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carbamazepine and Thrombocytopenia

carbamazepine has been researched along with Thrombocytopenia in 40 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Thrombocytopenia: A subnormal level of BLOOD PLATELETS.

Research Excerpts

ExcerptRelevanceReference
"To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia."7.74The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. ( Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG, 2007)
"It is not known whether polytherapy with carbamazepine (CBZ) and valproate (VPA) increases the risk of thrombocytopenia."7.71Severe, isolated thrombocytopenia under polytherapy with carbamazepine and valproate. ( Finsterer, J; Hess, B; Pelzl, G, 2001)
"The case of a patient who developed thrombocytopenia during treatment with carbamazepine (CBZ) is described."7.69Carbamazepine-induced thrombocytopenia and carbamazepine-10,11-epoxide: a case report. ( Kimura, M; Maeoka, Y; Suzuki, N; Yoshino, K, 1995)
"A rare case of carbamazepine-induced leucopenia and thrombocytopenia complicated by Henoch-Schönlein purpura (HSP) symptoms is presented."7.68Carbamazepine-induced thrombocytopenia and leucopenia complicated by Henoch-Schönlein purpura symptoms. ( Igarashi, J; Ishimoto, K; Kaneko, K; Niijima, S; Suzuki, Y; Yabuta, K, 1993)
"A case of carbamazepine-induced thrombocytopenia is reported."7.68Carbamazepine (Tegretol)-induced thrombocytopenia. ( Brenner, B; Klein, E; Shechter, Y; Tatarsky, I, 1993)
"Carbamazepine is increasingly being used in the acute and maintenance treatment of patients with bipolar disorder."7.68Thrombocytopenia associated with carbamazepine: a case series. ( Castillo, J; Cole, JO; de los Heros, R; Farrer, RJ; Miller, MG; Tohen, M, 1991)
"A case of thrombocytopenia associated with carbamazepine use is reported, and previous reports of adverse hematologic effects in patients taking carbamazepine are discussed."7.67Thrombocytopenia associated with carbamazepine: case report and review. ( Baciewicz, G; Yerevanian, BI, 1984)
"Carbamazepine is an anticonvulsant agent that has been found clinically useful in the treatment of refractory seizure disorders."5.27Carbamazepine-induced thrombocytopenia, rash, and hepatic dysfunction. ( Ponte, CD, 1983)
"Carbamazepine is an antiepileptic drug used in the treatment of epilepsy, trigeminal neuralgia, and bipolar disorder."4.31Acute lymphocytic leukemia in a patient with long-term carbamazepine exposure: Acute lymphoblastic leukemia that develops in a patient who has been using carbamazepine for a long time. ( Bagci, M; Sayin, S, 2023)
"To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia."3.74The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. ( Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG, 2007)
"It is not known whether polytherapy with carbamazepine (CBZ) and valproate (VPA) increases the risk of thrombocytopenia."3.71Severe, isolated thrombocytopenia under polytherapy with carbamazepine and valproate. ( Finsterer, J; Hess, B; Pelzl, G, 2001)
"The purpose of this study was to determine the occurrence of leukopenia and other blood dyscrasias associated with psychiatric use of carbamazepine and valproate."3.69Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk. ( Baldessarini, RJ; Castillo, J; Kando, JC; Tohen, M; Zarate, C, 1995)
"The case of a patient who developed thrombocytopenia during treatment with carbamazepine (CBZ) is described."3.69Carbamazepine-induced thrombocytopenia and carbamazepine-10,11-epoxide: a case report. ( Kimura, M; Maeoka, Y; Suzuki, N; Yoshino, K, 1995)
