carbazilquinone has been researched along with Polycythemia Vera in 6 studies
Carbazilquinone: An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.
Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 57-year-old male who had suffered from polycythemia vera (PV) and had been treated with pipobroman, carbazilquinon and busulfan for ten years presented with fever." | 4.78 | [Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report]. ( Hino, K; Koike, T; Sakashita, A; Sato, S; Tomoyasu, S; Tsuruoka, N, 1992) |
| "A 77-year-old male, who had been treated with carboquone and busulfan for polycythemia vera (PV), developed myelodysplastic syndrome (MDS) 8 years later." | 3.68 | [Polycythemia vera terminating in myelodysplastic syndrome]. ( Abe, T; Kimura, S; Kobayashi, Y; Kondo, M; Maruo, N; Ozawa, M; Tanaka, R; Uoshima, N; Yoshida, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uzuka, Y | 1 |
| Saito, Y | 1 |
| Takahashi, H | 1 |
| Komatsu, M | 1 |
| Niikura, H | 2 |
| Hagiwara, S | 1 |
| Nishiyama, H | 1 |
| Mori, H | 2 |
| Mohri, H | 1 |
| Matsuno, K | 1 |
| Terada, H | 2 |
| Higuchi, T | 1 |
| Okada, S | 1 |
| Omine, M | 1 |
| Hino, K | 1 |
| Sato, S | 1 |
| Sakashita, A | 1 |
| Tomoyasu, S | 1 |
| Tsuruoka, N | 1 |
| Koike, T | 1 |
| Yagi, S | 1 |
| Hashiguchi, K | 1 |
| Nakajima, M | 1 |
| Umeki, S | 1 |
| Hara, H | 1 |
| Soejima, R | 1 |
| Kimura, S | 1 |
| Uoshima, N | 1 |
| Tanaka, R | 1 |
| Kobayashi, Y | 1 |
| Ozawa, M | 1 |
| Maruo, N | 1 |
| Kondo, M | 1 |
| Abe, T | 1 |
| Yoshida, Y | 1 |
1 review available for carbazilquinone and Polycythemia Vera
| Article | Year |
|---|---|
[Megakaryoblastic transformation associated with disseminated intravascular coagulation in the course of polycythemia vera: a case report].
Topics: Blast Crisis; Busulfan; Carbazilquinone; Disseminated Intravascular Coagulation; Humans; Leukemia, M | 1992 |
5 other studies available for carbazilquinone and Polycythemia Vera
| Article | Year |
|---|---|
Carboquone therapy for hematologic neoplasms.
Topics: Administration, Oral; Adult; Aged; Azirines; Carbazilquinone; Female; Humans; Leukemia, Myeloid; Lym | 1982 |
[Therapy of polycythemia vera and essential thrombocythemia with carboquone (author's transl)].
Topics: Adult; Aged; Azirines; Carbazilquinone; Female; Humans; Male; Middle Aged; Polycythemia Vera; Thromb | 1981 |
Leukemic transformation of polycythemia vera and essential thrombocythemia possibly associated with an alkylating agent.
Topics: Adult; Aged; Carbazilquinone; Chromosome Aberrations; Female; Follow-Up Studies; Humans; Leukemia, M | 1995 |
[A case of polycythemia vera associated with idiopathic interstitial pneumonia successfully treated by alkylating agents].
Topics: Alkylating Agents; Carbazilquinone; Cyclophosphamide; Female; Humans; Middle Aged; Polycythemia Vera | 1990 |
[Polycythemia vera terminating in myelodysplastic syndrome].
Topics: Aged; Busulfan; Carbazilquinone; Humans; Male; Myelodysplastic Syndromes; Polycythemia Vera | 1990 |