Page last updated: 2024-10-24

carbamazepine and Tinnitus

carbamazepine has been researched along with Tinnitus in 39 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Intratympanic steroid injection has positive effects similar to those of oral carbamazepine in subjective tinnitus."9.14Treatment of subjective tinnitus: a comparative clinical study of intratympanic steroid injection vs. oral carbamazepine. ( Chen, F; Cui, X; Dai, Y; Ding, X; Du, X; She, W, 2009)
"A prospective study was designed to compare the efficacies of intratympanic prednisolone injection, intratympanic dexamethasone injection and carbamazepine by oral administration for subjective tinnitus."9.13[A short term study on the efficacies of intratympanic prednisolone and dexamethasone injection for subjective tinnitus]. ( Chen, F; Cui, X; Dai, Y; Du, X; Jiang, P; She, W; Zhang, Q, 2008)
"To determine whether carbamazepine is effective in treating the subjective tinnitus."9.13[Efficacy of carbamazepine combined with flunarizine hydrochloride for treating tinnitus]. ( Kong, X; Li, N; Ma, F; Xin, Y; Zhao, Y, 2008)
"The authors conclude that intravenous lidocaine is effective in reducing intractable tinnitus and that there is a close association between lidocaine and oral carbamazepine effects."9.09Lidocaine test in patients with tinnitus: rationale of accomplishment and relation to the treatment with carbamazepine. ( Balbani, AP; Bento, RF; Bittar, RS; Câmara, J; Sanchez, TG, 1999)
"A double-blind controlled trial on the use of oral carbamazepine in the treatment of tinnitus is reported."9.05The value of carbamazepine in the treatment of tinnitus. ( Hulshof, JH; Vermeij, P, 1985)
"Typewriter tinnitus (TT) is a rare subtype of tinnitus but different in many ways, and it is treatable in most cases with carbamazepine."8.12[Typewriter tinnitus treated with gabapentin]. ( Sehested, PC, 2022)
" Duration of tinnitus was the most important long-term prognostic factor of the carbamazepine trial, which indicates the importance of its earlier diagnosis."7.96Typewriter tinnitus: An investigative comparison with middle ear myoclonic tinnitus and its long-term therapeutic response to carbamazepine. ( Ashaikh, HK; Han, JS; Kim, DK; Park, JM; Park, SN; Park, SY; Vidal, JL, 2020)
" The associated bilateral asynchronous clicking tinnitus responded to carbamazepine."7.76Carbamazepine responsive typewriter tinnitus from basilar invagination. ( Handzel, O; Levine, RA; Nam, EC, 2010)
"Six subjects with similar unilateral tinnitus that was fully suppressed by carbamazepine have been identified."7.73Typewriter tinnitus: a carbamazepine-responsive syndrome related to auditory nerve vascular compression. ( Levine, RA, 2006)
"Carbamazepine was given as the treatment."5.26Carbamazepine in the treatment of objective myoclonus tinnitus. ( Häkkinen, V; Rahko, T, 1979)
"Intratympanic steroid injection has positive effects similar to those of oral carbamazepine in subjective tinnitus."5.14Treatment of subjective tinnitus: a comparative clinical study of intratympanic steroid injection vs. oral carbamazepine. ( Chen, F; Cui, X; Dai, Y; Ding, X; Du, X; She, W, 2009)
"A prospective study was designed to compare the efficacies of intratympanic prednisolone injection, intratympanic dexamethasone injection and carbamazepine by oral administration for subjective tinnitus."5.13[A short term study on the efficacies of intratympanic prednisolone and dexamethasone injection for subjective tinnitus]. ( Chen, F; Cui, X; Dai, Y; Du, X; Jiang, P; She, W; Zhang, Q, 2008)
"To determine whether carbamazepine is effective in treating the subjective tinnitus."5.13[Efficacy of carbamazepine combined with flunarizine hydrochloride for treating tinnitus]. ( Kong, X; Li, N; Ma, F; Xin, Y; Zhao, Y, 2008)
