carbamazepine epoxide has been researched along with Pregnancy in 10 studies
carbamazepine epoxide: metabolite of carbamazepine; RN given refers to unlabeled cpd
carbamazepine-10,11-epoxide : An epoxide and metabolite of carbamazepine.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbamazepine is one of the three most frequently prescribed antiepileptic drugs in pregnancy." | 3.83 | Concentrations of carbamazepine and carbamazepine-10,11-epoxide in maternal and umbilical cord blood at birth: Influence of co-administration of valproic acid or enzyme-inducing antiepileptic drugs. ( Brozmanova, H; Grundmann, M; Kacirova, I, 2016) |
| " Phenobarbital cotreatment (45 mg/kg/day) with OXC (1100 mg/kg/day) did not lead to changes in the incidence of malformation when compared with OXC (1100 mg/kg/day) dosed alone." | 1.29 | Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse. ( Amore, BM; Bennett, GD; Finnell, RH; Kalhorn, TF; Nelson, SD; Skiles, GL; Slattery, JT; Wlodarczyk, B, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kacirova, I | 1 |
| Grundmann, M | 1 |
| Brozmanova, H | 1 |
| Koren, G | 1 |
| Kuhnz, W | 2 |
| Jäger-Roman, E | 1 |
| Rating, D | 1 |
| Deichl, A | 1 |
| Kunze, J | 1 |
| Helge, H | 1 |
| Nau, H | 3 |
| Steldinger, R | 1 |
| Omtzigt, JG | 1 |
| Los, FJ | 1 |
| Meijer, JW | 2 |
| Lindhout, D | 2 |
| Bennett, GD | 2 |
| Amore, BM | 1 |
| Finnell, RH | 2 |
| Wlodarczyk, B | 1 |
| Kalhorn, TF | 1 |
| Skiles, GL | 1 |
| Nelson, SD | 1 |
| Slattery, JT | 1 |
| Pienimäki, P | 1 |
| Lampela, E | 1 |
| Hakkola, J | 1 |
| Arvela, P | 1 |
| Raunio, H | 1 |
| Vähäkangas, K | 1 |
| Meinardi, H | 1 |
| Mohl, VK | 1 |
| Taylor, SM | 1 |
| Yerby, MS | 1 |
| Friel, PN | 1 |
| Miller, DQ | 1 |
10 other studies available for carbamazepine epoxide and Pregnancy
| Article | Year |
|---|---|
Concentrations of carbamazepine and carbamazepine-10,11-epoxide in maternal and umbilical cord blood at birth: Influence of co-administration of valproic acid or enzyme-inducing antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Dose-Response Relationsh | 2016 |
Comment on antiepileptics and antipsychotics.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Female; Folic Acid; Hematinics; Human | 2002 |
Carbamazepine and carbamazepine-10,11- epoxide during pregnancy and postnatal period in epileptic mother and their nursed infants: pharmacokinetics and clinical effects.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Female; | 1983 |
Protein binding of carbamazepine and its epoxide in maternal and fetal plasma at delivery: comparison to other anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Fatty Acids, | 1984 |
The 10,11-epoxide-10,11-diol pathway of carbamazepine in early pregnancy in maternal serum, urine, and amniotic fluid: effect of dose, comedication, and relation to outcome of pregnancy.
Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Carbamazepine; Cohort Studies; Dose-Response Relationsh | 1993 |
Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Female; Mice; Mice, Inbred Strains; Oxcarbazepine; Pregnanc | 1996 |
Pharmacokinetics of oxcarbazepine and carbamazepine in human placenta.
Topics: Anticonvulsants; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Epilepsy; Fe | 1997 |
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epi | 1992 |
Failure of epoxide formation to influence carbamazepine-induced teratogenesis in a mouse model.
Topics: Animals; Carbamazepine; Female; Fetal Blood; Fetal Growth Retardation; Mice; Mice, Inbred Strains; P | 1986 |
Carbamazepine protein binding and disposition in pregnancy.
Topics: Adult; Blood Proteins; Carbamazepine; Female; Humans; Maternal-Fetal Exchange; Metabolic Clearance R | 1985 |