Page last updated: 2024-10-24

carbamazepine and Stroke

carbamazepine has been researched along with Stroke in 22 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"One hundred and twenty-eight patients with poststroke seizures were randomly allocated to treatment with either levetiracetam (LEV) or sustained-release carbamazepine (CBZ) in a multicenter randomized open-label study."9.16Levetiracetam versus carbamazepine in patients with late poststroke seizures: a multicenter prospective randomized open-label study (EpIC Project). ( Bosco, D; Consoli, D; Galati, F; Neri, G; Ottonello, GA; Passarella, B; Perticoni, GF; Plastino, M; Postorino, P; Ricci, S; Toni, D, 2012)
"To assess the analgesic efficacy of carbamazepine in the treatment of chronic neuropathic pain and fibromyalgia, and to evaluate adverse events reported in the studies."8.90Carbamazepine for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; Kalso, EA; Moore, RA; Wiffen, PJ, 2014)
"Acute ataxia is commonly the chief complaint among patients visiting the emergency department (ED)."5.72A Phenytoin-Induced Ataxia Mimicking a Stroke. ( Urushidani, S, 2022)
"Levetiracetam (LEV) is an AED that is neuroprotective in various neurologic disorders."5.51Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study. ( Bao, XH; Wang, ZX; Xiong, H; Yuan, Y; Zhang, X; Zhang, Z; Zhao, DH; Zhao, XT, 2019)
"Recurrent seizures requiring either emergency room (ER) visits or hospitalization were used to measure the efficacy of seizure control."5.42Efficacy of phenytoin, valproic acid, carbamazepine and new antiepileptic drugs on control of late-onset post-stroke epilepsy in Taiwan. ( Chan, L; Chi, NF; Chien, LN; Chiou, HY; Hu, CJ; Huang, YH; Kuan, YC, 2015)
"One hundred and twenty-eight patients with poststroke seizures were randomly allocated to treatment with either levetiracetam (LEV) or sustained-release carbamazepine (CBZ) in a multicenter randomized open-label study."5.16Levetiracetam versus carbamazepine in patients with late poststroke seizures: a multicenter prospective randomized open-label study (EpIC Project). ( Bosco, D; Consoli, D; Galati, F; Neri, G; Ottonello, GA; Passarella, B; Perticoni, GF; Plastino, M; Postorino, P; Ricci, S; Toni, D, 2012)
"To assess the analgesic efficacy of carbamazepine in the treatment of chronic neuropathic pain and fibromyalgia, and to evaluate adverse events reported in the studies."4.90Carbamazepine for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; Kalso, EA; Moore, RA; Wiffen, PJ, 2014)
" In epilepsy after trauma, levetiracetam had the highest retention rate at 80% (95% confidence interval [CI] = 65-89), exceeding that of the most commonly prescribed ASM, carbamazepine (p = ."4.02Potential for improved retention rate by personalized antiseizure medication selection: A register-based analysis. ( Garcia-Ptacek, S; Håkansson, S; Karlander, M; Larsson, D; Mahamud, Z; Zelano, J; Zelezniak, A, 2021)
"Use of carbamazepine and valproic acid, but not lithium and lamotrigine, is associated with increased risk of stroke in patients with bipolar disorder."3.91Mood stabilisers and risk of stroke in bipolar disorder. ( Chang, CK; Chen, CC; Chen, PH; Kuo, CJ; Pan, CH; Su, SS; Tsai, SY, 2019)
"Lamotrigine and levetiracetam have higher retention rates than carbamazepine in poststroke epilepsy."3.91Retention rate of first antiepileptic drug in poststroke epilepsy: A nationwide study. ( Åsberg, S; Kumlien, E; Larsson, D; Zelano, J, 2019)
"This study investigated the relationship between dysgeusia and dysesthesia in stroke patients and evaluated the effect of carbamazepine therapy."3.74Relationship between dysgeusia and dysesthesia in stroke patients. ( Etoh, S; Kawahira, K; Ogata, A; Shimodozono, M; Tanaka, N, 2008)
"A 72-year-old Caucasian woman with paroxysmal atrial fibrillation had been taking warfarin therapy for 5 years with a stable international normalized ratio (INR)."3.73Effect of carbamazepine initiation and discontinuation on antithrombotic control in a patient receiving warfarin: case report and review of the literature. ( O'donnell, PJ; Parrish, RH; Pazdur, DE, 2006)
"Acute ataxia is commonly the chief complaint among patients visiting the emergency department (ED)."1.72A Phenytoin-Induced Ataxia Mimicking a Stroke. ( Urushidani, S, 2022)
"Carbamazepine was the second most common drug followed by lamotrigine and valproic acid."1.62Post-stroke epilepsy and antiepileptic drug use in men and women. ( Linnér, L; Loikas, D; Sundström, A; von Euler, M; Wettermark, B, 2021)
"Epilepsy was present in 29."1.51[Epilepsy in children with congenital hemiparesis secondary to perinatal ictus]. ( Alonso, X; Campistol, J; Escofet, C; Fons, C; Macaya, A; Revilla Orías, MD, 2019)
"Levetiracetam (LEV) is an AED that is neuroprotective in various neurologic disorders."1.51Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study. ( Bao, XH; Wang, ZX; Xiong, H; Yuan, Y; Zhang, X; Zhang, Z; Zhao, DH; Zhao, XT, 2019)
"Carbamazepine was the most chosen antiepileptic drug for secondary prophylaxis, followed by valproate acid, and levetiracetam."1.48[A nationwide multi-center questionnaire survey on the management and treatment of post-stroke seizure and epilepsy in Japan]. ( Abe, S; Fukuma, K; Higashida, K; Ihara, M; Nagatsuka, K; Okuno, Y; Tanaka, T; Tomari, S; Toyoda, K; Yamagami, H, 2018)
"Patients with trisomy 21 have an increased risk for stroke, which usually stems from cardiovascular defects."1.46Brain tuberculoma, an unusual cause of stroke in a child with trisomy 21: a case report. ( Hamed, AA; Hamid, FA; Ibrahim, SA; Kheir, AEM; Yousif, BM, 2017)
"Recurrent seizures requiring either emergency room (ER) visits or hospitalization were used to measure the efficacy of seizure control."1.42Efficacy of phenytoin, valproic acid, carbamazepine and new antiepileptic drugs on control of late-onset post-stroke epilepsy in Taiwan. ( Chan, L; Chi, NF; Chien, LN; Chiou, HY; Hu, CJ; Huang, YH; Kuan, YC, 2015)
" In addition, there appeared to be a dose-response relationship between stroke risk and PHT prescriptions."1.39Comparative stroke risk of antiepileptic drugs in patients with epilepsy. ( Hsieh, CY; Lai, EC; Lin, SJ; Yang, YH, 2013)
"We report an infant with moyamoya disease and recurrent stroke presenting 10 months after diagnosis (at age 18 months), and discuss the outcome of nonsurgical medical management."1.38Medical management of moyamoya disease and recurrent stroke in an infant with Majewski osteodysplastic primordial dwarfism type II (MOPD II). ( Alanay, Y; Boduroğlu, K; Cetin, M; Haliloğlu, G; Kılıç, E; Oğuz, KK; Unal, S; Utine, E, 2012)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (22.73)29.6817
2010's13 (59.09)24.3611
2020's4 (18.18)2.80

