carbamazepine epoxide has been researched along with Trigeminal Neuralgia in 5 studies
carbamazepine epoxide: metabolite of carbamazepine; RN given refers to unlabeled cpd
carbamazepine-10,11-epoxide : An epoxide and metabolite of carbamazepine.
Trigeminal Neuralgia: A syndrome characterized by recurrent episodes of excruciating pain lasting several seconds or longer in the sensory distribution of the TRIGEMINAL NERVE. Pain may be initiated by stimulation of trigger points on the face, lips, or gums or by movement of facial muscles or chewing. Associated conditions include MULTIPLE SCLEROSIS, vascular anomalies, ANEURYSMS, and neoplasms. (Adams et al., Principles of Neurology, 6th ed, p187)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clinical effects of carbamazepine-10,11-epoxide were assessed in six patients with trigeminal neuralgia." | 7.67 | Potent therapeutic effect of carbamazepine-10,11-epoxide in trigeminal neuralgia. ( Bertilsson, L; Tomson, T, 1984) |
| " Intracisternal strychnine in rats has been shown to result in localized trigeminal dynamic allodynia, thus representing a possible model of trigeminal neuralgia." | 3.79 | Evaluation of a novel mouse model of intracisternal strychnine-induced trigeminal allodynia. ( Lee, IO; MacLeod, BA; Puil, E; Ries, CR; Schwarz, SK; Whitehead, RA, 2013) |
| "The clinical effects of carbamazepine-10,11-epoxide were assessed in six patients with trigeminal neuralgia." | 3.67 | Potent therapeutic effect of carbamazepine-10,11-epoxide in trigeminal neuralgia. ( Bertilsson, L; Tomson, T, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, IO | 1 |
| Whitehead, RA | 1 |
| Ries, CR | 1 |
| Schwarz, SK | 1 |
| Puil, E | 1 |
| MacLeod, BA | 1 |
| Tomson, T | 1 |
| Bertilsson, L | 1 |
| Sinués, B | 1 |
| Gazulla, J | 1 |
| Bernal, ML | 1 |
| Lanuza, J | 1 |
| Fanlo, A | 1 |
| Saenz, MA | 1 |
| Barolome, M | 1 |
| Zakrzewska, JM | 1 |
| Ivanyi, L | 1 |
5 other studies available for carbamazepine epoxide and Trigeminal Neuralgia
| Article | Year |
|---|---|
Evaluation of a novel mouse model of intracisternal strychnine-induced trigeminal allodynia.
Topics: Analgesics, Non-Narcotic; Animals; Carbamazepine; Cerebrospinal Fluid; Cisterna Magna; Disease Model | 2013 |
Potent therapeutic effect of carbamazepine-10,11-epoxide in trigeminal neuralgia.
Topics: Aged; Carbamazepine; Female; Humans; Male; Middle Aged; Trigeminal Neuralgia | 1984 |
Six mutagenicity assays in exposure biomonitoring of patients receiving carbamazepine for epilepsy or trigeminal neuralgia.
Topics: Adolescent; Adult; Aged; Biotransformation; Carbamazepine; Case-Control Studies; Cell Division; Chil | 1995 |
Carbamazepine update.
Topics: Carbamazepine; Diuresis; Drug Evaluation; Drug Interactions; Epilepsy; Humans; Trigeminal Neuralgia | 1989 |
In vitro lymphocyte proliferation by carbamazepine, carbamazepine-10, 11-epoxide, and oxcarbazepine in the diagnosis of drug-induced hypersensitivity.
Topics: Administration, Oral; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Humans; Lymphocyte Acti | 1988 |