Page last updated: 2024-10-24

carbamazepine and Uremia

carbamazepine has been researched along with Uremia in 6 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Phenytoin assays were evaluated using an additional set of samples from patients with abnormal renal function."1.31Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer. ( Annesley, TM; Frank, EL; Juenke, J; Roberts, WL; Schwarz, EL, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frank, EL1
Schwarz, EL1
Juenke, J1
Annesley, TM1
Roberts, WL1
Reiter, K1
Bordoni, V1
Dall'Olio, G1
Ricatti, MG1
Soli, M1
Ruperti, S1
Soffiati, G1
Galloni, E1
D'Intini, V1
Bellomo, R1
Ronco, C1
Dasgupta, A2
Thompson, WC1
Volk, A1
Zarday, Z1
Soberman, RJ1
Beyer, C1
Spiteller, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cytokine Adsorption in Severe, Refractory Septic Shock[NCT04910893]48 participants (Actual)Interventional2014-11-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for carbamazepine and Uremia

ArticleYear
Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer.
    American journal of clinical pathology, 2002, Volume: 118, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Cross Reactions; Drug Monitori

2002
In vitro removal of therapeutic drugs with a novel adsorbent system.
    Blood purification, 2002, Volume: 20, Issue:4

    Topics: Adsorption; Anti-Bacterial Agents; Biocompatible Materials; Carbamazepine; Digoxin; Glycopeptides; H

2002
Carbamazepine-salicylate interaction in normal and uremic sera: reduced interaction in uremic sera.
    Therapeutic drug monitoring, 1995, Volume: 17, Issue:2

    Topics: Carbamazepine; Drug Interactions; Hippurates; Humans; Salicylates; Salicylic Acid; Sulfates; Uremia

1995
Displacement of valproic acid and carbamazepine from protein binding in normal and uremic sera by tolmetin, ibuprofen, and naproxen: presence of inhibitor in uremic serum that blocks valproic acid-naproxen interactions.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:3

    Topics: Binding, Competitive; Blood Proteins; Carbamazepine; Cyclooxygenase Inhibitors; Drug Interactions; H

1996
Letter: Carbamazepine in uremic neuropathy.
    Annals of internal medicine, 1976, Volume: 84, Issue:3

    Topics: Carbamazepine; Humans; Peripheral Nervous System Diseases; Uremia

1976
A new carbamazepine metabolite in uraemic filtrate.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:8

    Topics: Carbamazepine; Female; Glucuronates; Humans; Mass Spectrometry; Middle Aged; Uremia

1992