carbamazepine has been researched along with Stevens-Johnson Syndrome in 225 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to investigate the prevalence and association of HLA-B*15:02 with carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-SJS/TEN) in the Indian population in Malaysia, which mostly originated from Southern India." | 8.90 | HLA-B*15:02 association with carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in an Indian population: a pooled-data analysis and meta-analysis. ( Khor, AH; Lim, KS; Ng, CC; Tan, CT; Wong, SM, 2014) |
| "The US Food and Drug Administration recommends screening for the HLA-B*1502 allele before initiation of carbamazepine therapy in patients of Asian ancestry, but there remains unclear evidence of a relationship between HLA-B*1502 and Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) among carbamazepine users, especially in some racial/ethnic populations." | 8.89 | Relationship between the HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis. ( Chaiyakunapruk, N; Lohitnavy, M; Somkrua, R; Tangamornsuksan, W; Tassaneeyakul, W, 2013) |
| " The specific MHC molecules implicated in hypersensitivity have been identified; for example, HLA-B*5701 in abacavir-induced drug hypersensitivity and HLA-B*1502 in carbamazepine-induced Stevens-Johnson syndrome." | 8.88 | T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction. ( Chen, YT; Ko, TM, 2012) |
| ", carbamazepine (CBZ)- and lamotrigine (LTG)-induced Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN)." | 8.31 | Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study. ( Asadi-Pooya, AA; Dastgheib, L; Gharesi-Fard, B; Hadibarhaghtalab, M; Namjoo, S; Rostami, F; Tahmasebi, F, 2023) |
| "The total number of reports identified as Stevens-Johnson syndrome or toxic epidermal necrolysis associated with carbamazepine or oxcarbazepine included in this study was 1231." | 8.02 | Assessing carbamazepine and oxcarbazepine-associated Stevens-Johnson syndrome/toxic epidermal necrolysis: Data mining the public version of the FDA adverse event reporting system. ( Fang, W; Pan, L; Sun, Q; Xu, C; Zhang, J; Zhang, Y, 2021) |
| "We constructed a Markov model in a hypothetical cohort of adult Asian patients with epilepsy in the United States being considered for carbamazepine to investigate the cost-effectiveness of two alternative strategies: (1) no HLA-B*1502 gene allele screening and using carbamazepine and (2) HLA-B*1502 gene allele screening and starting levetiracetam in the case of a positive screen." | 7.91 | Cost-effectiveness of screening for HLA-B*1502 prior to initiation of carbamazepine in epilepsy patients of Asian ancestry in the United States. ( Choi, H; Mohit, B, 2019) |
| "The goal of our study was to investigate the incidence of Stevens-Johnson syndrome (SJS), the frequency of SJS diagnosis, and the association between SJS and prior use of allopurinol, carbamazepine or phenytoin." | 7.88 | Incidence of Stevens-Johnson syndrome following combination drug use of allopurinol, carbamazepine and phenytoin in Taiwan: A case-control study. ( Cheng, CY; Cheng, FJ; Chuang, PC; Huang, YS; Pan, HY; Syu, FK, 2018) |
| "Phenytoin (PHE) and carbamazepine (CBZ) are first rank causative drugs that can induce drug rash with eosinophilia and systemic symptoms (DRESS) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)." | 7.88 | Evaluation of a lymphocyte transformation test and cytokine detection assay to identify phenytoin and carbamazepine provoked DRESS or SJS/TEN in epilepsy patients. ( Kumkamthornkul, P; Srinoulprasert, Y; Tansit, T; Tuchinda, P; Udnaen, S, 2018) |
| "HLA-B*15:02 screening before carbamazepine (CBZ) prescription in Asian populations is the recommended practice to prevent CBZ-induced Stevens-Johnson syndrome (CBZ-SJS)." | 7.85 | HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis. ( Jaruthamsophon, K; Limprasert, P; Sangiemchoey, A; Sukasem, C; Tipmanee, V, 2017) |
| "The majority of the carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis CBZ-SJS/TEN are associated with HLA-B*15:02 in Asian populations where this allele is common." | 7.85 | HLA-A*31: 01 and HLA-B*15:02 association with Stevens-Johnson syndrome and toxic epidermal necrolysis to carbamazepine in a multiethnic Malaysian population. ( Khor, AH; Kwan, Z; Lim, KS; Ng, CC; Tan, CT; Tan, WC; Wu, DB, 2017) |
| "Carbamazepine (CBZ) is a common cause of life-threatening cutaneous adverse drug reactions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 7.85 | Association of the HLA-B alleles with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in the Javanese and Sundanese population of Indonesia: the important role of the HLA-B75 serotype. ( Cavallari, LH; Kristin, E; Mahasirimongkol, S; Menaldi, SL; Prayuni, K; Sachrowardi, Q; Suyatna, FD; Wichukchinda, N; Yuliwulandari, R, 2017) |
| "Stevens-Johnson syndrome/toxic epidermal necrolysis after initiation of carbamazepine in a HLA-B*15:02 gene carrier - screening in risk patients is recommended A 32-year-old woman, adopted from Indonesia, developed Stevens-Johnsons syndrome (SJS)/toxic epidermal necrolysis (TEN) after initiating carbamazepine treatment for epilepsy." | 7.85 | [Stevens-Johnson syndrome/toxic epidermal necrolysis after initiation of carbamazepine in a HLA-B*15:02 gene carrier – screening in risk patients is recommended]. ( Anastasopoulou, S; Karlsson, M; Komuda, M; Presman, B; Tomson, T, 2017) |
| " A portion of such reactions is observed to strongly associate with certain human leukocyte antigen (HLA) alleles; one of the strongest associations is the HLA-B*1502 protein with carbamazepine (CBZ)-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) - the odds ratio value can even be higher than one thousand." | 7.83 | Structural modeling of HLA-B*1502/peptide/carbamazepine/T-cell receptor complex architecture: implication for the molecular mechanism of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. ( Huang, J; Wang, Y; Yang, C; Zhang, S; Zhou, P, 2016) |
| "The HLA-B*15:02 allele is a risk factor for carbamazepine (CBZ)-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in populations where the allele is prevalent." | 7.83 | The HLA-B*15:02 allele in a Spanish Romani patient with carbamazepine-induced Stevens-Johnson syndrome. ( Aramburu, JA; Bellón, T; Borobia, AM; de Abajo, FJ; González-Herrada, C; Laosa, O; Lerma, V; Moreno-Hidalgo, MA; Ramírez, E, 2016) |
| "Screening for the HLA-B*15:02 allele has been recommended to prevent carbamazepine (CBZ) - induced Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) in individuals with Asian ancestry." | 7.83 | Validation of a novel real-time PCR assay for detection of HLA-B*15:02 allele for prevention of carbamazepine - Induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis in individuals of Asian ancestry. ( Chu, HC; Do, NT; Fernando, SL; Fulton, RB; Le, HT; Li, J; Nguyen, DV; Tran, TT; Vidal, C, 2016) |
| "This study explored the association between the risk of carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and CBZ dose, dose-adjusted concentration, and ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms in patients of Han ethnicity with epilepsy who were living in northeastern China." | 7.80 | Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy. ( He, XJ; He, XL; Jian, LY; Sun, XJ; Tang, M; Wu, Y; Xu, YY; Zhao, LM, 2014) |
| "This study examined the significant association between carbamazepine (CBZ)-induced Stevens-Johnson Syndrome (SJS)/toxic epidermal necrolysis (TEN) and HLA-B*15:02 in epilepsy patients of Han ethnicity living in northeastern China." | 7.79 | Association between the HLA-B*15:02 allele and carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Han individuals of northeastern China. ( He, XJ; He, XL; Jian, LY; Miao, LY; Sun, XJ; Wu, Y; Xu, YY; Zhao, LM, 2013) |
| "We adopted the HLA-B∗1502 genetic predisposition to carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) as a model to study the pathologic role of HLA in delayed-type drug hypersensitivity." | 7.78 | Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome. ( Chen, YT; Chung, WH; Huang, HW; Hung, SI; Wei, CY, 2012) |
| "Previous studies have demonstrated a strong association between carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-induced SJS/TEN) and HLA-B*1502 in Chinese, and HLA-A*3101 but not HLA-B*1502 in Caucasians and Japanese." | 7.78 | Association between HLA and Stevens-Johnson syndrome induced by carbamazepine in Southern Han Chinese: genetic markers besides B*1502? ( Gao, MM; Liao, WP; Liu, XR; Min, FL; Qin, B; Shi, YW; Wang, Q; Zhou, JQ; Zou, X, 2012) |
| "Carbamazepine (CBZ), a frequently used anticonvulsant drug, is one of the most common causes of life-threatening cutaneous adverse drug reactions such as toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS)." | 7.77 | Association of HLA-B*1502 allele with carbamazepine-induced toxic epidermal necrolysis and Stevens-Johnson syndrome in the multi-ethnic Malaysian population. ( Chang, CC; Hussein, SH; Murad, S; Too, CL, 2011) |
| "We describe the association of the HLA-B*1502 allele in 27 epilepsy patients (19 Malays, 8 Chinese) treated with carbamazepine (CBZ) at the UKM Medical Center (UKMMC), 6 with CBZ-Steven Johnson Syndrome (CBZ-SJS), 11 with CBZ-induced rash, 2 with suspected phenytoin-induced rash and 8 negative controls." | 7.77 | Frequency of the HLA-B*1502 allele contributing to carbamazepine-induced hypersensitivity reactions in a cohort of Malaysian epilepsy patients. ( Jamal, R; Rani, ZZ; Ratnaningrum, S; Raymond, AA; Then, SM, 2011) |
| "Although carbamazepine (CBZ) is the most common cause of Stevens-Johnson syndrome (SJS), a new anticonvulsant, oxcarbazepine, which is structurally related to carbamazepine, has been shown to induce SJS, although extremely rarely." | 7.75 | Oxcarbazepine-induced Stevens-Johnson syndrome: a case report. ( Lai, PC; Lin, LC; Yang, RC; Yang, SF, 2009) |
| "Previous studies found a strong association between HLA-B*1502 and carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) in Han Chinese, but not in Caucasian populations." | 7.74 | Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population. ( Desudchit, T; Hirankarn, N; Kangwanshiratada, O; Korkij, W; Limotai, C; Locharernkul, C; Loplumlert, J; Shotelersuk, V; Suphapeetiporn, K; Tongkobpetch, S, 2008) |
| "This study investigated the association between 2 mood stabilizers (carbamazepine and valproate) and other medications (including other anticonvulsants) and the risks of erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) among patients with bipolar disorder." | 7.74 | The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study. ( Chang, CJ; Chao, PF; Gau, CS; Gau, SS; Lin, YJ, 2008) |
| "Two patients with psychotic disorders who developed Stevens-Johnson Syndrome while on treatment with carbamazepine is reported due to its rarity." | 7.70 | Stevens-Johnson syndrome due to carbamazepine. ( Chaudhury, S; John, TR; Ramadasan, P; Vaishampayne, S, 2000) |
| "Three cases of Stevens-Johnson Syndrome developing after the addition of Carbamazepine to existing neuroleptic medication are described." | 7.68 | Stevens-Johnson syndrome in neuroleptic-carbamazepine combination. ( Wong, KE, 1990) |
| "Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute life-threatening mucocutaneous drug reactions." | 6.72 | Carbamazepine-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review. ( Al Abri, AM; Al Rajaibi, R; Al Rumhi, T, 2021) |
