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carbamazepine and Weight Gain

carbamazepine has been researched along with Weight Gain in 24 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"Changes in body weight were evaluated in 349 patients from a study comparing efficacy of add-on therapy with tiagabine (TGB), carbamazepine (CBZ) or phenytoin (PHT)."9.09Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin. ( Bertrand, ME; Deaton, RL; Hogan, RE; Sommerville, KW, 2000)
" This paper presents an analysis of body weight data gathered during a randomized trial comparing valproate with carbamazepine in 260 children aged 4-15 years with newly-diagnosed epilepsy."9.08Weight gain with valproate or carbamazepine--a reappraisal. ( Easter, D; O'Bryan-Tear, CG; Verity, C, 1997)
"We have analyzed the records retrospectively and interviewed 70 adult patients attending an epilepsy clinic on VPA mono- or polytherapy followed over a median of 27 months (range 3-189), as well as 20 patients on carbamazepine (CBZ) monotherapy."9.08Weight gain in epileptic patients during treatment with valproic acid: a retrospective study. ( Corman, CL; Guberman, AH; Leung, NM, 1997)
"This retrospective longitudinal study included 85 VPA-treated and 93 carbamazepine (CBZ)-treated (as a reference) young patients with epilepsy."7.83Cytochrome P450 2C19 polymorphisms and valproic acid-induced weight gain. ( Ishitsu, T; Kajiwara, A; Nakagawa, K; Noai, M; Oniki, K; Saruwatari, J; Soraoka, H; Tanamachi, Y, 2016)
"Studies of the effect of oxcarbazepine (OXC) on body growth of children with epilepsy are rare and their results are controversial."7.83Weight gain in children on oxcarbazepine monotherapy. ( Attilakos, A; Garoufi, A; Katsarou, E; Koemtzidou, E; Kossiva, L; Soldatou, A; Tsentidis, C; Vartzelis, G, 2016)
"We evaluated the serum leptin and insulin as predictors of weight gain in children receiving long-term treatment with valproate (VPA), carbamazepine (CBZ), lamotrigine (LTG)."7.75States of serum leptin and insulin in children with epilepsy: risk predictors of weight gain. ( Fida, NM; Hamed, EA; Hamed, SA, 2009)
" This retrospective study of children with epilepsy, aged <12 years at enrollment, examined weight gain associated with valproic acid or carbamazepine monotherapy."7.74Lack of valproic acid-associated weight gain in prepubertal children. ( Baumann, RJ; Espinosa, PS; Mendiondo, MS; Robertson, WC; Salazar, JC; Yu, L, 2008)
"The effect of aging on carbamazepine (CBZ) plasma level/dose ratio was evaluated retrospectively in 15 children who were receiving CBZ monotherapy and who were followed up for at least 3 years."7.68A within-subject analysis of carbamazepine disposition related to development in children with epilepsy. ( Albani, F; Baruzzi, A; Contin, M; Riva, R, 1992)
"Four young patients who developed weight gain induced by carbamazepine therapy are described."7.68Weight gain, increased appetite, and excessive food intake induced by carbamazepine. ( Eshel, Y; Lampl, Y; Rapaport, A; Sarova-Pinhas, I, 1991)
"Oxcarbazepine was developed to attempt to reduce the side effects that have traditionally been observed with antiepileptic drugs that induce the hepatic enzyme system."5.33Central hypothyroidism with oxcarbazepine therapy. ( Carney, P; Miller, J, 2006)
"Diurnal weight gain was abnormal among 149 institutionalized chronically psychotic patients."5.28Antipsychotic drugs, lithium, carbamazepine, and abnormal diurnal weight gain in psychosis. ( Godleski, L; Harrington, D; Hundley, P; Vieweg, V; Yank, G, 1989)
"Changes in body weight were evaluated in 349 patients from a study comparing efficacy of add-on therapy with tiagabine (TGB), carbamazepine (CBZ) or phenytoin (PHT)."5.09Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin. ( Bertrand, ME; Deaton, RL; Hogan, RE; Sommerville, KW, 2000)
" This paper presents an analysis of body weight data gathered during a randomized trial comparing valproate with carbamazepine in 260 children aged 4-15 years with newly-diagnosed epilepsy."5.08Weight gain with valproate or carbamazepine--a reappraisal. ( Easter, D; O'Bryan-Tear, CG; Verity, C, 1997)
"We have analyzed the records retrospectively and interviewed 70 adult patients attending an epilepsy clinic on VPA mono- or polytherapy followed over a median of 27 months (range 3-189), as well as 20 patients on carbamazepine (CBZ) monotherapy."5.08Weight gain in epileptic patients during treatment with valproic acid: a retrospective study. ( Corman, CL; Guberman, AH; Leung, NM, 1997)
"This retrospective longitudinal study included 85 VPA-treated and 93 carbamazepine (CBZ)-treated (as a reference) young patients with epilepsy."3.83Cytochrome P450 2C19 polymorphisms and valproic acid-induced weight gain. ( Ishitsu, T; Kajiwara, A; Nakagawa, K; Noai, M; Oniki, K; Saruwatari, J; Soraoka, H; Tanamachi, Y, 2016)