"The authors conclude that intravenous lidocaine is effective in reducing intractable tinnitus and that there is a close association between lidocaine and oral carbamazepine effects."5.09Lidocaine test in patients with tinnitus: rationale of accomplishment and relation to the treatment with carbamazepine. ( Balbani, AP; Bento, RF; Bittar, RS; Câmara, J; Sanchez, TG, 1999)
"A double-blind controlled trial on the use of oral carbamazepine in the treatment of tinnitus is reported."5.05The value of carbamazepine in the treatment of tinnitus. ( Hulshof, JH; Vermeij, P, 1985)
"Vestibular paroxysmia is defined as paroxysmal, brief, and carbamazepine-responsive vertigo."4.89Vestibular paroxysmia associated with paroxysmal pulsatile tinnitus: a case report and review of the literature. ( Chang, TP; Hsu, YC; Wu, YC, 2013)
"Typewriter tinnitus (TT) is a rare subtype of tinnitus but different in many ways, and it is treatable in most cases with carbamazepine."4.12[Typewriter tinnitus treated with gabapentin]. ( Sehested, PC, 2022)
" Duration of tinnitus was the most important long-term prognostic factor of the carbamazepine trial, which indicates the importance of its earlier diagnosis."3.96Typewriter tinnitus: An investigative comparison with middle ear myoclonic tinnitus and its long-term therapeutic response to carbamazepine. ( Ashaikh, HK; Han, JS; Kim, DK; Park, JM; Park, SN; Park, SY; Vidal, JL, 2020)
"Fifteen carbamazepine-responding patients with typewriter tinnitus and 8 control subjects were evaluated with a 3D T2-weighted volume isotropic turbo spin-echo acquisition sequence."3.85The Role of MRI in Diagnosing Neurovascular Compression of the Cochlear Nerve Resulting in Typewriter Tinnitus. ( Bae, YJ; Choi, BS; Jeon, YJ; Koo, JW; Song, JJ, 2017)
" The associated bilateral asynchronous clicking tinnitus responded to carbamazepine."3.76Carbamazepine responsive typewriter tinnitus from basilar invagination. ( Handzel, O; Levine, RA; Nam, EC, 2010)
"Six subjects with similar unilateral tinnitus that was fully suppressed by carbamazepine have been identified."3.73Typewriter tinnitus: a carbamazepine-responsive syndrome related to auditory nerve vascular compression. ( Levine, RA, 2006)
"A 44 year old woman presented with frequent paroxysms of unilateral tinnitus and ataxia which were abolished by treatment with carbamazepine."3.69Paroxysmal tinnitus due to a meningioma in the cerebellopontine angle. ( Ceranic, B; Espir, M; Illingworth, R; Luxon, L, 1997)
"Tinnitus is the perception of sound or noise in the absence of an external or internal acoustic stimulation."2.47Anticonvulsants for tinnitus. ( Hoekstra, CE; Rovers, MM; Rynja, SP; van Zanten, GA, 2011)
"Carbamazepine (CBZ) is a drug frequently used to treat variety of neurological diseases or symptoms."2.40Reversible pitch perception deficit due to carbamazepine. ( Imai, K; Kashihara, K; Shiro, Y; Shohmori, T, 1998)
"Recent research on the pharmacologic treatment of tinnitus is reviewed, emphasizing studies in which controls have been used."2.38Review of pharmacologic treatment of tinnitus. ( Harker, LA; Murai, K; Stouffer, JL; Tyler, RS, 1992)
"To present the case of a patient with acquired deafness who experienced musical hallucinations (MH) and to conduct a review of the relevant literature."1.31Musical hallucinations and deafness: a case report and review of the literature. ( Ali, JA, 2002)
"Carbamazepine was given as the treatment."1.26Carbamazepine in the treatment of objective myoclonus tinnitus. ( Häkkinen, V; Rahko, T, 1979)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199012 (30.77)18.7374
1990's6 (15.38)18.2507
2000's8 (20.51)29.6817
2010's9 (23.08)24.3611
2020's4 (10.26)2.80