| "Lamotrigine is an antiepileptic drug of the phenyltriazine class that is indicated for the prevention of focal and generalized seizures in epileptic patients as well as monotherapy or adjunctive maintenance treatment for Bipolar disorder." | 6.72 | Lamotrigine and Stevens-Johnson Syndrome Prevention. ( Crane, E; Edinoff, AN; Fitz-Gerald, MJ; Gennuso, SA; Kaye, AD; Kaye, AM; Kaye, JS; Kaye, RJ; Lewis, K; Nguyen, LH; Pierre, SS; Urits, I; Varrassi, G; Viswanath, O, 2021) |
| "Carbamazepine (CBZ) is an FDA-approved anticonvulsant that is widely used to treat epilepsy, bipolar disorder, trigeminal neuralgia and chronic pain." | 5.72 | Development of label-free electrochemical impedance spectroscopy for the detection of HLA-B*15:02 and HLA-B*15:21 for the prevention of carbamazepine-induced Stevens-Johnson syndrome. ( Attapong, J; Chomean, S; Kaset, C; Nakkam, N; Tassaneeyakul, W, 2022) |
| "Levetiracetam is an increasingly used new non-aromatic antiepileptic drug and reported to have a better safety profile in daily practice." | 5.62 | Anaphylaxis to levetiracetam in an adolescent: a very rare occurence. ( Arhan, E; Bakırtaş, A; Değermenci, Ş; Ertoy-Karagöl, Hİ; Güleryüz, OD; Kahraman, Ş; Menderes, D; Oktay, MA, 2021) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening severe cutaneous adverse reactions." | 5.36 | HLA-B*1511 is a risk factor for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients. ( Abe, M; Aihara, M; Furuya, H; Hasegawa, R; Ikeda, H; Ikezawa, Z; Kaniwa, N; Kashiwagi, M; Kinoshita, S; Kurose, K; Matsunaga, K; Muramatsu, M; Saito, Y; Song, Y; Sotozono, C; Takahashi, Y; Tohkin, M; Ueta, M, 2010) |
| "Acute generalised exanthematous pustulosis and Stevens-Johnson syndrome (toxic epidermal necrolysis spectrum of severe cutaneous drug reactions) are believed to have distinct underlying pathophysiologies." | 5.35 | Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine. ( Goh, SG; Goh, TK; Pang, SM; Thirumoorthy, T, 2008) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can involve MHC-restricted presentation of a drug or its metabolites for T-cell activation." | 5.34 | HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome. ( Chen, ST; Chen, YT; Fang, WH; Hung, SI; Juo, CG; Lin, YP; Lu, IH; Yang, CW, 2007) |
| "Heroin and alcohol abuse alters host immunity which subsequently may increase susceptibility to allergic reactions." | 5.30 | [Stevens-Johnson syndrome with transition to toxic epidermal necrolysis after carbamazepine administration, heroin and alcohol abuse]. ( Haustein, UF; Petter, G, 1999) |
| " The associations between abacavir hypersensitivity and HLA-B*57:01 and carbamazepine-induced Stevens-Johnson syndrome and HLA-B*15:02 have been implemented in clinical practice." | 4.91 | New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity. ( Ostrov, DA; Park, BK; Pirmohamed, M, 2015) |
| "This study aimed to investigate the prevalence and association of HLA-B*15:02 with carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-SJS/TEN) in the Indian population in Malaysia, which mostly originated from Southern India." | 4.90 | HLA-B*15:02 association with carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in an Indian population: a pooled-data analysis and meta-analysis. ( Khor, AH; Lim, KS; Ng, CC; Tan, CT; Wong, SM, 2014) |
| " As for SCARs, associations of HLA-B*15:02 or HLA-A*31:01 and HLA-B*58:01 have been revealed for carbamazepine- and allopurinol-related Stevens-Johnson syndrome and toxic epidermal neclolysis, respectively." | 4.89 | Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury. ( Kaniwa, N; Saito, Y, 2013) |
| "The US Food and Drug Administration recommends screening for the HLA-B*1502 allele before initiation of carbamazepine therapy in patients of Asian ancestry, but there remains unclear evidence of a relationship between HLA-B*1502 and Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) among carbamazepine users, especially in some racial/ethnic populations." | 4.89 | Relationship between the HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis. ( Chaiyakunapruk, N; Lohitnavy, M; Somkrua, R; Tangamornsuksan, W; Tassaneeyakul, W, 2013) |
| " The specific MHC molecules implicated in hypersensitivity have been identified; for example, HLA-B*5701 in abacavir-induced drug hypersensitivity and HLA-B*1502 in carbamazepine-induced Stevens-Johnson syndrome." | 4.88 | T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction. ( Chen, YT; Ko, TM, 2012) |
| "Recent studies associated the HLA-B 1502 allele with carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) in patients from China, Thailand and Malaysia." | 4.87 | Pharmacogenetic screening of carbamazepine-induced severe cutaneous allergic reactions. ( Hirankarn, N; Locharernkul, C; Shotelersuk, V, 2011) |
| " A strong genetic association between HLA-B*1502 and carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) has been shown in Han Chinese patients." | 4.86 | Genetic predisposition of life-threatening antiepileptic-induced skin reactions. ( Chen, YT; Chung, WH; Hung, SI, 2010) |
| "Extensive scientific evidence consistently demonstrates the clinical validity and utility of HLA-B*15:02 pre-screening in averting severe cutaneous adverse reactions (SCARs), namely Stevens-Johnson syndrome and toxic epidermal necrolysis, associated with carbamazepine or oxcarbazepine usage." | 4.84 | Pharmacogenetics to prevent hypersensitivity reactions to antiepileptic drugs: is testing performed when indicated? ( Alvarez-Arango, S; Bui, VL; Stevenson, JM, 2024) |
| " The genetic associations can be drug specific, such as HLA-B*1502 being associated with carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN), HLA-B*5701 with abacavir hypersensitivity and HLA-B*5801 with allopurinol-induced severe cutaneous adverse reactions." | 4.84 | Human leukocyte antigens and drug hypersensitivity. ( Chen, YT; Chung, WH; Hung, SI, 2007) |
| ", carbamazepine (CBZ)- and lamotrigine (LTG)-induced Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN)." | 4.31 | Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study. ( Asadi-Pooya, AA; Dastgheib, L; Gharesi-Fard, B; Hadibarhaghtalab, M; Namjoo, S; Rostami, F; Tahmasebi, F, 2023) |
| "Carbamazepine (CBZ) is an aromatic anticonvulsant known to cause drug hypersensitivity reactions, which range in severity from relatively mild maculopapular exanthema to potentially fatal Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN)." | 4.31 | Characterization of Drug-Specific CD4 ( Alfirevic, A; Hammond, S; Jaruthamsophon, K; Naisbitt, DJ; Pirmohamed, M; Sukasem, C; Thomson, PJ; Zhang, E, 2023) |
| "Carbamazepine (CBZ)-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are strongly associated with the HLA-B*15:02 allele." | 4.02 | Cost-effectiveness analysis of genotyping for HLA-B*15:02 in Indonesian patients with epilepsy using a generic model. ( Cavallari, LH; Hao, J; Kristin, E; Mahasirimongkol, S; Mitropoulou, C; Patrinos, GP; Prahasto, ID; Prayuni, K; Shin, JG; Snyder, SR; Suyatna, FD; Williams, MS; Yuliwulandari, R, 2021) |
| "The total number of reports identified as Stevens-Johnson syndrome or toxic epidermal necrolysis associated with carbamazepine or oxcarbazepine included in this study was 1231." | 4.02 | Assessing carbamazepine and oxcarbazepine-associated Stevens-Johnson syndrome/toxic epidermal necrolysis: Data mining the public version of the FDA adverse event reporting system. ( Fang, W; Pan, L; Sun, Q; Xu, C; Zhang, J; Zhang, Y, 2021) |
| " Carbamazepine- or oxcarbazepine-induced maculopapular exanthema occurred earlier (median: one week) than that induced by other antiseizure medications (median: three weeks) (p=0." | 4.02 | Cutaneous adverse reactions associated with antiseizure medication: clinical characteristics and implications in epilepsy treatment. ( Bettinotti, MP; Braatz, VL; de Paola, L; Iglehart, B; Lohr, A; Rodrigues, M; Silvado, CES; Tensini, FS; Tensini, TS; Von Glehn, CQC, 2021) |
| "We constructed a Markov model in a hypothetical cohort of adult Asian patients with epilepsy in the United States being considered for carbamazepine to investigate the cost-effectiveness of two alternative strategies: (1) no HLA-B*1502 gene allele screening and using carbamazepine and (2) HLA-B*1502 gene allele screening and starting levetiracetam in the case of a positive screen." | 3.91 | Cost-effectiveness of screening for HLA-B*1502 prior to initiation of carbamazepine in epilepsy patients of Asian ancestry in the United States. ( Choi, H; Mohit, B, 2019) |
| "Due to the significant risk of developing Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), the use of carbamazepine is not recommended in patients carrying the human leukocyte antigen B (HLA-B) *15:02 allele." | 3.88 | External quality assessment for laboratory testing of HLA-B*15:02 allele in relation to carbamazepine therapy. ( Han, Y; Li, J; Lin, G; Xie, J; Zhang, K, 2018) |
| "The presence of HLA-B*15:02 allele is considered a risk factor for development of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in patients taking aromatic anticonvulsant drugs like carbamazepine and phenytoin." | 3.88 | The association of HLA B*15:02 allele and Stevens-Johnson syndrome/toxic epidermal necrolysis induced by aromatic anticonvulsant drugs in a South Indian population. ( Devi, K, 2018) |
| "The goal of our study was to investigate the incidence of Stevens-Johnson syndrome (SJS), the frequency of SJS diagnosis, and the association between SJS and prior use of allopurinol, carbamazepine or phenytoin." | 3.88 | Incidence of Stevens-Johnson syndrome following combination drug use of allopurinol, carbamazepine and phenytoin in Taiwan: A case-control study. ( Cheng, CY; Cheng, FJ; Chuang, PC; Huang, YS; Pan, HY; Syu, FK, 2018) |
| "Phenytoin (PHE) and carbamazepine (CBZ) are first rank causative drugs that can induce drug rash with eosinophilia and systemic symptoms (DRESS) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)." | 3.88 | Evaluation of a lymphocyte transformation test and cytokine detection assay to identify phenytoin and carbamazepine provoked DRESS or SJS/TEN in epilepsy patients. ( Kumkamthornkul, P; Srinoulprasert, Y; Tansit, T; Tuchinda, P; Udnaen, S, 2018) |
| "A hybrid model of a decision tree and Markov model was developed to evaluate three strategies for treating newly diagnosed epilepsy among adults: (i) carbamazepine initiation without HLA-B*15:02 screening (current practice); (ii) universal HLA-B*15:02 screening prior to carbamazepine initiation; and (iii) alternative treatment [sodium valproate (VPA)] prescribing without HLA-B*15:02 screening." | 3.85 | Is universal HLA-B*15:02 screening a cost-effective option in an ethnically diverse population? A case study of Malaysia. ( Apalasamy, YD; Cavallari, LH; Chaiyakunapruk, N; Chong, HY; Dahlui, M; Hao, J; Mohamed, Z; Shabaruddin, FH; Snyder, SR; Tan, LL; Williams, MS; Wu, DBC, 2017) |
| "HLA-B*15:02 screening before carbamazepine (CBZ) prescription in Asian populations is the recommended practice to prevent CBZ-induced Stevens-Johnson syndrome (CBZ-SJS)." | 3.85 | HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis. ( Jaruthamsophon, K; Limprasert, P; Sangiemchoey, A; Sukasem, C; Tipmanee, V, 2017) |
| "The majority of the carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis CBZ-SJS/TEN are associated with HLA-B*15:02 in Asian populations where this allele is common." | 3.85 | HLA-A*31: 01 and HLA-B*15:02 association with Stevens-Johnson syndrome and toxic epidermal necrolysis to carbamazepine in a multiethnic Malaysian population. ( Khor, AH; Kwan, Z; Lim, KS; Ng, CC; Tan, CT; Tan, WC; Wu, DB, 2017) |
| "Carbamazepine (CBZ) is a common cause of life-threatening cutaneous adverse drug reactions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 3.85 | Association of the HLA-B alleles with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in the Javanese and Sundanese population of Indonesia: the important role of the HLA-B75 serotype. ( Cavallari, LH; Kristin, E; Mahasirimongkol, S; Menaldi, SL; Prayuni, K; Sachrowardi, Q; Suyatna, FD; Wichukchinda, N; Yuliwulandari, R, 2017) |