"A rare case of carbamazepine-induced leucopenia and thrombocytopenia complicated by Henoch-Schönlein purpura (HSP) symptoms is presented."3.68Carbamazepine-induced thrombocytopenia and leucopenia complicated by Henoch-Schönlein purpura symptoms. ( Igarashi, J; Ishimoto, K; Kaneko, K; Niijima, S; Suzuki, Y; Yabuta, K, 1993)
"A case of carbamazepine-induced thrombocytopenia is reported."3.68Carbamazepine (Tegretol)-induced thrombocytopenia. ( Brenner, B; Klein, E; Shechter, Y; Tatarsky, I, 1993)
"Carbamazepine is increasingly being used in the acute and maintenance treatment of patients with bipolar disorder."3.68Thrombocytopenia associated with carbamazepine: a case series. ( Castillo, J; Cole, JO; de los Heros, R; Farrer, RJ; Miller, MG; Tohen, M, 1991)
"A case of thrombocytopenia associated with carbamazepine use is reported, and previous reports of adverse hematologic effects in patients taking carbamazepine are discussed."3.67Thrombocytopenia associated with carbamazepine: case report and review. ( Baciewicz, G; Yerevanian, BI, 1984)
"Rare, serious adverse effects of antiepileptic drugs (AEDs) include hepatotoxicity and bone marrow suppression."2.38Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy. ( Wyllie, E; Wyllie, R, 1991)
"Carbamazepine is an anticonvulsant agent that has been found clinically useful in the treatment of refractory seizure disorders."1.27Carbamazepine-induced thrombocytopenia, rash, and hepatic dysfunction. ( Ponte, CD, 1983)
"The phenytoin was replaced by carbamazepine and the patient subsequently developed erythroid hypoplasia, neutropenia and persistent thrombocytopenia."1.27Anticonvulsant-induced marrow suppression and immune thrombocytopenia. ( Berger, S; Falk, J; Keating, A; Kelton, JG; Klein, M; McIlroy, WJ; Messner, H; Schweiger, FJ, 1988)
"Carbamazepine was found to cause statistically significant, but clinically insubstantial, decreases in white blood cell indexes."1.27Hematological effects of carbamazepine in patients with affective illness. ( Joffe, RT; Post, RM; Roy-Byrne, PP; Uhde, TW, 1985)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199015 (37.50)18.7374
1990's13 (32.50)18.2507
2000's8 (20.00)29.6817
2010's3 (7.50)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Sayin, S1
Bagci, M1
Lee, JY1
Lee, SY1
Hahm, JE1
Ha, JW1
Kim, CW1
Kim, SS1
Knobloch, K1
Busche, M1
Busch, KH1
André, MC1
Pacheco, D1
Antunes, J1
Silva, R1
Filipe, P1
Soares de Almeida, LM1
Taher, AT1
Arabi, M1
Sibai, H1
Nasreddine, W1
Otrock, ZK1
Musallam, KM1
Beydoun, A1
Cohen, Y1
Rund, D1
Moualem, E1
Kalish, Y1
Polliack, A1
Goraya, JS1
Virdi, VS1
Kumar, S1
Morozov, GV1
Semenova, NV1
Slastenko, OA1
Mishchenko, AL1
McEwen, J1
Purcell, PM1
Hill, RL1
Calcino, LJ1
Riley, CG1
Hangaishi, A1
Kurokawa, M1
Ponte, CD1
Skillrud, DM1
Goldstein, NP1
Baciewicz, G1
Yerevanian, BI1
Hoigné, R1
Kornberg, A1
Kobrin, I1
Shoenfeld, Y1
Ben Baruch, N1
Livni, E1
Santo, M1
Pinkhas, J1
Hart, RG1
Easton, JD1
Tohen, M2
Castillo, J2
Baldessarini, RJ1
Zarate, C1
Kando, JC1
Delgado, MR1
Riela, AR1
Mills, J1
Browne, R1
Roach, ES1
Terao, T1
Kaneko, K1
Igarashi, J1
Suzuki, Y1
Niijima, S1
Ishimoto, K1
Yabuta, K1
Shechter, Y1
Brenner, B1
Klein, E1
Tatarsky, I1
Kimura, M1
Yoshino, K1
Maeoka, Y1
Suzuki, N1
Ishikita, T1
Ishiguro, A1
Fujisawa, K1
Tsukimoto, I1
Shimbo, T1
Finsterer, J1
Pelzl, G1
Hess, B1
Gordon, MA1
Casasin, T1
Allende, A1
Macià, M1
Güell, R1
Wyllie, E1
Wyllie, R1
Cole, JO1
Miller, MG1
de los Heros, R1
Farrer, RJ1
Sobotka, JL1
Alexander, B1
Cook, BL1
Murray, GB1
Balon, R1
Berchou, R1
Schweiger, FJ1
Kelton, JG1
Messner, H1
Klein, M1
Berger, S1
McIlroy, WJ1
Falk, J1
Keating, A1
Drury, I1
Vanderzant, CW1
Lutz, EG1
Joffe, RT1
Post, RM1
Roy-Byrne, PP1
Uhde, TW1
Crill, WE1
Jensen, OM1

