carbamazepine epoxide has been researched along with Bipolar Disorder in 4 studies
carbamazepine epoxide: metabolite of carbamazepine; RN given refers to unlabeled cpd
carbamazepine-10,11-epoxide : An epoxide and metabolite of carbamazepine.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| " During the first week, the dosage was rapidly increased to 800 mg/day in order to produce steady-state plasma levels of carbamazepine on Day 7." | 1.28 | Carbamazepine and its 10,11-epoxide metabolite in acute mania: clinical and pharmacokinetic correlates. ( Alric, R; Blayac, JP; Cociglio, M; Hue, B; Lonjon, R; Petit, P; Pouget, R; Sluzewska, A, 1991) |
| "Levels of carbamazepine and its -10,11-epoxide metabolite were measured in plasma and CSF of affectively ill patients treated only with carbamazepine for an average of 33 days at an average dosage of 1,055 mg/day." | 1.27 | Carbamazepine and its -10,11-epoxide metabolite in plasma and CSF. Relationship to antidepressant response. ( Ballenger, JC; Bunney, WE; Chatterji, DC; Greene, RF; Post, RM; Uhde, TW, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Post, RM | 2 |
| Uhde, TW | 2 |
| Wolff, EA | 1 |
| Ballenger, JC | 1 |
| Chatterji, DC | 1 |
| Greene, RF | 1 |
| Bunney, WE | 1 |
| Petit, P | 1 |
| Lonjon, R | 1 |
| Cociglio, M | 1 |
| Sluzewska, A | 1 |
| Blayac, JP | 1 |
| Hue, B | 1 |
| Alric, R | 1 |
| Pouget, R | 1 |
| Chan, K | 1 |
1 trial available for carbamazepine epoxide and Bipolar Disorder
| Article | Year |
|---|---|
Profile of clinical efficacy and side effect of carbamazepine in psychiatric illness: relationship to blood and CSF levels of carbamazepine and its -10,11-epoxide metabolite.
Topics: Biotransformation; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Depressive Disorder; D | 1984 |
3 other studies available for carbamazepine epoxide and Bipolar Disorder
| Article | Year |
|---|---|
Carbamazepine and its -10,11-epoxide metabolite in plasma and CSF. Relationship to antidepressant response.
Topics: Adult; Aged; Bipolar Disorder; Carbamazepine; Depressive Disorder; Female; Humans; Male; Middle Aged | 1983 |
Carbamazepine and its 10,11-epoxide metabolite in acute mania: clinical and pharmacokinetic correlates.
Topics: Acute Disease; Adolescent; Adult; Aged; Bipolar Disorder; Carbamazepine; Female; Humans; Male; Middl | 1991 |
Simultaneous determination of carbamazepine and its epoxide metabolite in plasma and urine by high-performance liquid chromatography.
Topics: Bipolar Disorder; Carbamazepine; Chromatography, High Pressure Liquid; Drug Stability; Humans; Spect | 1985 |