| "To investigate the risk and genetic association of oxcarbazepine-induced cutaneous adverse reactions (OXC-cADRs), including Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), in Asian populations (Chinese and Thai)." | 3.85 | Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians. ( Chang, PY; Chang, WC; Chang, YC; Chen, CB; Chen, DP; Chen, MJ; Chen, YJ; Chiu, TM; Chu, CY; Chung, WH; Ho, HC; Hsiao, YH; Hsih, MS; Hsu, CK; Hsu, CN; Hui, RC; Hung, SI; Jorns, TP; Kao, PH; Kuo, KL; Kuo, TT; Lee, HE; Lin, CY; Lin, JY; Lin, YJ; Lu, CW; Ng, CY; Su, SC; Sukasem, C; Sun, PL; Tassaneeyakul, W; Weng, YC; Wu, CY; Wu, T; Wu, TL; Yang, CH; Yang, CS; Yang, CY, 2017) |
| "HLA-B*15:02 is a known biomarker for carbamazepine (CBZ)-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) in some ethnic populations." | 3.85 | A study of HLA-B*15:02 in 9 different Chinese ethnics: Implications for carbamazepine related SJS/TEN. ( Chen, Q; Ji, X; Jiang, L; Li, L; Liu, Z; Ou, GJ; Su, PC; Wang, J; Yu, H, 2017) |
| "Stevens-Johnson syndrome/toxic epidermal necrolysis after initiation of carbamazepine in a HLA-B*15:02 gene carrier - screening in risk patients is recommended A 32-year-old woman, adopted from Indonesia, developed Stevens-Johnsons syndrome (SJS)/toxic epidermal necrolysis (TEN) after initiating carbamazepine treatment for epilepsy." | 3.85 | [Stevens-Johnson syndrome/toxic epidermal necrolysis after initiation of carbamazepine in a HLA-B*15:02 gene carrier – screening in risk patients is recommended]. ( Anastasopoulou, S; Karlsson, M; Komuda, M; Presman, B; Tomson, T, 2017) |
| " A portion of such reactions is observed to strongly associate with certain human leukocyte antigen (HLA) alleles; one of the strongest associations is the HLA-B*1502 protein with carbamazepine (CBZ)-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) - the odds ratio value can even be higher than one thousand." | 3.83 | Structural modeling of HLA-B*1502/peptide/carbamazepine/T-cell receptor complex architecture: implication for the molecular mechanism of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. ( Huang, J; Wang, Y; Yang, C; Zhang, S; Zhou, P, 2016) |
| " Patient suffered from tumor-related epilepsy, treated pharmacologically with carbamazepine." | 3.83 | Toxic epidermal necrolysis in patient with malignant astrocytoma. ( Bartnik, P; Kacperczyk, J; Kaczmarska-Turek, D; Krasnodębska-Kiljańska, M; Olszewska, M; Orlewski, J, 2016) |
| "The HLA-B*15:02 allele is a risk factor for carbamazepine (CBZ)-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in populations where the allele is prevalent." | 3.83 | The HLA-B*15:02 allele in a Spanish Romani patient with carbamazepine-induced Stevens-Johnson syndrome. ( Aramburu, JA; Bellón, T; Borobia, AM; de Abajo, FJ; González-Herrada, C; Laosa, O; Lerma, V; Moreno-Hidalgo, MA; Ramírez, E, 2016) |
| "Screening for the HLA-B*15:02 allele has been recommended to prevent carbamazepine (CBZ) - induced Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) in individuals with Asian ancestry." | 3.83 | Validation of a novel real-time PCR assay for detection of HLA-B*15:02 allele for prevention of carbamazepine - Induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis in individuals of Asian ancestry. ( Chu, HC; Do, NT; Fernando, SL; Fulton, RB; Le, HT; Li, J; Nguyen, DV; Tran, TT; Vidal, C, 2016) |
| "To construct a simple, low-cost typing method for the surrogate marker of HLA-A*31:01, a risk factor for carbamazepine (CBZ) related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)." | 3.81 | Development of a simple genotyping method for the HLA-A*31:01-tagging SNP in Japanese. ( Aihara, M; Furuya, H; Ikeda, H; Ikezawa, Z; Kaniwa, N; Kinoshita, S; Kitamoto, A; Kitamoto, T; Kurose, K; Maekawa, K; Matsukura, S; Matsunaga, K; Matsuzawa, Y; Mizusawa, S; Muramatsu, M; Nakamura, R; Saito, Y; Sekine, A; Sotozono, C; Sugiyama, E; Takahashi, Y; Uchida, Y; Ueta, M; Ukaji, M; Yagami, A, 2015) |
| "Increasing studies reported genetic susceptibility to drug hypersensitivity reactions, as exemplified by the HLA-A*31:01 and HLA-B*15:02 association with carbamazepine (CBZ)-induced hypersensitivity reactions, such as maculopapular exanthema (MPE), drug rash with eosinophilia and systemic symptoms (DRESS), and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN)." | 3.80 | Genotype-phenotype association between HLA and carbamazepine-induced hypersensitivity reactions: strength and clinical correlations. ( Chang, PY; Chang, WC; Chang, YG; Chen, DP; Chen, MJ; Chung, WH; Ho, HC; Hsiao, YH; Hsih, MS; Hui, RC; Hung, SI; Lin, JY; Wu, T; Wu, TL; Yang, CH, 2014) |
| "Previous studies have demonstrated a strong association between carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) and HLA-B*1502 in Han Chinese." | 3.80 | Association of HLA-B*1502 and *1511 allele with antiepileptic drug-induced Stevens-Johnson syndrome in central China. ( He, XL; Hu, JS; Liu, ZS; Mao, B; Sun, D; Wu, GF; Wu, SH; Xiang, HH; Yu, CH, 2014) |
| "We evaluated the cost and efficiency of routine HLA-B*15 ∶ 02 screening to prevent carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-SJS/TEN) in Hong Kong." | 3.80 | Real-world efficiency of pharmacogenetic screening for carbamazepine-induced severe cutaneous adverse reactions. ( Chen, Z; Kwan, P; Liew, D, 2014) |
| "This study explored the association between the risk of carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and CBZ dose, dose-adjusted concentration, and ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms in patients of Han ethnicity with epilepsy who were living in northeastern China." | 3.80 | Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy. ( He, XJ; He, XL; Jian, LY; Sun, XJ; Tang, M; Wu, Y; Xu, YY; Zhao, LM, 2014) |
| "The occurrence of hypersensitivity reactions including rare but life-threatening Stevens-Johnson syndrome (SJS) and drug-induced hypersensitivity syndrome (HSS) limits the use of the anticonvulsant carbamazepine (CBZ)." | 3.79 | HLA-A 31:01 and HLA-B 15:02 as genetic markers for carbamazepine hypersensitivity in children. ( Amstutz, U; Carleton, BC; Castro-Pastrana, LI; Hayden, MR; Rieder, MJ; Ross, CJ; Shear, NH, 2013) |
| "Carbamazepine (CBZ) is broadly used for the treatment of epilepsy, neuropathic pain and other neurological diseases, owing to its effectiveness and low price." | 3.79 | Cost minimization of HLA-B*1502 screening before prescribing carbamazepine in Thailand. ( Jitpimolmard, J; Jitpimolmard, S; Sawanyawisuth, K; Tiamkao, S, 2013) |
| " We present a case of Stevens-Johnson syndrome in a patient treated with carbamazepine." | 3.79 | A clinical approach to pharmacogenetics. ( de Graaff, LC; van Gelder, T; van Schaik, RH, 2013) |
| "There is strong evidence of an association between the presence of the human leukocyte antigen (HLA)-B*15:02 and two severe adverse drug reactions-Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)-in patients taking carbamazepine (CBZ), a common treatment for patients with epilepsy and neuropathic pain." | 3.79 | Economic evaluation of HLA-B*15:02 screening for carbamazepine-induced severe adverse drug reactions in Thailand. ( Koopitakkajorn, T; Mahasirimongkol, S; Praditsitthikorn, N; Rattanavipapong, W; Teerawattananon, Y, 2013) |
| "This study examined the significant association between carbamazepine (CBZ)-induced Stevens-Johnson Syndrome (SJS)/toxic epidermal necrolysis (TEN) and HLA-B*15:02 in epilepsy patients of Han ethnicity living in northeastern China." | 3.79 | Association between the HLA-B*15:02 allele and carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Han individuals of northeastern China. ( He, XJ; He, XL; Jian, LY; Miao, LY; Sun, XJ; Wu, Y; Xu, YY; Zhao, LM, 2013) |
| "It is known that rare but severe cutaneous adverse drug reactions (cADRs), such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and drug-induced hypersensitivity syndrome (DIHS), are induced by carbamazepine (CBZ)." | 3.79 | Development of a simple method for detection of the HLA-A*31:01 allele. ( Ariyoshi, N; Ishii, I; Kitada, M; Kubota, F; Matsumoto, J; Uchiyama, K, 2013) |
| "Carbamazepine (CBZ) is the most frequent culprit drug for severe cutaneous adverse drug reactions (ADR), such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and drug-induced hypersensitivity syndrome (DIHS)." | 3.78 | HLA-A31 strongly associates with carbamazepine-induced adverse drug reactions but not with carbamazepine-induced lymphocyte proliferation in a Japanese population. ( Fujita, Y; Kakamu, T; Kaneko, S; Morita, E; Niihara, H, 2012) |
| "We adopted the HLA-B∗1502 genetic predisposition to carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) as a model to study the pathologic role of HLA in delayed-type drug hypersensitivity." | 3.78 | Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome. ( Chen, YT; Chung, WH; Huang, HW; Hung, SI; Wei, CY, 2012) |
| "Previous studies have demonstrated a strong association between carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-induced SJS/TEN) and HLA-B*1502 in Chinese, and HLA-A*3101 but not HLA-B*1502 in Caucasians and Japanese." | 3.78 | Association between HLA and Stevens-Johnson syndrome induced by carbamazepine in Southern Han Chinese: genetic markers besides B*1502? ( Gao, MM; Liao, WP; Liu, XR; Min, FL; Qin, B; Shi, YW; Wang, Q; Zhou, JQ; Zou, X, 2012) |
| "Asians who carry the HLA-B*1502 allele have an elevated risk of developing Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) when treated with the antiepileptic drugs (AEDs) carbamazepine (CBZ) and phenytoin (PHT)." | 3.78 | Cost-effectiveness of HLA-B*1502 genotyping in adult patients with newly diagnosed epilepsy in Singapore. ( Dong, D; Finkelstein, EA; Sung, C, 2012) |
| "Carbamazepine (CBZ), a frequently used anticonvulsant drug, is one of the most common causes of life-threatening cutaneous adverse drug reactions such as toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS)." | 3.77 | Association of HLA-B*1502 allele with carbamazepine-induced toxic epidermal necrolysis and Stevens-Johnson syndrome in the multi-ethnic Malaysian population. ( Chang, CC; Hussein, SH; Murad, S; Too, CL, 2011) |
| "Previous studies have found a strong association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome in Asian areas including Taiwan, Hongkong and Thailand." | 3.77 | Association between HLA-B*1502 allele and carbamazepine-induced severe cutaneous adverse reactions in Han people of southern China mainland. ( Cai, XD; Chen, SD; Chen, ZY; Dai, QL; Fang, ZY; Hong, H; Wang, HX; Wang, Q; Yang, LB; Zhou, JQ; Zhou, LM, 2011) |
| "Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main cause of the Stevens-Johnson syndrome (SJS) and its related disease, toxic epidermal necrolysis (TEN), in Southeast Asian countries." | 3.77 | Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan. ( Chang, CF; Chen, CH; Chen, L; Chen, P; Chen, YJ; Chen, YT; Chu, CC; Chuang, HP; Chung, WH; Hsieh, PF; Hsu, YC; Huang, LC; Hung, SI; Lan, SH; Liao, HT; Lin, JJ; Lin, SY; Lin, YH; Lu, CH; Lu, CS; Lu, CT; Ong, CT; Ro, LS; Shen, CY; Su, YH; Sung, SF; Tai, CT; Tsai, JJ; Tsai, PJ; Wu, JY; Wu, SL; Yang, CC; Yu, HY, 2011) |
| "Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopapular exanthema to severe blistering reactions." | 3.77 | HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. ( Alfirevic, A; Alhusaini, S; Bourgeois, S; Carrington, M; Cavalleri, GL; Chaila, E; Chinthapalli, K; de Bakker, PI; Delanty, N; Deloukas, P; Depondt, C; Farrell, JJ; Goldstein, DB; Heinzen, EL; Jia, X; Johnson, MR; Kasperavičiūtė, D; Marson, T; McCormack, M; Molokhia, M; O'Connor, GD; Pandolfo, M; Park, BK; Pichler, W; Pirmohamed, M; Radtke, RA; Shianna, KV; Sills, GJ; Sisodiya, SM; Walley, N, 2011) |