Reviews

6 reviews available for carbamazepine and Thrombocytopenia

ArticleYear
[Drug-induced thrombocytopenia].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Abciximab; Antibodies, Monoclonal; Carbamazepine; Gold Compounds; Heparin; Humans; Immunoglobulin Fa

2007
Carbamazepine-induced thrombocytopenia defined by a challenge test.
    American journal of hematology, 1999, Volume: 62, Issue:1

    Topics: Anticonvulsants; Blood Cell Count; C-Reactive Protein; Carbamazepine; Child; Conjunctiva; Eosinophil

1999
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
    Epilepsia, 1991, Volume: 32 Suppl 5

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monit

1991
A review of carbamazepine's hematologic reactions and monitoring recommendations.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:12

    Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Carbamazepine; Child, Preschool; Female; Humans; Mal

1990
Hematologic side effects of psychotropic drugs.
    Psychosomatics, 1986, Volume: 27, Issue:2

    Topics: Agranulocytosis; Anemia, Aplastic; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents;

1986
Drugs 5 years later: carbamazepine.
    Annals of internal medicine, 1973, Volume: 79, Issue:6

    Topics: Agranulocytosis; Anemia, Aplastic; Anticonvulsants; Bone Marrow; Bone Marrow Cells; Carbamazepine; D

1973

Trials

1 trial available for carbamazepine and Thrombocytopenia

ArticleYear
Thrombocytopenia secondary to high valproate levels in children with epilepsy.
    Journal of child neurology, 1994, Volume: 9, Issue:3

    Topics: Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Platelet Cou

1994

Other Studies

33 other studies available for carbamazepine and Thrombocytopenia

ArticleYear
Acute lymphocytic leukemia in a patient with long-term carbamazepine exposure: Acute lymphoblastic leukemia that develops in a patient who has been using carbamazepine for a long time.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:2

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neutropenia; Precursor Cell Lymp

2023
Clinical features of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a study of 25 patients in Korea.
    International journal of dermatology, 2017, Volume: 56, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anticonvulsants; Antitubercular Agents; Car

2017
eComment: Plasmapheresis for near-fatal heparin-induced thrombocytopenia.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 8, Issue:4

    Topics: Adult; Antibodies; Anticoagulants; Antimanic Agents; Carbamazepine; Fatal Outcome; Heparin; Humans;

2009
Generalized skin drug eruption to natalizumab in a patient with multiple sclerosis.
    Dermatology online journal, 2010, Jun-15, Volume: 16, Issue:6

    Topics: Adult; Amitriptyline; Antibodies; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzodi

2010
Carbamazepine-induced thrombocytopenia.
    Blood cells, molecules & diseases, 2012, Mar-15, Volume: 48, Issue:3

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Female; Humans; Platelet Count; Seizures; Thrombocytopen

2012
Carbamazepine-induced generalized "pseudoleukemia lymphoma"--like syndrome.
    The Israel Medical Association journal : IMAJ, 2003, Volume: 5, Issue:6

    Topics: Adult; Anticonvulsants; Biopsy; Carbamazepine; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Female

2003
Carbamazepine-induced immune thrombocytopenia.
    Neurology India, 2003, Volume: 51, Issue:1

    Topics: Anticonvulsants; Bone Marrow; Carbamazepine; Child; Humans; Male; Thrombocytopenia

2003
Anticonvulsant-hypersensitivity syndrome in a child.
    Neurology India, 2003, Volume: 51, Issue:3

    Topics: Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Thrombocytopenia

2003
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2004, Volume: 104, Issue:11

    Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine;

2004
The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An

2007
Carbamazepine-induced thrombocytopenia, rash, and hepatic dysfunction.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:9

    Topics: Adult; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Humans; Thromb

1983
Paroxysmal limb hemiataxia with crossed facial paresthesias in multiple sclerosis.
    JAMA, 1983, Nov-25, Volume: 250, Issue:20

    Topics: Adult; Ataxia; Carbamazepine; Face; Humans; Male; Multiple Sclerosis; Paresthesia; Phenytoin; Thromb

1983
Thrombocytopenia associated with carbamazepine: case report and review.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:7

    Topics: Aged; Blood Cell Count; Carbamazepine; Depressive Disorder; Female; Humans; Mood Disorders; Thromboc

1984
Drug induced immune-thrombocytopenia.
    Acta haematologica, 1982, Volume: 68, Issue:1

    Topics: Autoimmune Diseases; Carbamazepine; Humans; Oxprenolol; Thrombocytopenia

1982
IgG antiplatelet antibodies due to carbamazepine.
    Acta haematologica, 1982, Volume: 68, Issue:1

    Topics: Adolescent; Autoantibodies; Autoimmune Diseases; Blood Platelets; Carbamazepine; Humans; Immunoglobu

