carbazilquinone has been researched along with Colorectal Neoplasms in 4 studies
Carbazilquinone: An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We determined the increase in antineoplastic activities of mitomycin C (MMC) and carboquone (CQ) against human tumor cells under conditions of in vitro hypoxia, with the following results." | 7.67 | Hypoxia enhances the lethality of mitomycin C and carboquone against human malignant tumor cells in vitro. ( Kusumoto, T; Maehara, Y; Sakaguchi, Y; Saku, M; Sugimachi, K, 1989) |
| "The effects of oxygen concentration on the chemosensitivity of mouse sarcoma-180 (S-180) cells and human colorectal cancer tissues to mitomycin C (MMC) or carboquone (CQ) were determined in vitro, since evidence had been obtained that these drugs are more effective in HeLa cells." | 3.68 | Sarcoma-180 cells and human colorectal tumor cells under in vitro hypoxic conditions are more sensitive to mitomycin C and carboquone. ( Emi, Y; Kohnoe, S; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K, 1991) |
| " We determined the increase in antineoplastic activities of mitomycin C (MMC) and carboquone (CQ) against human tumor cells under conditions of in vitro hypoxia, with the following results." | 3.67 | Hypoxia enhances the lethality of mitomycin C and carboquone against human malignant tumor cells in vitro. ( Kusumoto, T; Maehara, Y; Sakaguchi, Y; Saku, M; Sugimachi, K, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kusumoto, T | 3 |
| Maehara, Y | 3 |
| Sakaguchi, Y | 2 |
| Kohnoe, S | 1 |
| Emi, Y | 1 |
| Sugimachi, K | 3 |
| Nio, Y | 1 |
| Imai, S | 1 |
| Shiraishi, T | 1 |
| Tsubono, M | 1 |
| Morimoto, H | 1 |
| Tseng, CC | 1 |
| Tobe, T | 1 |
| Saku, M | 1 |
| Kusumoto, H | 1 |
| Anai, H | 1 |
4 other studies available for carbazilquinone and Colorectal Neoplasms
| Article | Year |
|---|---|
Sarcoma-180 cells and human colorectal tumor cells under in vitro hypoxic conditions are more sensitive to mitomycin C and carboquone.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carbazilquinone; Cell Hypoxia; Colorectal Neoplas | 1991 |
Chemosensitivity correlation between the primary tumors and simultaneous metastatic lymph nodes of patients evaluated by DNA synthesis inhibition assay.
Topics: Breast Neoplasms; Carbazilquinone; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Doxorubicin; Drug | 1990 |
Hypoxia enhances the lethality of mitomycin C and carboquone against human malignant tumor cells in vitro.
Topics: Azirines; Carbazilquinone; Carcinoma; Cells, Cultured; Colorectal Neoplasms; HeLa Cells; Humans; Hyp | 1989 |
Tumor tissue is more sensitive to mitomycin C, carboquone, and aclacinomycin A than is adjacent normal tissue in vitro.
Topics: Aclarubicin; Azirines; Carbazilquinone; Cell Survival; Colorectal Neoplasms; Drug Screening Assays, | 1989 |