Authors

AuthorsStudies
Anger, T1
Madge, DJ1
Mulla, M1
Riddall, D1
Larsson, D3
Baftiu, A1
Johannessen Landmark, C1
von Euler, M2
Kumlien, E2
Åsberg, S2
Zelano, J3
Urushidani, S1
Revilla Orías, MD1
Alonso, X1
Campistol, J1
Macaya, A1
Escofet, C1
Fons, C1
Loikas, D1
Linnér, L1
Sundström, A1
Wettermark, B1
Håkansson, S1
Karlander, M1
Mahamud, Z1
Garcia-Ptacek, S1
Zelezniak, A1
Kheir, AEM1
Ibrahim, SA1
Hamed, AA1
Yousif, BM1
Hamid, FA1
Higashida, K1
Tanaka, T1
Yamagami, H1
Tomari, S1
Fukuma, K1
Okuno, Y1
Abe, S1
Nagatsuka, K1
Toyoda, K1
Ihara, M1
Chen, PH1
Tsai, SY1
Pan, CH1
Chang, CK1
Su, SS1
Chen, CC1
Kuo, CJ1
Zhang, Z1
Zhao, DH1
Zhao, XT1
Zhang, X1
Xiong, H1
Bao, XH1
Yuan, Y1
Wang, ZX1
Wiffen, PJ1
Derry, S1
Moore, RA1
Kalso, EA1
Huang, YH1
Chi, NF1
Kuan, YC1
Chan, L1
Hu, CJ1
Chiou, HY1
Chien, LN1
Janszky, J1
Horvath, R1
Komoly, S1
Mannheimer, B1
Andersson, ML1
Järnbert-Pettersson, H1
Lindh, JD1
Kılıç, E1
Utine, E1
Unal, S1
Haliloğlu, G1
Oğuz, KK1
Cetin, M1
Boduroğlu, K1
Alanay, Y1
Hsieh, CY1
Lai, EC1
Yang, YH1
Lin, SJ1
Consoli, D1
Bosco, D1
Postorino, P1
Galati, F1
Plastino, M1
Perticoni, GF1
Ottonello, GA1
Passarella, B1
Ricci, S1
Neri, G1
Toni, D1
Turazzini, M1
Manganotti, P1
Del Colle, R1
Silvestri, M1
Fiaschi, A1
Banks, MC1
Caruso, PA1
Lessell, S1
Parrish, RH1
Pazdur, DE1
O'donnell, PJ1
Etoh, S1
Kawahira, K1
Ogata, A1
Shimodozono, M1
Tanaka, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Electroacupuncture Therapy for Change of Pain in Classical Trigeminal Neuralgia[NCT03580317]120 participants (Actual)Interventional2018-07-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for carbamazepine and Stroke