"Studies of the effect of oxcarbazepine (OXC) on body growth of children with epilepsy are rare and their results are controversial."3.83Weight gain in children on oxcarbazepine monotherapy. ( Attilakos, A; Garoufi, A; Katsarou, E; Koemtzidou, E; Kossiva, L; Soldatou, A; Tsentidis, C; Vartzelis, G, 2016)
"We evaluated the serum leptin and insulin as predictors of weight gain in children receiving long-term treatment with valproate (VPA), carbamazepine (CBZ), lamotrigine (LTG)."3.75States of serum leptin and insulin in children with epilepsy: risk predictors of weight gain. ( Fida, NM; Hamed, EA; Hamed, SA, 2009)
" This retrospective study of children with epilepsy, aged <12 years at enrollment, examined weight gain associated with valproic acid or carbamazepine monotherapy."3.74Lack of valproic acid-associated weight gain in prepubertal children. ( Baumann, RJ; Espinosa, PS; Mendiondo, MS; Robertson, WC; Salazar, JC; Yu, L, 2008)
"The effect of aging on carbamazepine (CBZ) plasma level/dose ratio was evaluated retrospectively in 15 children who were receiving CBZ monotherapy and who were followed up for at least 3 years."3.68A within-subject analysis of carbamazepine disposition related to development in children with epilepsy. ( Albani, F; Baruzzi, A; Contin, M; Riva, R, 1992)
"Four young patients who developed weight gain induced by carbamazepine therapy are described."3.68Weight gain, increased appetite, and excessive food intake induced by carbamazepine. ( Eshel, Y; Lampl, Y; Rapaport, A; Sarova-Pinhas, I, 1991)
"Usually, no adverse effects are observed in breastfed infants whose mothers are treated with the anti-epileptic carbamazepine."1.48Maternal Carbamazepine Therapy and Unusual Adverse Effects in a Breastfed Infant. ( Antonucci, R; Cherchi, C; Cuzzolin, L; Locci, C; Manconi, A; Oggiano, AM, 2018)
"Weight gain was found to be lower in the elderly for antipsychotic drugs, in particular for olanzapine."1.39Age and adverse drug reactions from psychopharmacological treatment: data from the AMSP drug surveillance programme in Switzerland. ( Baumann, P; Greil, W; Grohmann, R; Häberle, A; Schuhmann, T, 2013)
"Weight gain was seen in 66."1.36Modification in body weight associated with antiepileptic drugs. ( Gaspari, CN; Guerreiro, CA, 2010)
"Absence status was aggravated with carbamazepine and generalised tonic-clonic seizures were not controlled with ethosuximide."1.36Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status. ( Genton, P; Velizarova, R, 2010)
"Oxcarbazepine was developed to attempt to reduce the side effects that have traditionally been observed with antiepileptic drugs that induce the hepatic enzyme system."1.33Central hypothyroidism with oxcarbazepine therapy. ( Carney, P; Miller, J, 2006)
"Juvenile myoclonic epilepsy is a common, under-recognised form of epilepsy which is best treated with sodium valproate."1.29Juvenile myoclonic epilepsy: diagnosis, management and outcome. ( Buchanan, N; Sharpe, C, 1995)
"Diurnal weight gain was abnormal among 149 institutionalized chronically psychotic patients."1.28Antipsychotic drugs, lithium, carbamazepine, and abnormal diurnal weight gain in psychosis. ( Godleski, L; Harrington, D; Hundley, P; Vieweg, V; Yank, G, 1989)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's9 (37.50)18.2507
2000's5 (20.83)29.6817
2010's7 (29.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antonucci, R1
Cuzzolin, L1
Manconi, A1
Cherchi, C1
Oggiano, AM1
Locci, C1
Greil, W1
Häberle, A1
Schuhmann, T1
Grohmann, R1
Baumann, P1
Noai, M1
Soraoka, H1
Kajiwara, A1
Tanamachi, Y1
Oniki, K1
Nakagawa, K1
Ishitsu, T1
Saruwatari, J1
Garoufi, A1
Vartzelis, G1
Tsentidis, C1
Attilakos, A1
Koemtzidou, E1
Kossiva, L1
Katsarou, E1
Soldatou, A1
Hamed, SA1
Fida, NM1
Hamed, EA1
Espinosa, PS1
Salazar, JC1
Yu, L1
Mendiondo, MS1
Robertson, WC1
Baumann, RJ1
Prodam, F1
Bellone, S1
Casara, G1
De Rienzo, F1
Grassino, EC1
Bonsignori, I1
Demarchi, I1
Rapa, A1
Radetti, G1
Bona, G1
Gaspari, CN1
Guerreiro, CA1
Velizarova, R1
Genton, P1
Miller, J1
Carney, P1
Sharpe, C1
Buchanan, N1
Baptista, T1
Weiss, SR1
Post, RM1
Easter, D1
O'Bryan-Tear, CG1
Verity, C1
Corman, CL1
Leung, NM1
Guberman, AH1
Schaller, JL1
Behar, D1
Hogan, RE1
Bertrand, ME1
Deaton, RL1
Sommerville, KW1
Ranganath, HN1
Tu, JB1
Hartridge, C1
Izawa, J1
Albani, F1
Riva, R1
Contin, M1
Baruzzi, A1
Coxhead, N1
Silverstone, T1
Cookson, J1
Lampl, Y1
Eshel, Y1
Rapaport, A1
Sarova-Pinhas, I1
Brady, KT1
Vieweg, WV1
Godleski, LS1
Shannon, C1
Hundley, PL1
Yank, GR1
Vieweg, V1
Godleski, L1
Hundley, P1
Harrington, D1
Yank, G1