Authors

AuthorsStudies
Sehested, PC1
Zhang, Y1
Janssen, MLF1
Gommer, ED1
Zhang, Q2
van de Berg, R1
Han, JS1
Park, JM1
Park, SY1
Vidal, JL1
Ashaikh, HK1
Kim, DK1
Park, SN1
Koo, YJ1
Kim, HJ1
Choi, JY1
Kim, JS1
Bae, YJ2
Jeon, YJ2
Choi, BS1
Koo, JW2
Song, JJ2
Sunwoo, W1
Jang, JH1
Chang, TP1
Wu, YC1
Hsu, YC1
Urban, PP1
Brüning, R1
She, W2
Dai, Y2
Du, X2
Chen, F2
Jiang, P1
Cui, X2
Kong, X1
Ma, F1
Xin, Y1
Zhao, Y1
Li, N1
Ding, X1
Brantberg, K1
De Ridder, D1
Nam, EC1
Handzel, O1
Levine, RA2
Hoekstra, CE1
Rynja, SP1
van Zanten, GA1
Rovers, MM1
Yang, HB1
Huang, DQ1
Zhu, YB1
Alpini, D1
Cesarani, A1
Giuliano, DA1
Capobianco, S1
Kanashiro, AM1
Alexandre, PL1
Pereira, CB1
Melo, AC1
Scaff, M1
Zheng, Y1
Hooton, K1
Smith, PF1
Darlington, CL1
Goodey, RJ2
Shea, JJ2
Emmett, JR1
Marks, NJ1
Onisiphorou, C1
Trounce, JR1
Donaldson, I1
Espir, M1
Illingworth, R1
Ceranic, B1
Luxon, L1
Kashihara, K1
Imai, K1
Shiro, Y1
Shohmori, T1
Sanchez, TG1
Balbani, AP1
Bittar, RS1
Bento, RF1
Câmara, J1
Yu, L1
Xu, Y1
Yu, D1
Ali, JA1
Hazell, JW1
Melding, PS1
Rahko, T1
Häkkinen, V1
Harell, M1
Murai, K1
Tyler, RS1
Harker, LA1
Stouffer, JL1
Rajah, V1
Yang, DJ1
Mardini, MK1
Hulshof, JH1
Vermeij, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Adding Lidocaine to Dexamethasone in Intra-tympanic Injection for Management of Tinnitus[NCT03265197]Phase 144 participants (Actual)Interventional2015-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for carbamazepine and Tinnitus

ArticleYear
Vestibular paroxysmia associated with typewriter tinnitus: a case report and literature review.
    Journal of neurology, 2021, Volume: 268, Issue:6

    Topics: Carbamazepine; Humans; Tinnitus; Vertigo; Vestibule, Labyrinth

2021
Vestibular paroxysmia associated with paroxysmal pulsatile tinnitus: a case report and review of the literature.
    Acta neurologica Taiwanica, 2013, Volume: 22, Issue:2

    Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobu

2013
Anticonvulsants for tinnitus.
    The Cochrane database of systematic reviews, 2011, Jul-06, Issue:7

    Topics: Administration, Oral; Amines; Anticonvulsants; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic

2011
Reversible pitch perception deficit due to carbamazepine.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:9

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Female; Hea

1998
Tinnitus.
    British journal of hospital medicine, 1979, Volume: 22, Issue:5

    Topics: Aspirin; Carbamazepine; Ear Diseases; Electric Stimulation Therapy; Hearing Loss, Noise-Induced; Hum

1979
Review of pharmacologic treatment of tinnitus.
    The American journal of otology, 1992, Volume: 13, Issue:5

    Topics: Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Double-Blind Method; Female; Flunarizine

1992

Trials

8 trials available for carbamazepine and Tinnitus

ArticleYear
[A short term study on the efficacies of intratympanic prednisolone and dexamethasone injection for subjective tinnitus].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2008, Volume: 22, Issue:19

    Topics: Adolescent; Adult; Aged; Carbamazepine; Dexamethasone; Drug Administration Routes; Female; Humans; M

2008
[Efficacy of carbamazepine combined with flunarizine hydrochloride for treating tinnitus].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2008, Volume: 22, Issue:22

