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carbazilquinone and Carcinoma, Anaplastic

carbazilquinone has been researched along with Carcinoma, Anaplastic in 4 studies

Carbazilquinone: An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.

Research Excerpts

ExcerptRelevanceReference
" We determined the increase in antineoplastic activities of mitomycin C (MMC) and carboquone (CQ) against human tumor cells under conditions of in vitro hypoxia, with the following results."7.67Hypoxia enhances the lethality of mitomycin C and carboquone against human malignant tumor cells in vitro. ( Kusumoto, T; Maehara, Y; Sakaguchi, Y; Saku, M; Sugimachi, K, 1989)
"In 62 human gastric carcinomas, the expression of GST pi was immunohistochemically evaluated, and sensitivity to the anticancer drugs, cisplatin (CDDP), doxorubicin (DXR) aclacinomycin A (aclarubicin), (ACR), 5-fluorouracil (5-FU), mitomycin C (MMC) and carboquone (carbazilquinon) (CQ) was examined using the in vitro succinate dehydrogenase inhibition test."3.69Expression of glutathione S-transferase-pi and sensitivity of human gastric cancer cells to cisplatin. ( Adachi, Y; Baba, H; Endo, K; Kuwano, M; Maehara, Y; Okuyama, T; Sugimachi, K, 1994)
" We determined the increase in antineoplastic activities of mitomycin C (MMC) and carboquone (CQ) against human tumor cells under conditions of in vitro hypoxia, with the following results."3.67Hypoxia enhances the lethality of mitomycin C and carboquone against human malignant tumor cells in vitro. ( Kusumoto, T; Maehara, Y; Sakaguchi, Y; Saku, M; Sugimachi, K, 1989)
"The Kuramochi cell line, derived from undifferentiated carcinoma, was less sensitive to Mitomycin C than the groups of gastric cancer cell line."1.26[Quantitative analysis on in vitro drug sensitivity of cultured human ovarian cancer cell lines (author's transl)]. ( Motoyama, T, 1982)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Motoyama, T1
Okuyama, T1
Maehara, Y2
Endo, K1
Baba, H1
Adachi, Y1
Kuwano, M1
Sugimachi, K2
Kusumoto, T1
Sakaguchi, Y1
Saku, M1
Sugawa, T1
Yamagata, S1

Other Studies

4 other studies available for carbazilquinone and Carcinoma, Anaplastic

ArticleYear
[Quantitative analysis on in vitro drug sensitivity of cultured human ovarian cancer cell lines (author's transl)].
    Nihon Sanka Fujinka Gakkai zasshi, 1982, Volume: 34, Issue:3

    Topics: Azirines; Carbazilquinone; Carcinoma; Cell Line; Cell Survival; Cystadenocarcinoma; Dose-Response Re

1982
Expression of glutathione S-transferase-pi and sensitivity of human gastric cancer cells to cisplatin.
    Cancer, 1994, Aug-15, Volume: 74, Issue:4

    Topics: Aclarubicin; Animals; Carbazilquinone; Carcinoma; Cell Nucleus; CHO Cells; Cisplatin; Cricetinae; Cy

1994
Hypoxia enhances the lethality of mitomycin C and carboquone against human malignant tumor cells in vitro.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1989, Volume: 21, Issue:3-4

    Topics: Azirines; Carbazilquinone; Carcinoma; Cells, Cultured; Colorectal Neoplasms; HeLa Cells; Humans; Hyp

1989
[Differing progress patterns in cancer of the uterine cervix and variant effects of adjuvant chemotherapy based on histological type].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:2

    Topics: Adenocarcinoma; Azirines; Carbazilquinone; Carcinoma; Carcinoma, Squamous Cell; Female; Humans; Lymp

1986