Reviews

1 review available for carbamazepine and Weight Gain

ArticleYear
Weight gain associated with psychotropic drugs.
    Southern medical journal, 1989, Volume: 82, Issue:5

    Topics: Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Humans; Lithium; Monoamine Oxidase Inhib

1989

Trials

4 trials available for carbamazepine and Weight Gain

ArticleYear
Weight gain with valproate or carbamazepine--a reappraisal.
    Seizure, 1997, Volume: 6, Issue:2

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross-Over Studies; Dose-Respon

1997
Weight gain in epileptic patients during treatment with valproic acid: a retrospective study.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1997, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged

1997
Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin.
    Epilepsy research, 2000, Volume: 41, Issue:1

    Topics: Anticonvulsants; Body Weight; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Epileps

2000
Carbamazepine versus lithium in the prophylaxis of bipolar affective disorder.
    Acta psychiatrica Scandinavica, 1992, Volume: 85, Issue:2

    Topics: Adult; Aged; Bipolar Disorder; Carbamazepine; Double-Blind Method; Electrocardiography; Female; Huma

1992

Other Studies

19 other studies available for carbamazepine and Weight Gain

ArticleYear
Maternal Carbamazepine Therapy and Unusual Adverse Effects in a Breastfed Infant.
    Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2018, Volume: 13, Issue:2

    Topics: Adult; Anticonvulsants; Bottle Feeding; Breast Feeding; Carbamazepine; Child of Impaired Parents; Ep

2018
Age and adverse drug reactions from psychopharmacological treatment: data from the AMSP drug surveillance programme in Switzerland.
    Swiss medical weekly, 2013, Volume: 143

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An

2013
Cytochrome P450 2C19 polymorphisms and valproic acid-induced weight gain.
    Acta neurologica Scandinavica, 2016, Volume: 133, Issue:3