| "Twenty-four patients who had developed carbamazepine-induced SCAR (7 Stevens-Johnson syndrome (SJS), 17 drug hypersensitivity syndrome (HSS)), 50 carbamazepine-tolerant controls from the Korean Pharmacogenetic Adverse Drug Reaction Research Network and data of 485 Korean general population from a previously published study were recruited." | 3.77 | Carbamazepine-induced severe cutaneous adverse reactions and HLA genotypes in Koreans. ( Chang, YS; Cho, SH; Jee, YK; Kang, HR; Kim, SH; Lee, KW; Lee, SM; Min, KU; Park, HW; Park, SH; Song, WJ, 2011) |
| "We describe the association of the HLA-B*1502 allele in 27 epilepsy patients (19 Malays, 8 Chinese) treated with carbamazepine (CBZ) at the UKM Medical Center (UKMMC), 6 with CBZ-Steven Johnson Syndrome (CBZ-SJS), 11 with CBZ-induced rash, 2 with suspected phenytoin-induced rash and 8 negative controls." | 3.77 | Frequency of the HLA-B*1502 allele contributing to carbamazepine-induced hypersensitivity reactions in a cohort of Malaysian epilepsy patients. ( Jamal, R; Rani, ZZ; Ratnaningrum, S; Raymond, AA; Then, SM, 2011) |
| "Carbamazepine (CBZ) is frequently used for treating epilepsy, but this drug causes cutaneous adverse drug reactions (cADRs) that may range from mild to severe." | 3.76 | HLA class I markers in Japanese patients with carbamazepine-induced cutaneous adverse reactions. ( Aihara, M; Fujiwara, T; Ikeda, H; Kaniwa, N; Kashiwagi, M; Muramatsu, M; Saito, Y; Takahashi, Y; Yamazaki, E, 2010) |
| "Carbamazepine (CBZ) has been reported as the most common culprit drug for Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in several Asian countries including Thailand." | 3.76 | Association between HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in a Thai population. ( Aungaree, T; Auvichayapat, N; Chen, P; Chen, WH; Choonhakarn, C; Jantararoungtong, T; Khunarkornsiri, U; Konyoung, P; Kulkantrakorn, K; Lin, SY; Pavakul, K; Phonhiamhan, S; Piyatrakul, N; Pongpakdee, S; Tassaneeyakul, W; Tiamkao, S; Yodnopaglaw, P, 2010) |
| " Although a lymphocyte stimulation test was positive only for acetaminophen, he took other agents including carbamazepine for his depression." | 3.76 | Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7. ( Honma, M; Iinuma, S; Iizuka, H; Ishida-Yamamoto, A; Komatsu, S; Shibuya, T; Takahashi, I; Tobisawa, S, 2010) |
| "Although carbamazepine (CBZ) is the most common cause of Stevens-Johnson syndrome (SJS), a new anticonvulsant, oxcarbazepine, which is structurally related to carbamazepine, has been shown to induce SJS, although extremely rarely." | 3.75 | Oxcarbazepine-induced Stevens-Johnson syndrome: a case report. ( Lai, PC; Lin, LC; Yang, RC; Yang, SF, 2009) |
| "Previous studies found a strong association between HLA-B*1502 and carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) in Han Chinese, but not in Caucasian populations." | 3.74 | Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population. ( Desudchit, T; Hirankarn, N; Kangwanshiratada, O; Korkij, W; Limotai, C; Locharernkul, C; Loplumlert, J; Shotelersuk, V; Suphapeetiporn, K; Tongkobpetch, S, 2008) |
| "This study investigated the association between 2 mood stabilizers (carbamazepine and valproate) and other medications (including other anticonvulsants) and the risks of erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) among patients with bipolar disorder." | 3.74 | The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study. ( Chang, CJ; Chao, PF; Gau, CS; Gau, SS; Lin, YJ, 2008) |
| "A previous study conducted in Taiwan found a 100% association between HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome (SJS) in Han Chinese subjects, with an extremely high odds ratio compared with carbamazepine-tolerant subjects (odds ratio = 2,504)." | 3.74 | Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. ( Baum, L; Cheng, AS; Kwan, P; Lau, KM; Man, CB; Ng, MH; Yu, E, 2007) |
| "Across a range of assumptions used, the risk of hospitalization for Stevens-Johnson syndrome or toxic epidermal necrolysis in new users is low for carbamazepine, lamotrigine, phenytoin, phenobarbital, and valproic acid." | 3.73 | Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics. ( Messenheimer, J; Mockenhaupt, M; Schlingmann, J; Tennis, P, 2005) |
| "The anticonvulsant carbamazepine (CBZ) frequently causes cutaneous adverse drug reactions (cADRs), including maculopapular eruption (MPE), hypersensitivity syndrome (HSS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 3.73 | Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. ( Chang, YT; Chen, GS; Chen, WC; Chen, WH; Chen, YT; Chung, WH; Fang, WH; Hsiao, PF; Hu, SL; Huang, YL; Hung, SI; Jee, SH; Lee, WR; Lin, JJ; Lou, YH; Shih, HY; Wei, CY; Wong, TW; Wu, MT, 2006) |
| "Two patients with psychotic disorders who developed Stevens-Johnson Syndrome while on treatment with carbamazepine is reported due to its rarity." | 3.70 | Stevens-Johnson syndrome due to carbamazepine. ( Chaudhury, S; John, TR; Ramadasan, P; Vaishampayne, S, 2000) |
| "Toxic epidermal necrolysis (Lyell syndrome) developed in a 43-year woman treated with carbamazepine, perazine, and sulpiride for recurrent manic bipolar disorder." | 3.68 | [Electroconvulsive therapy in treatment of acute life threatening catatonia in toxic epidermal necrolysis (Lyell syndrome)]. ( Beckmann, H; Kornhuber, J; Weller, M, 1992) |
| "Three cases of Stevens-Johnson Syndrome developing after the addition of Carbamazepine to existing neuroleptic medication are described." | 3.68 | Stevens-Johnson syndrome in neuroleptic-carbamazepine combination. ( Wong, KE, 1990) |
| "A bipolar patient is described in whom erythema multiforme major, or Stevens-Johnson syndrome, developed after treatment with carbamazepine." | 3.67 | Erythema multiforme major in a patient treated with carbamazepine. ( Fawcett, RG, 1987) |
| "Stevens-Johnson syndrome (SJS) /toxic epidermal necrolysis (TEN) are life-threatening severe cutaneous adverse drug reactions characterized by widespread epidermal necrosis." | 2.90 | Comprehensive assessment of T cell receptor β repertoire in Stevens-Johnson syndrome/toxic epidermal necrolysis patients using high-throughput sequencing. ( Chen, S; Jiang, M; Luo, X; Qin, S; Tang, C; Wang, L; Xing, Q; Xiong, H; Yang, F; Zhu, H; Zhu, Q, 2019) |
| "Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute life-threatening mucocutaneous drug reactions." | 2.72 | Carbamazepine-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review. ( Al Abri, AM; Al Rajaibi, R; Al Rumhi, T, 2021) |
| "Lamotrigine is an antiepileptic drug of the phenyltriazine class that is indicated for the prevention of focal and generalized seizures in epileptic patients as well as monotherapy or adjunctive maintenance treatment for Bipolar disorder." | 2.72 | Lamotrigine and Stevens-Johnson Syndrome Prevention. ( Crane, E; Edinoff, AN; Fitz-Gerald, MJ; Gennuso, SA; Kaye, AD; Kaye, AM; Kaye, JS; Kaye, RJ; Lewis, K; Nguyen, LH; Pierre, SS; Urits, I; Varrassi, G; Viswanath, O, 2021) |
| "Because methods to predict type 1 diabetes by using genetic and immunologic biomarkers have been developed to a high level of accuracy (predicting 100% of subjects likely to progress), new research strategies based on these methods might also improve the ability to predict drug hypersensitivity." | 2.52 | New approaches for predicting T cell-mediated drug reactions: A role for inducible and potentially preventable autoimmunity. ( Michels, AW; Ostrov, DA, 2015) |
| "Among them, drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome (DIHS), Stevens-Johnson syndrome/ toxic epidermal necrolysis (SJS/TEN), are some of the most life-threatening severe cutaneous adverse reactions (SCARs)." | 2.50 | HLA associations and clinical implications in T-cell mediated drug hypersensitivity reactions: an updated review. ( Chen, CH; Chen, WL; Cheng, CY; Chung, WH; Deng, ST; Su, SC, 2014) |
| "However, the genetic susceptibility and the exact pathogenesis were not clear until the recent studies." | 2.46 | Genetic markers and danger signals in stevens-johnson syndrome and toxic epidermal necrolysis. ( Chung, WH; Hung, SI, 2010) |
| "Median time-to-onset for any type of SCAR was 13 days, regardless of age." | 1.91 | Carbamazepine-Induced Severe Cutaneous Adverse Drug Reactions: A 21-Year Comparison Between Children and Adults in Malaysia. ( Hariraj, V; Lee, SC; Ramli, A; Wo, WK, 2023) |
| "Studies assessing SCARs using real-world evidence are very limited." | 1.72 | Analysis of severe cutaneous adverse reactions (SCARs) in Taiwan drug-injury relief system: 18-year results. ( Chen, WW; Chien, MY; Chiou, MH; Chu, CY; Huang, PW, 2022) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse drug reactions." | 1.72 | Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti-seizure medications. ( Anderson, A; Baum, L; Chen, Z; Cherny, S; Ding, JH; Kwan, P; Liao, WP; Lim, KS; Mullan, KA; Ng, CC; Petrovski, S; Sham, PC; Shi, YW, 2022) |
| "Carbamazepine (CBZ) is an FDA-approved anticonvulsant that is widely used to treat epilepsy, bipolar disorder, trigeminal neuralgia and chronic pain." | 1.72 | Development of label-free electrochemical impedance spectroscopy for the detection of HLA-B*15:02 and HLA-B*15:21 for the prevention of carbamazepine-induced Stevens-Johnson syndrome. ( Attapong, J; Chomean, S; Kaset, C; Nakkam, N; Tassaneeyakul, W, 2022) |
| "Levetiracetam is an increasingly used new non-aromatic antiepileptic drug and reported to have a better safety profile in daily practice." | 1.62 | Anaphylaxis to levetiracetam in an adolescent: a very rare occurence. ( Arhan, E; Bakırtaş, A; Değermenci, Ş; Ertoy-Karagöl, Hİ; Güleryüz, OD; Kahraman, Ş; Menderes, D; Oktay, MA, 2021) |
| "Epilepsy is very difficult to treat and often involves the combination of two or more AEDs." | 1.56 | Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database. ( Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H, 2020) |
| "Despite morbidities and fatalities, nationwide epidemiologic data for severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS), are not widely available." | 1.51 | Analysis of Individual Case Safety Reports of Severe Cutaneous Adverse Reactions in Korea. ( Kang, DY; Kang, HR; Kang, MG; Lee, JY; Park, HK; Sohn, KH; Yang, MS, 2019) |
| "Allopurinol treatment, based on screening by HLA-B*58:01 genotyping, could be more cost-effective than that not based on screening." | 1.43 | HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs. ( Kim, DH; Kim, J; Kim, YJ; Lee, JH; Park, HJ; Park, JW; Park, KH, 2016) |
| "Early Toxic Epidermal Necrolysis (TEN) syndrome was diagnosed by the Burns and Dermatology teams and the culprit drug was discontinued." | 1.43 | Early toxic epidermal necrolysis syndrome post-intra-cranial tumor resection. ( Petrilli, RM; Ramachandren, TK, 2016) |
| " In this research, we have explored the feasibility of retrospectively mapping population-level adverse events from the FDA Adverse Event Reporting System (FAERS) to chemical and biological databases to identify drug safety signals and the underlying molecular mechanisms." | 1.43 | Improving drug safety with a systems pharmacology approach. ( Bojunga, N; Lesko, LJ; Schotland, P; Trame, MN; Zien, A, 2016) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious cutaneous adverse reactions." | 1.42 | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. ( Bai, JP; Hur, J; Zhao, C, 2015) |
