Page last updated: 2024-10-16

carbamic acid and Renal Insufficiency, Chronic

carbamic acid has been researched along with Renal Insufficiency, Chronic in 2 studies

carbamic acid : A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised.

Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nicolas, C1
Jaisson, S1
Gorisse, L1
Tessier, FJ1
Niquet-Léridon, C1
Jacolot, P1
Pietrement, C1
Gillery, P1
Behets, GJ1
Dams, G1
Damment, SJ1
Martin, P1
De Broe, ME1
D'Haese, PC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-label, Phase I, One-dose, One-meal, Balance Study Comparing the Absorption of Dietary Phosphorus When Administering FOSRENOL® (Lanthanum Carbonate) or RENVELA® (Sevelamer Carbonate) in Healthy Adult Volunteers[NCT00875017]Phase 131 participants (Actual)Interventional2009-04-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Net Calcium Absorption

Net Calcium Absorption (Lanthanum carbonate period) = Calcium ingested in meal minus (Rectal effluent calcium after Lanthanum carbonate + meal minus Rectal effluent calcium after fasting). Net Calcium Absorption (Sevelamer Carbonate period) = Calcium ingested in meal minus (Rectal effluent calcium after Sevelamer carbonate + meal minus Rectal effluent calcium after fasting). Net Calcium Absorption (Meal only period) = Calcium ingested in meal minus (Rectal effluent calcium after meal only minus Rectal effluent calcium after fasting). (NCT00875017)
Timeframe: 10 hours post-dose

Interventionmg (Least Squares Mean)
Lanthanum Carbonate49.46
Sevelamer Carbonate70.13
Meal Only65.02

Net Phosphorous Absorption

Net phosphorous absorption (Lanthanum carbonate period) = phosphorous ingested in meal minus (Rectal effluent phosphorous after Lanthanum carbonate + meal minus Rectal effluent phosphorous after fasting). Net phosphorous absorption (Sevelamer Carbonate period) = Phosphorous ingested in meal minus (Rectal effluent phosphorous after Sevelamer carbonate + meal minus Rectal effluent phosphorous after fasting). Net phosphorous absorption (Meal only period) = Phosphorous ingested in meal minus (Rectal effluent phosphorous after meal only minus Rectal effluent phosphorous after fasting). (NCT00875017)
Timeframe: 10 hours post-dose

Interventionmg (Least Squares Mean)
Lanthanum Carbonate156.03
Sevelamer Carbonate221.78
Meal Only281.68

Net Phosphorous Binding

Net Phosphorous Binding (Lanthanum carbonate period) = Rectal effluent phosphorous after Lanthanum carbonate + meal minus Rectal effluent phosphorous after meal only. Net Phosphorous Binding (Sevelamer carbonate period) = Rectal effluent phosphorous after Sevelamer carbonate + meal minus Rectal effluent phosphorous after meal only. (NCT00875017)
Timeframe: 10 hours post-dose

Interventionmg (Least Squares Mean)
Lanthanum Carbonate135.05
Sevelamer Carbonate63.15

Trials

1 trial available for carbamic acid and Renal Insufficiency, Chronic

ArticleYear
Differences in gastrointestinal calcium absorption after the ingestion of calcium-free phosphate binders.
    American journal of physiology. Renal physiology, 2014, Jan-01, Volume: 306, Issue:1

    Topics: Adult; Animals; Calcium; Carbamates; Cellulose; Chelating Agents; Female; Gastrointestinal Tract; Hu

2014

Other Studies

1 other study available for carbamic acid and Renal Insufficiency, Chronic

ArticleYear
Carbamylation is a competitor of glycation for protein modification in vivo.
    Diabetes & metabolism, 2018, Volume: 44, Issue:2

    Topics: Albumins; Animals; Blood Glucose; Blood Proteins; Carbamates; Cyanates; Diabetes Mellitus, Experimen

2018