    Topics: Adolescent; Anticonvulsants; Body Mass Index; Carbamazepine; Child; Cytochrome P-450 CYP2C19; Epilep

2016
Weight gain in children on oxcarbazepine monotherapy.
    Epilepsy research, 2016, Volume: 122

    Topics: Adolescent; Anticonvulsants; Body Mass Index; Carbamazepine; Child; Child, Preschool; Epilepsy; Fema

2016
States of serum leptin and insulin in children with epilepsy: risk predictors of weight gain.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2009, Volume: 13, Issue:3

    Topics: Adolescent; Age Factors; Anticonvulsants; Body Mass Index; Carbamazepine; Case-Control Studies; Chil

2009
Lack of valproic acid-associated weight gain in prepubertal children.
    Pediatric neurology, 2008, Volume: 39, Issue:3

    Topics: Adolescent; Anticonvulsants; Body Height; Body Mass Index; Body Weight; Carbamazepine; Child; Child,

2008
Ghrelin levels are reduced in prepubertal epileptic children under treatment with carbamazepine or valproic acid.
    Epilepsia, 2010, Volume: 51, Issue:2

    Topics: Age Factors; Anticonvulsants; Body Height; Body Mass Index; Carbamazepine; Child; Depression, Chemic

2010
Modification in body weight associated with antiepileptic drugs.
    Arquivos de neuro-psiquiatria, 2010, Volume: 68, Issue:2

    Topics: Adult; Anticonvulsants; Body Mass Index; Carbamazepine; Epilepsy; Female; Humans; Male; Valproic Aci

2010
Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status.
    Epileptic disorders : international epilepsy journal with videotape, 2010, Volume: 12, Issue:4

    Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Diagnosis, Differential; Dose-Response Relationship, D

2010
Central hypothyroidism with oxcarbazepine therapy.
    Pediatric neurology, 2006, Volume: 34, Issue:3

    Topics: Adolescent; Anticonvulsants; Body Height; Carbamazepine; Child; Dose-Response Relationship, Drug; Fe

2006
Juvenile myoclonic epilepsy: diagnosis, management and outcome.
    The Medical journal of Australia, 1995, Feb-06, Volume: 162, Issue:3

    Topics: Adolescent; Adult; Alcohol Drinking; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Female;

1995
Carbamazepine attenuates cocaine-induced increases in dopamine in the nucleus accumbens: an in vivo dialysis study.
    European journal of pharmacology, 1993, May-12, Volume: 236, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbamazepine; Cocaine; Dialysis; Dopamine; Homovanillic Ac

1993
Carbamazepine and methylphenidate in ADHD.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1999, Volume: 38, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Drug Administration Schedu

1999
Carbamazepine and weight gain.
    Neurology India, 2000, Volume: 48, Issue:3

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Female; Humans; Male; Weight Gain

2000
Psychopharmacogenetic aspects of Prader-Willi syndrome.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1992, Volume: 31, Issue:6

    Topics: Adolescent; Aggression; Appetite Depressants; Behavior Therapy; Carbamazepine; Combined Modality The

1992
A within-subject analysis of carbamazepine disposition related to development in children with epilepsy.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:6

    Topics: Adolescent; Aging; Carbamazepine; Child; Child Development; Child, Preschool; Dose-Response Relation

1992
Weight gain, increased appetite, and excessive food intake induced by carbamazepine.
    Clinical neuropharmacology, 1991, Volume: 14, Issue:3

    Topics: Adolescent; Appetite; Carbamazepine; Child; Eating; Epilepsy; Female; Humans; Male; Weight Gain

1991
Normalization of abnormal diurnal weight gain among chronically psychotic geriatric patients. Is abnormal diurnal weight gain a risk factor in chronic psychosis?
    The Journal of nervous and mental disease, 1989, Volume: 177, Issue:9

    Topics: Adult; Aged; Antipsychotic Agents; Blood Pressure; Carbamazepine; Chronic Disease; Circadian Rhythm;

1989
Antipsychotic drugs, lithium, carbamazepine, and abnormal diurnal weight gain in psychosis.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1989, Volume: 2, Issue:1

    Topics: Adult; Antipsychotic Agents; Body Water; Carbamazepine; Circadian Rhythm; Female; Humans; Lithium; M

1989