| "International experts in the field of drug allergy with backgrounds in allergy, immunology, infectious diseases, dermatology, clinical pharmacology, and pharmacogenomics discussed the current state of drug allergy research." | 1.42 | Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy. ( Banerji, A; Castells, M; Finkelman, FD; Gleich, GJ; Guttman-Yassky, E; Mallal, SA; Naisbitt, DJ; Ostrov, DA; Phillips, EJ; Pichler, WJ; Platts-Mills, TA; Plaut, M; Roujeau, JC; Schwaninger, JM; Schwartz, LB; Trepanier, LA; Wheatley, LM, 2015) |
| "Carbamazepine (CBZ) has been commonly implicated in SJS." | 1.39 | Combination of Steven-Johnson syndrome and neuroleptic malignant syndrome following carbamazepine therapy: a rare occurrence. ( Dubey, P; Gandhi, P; Panagariya, A; Sannegowda, RB; Sharma, B, 2013) |
| " Genetic analysis of DHS patients has revealed a striking association between carbamazepine (CBZ)-induced severe bullous reactions, such as Steven-Johnson Syndrome, and toxic epidermal necrolysis in individuals from Southeast Asia who carry a specific HLA allele (HLA-B*1502)." | 1.37 | Severe bullous hypersensitivity reactions after exposure to carbamazepine in a Han-Chinese child with a positive HLA-B*1502 and negative in vitro toxicity assays: evidence for different pathophysiological mechanisms. ( Bend, JR; Elzagallaai, AA; Finkelstein, Y; Garcia-Bournissen, F; Koren, G; Rieder, MJ, 2011) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening severe cutaneous adverse reactions." | 1.36 | HLA-B*1511 is a risk factor for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients. ( Abe, M; Aihara, M; Furuya, H; Hasegawa, R; Ikeda, H; Ikezawa, Z; Kaniwa, N; Kashiwagi, M; Kinoshita, S; Kurose, K; Matsunaga, K; Muramatsu, M; Saito, Y; Song, Y; Sotozono, C; Takahashi, Y; Tohkin, M; Ueta, M, 2010) |
| "Acute generalised exanthematous pustulosis and Stevens-Johnson syndrome (toxic epidermal necrolysis spectrum of severe cutaneous drug reactions) are believed to have distinct underlying pathophysiologies." | 1.35 | Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine. ( Goh, SG; Goh, TK; Pang, SM; Thirumoorthy, T, 2008) |
| " His skin signs appeared 1 day after the last dosage increment." | 1.35 | Toxic epidermal necrolysis in a child after carbamazepine dosage increment. ( Akman, M; Bicer, S; Hatipoglu, S; Sevketoglu, E, 2009) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can involve MHC-restricted presentation of a drug or its metabolites for T-cell activation." | 1.34 | HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome. ( Chen, ST; Chen, YT; Fang, WH; Hung, SI; Juo, CG; Lin, YP; Lu, IH; Yang, CW, 2007) |
| "The HLA-DRB and -DRQ genetic predisposition to SJS seemed to be distinct from that of TEN, but further work is needed for both conditions to identify the causal variants." | 1.34 | Investigation into the multidimensional genetic basis of drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis. ( Arbuckle, JB; Bowman, CE; Brunner, M; Burns, DK; Delrieu, O; Dix, LP; Pirmohamed, M; Stern, RS; Twomey, JA, 2007) |
| "Carbamazepine was then stopped." | 1.32 | Spectrum of anticonvulsant hypersensitivity syndrome: controversy of treatment. ( Chung, BH; Fung, CW; Lee, WC; Leung, JL; Wong, V, 2004) |
| "Toxic epidermal necrolysis is a severe reaction with skin involvement induced by different drugs and other agents." | 1.31 | Anticonvulsant-induced toxic epidermal necrolysis: monitoring the immunologic response. ( Besso, G; Blanca, M; del Moral, RG; Juárez, C; Leyva, L; O'Valle, F; Posadas, S; Santamaría, LF; Torres, MJ, 2000) |
| "A patient developed toxic epidermal necrolysis while on carbamazepine, 80% of her skin surface being involved." | 1.30 | Toxic epidermal necrolysis treated with cyclosporin and granulocyte colony stimulating factor. ( Havill, J; Jarrett, P; Pullon, H; Rademaker, M, 1997) |
| "Carbamazepine is an anticonvulsant associated with a high risk for severe cutaneous reactions." | 1.30 | Covalent binding of carbamazepine reactive metabolites to P450 isoforms present in the skin. ( Bagot, M; Beaune, P; Charue, D; Garcia-Martin, N; Lecoeur, S; Tan, C; Wechsler, J; Wolkenstein, P, 1998) |
| "Heroin and alcohol abuse alters host immunity which subsequently may increase susceptibility to allergic reactions." | 1.30 | [Stevens-Johnson syndrome with transition to toxic epidermal necrolysis after carbamazepine administration, heroin and alcohol abuse]. ( Haustein, UF; Petter, G, 1999) |
| "Erythema multiforme and toxic epidermal necrolysis can occur as serious and even life-threatening adverse drug reactions." | 1.29 | Investigation of mechanisms in toxic epidermal necrolysis induced by carbamazepine. ( Friedmann, PS; Park, BK; Pirmohamed, M; Strickland, I, 1994) |
| "We report on the first fatal course of toxic epidermal necrolysis (Lyell's disease) occurring under treatment with lamotrigine, following the development of a skin rash caused by carbamazepine." | 1.29 | Fatal course of toxic epidermal necrolysis under treatment with lamotrigine. ( Berrouschot, J; Schneider, D; Sterker, M, 1995) |
| "Toxic epidermal necrolysis (TEN) or Lyell's syndrome is a rare fulminating skin disease notorious for its rapidly progressive course and high mortality rate." | 1.28 | Plasma exchange (PE) treatment in drug-induced toxic epidermal necrolysis (TEN). ( Alexopoulos, E; Chrisomalis, F; Karpouzas, J; Koukoudis, P; Papadimitriou, M; Papadopoulou, D; Sakellariou, G; Skenteris, N; Tsakaris, D, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (4.44) | 18.7374 |
| 1990's | 20 (8.89) | 18.2507 |
| 2000's | 40 (17.78) | 29.6817 |
| 2010's | 122 (54.22) | 24.3611 |
| 2020's | 33 (14.67) | 2.80 |
| Authors | Studies |
|---|---|
| Al Rajaibi, R | 1 |
| Al Rumhi, T | 1 |
| Al Abri, AM | 1 |
| Wong, CSM | 1 |
| Yap, DYH | 1 |
| Ip, P | 1 |
| Wong, WHS | 1 |
| Chua, GT | 1 |
| Yeung, CK | 1 |
| Chan, HHL | 1 |
| Kwok, JSY | 1 |
| Huang, PW | 1 |
| Chiou, MH | 1 |
| Chien, MY | 1 |
| Chen, WW | 2 |
| Chu, CY | 4 |
| Mullan, KA | 1 |
| Anderson, A | 1 |
| Shi, YW | 3 |
| Ding, JH | 1 |
| Ng, CC | 4 |
| Chen, Z | 2 |
| Baum, L | 2 |
| Cherny, S | 1 |
| Petrovski, S | 1 |
| Sham, PC | 1 |
| Lim, KS | 4 |
| Liao, WP | 3 |
| Kwan, P | 5 |
| Mortazavi, H | 1 |
| Rostami, A | 1 |
| Firooz, A | 1 |
| Esmaili, N | 1 |
| Ghiasi, M | 1 |
| Lajevardi, V | 1 |
| Amirzargar, AA | 1 |
| Sheykhi, I | 1 |
| Khamesipour, A | 1 |
| Akhdar, M | 1 |
| Zheng, Y | 1 |
| Zhou, W | 1 |
| Guo, X | 1 |
| Chi, L | 1 |
| Chen, C | 1 |
| Guo, Z | 1 |
| Liang, J | 1 |
| Wei, L | 1 |
| Chen, X | 1 |
| Ye, X | 1 |
| He, J | 1 |
| Min, F | 1 |
| Fan, C | 1 |
| Zeng, Y | 1 |
| He, N | 1 |
| Zeng, T | 1 |
| Qin, B | 2 |
| Shi, Y | 1 |
| Chomean, S | 1 |
| Nakkam, N | 1 |
| Tassaneeyakul, W | 6 |
| Attapong, J | 1 |
| Kaset, C | 1 |
| Dastgheib, L | 1 |
| Rostami, F | 1 |
| Gharesi-Fard, B | 1 |
| Asadi-Pooya, AA | 1 |
| Namjoo, S | 1 |
| Tahmasebi, F | 1 |
| Hadibarhaghtalab, M | 1 |
| Haukamp, FJ | 1 |
| Hartmann, ZM | 1 |
| Pich, A | 1 |
| Kuhn, J | 1 |
| Blasczyk, R | 1 |
| Stieglitz, F | 1 |
| Bade-Döding, C | 1 |
| Jaruthamsophon, K | 2 |
| Thomson, PJ | 1 |
| Hammond, S | 1 |
| Zhang, E | 1 |
| Alfirevic, A | 3 |
| Sukasem, C | 3 |
| Naisbitt, DJ | 2 |
| Pirmohamed, M | 9 |
| Hariraj, V | 1 |
| Wo, WK | 1 |
| Lee, SC | 1 |
| Ramli, A | 1 |
| Chong, HY | 2 |
| Fong, SL | 1 |
| Shabaruddin, FH | 2 |
| Dahlui, M | 2 |
| Mei Lai, PS | 1 |
| Chaiyakunapruk, N | 3 |
| Xu, YY | 3 |
| Sun, ZL | 1 |
| Zhang, XL | 1 |
| Liu, ZL | 1 |
| Liu, W | 1 |
| Guan, X | 1 |
| Garg, VK | 2 |
| Buttar, HS | 1 |
| Bhat, SA | 1 |
| Ainur, N | 1 |
| Priya, T | 1 |
| Kashyap, D | 1 |
| Tuli, HS | 1 |
| Bui, VL | 1 |
| Alvarez-Arango, S | 1 |
| Stevenson, JM | 1 |
| Pan, RY | 2 |
| Chu, MT | 1 |
| Wang, CW | 2 |
| Lee, YS | 1 |
| Lemonnier, F | 1 |
| Michels, AW | 2 |
| Schutte, R | 1 |
| Ostrov, DA | 4 |
| Chen, CB | 3 |
| Phillips, EJ | 5 |
| Mallal, SA | 3 |
| Mockenhaupt, M | 4 |
| Bellón, T | 3 |
| White, KD | 2 |
| Roujeau, JC | 6 |
| Chung, WH | 17 |
| Hung, SI | 16 |
| Saito, Y | 6 |
| Nakamura, R | 2 |
| Capule, F | 1 |
| Tragulpiankit, P | 1 |
| Mahasirimongkol, S | 5 |
| Jittikoon, J | 1 |
| Wichukchinda, N | 2 |
| Theresa Alentajan-Aleta, L | 1 |
| James Barit, JV | 1 |
| Casanova-Gutierrez, J | 1 |
| Cabral-Lim, L | 1 |
| Baltazar Reyes, JP | 1 |
| Roa, F | 1 |
| Salonga, R | 1 |
| San Gabriel, KF | 1 |
| Lynn Silao, C | 1 |
| Oussalah, A | 1 |
| Yip, V | 1 |
| Mayorga, C | 1 |
| Blanca, M | 2 |
| Barbaud, A | 2 |
| Nakonechna, A | 1 |
| Cernadas, J | 1 |
| Gotua, M | 1 |
| Brockow, K | 1 |
| Caubet, JC | 1 |
| Bircher, A | 1 |
| Atanaskovic-Markovic, M | 2 |
| Demoly, P | 1 |
| Kase-Tanno, L | 1 |
| Terreehorst, I | 1 |
| Laguna, JJ | 1 |
| Romano, A | 2 |
| Guéant, JL | 1 |
| Toussaint, C | 1 |
| Sanchez-Pena, P | 1 |
| Titier, K | 1 |
| Castaing, N | 1 |
| Molimard, M | 1 |
| Milpied, B | 3 |
| Sawal, N | 1 |
| Kanga, U | 1 |
| Shukla, G | 1 |
| Goyal, V | 1 |
| Srivastava, AK | 1 |
| Noguchi, Y | 1 |
| Takaoka, M | 1 |
| Hayashi, T | 1 |
| Tachi, T | 1 |
| Teramachi, H | 1 |
| Liu, H | 1 |
| Lan, S | 1 |
| Liu, D | 1 |
| Xu, M | 1 |
| Yi, Y | 1 |
| Li, B | 1 |
| Liu, X | 1 |
| Kang, DY | 2 |
| Yun, J | 1 |
| Lee, SY | 1 |
| Koh, YI | 1 |
| Sim, DW | 1 |
| Kim, S | 1 |
| Nam, YH | 1 |
| Park, JW | 2 |
| Kim, SH | 5 |
| Ye, YM | 1 |
| Park, HK | 2 |
| Kim, MH | 1 |
| Jee, YK | 2 |
| Jung, JW | 1 |
| Yang, MS | 2 |
| Lee, JK | 1 |
| Kim, CW | 1 |
| Hur, GY | 1 |
| Kim, MY | 1 |
| Park, SJ | 1 |
| Kwon, YE | 1 |
| Choi, JH | 1 |
| Kim, JH | 1 |
| La, HO | 1 |
| Kang, MG | 2 |
| Park, CS | 1 |
| Lee, SM | 2 |
| Jeong, YY | 1 |
| Kim, HK | 1 |
| Jin, HJ | 1 |
| Jeong, JW | 1 |
| Lee, J | 1 |
| Lee, YW | 1 |
| Lee, SE | 1 |
| Kim, MS | 1 |
| Kang, HR | 3 |
| Chung, SJ | 1 |
| Ahn, KM | 1 |
| Oh, JH | 1 |
| Shim, JS | 1 |
| Park, HW | 2 |
| Sargent, B | 1 |
| Juhasz, MLW | 1 |
| Joe, VC | 1 |
| Lee, BA | 1 |
| Rojek, NW | 1 |
| Fukasawa, T | 1 |
| Takahashi, H | 1 |
| Takahashi, K | 1 |
| Tanemura, N | 1 |
| Amagai, M | 1 |
| Urushihara, H | 1 |
| Yuliwulandari, R | 2 |
| Shin, JG | 1 |
| Kristin, E | 2 |
| Suyatna, FD | 2 |
| Prahasto, ID | 1 |
| Prayuni, K | 2 |
| Cavallari, LH | 3 |
| Mitropoulou, C | 1 |
| Patrinos, GP | 2 |
| Hao, J | 2 |
| Williams, MS | 2 |
| Snyder, SR | 2 |
| Monnet, P | 1 |
| Rodriguez, C | 1 |
| Gaudin, O | 1 |
| Cirotteau, P | 1 |
| Papouin, B | 1 |
| Dereure, O | 1 |
| Tetart, F | 1 |
| Lalevee, S | 1 |
| Colin, A | 1 |
| Lebrun-Vignes, B | 1 |
| Abe, E | 1 |
| Alvarez, JC | 1 |
| Demontant, V | 1 |
| Gricourt, G | 1 |
| de Prost, N | 1 |
| Barau, C | 1 |
| Chosidow, O | 1 |
| Wolkenstein, P | 2 |
| Hue, S | 1 |
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| Ingen-Housz-Oro, S | 1 |
| Jiang, B | 1 |
| Oh, CC | 1 |
| Tan, KW | 1 |
| Lee, HY | 2 |
| Xu, C | 1 |
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| Tensini, TS | 1 |
| Von Glehn, CQC | 1 |
| Bettinotti, MP | 1 |
| Iglehart, B | 1 |
| de Paola, L | 1 |
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| Braatz, VL | 1 |
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| Fitz-Gerald, MJ | 1 |
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| Kaye, AD | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| HLA Screening in Reducing the Risk of Antiepileptic Drug-induced Cutaneous Adverse Reactions: a Multicenter Clinical Study[NCT03184597] | 4,000 participants (Anticipated) | Interventional | 2017-08-01 | Recruiting | |||
| A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency[NCT01379469] | Phase 2 | 20 participants (Actual) | Interventional | 2012-01-31 | Terminated | ||
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
33 reviews available for carbamazepine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Carbamazepine-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review.
