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carbazilquinone and Liver Neoplasms

carbazilquinone has been researched along with Liver Neoplasms in 10 studies

Carbazilquinone: An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.

Liver Neoplasms: Tumors or cancer of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Mitomycin C was observed potentially to have enhanced cytotoxicity under hypoxic conditions for both hepatoma cell lines."1.28The difference in chemosensitivity to antineoplastic agents of human hepatocellular carcinoma cells under normo-oxygenated or hypoxic conditions. ( Ikeda, Y; Kanematsu, T; Matsumata, T; Sugimachi, K; Utsunomiya, T; Yamagata, M, 1992)
"A case of relapsed gastric cancer postoperatively presenting obstructive jaundice due to metastases in the hepatic portal and periaortic lymph nodes and multiple lung metastases was given OK-432 continuously i."1.27[A case of relapsed gastric cancer treated successfully by chemotherapy--lung metastasis and relapsed cancer in the hepatic portal system]. ( Kawahara, M; Matsuo, T; Nagamatsu, Y; Nakarai, I; Shinoda, A, 1986)
"Carbazilquinone was unique among others in that NADH can replace NADPH and its higher ability to initiate sulfite oxidation."1.25Generation of free radicals of quinone group-containing anti-cancer chemicals in NADPH-microsome system as evidenced by initiation of sulfite oxidation. ( Handa, K; Sato, S, 1975)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Monna, T1
Kanno, T1
Marumo, T1
Harihara, S1
Kuroki, T1
Yamamoto, S1
Kobayashi, N1
Sato, M1
Nakamura, K1
Nakatsuka, H1
Onoyama, Y1
Yamada, R1
Himori, T1
Ujiie, S1
Mimata, Y1
Sugiyama, Z1
Wakui, A1
Kojima, J1
Kamada, T1
Monna, J1
Abe, I1
Sato, S2
Kanamaru, R1
Asamura, M1
Sato, H1
Saito, T1
Handa, K1
Yamagata, M1
Kanematsu, T2
Matsumata, T1
Utsunomiya, T1
Ikeda, Y1
Sugimachi, K2
Sakata, Y1
Komatsu, Y1
Takagi, S1
Saitoh, S1
Itoh, T1
Suzuki, H1
Tsushima, K1
Sasaki, D1
Yoshida, Y1
Maehara, Y1
Kusumoto, T1
Nagamatsu, Y1
Nakarai, I1
Matsuo, T1
Kawahara, M1
Shinoda, A1

Trials

3 trials available for carbazilquinone and Liver Neoplasms

ArticleYear
A comparison of transcatheter arterial embolization with one shot therapy for the patients with hepatic cell carcinoma.
    Gastroenterologia Japonica, 1982, Volume: 17, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Carbazilquinone; Carcinoma, Hepatocellular; Catheterization; Dox

1982
[Clinical study on combination chemotherapy of primary liver cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:4 Pt 1

    Topics: Adult; Aged; Azirines; Carbazilquinone; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Co

1983
Randomized controlled study of mitomycin C/carboquone/5-fluorouracil/OK-432 (MQ-F-OK) therapy and mitomycin C/5-fluorouracil/doxorubicin (FAM) therapy against advanced liver cancer.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23 Suppl

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Clinical Trials as Top

1989

Other Studies

7 other studies available for carbazilquinone and Liver Neoplasms

ArticleYear
Total tumor cell count and hematopoietic system of ah 109A-bearing rats treated with mitomycin C and carboquone.
    The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1982, Volume: 29, Issue:1-4

    Topics: Animals; Antineoplastic Agents; Azirines; Carbazilquinone; Carcinoma, Hepatocellular; Cell Transform

1982
Beta-glucuronidase activity of Yoshida ascites hepatomas of different drug-sensitivity and its change after treatment of host rats with various anticancer agents.
    Gan, 1976, Volume: 67, Issue:1

    Topics: Animals; Antineoplastic Agents; Bleomycin; Carbazilquinone; Carcinoma, Hepatocellular; Chromomycins;

1976
Comparative studies of effects of carbazilquinone and mitomycin C on DNA, RNA and protein synthesis of Yoshida sarcoma and Yoshida ascites hepatomas.
    The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1975, Volume: 22, Issue:1-2

    Topics: Animals; Azirines; Carbazilquinone; Carcinoma, Hepatocellular; DNA, Neoplasm; Liver Neoplasms; Mitom

1975
Generation of free radicals of quinone group-containing anti-cancer chemicals in NADPH-microsome system as evidenced by initiation of sulfite oxidation.
    Gan, 1975, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Carbazilquinone; Chromomycin A3; Cyclophosphamide; Daunorubicin; Dox

1975
The difference in chemosensitivity to antineoplastic agents of human hepatocellular carcinoma cells under normo-oxygenated or hypoxic conditions.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1992, Volume: 18, Issue:4

    Topics: Antineoplastic Agents; Carbazilquinone; Carcinoma, Hepatocellular; Cell Hypoxia; Cisplatin; Doxorubi

1992
Sensitivity to six antitumor drugs differs between primary and metastatic liver cancers.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:9

    Topics: Aclarubicin; Antineoplastic Agents; Carbazilquinone; Carcinoma, Hepatocellular; Cisplatin; Doxorubic

1988
[A case of relapsed gastric cancer treated successfully by chemotherapy--lung metastasis and relapsed cancer in the hepatic portal system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Humans; Liver

1986