carbamazepine epoxide has been researched along with Aging in 7 studies
carbamazepine epoxide: metabolite of carbamazepine; RN given refers to unlabeled cpd
carbamazepine-10,11-epoxide : An epoxide and metabolite of carbamazepine.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbamazepine (CBZ) used in the treatment of epilepsy, is metabolized in man to an active metabolite: carbamazepine 10-11 epoxide (CBZ-E)." | 3.68 | Distribution of carbamazepine and its epoxide in blood compartments in adolescent and adult epileptic patients. ( Bonneton, J; Genton, P; Mesdjian, E, 1992) |
| "Plasma carbamazepine (CBZ) and carbamazepine-10,11-epoxide (CBZ-E) concentrations were measured in 160 epileptic patients in order to determine the effect of factors such as age, daily dosing schedule, formulation, and combination with other antiepileptic drugs on these concentrations in relation to the daily dose." | 2.68 | Factors influencing plasma concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic children and adults. ( Bonato, PS; Campos, GM; Lanchote, VL; Rodrigues, I, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McKauge, L | 1 |
| Tyrer, JH | 1 |
| Eadie, MJ | 1 |
| van Boxtel, CJ | 1 |
| Rane, A | 1 |
| Brown, RD | 1 |
| Wilson, JT | 1 |
| Lanchote, VL | 1 |
| Bonato, PS | 1 |
| Campos, GM | 1 |
| Rodrigues, I | 1 |
| Liu, H | 2 |
| Delgado, MR | 2 |
| Bonneton, J | 1 |
| Genton, P | 1 |
| Mesdjian, E | 1 |
| Hockings, N | 1 |
| Pall, A | 1 |
| Moody, J | 1 |
| Davidson, AV | 1 |
| Davidson, DL | 1 |
3 trials available for carbamazepine epoxide and Aging
| Article | Year |
|---|---|
Factors influencing plasma concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic children and adults.
Topics: Adolescent; Adult; Aging; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Chromatography, H | 1995 |
Influence of sex, age, weight, and carbamazepine dose on serum concentrations, concentration ratios, and level/dose ratios of carbamazepine and its metabolites.
Topics: Aging; Body Weight; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilep | 1994 |
The effects of age on carbamazepine pharmacokinetics and adverse effects.
Topics: Adult; Aged; Aging; Carbamazepine; Double-Blind Method; Female; Humans; Kinetics; Male; Psychomotor | 1986 |
4 other studies available for carbamazepine epoxide and Aging
| Article | Year |
|---|---|
Factors influencing simultaneous concentrations of carbamazepine and its epoxide in plasma.
Topics: Adolescent; Adult; Aging; Anticonvulsants; Biotransformation; Carbamazepine; Drug Interactions; Fema | 1981 |
The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile.
Topics: Aging; Animals; Carbamazepine; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; | 1981 |
The influence of polytherapy on the relationships between serum carbamazepine and its metabolites in epileptic children.
Topics: Aging; Anticonvulsants; Body Weight; Carbamazepine; Child; Chromatography, High Pressure Liquid; Dru | 1994 |
Distribution of carbamazepine and its epoxide in blood compartments in adolescent and adult epileptic patients.
Topics: Adolescent; Adult; Aged; Aging; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; | 1992 |