Topics: Adult; Carbamazepine; Cyclosporine; Female; Humans; Oman; Stevens-Johnson Syndrome | 2021 |
[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy].
Topics: Acetaminophen; Adrenal Cortex Hormones; Allopurinol; Antigens, Differentiation, T-Lymphocyte; Carbam | 2019 |
Genetic variants associated with T cell-mediated cutaneous adverse drug reactions: A PRISMA-compliant systematic review-An EAACI position paper.
Topics: Carbamazepine; Drug Hypersensitivity; Drug Hypersensitivity Syndrome; HLA-B Antigens; Humans; Pharma | 2020 |
Lamotrigine and Stevens-Johnson Syndrome Prevention.
Topics: Anticonvulsants; Carbamazepine; HLA-B Antigens; Humans; Lamotrigine; Stevens-Johnson Syndrome; Unite | 2021 |
Association between the HLA-B alleles and carbamazepine-induced SJS/TEN: A meta-analysis.
Topics: Asian People; Carbamazepine; Genetic Predisposition to Disease; HLA-B Antigens; Humans; Stevens-John | 2017 |
Controversies in drug allergy: Testing for delayed reactions.
Topics: Animals; Asian People; Carbamazepine; Dideoxynucleosides; HLA-B Antigens; HLA-B15 Antigen; Humans; S | 2019 |
Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions.
Topics: Adult; Anaplastic Lymphoma Kinase; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Hyper | 2019 |
Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury.
Topics: Alleles; Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Azetidines; Benzylamines; Carba | 2013 |
Relationship between the HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis.
Topics: Anticonvulsants; Asian People; Carbamazepine; HLA-B Antigens; Humans; Mass Screening; Outcome Assess | 2013 |
[The associations between idiosyncratic adverse drug reactions and HLA alleles and their underlying mechanism].
Topics: Alleles; Allopurinol; Anti-HIV Agents; Anticonvulsants; Carbamazepine; Dideoxynucleosides; Drug Hype | 2013 |
Genotyping for severe drug hypersensitivity.
Topics: Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Carbamazepine; Dideoxynucleosides; Drug | 2014 |
Pharmacogenetic markers of severe cutaneous adverse drug reactions.
Topics: Allopurinol; Anti-HIV Agents; Anticonvulsants; Biomarkers; Carbamazepine; Dideoxynucleosides; Drug E | 2014 |
HLA associations and clinical implications in T-cell mediated drug hypersensitivity reactions: an updated review.
Topics: Alleles; Allopurinol; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity Syndrome; Gene Expres | 2014 |
HLA-B*15:02 association with carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in an Indian population: a pooled-data analysis and meta-analysis.
Topics: Adolescent; Adult; Aged; Asian People; Carbamazepine; Epidermis; Female; Gene Frequency; Genetic Pre | 2014 |
Clinical application of pharmacogenomics: the example of HLA-based drug-induced toxicity.
Topics: Acute Generalized Exanthematous Pustulosis; Alleles; Allopurinol; Anticonvulsants; Antimetabolites; | 2014 |
New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity.
Topics: Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Gene Expression Regulation; Genetic Hetero | 2015 |
Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.
Topics: Allopurinol; B-Lymphocytes; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Gene Expressio | 2015 |
New approaches for predicting T cell-mediated drug reactions: A role for inducible and potentially preventable autoimmunity.
Topics: Autoimmunity; Carbamazepine; Diabetes Mellitus, Type 1; Dideoxynucleosides; Drug Hypersensitivity; G | 2015 |
A review of toxic epidermal necrolysis management in Japan.
Topics: Allopurinol; Carbamazepine; Female; HLA-B Antigens; HLA-B15 Antigen; Humans; Japan; Male; Stevens-Jo | 2017 |
Severe Cutaneous Adverse Reactions: The Pharmacogenomics from Research to Clinical Implementation.
Topics: Allopurinol; Anti-HIV Agents; Anticonvulsants; Biomarkers; Carbamazepine; Dideoxynucleosides; Geneti | 2016 |
Extended septic thrombophlebitis in a patient with duplicated inferior vena cava: case report and review of literature.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticoagulants; Carbamazepine; Enterobacter cloacae | 2009 |
Genetic basis for idiosyncratic reactions to antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Epile | 2009 |
Genetic predisposition of life-threatening antiepileptic-induced skin reactions.
Topics: Anticonvulsants; Carbamazepine; Drug Labeling; Gene Frequency; Genetic Predisposition to Disease; HL | 2010 |
Genetic markers and danger signals in stevens-johnson syndrome and toxic epidermal necrolysis.
Topics: Allopurinol; Apoptosis; Biomarkers; Carbamazepine; Cytotoxicity, Immunologic; Genetic Predisposition | 2010 |
[Exploratory study on biomarkers associated with severe cutaneous adverse reactions].
Topics: Allopurinol; Carbamazepine; HLA-B Antigens; Humans; Pharmacogenetics; Racial Groups; Stevens-Johnson | 2011 |
Pharmacogenetics of cutaneous adverse drug reactions.
Topics: Allopurinol; Anti-Retroviral Agents; Anticonvulsants; Asian People; Carbamazepine; Drug Eruptions; E | 2011 |
Pharmacogenetic screening of carbamazepine-induced severe cutaneous allergic reactions.
Topics: Asian People; Carbamazepine; Dermatitis, Contact; Genetic Testing; HLA-B15 Antigen; Humans; Incidenc | 2011 |
HLA alleles and drug hypersensitivity reactions.
Topics: Alleles; Allopurinol; Anti-HIV Agents; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Gen | 2012 |
T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Genetic Predisposition to Disease; HLA-B Anti | 2012 |
[Progress in genetic studies on severe cutaneous adverse reactions to anti-epileptic drugs].
Topics: Anticonvulsants; Asian People; Carbamazepine; China; Drug Eruptions; Genetic Predisposition to Disea | 2012 |
Human leukocyte antigens and drug hypersensitivity.
Topics: Allopurinol; Carbamazepine; Dideoxynucleosides; Drug Eruptions; Drug Hypersensitivity; Genetic Predi | 2007 |
Fatal toxic epidermal necrolysis induced by carbamazepine treatment in a patient who previously had carbamazepine-induced Stevens-Johnson syndrome.
Topics: Adult; Carbamazepine; Fatal Outcome; Humans; Male; Schizophrenia; Stevens-Johnson Syndrome | 2007 |
[Stevens-Johnson syndrome secondary to carbamazepine mediated by photosensitivity].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Female; Humans; Photosensitivity Disorders; Stevens-John | 2000 |
1 trial available for carbamazepine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Comprehensive assessment of T cell receptor β repertoire in Stevens-Johnson syndrome/toxic epidermal necrolysis patients using high-throughput sequencing.
Topics: Allopurinol; Carbamazepine; Female; High-Throughput Nucleotide Sequencing; Humans; Male; Methazolami | 2019 |
191 other studies available for carbamazepine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
HLA-B*15:11 status and carbamazepine-induced severe cutaneous adverse drug reactions in HLA-B*15:02 negative Chinese.
Topics: Anticonvulsants; Carbamazepine; China; Genetic Predisposition to Disease; HLA-B Antigens; HLA-B15 An | 2022 |
Analysis of severe cutaneous adverse reactions (SCARs) in Taiwan drug-injury relief system: 18-year results.
Topics: Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Carbam | 2022 |
Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti-seizure medications.
Topics: Anticonvulsants; Carbamazepine; DNA; Genetic Predisposition to Disease; HLA-B Antigens; HLA-B15 Anti | 2022 |
Association between human leukocyte antigens and cutaneous adverse drug reactions to antiepileptics and antibiotics in the Iranian population.
Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Case-Control Studies; Ciprofloxacin; F | 2022 |
Drug-induced Stevens-Johnson syndrome: a disproportionality analysis from the pharmacovigilance database of the World Health Organization.
Topics: Allopurinol; Carbamazepine; Humans; Pharmacovigilance; Phenytoin; Retrospective Studies; Stevens-Joh | 2022 |
Carbamazepine-modified HLA-A*24:02-bound peptidome: Implication of CORO1A in skin rash.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Exanthema; Genetic Predisposition to Disease; | 2022 |
Development of label-free electrochemical impedance spectroscopy for the detection of HLA-B*15:02 and HLA-B*15:21 for the prevention of carbamazepine-induced Stevens-Johnson syndrome.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Dielectric Spectroscopy; Genetic Predisposition to | 2022 |
Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study.
Topics: Alleles; Anticonvulsants; Asian People; Benzodiazepines; Carbamazepine; Case-Control Studies; HLA-B | 2023 |
HLA-B*57:01/Carbamazepine-10,11-Epoxide Association Triggers Upregulation of the NFκB and JAK/STAT Pathways.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; HLA-B Antigens; Humans; Janus Kinases; NF-kap | 2023 |
Characterization of Drug-Specific CD4
Topics: Anticonvulsants; Carbamazepine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Hyperse | 2023 |
Carbamazepine-Induced Severe Cutaneous Adverse Drug Reactions: A 21-Year Comparison Between Children and Adults in Malaysia.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Cicatrix; Humans; Malaysia; Skin; Ste | 2023 |
Integrating real-world data in cost-effectiveness analysis of universal HLA-B*15:02 screening in Malaysia.
Topics: Adult; Benzodiazepines; Carbamazepine; Cost-Benefit Analysis; Cost-Effectiveness Analysis; HLA-B Ant | 2023 |
[Carbamazepine induced Stevens-Johnson syndrome in Han Chinese with positive
Topics: Anticonvulsants; Carbamazepine; East Asian People; Female; HLA-A Antigens; HLA-B Antigens; Humans; S | 2023 |
Stevens-johnson Syndrome and Toxic Epidermal Necrolysis: An Overview of Diagnosis, Therapy Options and Prognosis of Patients.
Topics: Aged; Carbamazepine; HLA-B Antigens; Humans; Prognosis; Quality of Life; Stevens-Johnson Syndrome | 2023 |
Pharmacogenetics to prevent hypersensitivity reactions to antiepileptic drugs: is testing performed when indicated?
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Cicatrix; HLA-B Antigens; Humans; Oxcarbazepine; Ph | 2024 |
Identification of drug-specific public TCR driving severe cutaneous adverse reactions.
Topics: Adoptive Transfer; Adult; Aged; Animals; Carbamazepine; Disease Models, Animal; Female; HLA-B15 Anti | 2019 |
Association of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis with the HLA-B75 serotype or HLA-B*15:21 allele in Filipino patients.
Topics: Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Female; HLA-B An | 2020 |
Toxicological screening reveals toxic epidermal necrolysis likely carbamazepine-induced rather than idiopathic.
Topics: Anticonvulsants; Carbamazepine; Humans; Stevens-Johnson Syndrome | 2020 |
Stevens-Johnson syndrome triggered by Levetiracetam-Caution for use with Carbamazepine.
Topics: Anticonvulsants; Asian People; Carbamazepine; Female; HLA-B15 Antigen; Humans; Levetiracetam; Steven | 2020 |
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; | 2020 |
Association of the HLA-B*15:02 allele with pure cervical lymphadenopathy induced by carbamazepine and oxcarbazepine: A case report and literature review.
Topics: Adolescent; Anticonvulsants; Carbamazepine; HLA-B Antigens; Humans; Lymphadenopathy; Male; Oxcarbaze | 2021 |
A Nationwide Study of Severe Cutaneous Adverse Reactions Based on the Multicenter Registry in Korea.
