated with carboquone and busulfan for polycythemia vera (PV), developed myelodysplastic syndrome (MDS) 8 years later."3.68[Polycythemia vera terminating in myelodysplastic syndrome]. ( Abe, T; Kimura, S; Kobayashi, Y; Kondo, M; Maruo, N; Ozawa, M; Tanaka, R; Uoshima, N; Yoshida, Y, 1990)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uzuka, Y1
Saito, Y1
Takahashi, H1
Komatsu, M1
Niikura, H2
Hagiwara, S1
Nishiyama, H1
Mori, H2
Mohri, H1
Matsuno, K1
Terada, H2
Higuchi, T1
Okada, S1
Omine, M1
Hino, K1
Sato, S1
Sakashita, A1
Tomoyasu, S1
Tsuruoka, N1
Koike, T1
Yagi, S1
Hashiguchi, K1
Nakajima, M1
Umeki, S1
Hara, H1
Soejima, R1
Kimura, S1
Uoshima, N1
Tanaka, R1
Kobayashi, Y1
Ozawa, M1
Maruo, N1
Kondo, M1
Abe, T1
Yoshida, Y1

Reviews

1 review available for carbazilquinone and Polycythemia Vera

ArticleYear
[Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1992, Volume: 33, Issue:4

    Topics: Blast Crisis; Busulfan; Carbazilquinone; Disseminated Intravascular Coagulation; Humans; Leukemia, M

1992

Other Studies

5 other studies available for carbazilquinone and Polycythemia Vera

ArticleYear
Carboquone therapy for hematologic neoplasms.
    The Tohoku journal of experimental medicine, 1982, Volume: 138, Issue:2

    Topics: Administration, Oral; Adult; Aged; Azirines; Carbazilquinone; Female; Humans; Leukemia, Myeloid; Lym

1982
[Therapy of polycythemia vera and essential thrombocythemia with carboquone (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1981, Volume: 22, Issue:11

    Topics: Adult; Aged; Azirines; Carbazilquinone; Female; Humans; Male; Middle Aged; Polycythemia Vera; Thromb

1981
Leukemic transformation of polycythemia vera and essential thrombocythemia possibly associated with an alkylating agent.
    Cancer, 1995, Jan-15, Volume: 75, Issue:2

    Topics: Adult; Aged; Carbazilquinone; Chromosome Aberrations; Female; Follow-Up Studies; Humans; Leukemia, M

1995
[A case of polycythemia vera associated with idiopathic interstitial pneumonia successfully treated by alkylating agents].
    Nihon Kyobu Shikkan Gakkai zasshi, 1990, Volume: 28, Issue:10

    Topics: Alkylating Agents; Carbazilquinone; Cyclophosphamide; Female; Humans; Middle Aged; Polycythemia Vera

1990
[Polycythemia vera terminating in myelodysplastic syndrome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:1

    Topics: Aged; Busulfan; Carbazilquinone; Humans; Male; Myelodysplastic Syndromes; Polycythemia Vera

1990