carbamazepine has been researched along with Tuberous Sclerosis in 10 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a young child with tuberous sclerosis and cardiac rhabdomyoma who developed reversible heart block after being placed on carbamazepine treatment for seizures." | 7.68 | Carbamazepine-induced heart block in a child with tuberous sclerosis and cardiac rhabdomyoma: implications for evaluation and follow-up. ( Pollack, P; Weig, SG, 1993) |
| "We describe a young child with tuberous sclerosis and cardiac rhabdomyoma who developed reversible heart block after being placed on carbamazepine treatment for seizures." | 3.68 | Carbamazepine-induced heart block in a child with tuberous sclerosis and cardiac rhabdomyoma: implications for evaluation and follow-up. ( Pollack, P; Weig, SG, 1993) |
| "Tuberous sclerosis is an autosomal dominant inherited phakomatosis." | 1.36 | [Tuberous sclerosis and intracranial aneurysms: a rare association]. ( Aissi, M; Boughammoura-Bouatay, A; Frih-Ayed, M; Jerbi-Ommezzine, S; Sfar, MH; Younes-Mhenni, S, 2010) |
| "Tuberous sclerosis or Tuberous Sclerosis Complex (TSC) is a genetic disorder characterized by the growth of numerous benign tumours in many parts of the body caused by mutations on either of two genes, TSC1 and TSC2." | 1.36 | Tuberous sclerosis. ( Syed, KN, 2010) |
| "There was a dramatic reduction in seizure frequency with rapamycin therapy." | 1.35 | Rapamycin reduces seizure frequency in tuberous sclerosis complex. ( Butler, IJ; Koenig, MK; Muncy, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chemaly, N | 1 |
| Nehlig, A | 1 |
| Chiron, C | 1 |
| Nabbout, R | 1 |
| Fallah, A | 1 |
| Weil, AG | 1 |
| Wang, S | 1 |
| Lewis, E | 1 |
| Baca, CB | 1 |
| Mathern, GW | 1 |
| Muncy, J | 1 |
| Butler, IJ | 1 |
| Koenig, MK | 1 |
| Aissi, M | 1 |
| Younes-Mhenni, S | 1 |
| Jerbi-Ommezzine, S | 1 |
| Boughammoura-Bouatay, A | 1 |
| Frih-Ayed, M | 1 |
| Sfar, MH | 1 |
| Syed, KN | 1 |
| Ghosh, C | 1 |
| Marchi, N | 1 |
| Desai, NK | 1 |
| Puvenna, V | 1 |
| Hossain, M | 1 |
| Gonzalez-Martinez, J | 1 |
| Alexopoulos, AV | 1 |
| Janigro, D | 1 |
| Nandhagopal, R | 1 |
| Pejrone, F | 1 |
| Piccinini, GP | 1 |
| De Maria, F | 1 |
| Buccheri, G | 1 |
| Knilans, TK | 1 |
| Weig, SG | 1 |
| Pollack, P | 1 |
10 other studies available for carbamazepine and Tuberous Sclerosis
| Article | Year |
|---|---|
Electrocorticographic telemetric recording in unrestrained mouse pups.
Topics: Animals; Behavior, Animal; Brain; Carbamazepine; Electrocorticography; Epilepsy; Female; Male; Mice, | 2018 |
Cost-utility analysis of competing treatment strategies for drug-resistant epilepsy in children with Tuberous Sclerosis Complex.
Topics: Anticonvulsants; Carbamazepine; Child; Cost-Benefit Analysis; Diet, Ketogenic; Drug Resistant Epilep | 2016 |
Rapamycin reduces seizure frequency in tuberous sclerosis complex.
Topics: Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Dose-Response Relationship, Drug; Drug Thera | 2009 |
[Tuberous sclerosis and intracranial aneurysms: a rare association].
Topics: Adult; Anticonvulsants; Aspirin; Carbamazepine; Carotid Artery Diseases; Humans; Intracranial Aneury | 2010 |
Tuberous sclerosis.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Levetiracetam; Mutation; Piracetam; Tuberous | 2010 |
Cellular localization and functional significance of CYP3A4 in the human epileptic brain.
Topics: Adolescent; Adult; Anticonvulsants; Apoptosis; Astrocytes; ATP Binding Cassette Transporter, Subfami | 2011 |
Seizure and skin lesions.
Topics: Anticonvulsants; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Magnetic Resonance Imaging; Male; Sk | 2013 |
[A case of Pringle-Bourneville disease].
Topics: Adult; Carbamazepine; Epilepsy; Epilepsy, Absence; Female; Humans; Phenobarbital; Tuberous Sclerosis | 1981 |
Carbamazepine-induced atrioventricular block in a child with tuberous sclerosis and cardiac rhabdomyoma.
Topics: Carbamazepine; Heart Block; Heart Neoplasms; Humans; Infant; Rhabdomyoma; Tuberous Sclerosis | 1994 |
Carbamazepine-induced heart block in a child with tuberous sclerosis and cardiac rhabdomyoma: implications for evaluation and follow-up.
Topics: Anticonvulsants; Carbamazepine; Follow-Up Studies; Heart Block; Heart Neoplasms; Humans; Infant; Mal | 1993 |