carbamazepine epoxide has been researched along with Epilepsy, Complex Partial in 3 studies
carbamazepine epoxide: metabolite of carbamazepine; RN given refers to unlabeled cpd
carbamazepine-10,11-epoxide : An epoxide and metabolite of carbamazepine.
Epilepsy, Complex Partial: A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fifty-two children between the age of 2 weeks and 15 years were treated with CBZ (mean dosage 17 mg/kg body weight) either as mono- (n = 36) or in polytherapy (n = 16)." | 2.67 | The metabolization of carbamazepine to CBZ-10,11-epoxide in children from the newborn age to adolescence. ( Hannak, D; Haug, C; Korinthenberg, R, 1994) |
| " CBZ-E pharmacokinetic parameters in LTG-treated patients were found to be similar to those observed in controls (half-life: 7." | 1.29 | Single dose pharmacokinetics of carbamazepine-10,11-epoxide in patients on lamotrigine monotherapy. ( Fazio, A; Perucca, E; Pisani, F; Spina, E; Tomson, T; Xiao, B, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pisani, F | 2 |
| Xiao, B | 1 |
| Fazio, A | 2 |
| Spina, E | 2 |
| Perucca, E | 1 |
| Tomson, T | 1 |
| Korinthenberg, R | 1 |
| Haug, C | 1 |
| Hannak, D | 1 |
| Avenoso, A | 1 |
| Pollicino, AM | 1 |
| Caputi, AP | 1 |
2 trials available for carbamazepine epoxide and Epilepsy, Complex Partial
| Article | Year |
|---|---|
The metabolization of carbamazepine to CBZ-10,11-epoxide in children from the newborn age to adolescence.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child Development; Child, Preschool; | 1994 |
Carbamazepine coadministration with fluoxetine or fluvoxamine.
Topics: Adult; Carbamazepine; Depression; Drug Interactions; Drug Therapy, Combination; Epilepsy, Complex Pa | 1993 |
1 other study available for carbamazepine epoxide and Epilepsy, Complex Partial
| Article | Year |
|---|---|
Single dose pharmacokinetics of carbamazepine-10,11-epoxide in patients on lamotrigine monotherapy.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy, Complex Partial; Female; Humans; | 1994 |