ArticleYear
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Mo

2001
Carbamazepine for chronic neuropathic pain and fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2014, Apr-10, Issue:4

    Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Chronic Pain; Diabetic Neuropathies; Fibromyalgia; H

2014
[ZONISAMIDE: FIRST CHOICE AMONG THE FIRST-LINE ANTIEPILEPTIC DRUGS IN FOCAL EPILEPSY].
    Ideggyogyaszati szemle, 2015, May-30, Volume: 68, Issue:5-6

    Topics: Adolescent; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Administratio

2015

Trials

2 trials available for carbamazepine and Stroke

ArticleYear
Levetiracetam versus carbamazepine in patients with late poststroke seizures: a multicenter prospective randomized open-label study (EpIC Project).
    Cerebrovascular diseases (Basel, Switzerland), 2012, Volume: 34, Issue:4

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Female; Humans;

2012
Serum levels of carbamazepine and cortical excitability by magnetic brain stimulation.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Electric Stimulation; Electromagnetic Fields; Epilepsy,

2004

Other Studies

17 other studies available for carbamazepine and Stroke

ArticleYear
Association Between Antiseizure Drug Monotherapy and Mortality for Patients With Poststroke Epilepsy.
    JAMA neurology, 2022, 02-01, Volume: 79, Issue:2

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Cohort Studies; Dr

2022
A Phenytoin-Induced Ataxia Mimicking a Stroke.
    The American journal of emergency medicine, 2022, Volume: 60

    Topics: Ataxia; Carbamazepine; Female; Humans; Middle Aged; Phenytoin; Stroke; Valproic Acid

2022
[Epilepsy in children with congenital hemiparesis secondary to perinatal ictus].
    Medicina, 2019, Volume: 79 Suppl 3

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infan

2019
Post-stroke epilepsy and antiepileptic drug use in men and women.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 129, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigin

2021
Potential for improved retention rate by personalized antiseizure medication selection: A register-based analysis.
    Epilepsia, 2021, Volume: 62, Issue:9

    Topics: Anticonvulsants; Brain Injuries, Traumatic; Carbamazepine; Dementia; Epilepsy; Humans; Levetiracetam

2021
Brain tuberculoma, an unusual cause of stroke in a child with trisomy 21: a case report.
    Journal of medical case reports, 2017, Apr-18, Volume: 11, Issue:1

    Topics: Anti-Inflammatory Agents; Antitubercular Agents; Carbamazepine; Child; Dexamethasone; Diagnosis, Dif

2017
[A nationwide multi-center questionnaire survey on the management and treatment of post-stroke seizure and epilepsy in Japan].
    Rinsho shinkeigaku = Clinical neurology, 2018, Apr-25, Volume: 58, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Japan; Levetiracetam; Male; Piracetam; Sei

2018
Mood stabilisers and risk of stroke in bipolar disorder.
    The British journal of psychiatry : the journal of mental science, 2019, Volume: 215, Issue:1

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cross-O

2019
Retention rate of first antiepileptic drug in poststroke epilepsy: A nationwide study.
    Seizure, 2019, Volume: 64

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Leve

2019
Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study.
    Chinese medical journal, 2019, Feb-05, Volume: 132, Issue:3

    Topics: Acidosis, Lactic; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Human

2019
Efficacy of phenytoin, valproic acid, carbamazepine and new antiepileptic drugs on control of late-onset post-stroke epilepsy in Taiwan.
    European journal of neurology, 2015, Volume: 22, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Cohort Studies; Female; Humans; Male

2015
The effect of carbamazepine on warfarin anticoagulation: a register-based nationwide cohort study involving the Swedish population.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Brain Ischemia; Carbamazepine; Drug Administra

2016
Medical management of moyamoya disease and recurrent stroke in an infant with Majewski osteodysplastic primordial dwarfism type II (MOPD II).
    European journal of pediatrics, 2012, Volume: 171, Issue:10

    Topics: Antigens; Carbamazepine; Dwarfism; Female; Fetal Growth Retardation; Heparin, Low-Molecular-Weight;

2012
Comparative stroke risk of antiepileptic drugs in patients with epilepsy.
    Epilepsia, 2013, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male

2013
Midbrain-thalamic ocular neuromyotonia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Diplopia; Dizziness; Humans; Isaacs Syndrome; Magnetic Resona

2005
Effect of carbamazepine initiation and discontinuation on antithrombotic control in a patient receiving warfarin: case report and review of the literature.
    Pharmacotherapy, 2006, Volume: 26, Issue:11

    Topics: Aged; Analgesics, Non-Narcotic; Anticoagulants; Atrial Fibrillation; Carbamazepine; Drug Interaction

2006
Relationship between dysgeusia and dysesthesia in stroke patients.
    The International journal of neuroscience, 2008, Volume: 118, Issue:1

    Topics: Afferent Pathways; Aged; Analgesics, Non-Narcotic; Carbamazepine; Dysgeusia; Face; Female; Humans; M

2008