carbamazepine epoxide has been researched along with Abdominal Epilepsy in 10 studies
carbamazepine epoxide: metabolite of carbamazepine; RN given refers to unlabeled cpd
carbamazepine-10,11-epoxide : An epoxide and metabolite of carbamazepine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In adults with focal seizures, adjunctive BRV treatment does not affect plasma concentrations of the evaluated AEDs but increases carbamazepine epoxide metabolite." | 5.30 | Pharmacokinetic interaction of brivaracetam on other antiepileptic drugs in adults with focal seizures: Pooled analysis of data from randomized clinical trials. ( Moseley, BD; Otoul, C; Staelens, L; Stockis, A, 2019) |
| "We studied the steady-state pharmacokinetic profile of topiramate (TPM) as a function of dose and the effects of comedication with carbamazepine (CBZ)." | 2.68 | Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy. ( Doose, DR; Kramer, LD; Nayak, RK; Sachdeo, RC; Sachdeo, SK; Walker, SA, 1996) |
| " Fifty-two children between the age of 2 weeks and 15 years were treated with CBZ (mean dosage 17 mg/kg body weight) either as mono- (n = 36) or in polytherapy (n = 16)." | 2.67 | The metabolization of carbamazepine to CBZ-10,11-epoxide in children from the newborn age to adolescence. ( Hannak, D; Haug, C; Korinthenberg, R, 1994) |
| "We evaluated the efficacy, development of adverse effects, and possible correlation between the plasma concentration of carbamazepine (CBZ) and its major metabolite, carbamazepine-10,11-epoxide (CBZ-E), in a group of epileptic patients in whom selective increases in CBZ doses were made." | 2.67 | Carbamazepine and its epoxide: an open study of efficacy and side effects after carbamazepine dose increment in refractory partial epilepsy. ( Baulac, M; Gimenez, F; Laplane, D; Longer, E; Semah, F; Thuillier, A, 1994) |
| " Mean concentration values also differed significantly, which is explained by a somewhat reduced bioavailability (22% less) of the slow-release formulation." | 2.67 | Diurnal variation of carbamazepine and carbamazepine-10,11-epoxide in plasma and saliva in children with epilepsy: a comparison between conventional and slow-release formulations. ( Arvidsson, J; Eeg-Olofsson, O; Grahn, PA; Gylje, H; Larsson, C; Nilsson, HL; Norén, L; Tonnby, B, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moseley, BD | 1 |
| Otoul, C | 1 |
| Staelens, L | 1 |
| Stockis, A | 1 |
| Steinhoff, BJ | 1 |
| Bacher, M | 1 |
| Blickhan, M | 1 |
| Bernedo, V | 1 |
| Dietmann, D | 1 |
| Intravooth, T | 1 |
| Kornmeier, R | 1 |
| Kurth, C | 1 |
| Mahn, P | 1 |
| Schneider, M | 1 |
| Stockinger, J | 1 |
| Staack, AM | 1 |
| Korinthenberg, R | 1 |
| Haug, C | 1 |
| Hannak, D | 1 |
| Semah, F | 1 |
| Gimenez, F | 1 |
| Longer, E | 1 |
| Laplane, D | 1 |
| Thuillier, A | 1 |
| Baulac, M | 1 |
| Gidal, BE | 1 |
| Spencer, NW | 1 |
| Maly, MM | 1 |
| Pitterle, ME | 1 |
| Sachdeo, RC | 1 |
| Sachdeo, SK | 1 |
| Walker, SA | 1 |
| Kramer, LD | 1 |
| Nayak, RK | 1 |
| Doose, DR | 1 |
| Miura, H | 1 |
| Eeg-Olofsson, O | 1 |
| Nilsson, HL | 1 |
| Tonnby, B | 1 |
| Arvidsson, J | 1 |
| Grahn, PA | 1 |
| Gylje, H | 1 |
| Larsson, C | 1 |
| Norén, L | 1 |
| Benetello, P | 1 |
| Furlanut, M | 1 |
| Perlotto, N | 1 |
| Rapeport, WG | 1 |
1 review available for carbamazepine epoxide and Abdominal Epilepsy
| Article | Year |
|---|---|
Factors influencing the relationship between carbamazepine plasma concentration and its clinical effects in patients with epilepsy.
Topics: Brain Chemistry; Carbamazepine; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, | 1985 |
6 trials available for carbamazepine epoxide and Abdominal Epilepsy
| Article | Year |
|---|---|
Pharmacokinetic interaction of brivaracetam on other antiepileptic drugs in adults with focal seizures: Pooled analysis of data from randomized clinical trials.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Resistant Epilepsy; Epilepsies, Partial; Female; Humans; | 2019 |
The metabolization of carbamazepine to CBZ-10,11-epoxide in children from the newborn age to adolescence.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child Development; Child, Preschool; | 1994 |
Carbamazepine and its epoxide: an open study of efficacy and side effects after carbamazepine dose increment in refractory partial epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Drug Therapy, Combination; Epilepsies, Partial; Female; Huma | 1994 |
Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy.
Topics: Adult; Anticonvulsants; Biological Availability; Carbamazepine; Dose-Response Relationship, Drug; Dr | 1996 |
Developmental and therapeutic pharmacology of antiepileptic drugs.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Admini | 2000 |
Diurnal variation of carbamazepine and carbamazepine-10,11-epoxide in plasma and saliva in children with epilepsy: a comparison between conventional and slow-release formulations.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Circadian Rhythm; Delayed-Action Preparations; E | 1990 |
3 other studies available for carbamazepine epoxide and Abdominal Epilepsy
| Article | Year |
|---|---|
Is brivaracetam-induced elevation of carbamazepine-epoxide levels common and clinically relevant? - A case series.
Topics: Adult; Carbamazepine; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Pyrrolidinones; Seizur | 2020 |
Evaluation of carbamazepine and carbamazepine-epoxide protein binding in patients undergoing epilepsy surgery.
Topics: Adult; Blood Proteins; Carbamazepine; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; | 1996 |
Carbamazepine and carbamazepine-epoxide serum concentrations in some resistant cases of complex partial seizures.
Topics: Adolescent; Adult; Carbamazepine; Dose-Response Relationship, Drug; Epilepsies, Partial; Female; Hum | 1989 |