    Topics: Adolescent; Adult; Aged; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Flunarizine;

2008
Treatment of subjective tinnitus: a comparative clinical study of intratympanic steroid injection vs. oral carbamazepine.
    Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:6

    Topics: Administration, Oral; Age Distribution; Anticonvulsants; Carbamazepine; Dexamethasone; Drug Administ

2009
The effect of single doses of amylobarbitone sodium and carbamazepine in tinnitus.
    The Journal of laryngology and otology, 1981, Volume: 95, Issue:9

    Topics: Amobarbital; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Humans; Tinnitus

1981
Tegretol: a double blind trial in tinnitus.
    The Journal of laryngology and otology, 1981, Volume: 95, Issue:9

    Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged;

1981
Lidocaine test in patients with tinnitus: rationale of accomplishment and relation to the treatment with carbamazepine.
    Auris, nasus, larynx, 1999, Volume: 26, Issue:4

    Topics: Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Local; Carbamazepine; Fema

1999
[Tinnitus treated with combined traditional Chinese medicine and Western medicine].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1989, Volume: 9, Issue:5

    Topics: Adult; Audiometry, Evoked Response; Carbamazepine; Drugs, Chinese Herbal; Evoked Potentials, Auditor

1989
The value of carbamazepine in the treatment of tinnitus.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1985, Volume: 47, Issue:5

    Topics: Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Humans; Lidocaine; Middle

1985

Other Studies

25 other studies available for carbamazepine and Tinnitus

ArticleYear
[Typewriter tinnitus treated with gabapentin].
    Ugeskrift for laeger, 2022, 08-15, Volume: 184, Issue:33

    Topics: Adult; Carbamazepine; Female; Gabapentin; Humans; Nerve Compression Syndromes; Tinnitus; Vertigo

2022
Typewriter tinnitus with time-locked vestibular paroxysmia in a patient with cerebellopontine angle meningioma.
    Journal of neurology, 2023, Volume: 270, Issue:11

    Topics: Carbamazepine; Cerebellar Neoplasms; Cerebellopontine Angle; Humans; Magnetic Resonance Imaging; Men

2023
Typewriter tinnitus: An investigative comparison with middle ear myoclonic tinnitus and its long-term therapeutic response to carbamazepine.
    Auris, nasus, larynx, 2020, Volume: 47, Issue:4

    Topics: Adult; Aged; Anticonvulsants; Audiometry, Pure-Tone; Carbamazepine; Dizziness; Ear, Middle; Early Me

2020
The Role of MRI in Diagnosing Neurovascular Compression of the Cochlear Nerve Resulting in Typewriter Tinnitus.
    AJNR. American journal of neuroradiology, 2017, Volume: 38, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Carbamazepine; Cerebellopontine Angle; Coc

2017
Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues.
    Scientific reports, 2017, 09-06, Volume: 7, Issue:1

    Topics: Adult; Aged; Carbamazepine; Female; Hearing Tests; Humans; Magnetic Resonance Imaging; Male; Middle

2017
[Vestibular paroxysmia and paroxysmal tinnitus].
    Der Nervenarzt, 2018, Volume: 89, Issue:2

    Topics: Aged; Analgesics, Non-Narcotic; Carbamazepine; Female; Humans; Tinnitus; Treatment Outcome; Vestibul

2018
Paroxysmal staccato tinnitus: a carbamazepine responsive hyperactivity dysfunction symptom of the eighth cranial nerve.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:4

    Topics: Aged, 80 and over; Anticonvulsants; Carbamazepine; Cochlear Nerve; Electromyography; Evoked Potentia

2010
Auditory nerve compression: a forgotten treatable cause for tinnitus.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Cochlear Nerve; Humans; Nerve Compression Syndromes; Tinnitus

2010
Carbamazepine responsive typewriter tinnitus from basilar invagination.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:4

    Topics: Adult; Anticonvulsants; Basilar Artery; Carbamazepine; Drug Administration Schedule; Hearing Loss, S

2010
[Carbamazepine caused severe drug eruption in treatment of tinnitus].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2012, Volume: 47, Issue:3