1982
Carbamazepine (Tegretol)-induced thrombocytopenia.
    Acta haematologica, 1982, Volume: 68, Issue:1

    Topics: Adult; Carbamazepine; Female; Humans; Thrombocytopenia

1982
Carbamazepine and hematological monitoring.
    Annals of neurology, 1982, Volume: 11, Issue:3

    Topics: Adolescent; Anemia; Anemia, Aplastic; Carbamazepine; Female; Hematologic Diseases; Humans; Leukopeni

1982
Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk.
    The American journal of psychiatry, 1995, Volume: 152, Issue:3

    Topics: Adolescent; Adult; Anemia; Carbamazepine; Depressive Disorder; Desipramine; Drug Therapy, Combinatio

1995
Transient thrombocytopenia while continuing carbamazepine.
    The American journal of psychiatry, 1993, Volume: 150, Issue:11

    Topics: Adult; Carbamazepine; Drug Monitoring; Female; Humans; Platelet Count; Thrombocytopenia

1993
Carbamazepine-induced thrombocytopenia and leucopenia complicated by Henoch-Schönlein purpura symptoms.
    European journal of pediatrics, 1993, Volume: 152, Issue:9

    Topics: Bone Marrow; Carbamazepine; Child; Depression, Chemical; Drug Hypersensitivity; Female; Humans; IgA

1993
Carbamazepine (Tegretol)-induced thrombocytopenia.
    Vox sanguinis, 1993, Volume: 65, Issue:4

    Topics: Adult; Autoantibodies; Blood Platelets; Carbamazepine; Female; Humans; Immunoglobulin G; Thrombocyto

1993
Carbamazepine-induced thrombocytopenia and carbamazepine-10,11-epoxide: a case report.
    Psychiatry and clinical neurosciences, 1995, Volume: 49, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Hemiplegia; Humans; Thrombocytopenia

1995
Severe, isolated thrombocytopenia under polytherapy with carbamazepine and valproate.
    Psychiatry and clinical neurosciences, 2001, Volume: 55, Issue:4

    Topics: Aged; Anticonvulsants; Blood Platelets; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female;

2001
Carbamazepine-associated thrombocytopenia.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:10

    Topics: Adult; Carbamazepine; Epilepsy, Complex Partial; Female; Humans; Thrombocytopenia

1992
Two episodes of carbamazepine-induced severe thrombocytopenia in the same child.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5

    Topics: Carbamazepine; Cerebral Palsy; Child; Female; Humans; Recurrence; Thrombocytopenia

1992
Thrombocytopenia associated with carbamazepine: a case series.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:12

    Topics: Adolescent; Adult; Bipolar Disorder; Carbamazepine; Female; Humans; Male; Middle Aged; Thrombocytope

1991
Carbamazepine-induced thrombocytopenia.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:4

    Topics: Alzheimer Disease; Carbamazepine; Epilepsies, Partial; Humans; Male; Middle Aged; Platelet Count; Th

1990
Anticonvulsant-induced marrow suppression and immune thrombocytopenia.
    Acta haematologica, 1988, Volume: 80, Issue:1

    Topics: Antigen-Antibody Complex; Blood Platelets; Bone Marrow; Carbamazepine; Cells, Cultured; Female; Gran

1988
Carbamazepine-induced isolated thrombocytopenia.
    The American journal of psychiatry, 1988, Volume: 145, Issue:8

    Topics: Adolescent; Carbamazepine; Humans; Male; Thrombocytopenia

1988
Carbamazepine and idiopathic thrombocytopenia.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:5

    Topics: Adult; Carbamazepine; Epilepsy, Temporal Lobe; Humans; Informed Consent; Male; Platelet Count; Throm

1985
Hematological effects of carbamazepine in patients with affective illness.
    The American journal of psychiatry, 1985, Volume: 142, Issue:10

    Topics: Adult; Anemia; Anemia, Aplastic; Bipolar Disorder; Carbamazepine; Diagnosis, Differential; Erythrocy

1985
[Thrombocytopenia after carbamazepine (Tegretol) therapy].
    Ugeskrift for laeger, 1972, Jul-03, Volume: 134, Issue:27

    Topics: Carbamazepine; Female; Humans; Middle Aged; Thrombocytopenia

1972
Carbamazepine (Tegretol).
    The Medical letter on drugs and therapeutics, 1968, Jun-28, Volume: 10, Issue:13

    Topics: Agranulocytosis; Anemia, Aplastic; Blood Platelet Disorders; Carbamazepine; Dibenzazepines; Hematolo

1968