Page last updated: 2024-11-04

carbamylhydrazine and Obesity

carbamylhydrazine has been researched along with Obesity in 5 studies

carbamylhydrazine: RN given refers to parent cpd

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Inhibition of semicarbazide-sensitive amine oxidases (SSAO) and monoamine oxidases (MAO) reduces fat deposition in obese rodents: chronic administration of the SSAO-inhibitor semicarbazide (S) in combination with pargyline (MAO-inhibitor) has been shown to reduce body weight gain in obese Zucker rats, while (E)-2-(4-fluorophenethyl)-3-fluoroallylamine, an SSAO- and MAO-B inhibitor, has been reported to limit weight gain in obese and diabetic mice."1.35Limitation of adipose tissue enlargement in rats chronically treated with semicarbazide-sensitive amine oxidase and monoamine oxidase inhibitors. ( Abello, V; Carpéné, C; Fève, B; Iffiú-Soltész, Z; Mercier, N; Valet, P, 2008)
"Obesity is associated with low-grade inflammation and leukocyte infiltration in white adipose tissue (WAT) and is linked to diabetic complications."1.35Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition. ( Bour, S; Carpéné, C; Caspar-Bauguil, S; Casteilla, L; Cousin, B; Iffiú-Soltész, Z; Jalkanen, S; Miiluniemi, M; Nibbelink, M; Pénicaud, L; Salmi, M; Stolen, C; Valet, P, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carpéné, C5
Abello, V2
Iffiú-Soltész, Z3
Mercier, N1
Fève, B1
Valet, P5
Bour, S3
Caspar-Bauguil, S1
Nibbelink, M1
Cousin, B1
Miiluniemi, M1
Salmi, M1
Stolen, C1
Jalkanen, S1
Casteilla, L1
Pénicaud, L1
Prévot, D3
Soltesz, Z1
Wanecq, E1
Unzeta, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Hematopoietic Stem Cell Activity in Adipose Tissue From Type 2 Diabetic Patients and Healthy Volunteers: Proof of Concept Study. White Adipose Tissue and Type 2 Diabetes Onset: WAT2DO[NCT03260452]20 participants (Actual)Interventional2018-06-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for carbamylhydrazine and Obesity

ArticleYear
Limitation of adipose tissue enlargement in rats chronically treated with semicarbazide-sensitive amine oxidase and monoamine oxidase inhibitors.
    Pharmacological research, 2008, Volume: 57, Issue:6

    Topics: Adipocytes; Adipose Tissue; Adipose Tissue, White; Adiposity; Amine Oxidase (Copper-Containing); Ani

2008
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition.
    The American journal of pathology, 2009, Volume: 174, Issue:3

    Topics: Adipose Tissue; Amine Oxidase (Copper-Containing); Animals; Cell Adhesion Molecules; Flow Cytometry;

2009
Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats.
    Pharmacological research, 2007, Volume: 56, Issue:1

    Topics: 3T3 Cells; Adipocytes; Adipose Tissue, White; Adult; Amine Oxidase (Copper-Containing); Animals; Ben

2007
Effects of histamine on triglyceride breakdown in mouse adipocytes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2007, Volume: 56 Suppl 1

    Topics: Adipocytes; Adrenergic beta-Agonists; Amine Oxidase (Copper-Containing); Animals; Carcinogens; Hista

2007
Reduction of fat deposition by combined inhibition of monoamine oxidases and semicarbazide-sensitive amine oxidases in obese Zucker rats.
    Pharmacological research, 2007, Volume: 56, Issue:6

    Topics: Adipocytes; Adipose Tissue, White; Amine Oxidase (Copper-Containing); Animals; Blood Glucose; Eating

2007