    Topics: Adult; Carbamazepine; Drug Eruptions; Female; Humans; Tinnitus

2012
Tinnitus: pharmacological topodiagnosis.
    The international tinnitus journal, 2004, Volume: 10, Issue:1

    Topics: Amantadine; Anticonvulsants; Audiometry; Auditory Perception; Carbamazepine; Diuretics; Furosemide;

2004
[Vestibular paroxysmia: clinical study and treatment of eight patients].
    Arquivos de neuro-psiquiatria, 2005, Volume: 63, Issue:3A

    Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma

2005
Typewriter tinnitus: a carbamazepine-responsive syndrome related to auditory nerve vascular compression.
    ORL; journal for oto-rhino-laryngology and its related specialties, 2006, Volume: 68, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carbamazepine; Cochlear Nerve; Decompression, Surgical; Female; Huma

2006
Carbamazepine reduces the behavioural manifestations of tinnitus following salicylate treatment in rats.
    Acta oto-laryngologica, 2008, Volume: 128, Issue:1

    Topics: Acoustic Stimulation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Association

2008
Drugs in the treatment of tinnitus.
    Ciba Foundation symposium, 1981, Volume: 85

    Topics: Amobarbital; Antidepressive Agents, Tricyclic; Carbamazepine; Ethanol; Humans; Lidocaine; Phenytoin;

1981
The medical treatment of tinnitus.
    The Journal of laryngology and otology. Supplement, 1981, Issue:4

    Topics: Adult; Carbamazepine; Diethylcarbamazine; Female; Humans; Lidocaine; Myoclonus; Phenytoin; Primidone

1981
Paroxysmal tinnitus due to a meningioma in the cerebellopontine angle.
    Journal of neurology, neurosurgery, and psychiatry, 1997, Volume: 62, Issue:4

    Topics: Analgesics, Non-Narcotic; Carbamazepine; Cerebellar Neoplasms; Cerebellopontine Angle; Combined Moda

1997
[The diagnosis and therapy of tinnitus].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 1998, Volume: 12, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Central Nervous System Depressants; Female; Humans; Male; Tinnitus

1998
Musical hallucinations and deafness: a case report and review of the literature.
    Neuropsychiatry, neuropsychology, and behavioral neurology, 2002, Volume: 15, Issue:1

    Topics: Adult; Carbamazepine; Comorbidity; Deafness; Drug Therapy, Combination; Fluvoxamine; Hallucinations;

2002
The treatment of tinnitus with oral anticonvulsants.
    The Journal of laryngology and otology, 1979, Volume: 93, Issue:2

    Topics: Administration, Oral; Adult; Aged; Carbamazepine; Female; Humans; Lidocaine; Male; Middle Aged; Phen

1979
Carbamazepine in the treatment of objective myoclonus tinnitus.
    The Journal of laryngology and otology, 1979, Volume: 93, Issue:2

    Topics: Adult; Carbamazepine; Female; Humans; Male; Myoclonus; Palatal Muscles; Tinnitus

1979
Treatment of tinnitus.
    British medical journal, 1979, Jun-02, Volume: 1, Issue:6176

    Topics: Carbamazepine; Humans; Labyrinth Diseases; Organ of Corti; Tinnitus

1979
Management of tinnitus aurium with lidocaine and carbamazepine.
    The Laryngoscope, 1978, Volume: 88, Issue:9 Pt 1

    Topics: Administration, Oral; Adult; Aged; Carbamazepine; Drug Evaluation; Female; Humans; Injections, Intra

1978
Tinnitus related to eyelid blinking.
    The Journal of laryngology and otology, 1992, Volume: 106, Issue:1

    Topics: Adult; Blinking; Carbamazepine; Female; Humans; Tinnitus; Tympanic Membrane; Uvula

1992
Ear-clicking "tinnitus" responding to carbamazepine.
    The New England journal of medicine, 1987, Dec-10, Volume: 317, Issue:24

    Topics: Adult; Carbamazepine; Humans; Male; Tinnitus

1987