Topics: Allopurinol; Carbamazepine; Humans; Registries; Republic of Korea; Stevens-Johnson Syndrome | 2021 |
Incidence rates of severe cutaneous adverse reactions due to antiseizure medication: A nationwide study using health claims data in Korea.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Drug Hypersensiti | 2021 |
Carbamazepine-induced toxic epidermal necrolysis: the importance of HLA-B*1502 testing in at-risk populations prior to therapy initiation.
Topics: Anticonvulsants; Asian People; Carbamazepine; HLA-B Antigens; HLA-B15 Antigen; Humans; Stevens-Johns | 2021 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with anticonvulsants in a Japanese population: Matched case-control and cohort studies.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Clonazepam; Cohort Studies; Diazepam; F | 2021 |
Cost-effectiveness analysis of genotyping for HLA-B*15:02 in Indonesian patients with epilepsy using a generic model.
Topics: Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Cost-Benefit Analysis; Epilepsy; Femal | 2021 |
Towards a better understanding of adult idiopathic epidermal necrolysis: a retrospective study of 19 cases.
Topics: Adolescent; Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Retrospective Studies; Stevens- | 2021 |
Carbamazepine-induced toxic epidermal necrolysis in a patient despite testing negative for HLA B*15:02 allele.
Topics: Alleles; Anticonvulsants; Asian People; Carbamazepine; Genotype; HLA-B Antigens; Humans; Stevens-Joh | 2021 |
Assessing carbamazepine and oxcarbazepine-associated Stevens-Johnson syndrome/toxic epidermal necrolysis: Data mining the public version of the FDA adverse event reporting system.
Topics: Bayes Theorem; Carbamazepine; Data Mining; Humans; Oxcarbazepine; Stevens-Johnson Syndrome; United S | 2021 |
Cutaneous adverse reactions associated with antiseizure medication: clinical characteristics and implications in epilepsy treatment.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Exanthema; Humans; Oxcarbazepine; Stevens-Johnson Syndrome | 2021 |
Anaphylaxis to levetiracetam in an adolescent: a very rare occurence.
Topics: Adolescent; Anaphylaxis; Anticonvulsants; Carbamazepine; Child; Humans; Levetiracetam; Stevens-Johns | 2021 |
Is universal HLA-B*15:02 screening a cost-effective option in an ethnically diverse population? A case study of Malaysia.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Carbamazepine; Cost-Benefit Analysis; Efficiency; | 2017 |
HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis.
Topics: Adolescent; Amino Acid Sequence; Asian People; Carbamazepine; Computer Simulation; HLA-B15 Antigen; | 2017 |
External quality assessment for laboratory testing of HLA-B*15:02 allele in relation to carbamazepine therapy.
Topics: Carbamazepine; Contraindications, Drug; Epilepsy; Genetic Predisposition to Disease; HLA-B15 Antigen | 2018 |
HLA-A*31: 01 and HLA-B*15:02 association with Stevens-Johnson syndrome and toxic epidermal necrolysis to carbamazepine in a multiethnic Malaysian population.
Topics: Adolescent; Adult; Aged; Alleles; Asian People; Carbamazepine; Case-Control Studies; Child; Ethnicit | 2017 |
A novel multiplex polymerase chain reaction assay for detection of both HLA-A*31:01/HLA-B*15:02 alleles, which confer susceptibility to carbamazepine-induced severe cutaneous adverse reactions.
Topics: Alleles; Anticonvulsants; Base Sequence; Carbamazepine; Drug Hypersensitivity Syndrome; Gene Express | 2017 |
Association of the HLA-B alleles with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in the Javanese and Sundanese population of Indonesia: the important role of the HLA-B75 serotype.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Fema | 2017 |
The association of HLA B*15:02 allele and Stevens-Johnson syndrome/toxic epidermal necrolysis induced by aromatic anticonvulsant drugs in a South Indian population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Case-Control Studies; Ch | 2018 |
[From facial pain to toxic epidermal necrolysis: a rare complication of carbamazepine usage].
Topics: Anticonvulsants; Carbamazepine; Facial Pain; Female; Humans; Indonesia; Middle Aged; Netherlands; St | 2017 |
HLA-B*1502 haplotype screening prior to carbamazepine administration in individuals of south-east Asian ancestry nears cost-effectiveness in preventing severe cutaneous adverse drug reactions.
Topics: Anticonvulsants; Asia, Southeastern; Australia; Carbamazepine; Cost-Benefit Analysis; Genetic Testin | 2018 |
Association of HLA-A*31:01 Screening With the Incidence of Carbamazepine-Induced Cutaneous Adverse Reactions in a Japanese Population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; | 2018 |
Incidence of Stevens-Johnson syndrome following combination drug use of allopurinol, carbamazepine and phenytoin in Taiwan: A case-control study.
Topics: Adult; Aged; Allopurinol; Anticonvulsants; Carbamazepine; Case-Control Studies; Drug Combinations; E | 2018 |
Evaluation of a lymphocyte transformation test and cytokine detection assay to identify phenytoin and carbamazepine provoked DRESS or SJS/TEN in epilepsy patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Cytokines; Drug Hypersensitivity Syndrome; Epilepsy; Female; | 2018 |
Temporal trends and patterns in carbamazepine use, related severe cutaneous adverse reactions, and HLA-B*15:02 screening: A nationwide study.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepin | 2018 |
Analysis of Individual Case Safety Reports of Severe Cutaneous Adverse Reactions in Korea.
Topics: Adverse Drug Reaction Reporting Systems; Allopurinol; Anti-Bacterial Agents; Anticonvulsants; Carbam | 2019 |
HLA-B*57:01 confers genetic susceptibility to carbamazepine-induced SJS/TEN in Europeans.
Topics: Alleles; Carbamazepine; Female; Genetic Association Studies; Genetic Predisposition to Disease; HLA- | 2019 |
Intravenous immunoglobulins for delayed wound healing associated with toxic epidermal necrolysis.
Topics: Burn Units; Carbamazepine; Delayed Diagnosis; Dose-Response Relationship, Drug; Drug Administration | 2019 |
Knowledge and opinions among Canadian academic physicians regarding genetic screening to prevent severe cutaneous adverse drug reactions.
Topics: Academies and Institutes; Allopurinol; Attitude of Health Personnel; Canada; Carbamazepine; Drug Eru | 2019 |
Cost-effectiveness of screening for HLA-B*1502 prior to initiation of carbamazepine in epilepsy patients of Asian ancestry in the United States.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Cost-Benefit Analysis; Epilepsy; Genetic Predis | 2019 |
HLA-A 31:01 and HLA-B 15:02 as genetic markers for carbamazepine hypersensitivity in children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Eruptions; Drug Hypersensi | 2013 |
Cost minimization of HLA-B*1502 screening before prescribing carbamazepine in Thailand.
Topics: Alleles; Anticonvulsants; Carbamazepine; Cost-Benefit Analysis; Epilepsy; Genetic Predisposition to | 2013 |
A clinical approach to pharmacogenetics.
Topics: Carbamazepine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Genotype; Humans; | 2013 |
Combination of Steven-Johnson syndrome and neuroleptic malignant syndrome following carbamazepine therapy: a rare occurrence.
Topics: Adolescent; Carbamazepine; Humans; Male; Stevens-Johnson Syndrome | 2013 |
Economic evaluation of HLA-B*15:02 screening for carbamazepine-induced severe adverse drug reactions in Thailand.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; Epilepsy; HL | 2013 |
Stevens-Johnson syndrome and toxic epidermal necrolysis in children.
Topics: Adrenal Cortex Hormones; Allergens; Carbamazepine; Ceftriaxone; Child; Child, Preschool; Drug Erupti | 2013 |
Pharmacogenetics and its relevance to clinical practice.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Asian People; Camptothecin; Carbamazepine; Clopidogr | 2013 |
Association of carbamazepine-induced severe cutaneous drug reactions and HLA-B*1502 allele status, and dose and treatment duration in paediatric neurology patients in Singapore.
Topics: Adolescent; Alleles; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child, Preschool; | 2014 |
Genotype-phenotype association between HLA and carbamazepine-induced hypersensitivity reactions: strength and clinical correlations.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; China; Cohort Stu | 2014 |
Building pharmacogenetics into a pharmacovigilance program in Singapore: using serious skin rash as a pilot study.
Topics: Adult; Alleles; Carbamazepine; Case-Control Studies; Exanthema; Genotype; HLA-B Antigens; Humans; Mi | 2014 |
Association between the HLA-B*15:02 allele and carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Han individuals of northeastern China.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Child; | 2013 |
Association of HLA-B*1502 and *1511 allele with antiepileptic drug-induced Stevens-Johnson syndrome in central China.
Topics: Adolescent; Alleles; Anticonvulsants; Asian People; Carbamazepine; Child; Child, Preschool; China; F | 2014 |
Real-world efficiency of pharmacogenetic screening for carbamazepine-induced severe cutaneous adverse reactions.
Topics: Aged; Asian People; Carbamazepine; Costs and Cost Analysis; Drug-Related Side Effects and Adverse Re | 2014 |
Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; ATP Binding Cassette Transporter, Subfami | 2014 |
HLA-B∗ 1502 is associated with carbamazepine induced Stevens-Johnson syndrome in North Indian population.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Female; Gene Expression; HLA-B15 Antige | 2014 |
Phenytoin induced toxic epidermal necrolysis.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Humans; Male; Middle Aged; Phenytoin; Seizure | 2014 |
Association between HLA-B*15:02 allele and antiepileptic drug-induced severe cutaneous reactions in Hong Kong Chinese: a population-based study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anticonvulsants; Asian People; Carbamazepine; C | 2014 |
Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Topics: Anticonvulsants; beta Catenin; Carbamazepine; Databases, Pharmaceutical; Gene Expression Regulation; | 2015 |
Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Child; Child, Pr | 2015 |
Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.
Topics: Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Gene Expression; Haptens; HLA Antigens; Hu | 2015 |
Genetic screening for human leukocyte antigen alleles prior to carbamazepine treatment.
Topics: Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Genetic Predisposition to Disease; Gen | 2015 |
Structural modeling of HLA-B*1502/peptide/carbamazepine/T-cell receptor complex architecture: implication for the molecular mechanism of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis.
Topics: Binding Sites; Carbamazepine; HLA-B Antigens; Humans; Models, Biological; Models, Molecular; Molecul | 2016 |
Development of a simple genotyping method for the HLA-A*31:01-tagging SNP in Japanese.
Topics: Anticonvulsants; Asian People; Carbamazepine; DNA; Gene Frequency; Genetic Markers; Genotype; HLA-A | 2015 |
HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs.
Topics: Adult; Aged; Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studie | 2016 |
Early toxic epidermal necrolysis syndrome post-intra-cranial tumor resection.
Topics: Anticonvulsants; Asian People; Carbamazepine; Female; Humans; Immunoglobulins; Meningeal Neoplasms; | 2016 |
Carbamazepine-Induced Incomplete Stevens-Johnson Syndrome: Report of a Case in Children without Mycoplasma pneumoniae Infection.
Topics: Carbamazepine; Child; Cytochrome P-450 CYP3A Inducers; Humans; Male; Mycoplasma pneumoniae; Pneumoni | 2015 |
Toxic epidermal necrolysis in patient with malignant astrocytoma.
Topics: Astrocytoma; Bacterial Outer Membrane Proteins; Brain Neoplasms; Carbamazepine; Epilepsy; Female; Hu | 2016 |
Use of the Biopharmaceutics Drug Disposition Classification System (BDDCS) to Help Predict the Occurrence of Idiosyncratic Cutaneous Adverse Drug Reactions Associated with Antiepileptic Drug Usage.
Topics: Anticonvulsants; Asian People; Biopharmaceutics; Carbamazepine; HLA-B Antigens; Humans; Stevens-John | 2016 |
Carbamazepine induced Stevens-Johnson syndrome.
Topics: Adult; Asian People; Carbamazepine; Genetic Predisposition to Disease; HLA-B15 Antigen; Humans; Male | 2016 |
The HLA-B*15:02 allele in a Spanish Romani patient with carbamazepine-induced Stevens-Johnson syndrome.
Topics: Adolescent; Alleles; Carbamazepine; HLA-B Antigens; Humans; Male; Risk Factors; Stevens-Johnson Synd | 2016 |
A study of HLA-B∗15:02 in a Sri Lankan population: Implications for pharmacogenomic testing.
Topics: Carbamazepine; Cohort Studies; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; H | 2016 |
Coupling Genotyping and Computational Modeling in Prediction of Anti-epileptic Drugs that cause Stevens Johnson Syndrome and Toxic Epidermal Necrolysis for Carrier of HLA-B*15:02.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Female; Genotype; Heterozygote; HLA-B Antigens; H | 2016 |
Carbamazepine and oxcarbazepine: reflections after an oxcarbazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis overlap.
Topics: Aged, 80 and over; Analgesics; Anticonvulsants; Blister; Carbamazepine; Female; Humans; Oxcarbazepin | 2016 |
Improving drug safety with a systems pharmacology approach.
Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Analgesics, Non-Narcotic; Anticonvulsants; C | 2016 |
Validation of a novel real-time PCR assay for detection of HLA-B*15:02 allele for prevention of carbamazepine - Induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis in individuals of Asian ancestry.
Topics: Alleles; Asian People; Carbamazepine; Genetic Predisposition to Disease; Genetic Testing; Genotype; | 2016 |
Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Child; Chi | 2017 |
A study of HLA-B*15:02 in 9 different Chinese ethnics: Implications for carbamazepine related SJS/TEN.
Topics: Adult; Alleles; Anticonvulsants; Asian People; Blood Donors; Carbamazepine; China; Contraindications | 2017 |
[Stevens-Johnson syndrome/toxic epidermal necrolysis after initiation of carbamazepine in a HLA-B*15:02 gene carrier – screening in risk patients is recommended].
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Epilepsy, Generalized; Female; HLA-B15 Antigen; | 2017 |
Acute generalised exanthematous pustulosis and toxic epidermal necrolysis induced by carbamazepine.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Exanthema; Female; Humans; Skin Diseases, Ves | 2008 |
Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Genetic Predisposition t | 2008 |
Oxcarbazepine-induced Stevens-Johnson syndrome in a patient with HLA-B*1502 genotype.
Topics: Anticonvulsants; Carbamazepine; Genotype; HLA-B Antigens; Humans; Male; Middle Aged; Oxcarbazepine; | 2009 |
The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study.
Topics: Acetaminophen; Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Case-Contr | 2008 |
For Asians only? The perils of ancestry-based drug prescribing.
Topics: Alleles; Anticonvulsants; Asian People; Carbamazepine; Drug Labeling; HLA-B Antigens; HLA-B15 Antige | 2008 |
Carbamazepine, HLA-B*1502 and risk of Stevens-Johnson syndrome and toxic epidermal necrolysis: US FDA recommendations.
Topics: Alleles; Asian People; Carbamazepine; Forecasting; Gene Frequency; Health Planning Guidelines; HLA-B | 2008 |
HLA-B allele associations with certain drugs are not confirmed in Japanese patients with severe cutaneous drug reactions.
Topics: Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; Chemical and Drug Induced Liver | 2008 |
Human leukocyte antigen genotypes in carbamazepine-induced severe cutaneous adverse drug response in Japanese patients.
Topics: Carbamazepine; Drug Eruptions; Gene Frequency; Genotype; HLA-A Antigens; Humans; Stevens-Johnson Syn | 2008 |
Toxic epidermal necrolysis in a child after carbamazepine dosage increment.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Diagnosis, Differential; Humans; Male; Stevens-Joh | 2009 |
eComment: Plasmapheresis for near-fatal heparin-induced thrombocytopenia.
Topics: Adult; Antibodies; Anticoagulants; Antimanic Agents; Carbamazepine; Fatal Outcome; Heparin; Humans; | 2009 |
Oxcarbazepine-induced Stevens-Johnson syndrome: a case report.
Topics: Anticonvulsants; Carbamazepine; Child; Genotype; HLA-B Antigens; HLA-B15 Antigen; Humans; Male; Oxca | 2009 |
HLA class I markers in Japanese patients with carbamazepine-induced cutaneous adverse reactions.
Topics: Adolescent; Adult; Alleles; Asian People; Carbamazepine; Child; Drug Eruptions; Drug Hypersensitivit | 2010 |
Prevention of severe cutaneous adverse drug reactions: the emerging value of pharmacogenetic screening.
Topics: Adult; Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; China; Cyclosporine; Drug | 2010 |
Fatal carbamazepine induced fulminant eosinophilic (hypersensitivity) myocarditis: emphasis on anatomical and histological characteristics, mechanisms and genetics of drug hypersensitivity and differential diagnosis.
Topics: Adult; Anticonvulsants; Carbamazepine; Diagnosis, Differential; Eosinophilia; Eosinophils; Forensic | 2010 |
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anticonvulsants; Asian People; Carbamazepine; C | 2010 |
Association between HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in a Thai population.
Topics: Adult; Aged; Anticonvulsants; Asian People; Carbamazepine; Child; Female; Genetic Markers; Genetic P | 2010 |
Stratification of the risk of serious allergic cutaneous reactions with therapeutic management of trigeminal neuralgia.
Topics: Anticonvulsants; Asian People; Carbamazepine; China; Drug Hypersensitivity; Gene Frequency; HLA-B An | 2011 |
HLA-B* 1502 screening: time to clinical practice.
Topics: Alleles; Anticonvulsants; Asian People; Carbamazepine; Epilepsy; Genetic Markers; Genetic Testing; G | 2010 |
Pharmacogenetic screening.
Topics: Carbamazepine; Drug Hypersensitivity; Humans; Pharmacogenetics; Stevens-Johnson Syndrome | 2010 |
Letter: HLA B*1502 allele association with oxcarbamazepine-induced skin reactions in epilepsy patient from India.
Topics: Alleles; Anticonvulsants; Asian People; Carbamazepine; Child; Drug Eruptions; Epilepsy; Female; HLA- | 2009 |
Association between carbamazepine-induced cutaneous adverse drug reactions and the HLA-B*1502 allele among patients in central China.
Topics: Adolescent; Adult; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child | 2010 |
Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7.
Topics: Acetaminophen; Acute Generalized Exanthematous Pustulosis; Adult; Anti-Inflammatory Agents; Antidepr | 2010 |
Early gynaecological assessment following Stevens-Johnson syndrome/toxic epidermal necrolysis.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Stevens-Johnson Syndrome; Tissue Adhesions; V | 2010 |
HLA-B*1502 allele associated with carbamazepine-induced epidermal necrolysis.
Topics: Adolescent; Alleles; Analgesics, Non-Narcotic; Carbamazepine; Dystonia; HLA-B Antigens; HLA-B15 Anti | 2010 |
HLA-B*1511 is a risk factor for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients.
Topics: Adolescent; Adult; Aged; Asian People; Carbamazepine; Child; Family; Female; Genotype; HLA-B Antigen | 2010 |
Association of HLA-B*1502 allele with carbamazepine-induced toxic epidermal necrolysis and Stevens-Johnson syndrome in the multi-ethnic Malaysian population.
Topics: Anticonvulsants; Asian People; Carbamazepine; Genetic Markers; Genetic Predisposition to Disease; HL | 2011 |
Severe bullous hypersensitivity reactions after exposure to carbamazepine in a Han-Chinese child with a positive HLA-B*1502 and negative in vitro toxicity assays: evidence for different pathophysiological mechanisms.
Topics: Anticonvulsants; Asian People; Blood Platelets; Carbamazepine; Case-Control Studies; Child; China; D | 2011 |
Association between HLA-B*1502 allele and carbamazepine-induced severe cutaneous adverse reactions in Han people of southern China mainland.
Topics: Adult; Anticonvulsants; Carbamazepine; China; DNA; Drug Eruptions; Female; Genotype; HLA-B Antigens; | 2011 |
Strong association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in mainland Han Chinese patients.
Topics: Adult; Alleles; Anticonvulsants; Carbamazepine; China; Genetic Predisposition to Disease; Genotype; | 2011 |
[A woman with skin lesions over her whole body].
Topics: Adult; Anti-Inflammatory Agents; Carbamazepine; Female; Humans; Prednisone; Stevens-Johnson Syndrome | 2011 |
Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Child; Chi | 2011 |
Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Child; Chi | 2011 |
Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Child; Chi | 2011 |
Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Child; Chi | 2011 |
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Exanthema; Genome-Wide Association Study; Gen | 2011 |
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Exanthema; Genome-Wide Association Study; Gen | 2011 |
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Exanthema; Genome-Wide Association Study; Gen | 2011 |
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Exanthema; Genome-Wide Association Study; Gen | 2011 |
HLA-B*1502 strongly predicts carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Thai patients with neuropathic pain.
Topics: Adult; Aged; Alleles; Analgesics, Non-Narcotic; Carbamazepine; Case-Control Studies; Drug-Related Si | 2012 |
HLA-B*1502 screening and toxic effects of carbamazepine.
Topics: Anticonvulsants; Asian People; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; Genot | 2011 |
HLA-B*1502 screening and toxic effects of carbamazepine.
Topics: Anticonvulsants; Asian People; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; HLA-B | 2011 |
Carbamazepine-induced severe cutaneous adverse reactions and HLA genotypes in Koreans.
Topics: Adult; Aged; Anticonvulsants; Asian People; Carbamazepine; Drug Eruptions; Epilepsy; Female; Gene Fr | 2011 |
Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome.
Topics: Adult; Anticonvulsants; Biomarkers; Carbamazepine; Cell Separation; Cells, Cultured; Complementarity | 2011 |
Frequency of the HLA-B*1502 allele contributing to carbamazepine-induced hypersensitivity reactions in a cohort of Malaysian epilepsy patients.
Topics: Adolescent; Adult; Alleles; Asian People; Carbamazepine; Child; Child, Preschool; Cohort Studies; Dr | 2011 |
Severe cutaneous adverse reactions to antiepileptic drugs in Asians.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Exanthema; Female; Follow-Up Studies; Humans; L | 2011 |
Drug-induced epidermal necrolysis: Important new piece to end the puzzle.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; HLA-B Antigens; Humans; Male; Peptide | 2011 |
[Case-report: toxic epidermal necrolysis].
Topics: Adult; Anticonvulsants; Burn Units; Carbamazepine; Critical Care; Female; Humans; Prognosis; Stevens | 2011 |
HLA-A31 strongly associates with carbamazepine-induced adverse drug reactions but not with carbamazepine-induced lymphocyte proliferation in a Japanese population.
Topics: Adult; Aged; Amino Acid Sequence; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies | 2012 |
Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.
Topics: Adolescent; Adult; Aged; Antigen Presentation; Carbamazepine; Cell Line; Child; Drug Hypersensitivit | 2012 |
Association between HLA and Stevens-Johnson syndrome induced by carbamazepine in Southern Han Chinese: genetic markers besides B*1502?
Topics: Adolescent; Adult; Alleles; Asian People; Carbamazepine; Child; China; Cohort Studies; Female; Genet | 2012 |
Genetics and the potential for predictive tests in adverse drug reactions.
Topics: Allopurinol; Anti-Bacterial Agents; Anti-HIV Agents; Anticonvulsants; Antimetabolites; Biomarkers; C | 2012 |
Rhabdomyolysis as a potential complication of carbamazepine-induced toxic epidermal necrolysis.
Topics: Adult; Antimanic Agents; Carbamazepine; Fatal Outcome; Humans; Male; Rhabdomyolysis; Schizophrenia; | 2012 |
HLA-B*1502 screening in carbamazepine and lamotrigine candidates of Asian background.
Topics: Antimanic Agents; Asian People; Carbamazepine; Genetic Predisposition to Disease; Genetic Testing; H | 2012 |
Cost-effectiveness of HLA-B*1502 genotyping in adult patients with newly diagnosed epilepsy in Singapore.
Topics: Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Cost-Benefit Analysis; Decision Making | 2012 |
Use of carbamazepine and lamotrigine in a Taiwanese diabetic patient with bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Diabetes Complications; Drug Therapy, Combination | 2012 |
Stevens Johnson syndrome--an adverse drug reaction occurred after uncomplicated removal of an intracerebral cavernous hemangioma.
Topics: Adolescent; Anticonvulsants; Brain Neoplasms; Carbamazepine; Drug Eruptions; Epilepsies, Partial; Ep | 2013 |
Development of a simple method for detection of the HLA-A*31:01 allele.
Topics: Alleles; Asian People; Carbamazepine; Genotyping Techniques; HLA-A Antigens; Humans; Polymerase Chai | 2013 |
[Drug-induced toxic epidermal necrolysis with involvement of the intestinal and respiratory tract. A case report].
Topics: Alcoholism; Anticonvulsants; Burn Units; Carbamazepine; Humans; Intestinal Diseases; Male; Middle Ag | 2002 |
Treatment of toxic epidermal necrolysis with intravenous immunoglobulin.
Topics: Adult; Antidepressive Agents, Second-Generation; Antimanic Agents; Carbamazepine; Cyclohexanols; Dep | 2003 |
[Erythema multiforme caused by carbamazepine].
Topics: Anticonvulsants; Bipolar Disorder; Borderline Personality Disorder; Carbamazepine; Dose-Response Rel | 2004 |
Spectrum of anticonvulsant hypersensitivity syndrome: controversy of treatment.
Topics: Anticonvulsants; Carbamazepine; Female; Glucocorticoids; Humans; Infant; Infusions, Intravenous; Met | 2004 |
Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: a case-control study.
Topics: Adult; Allopurinol; Analgesics, Non-Narcotic; Anticonvulsants; Antimetabolites; Carbamazepine; Case- | 2005 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotri | 2005 |
Toxic epidermal necrolysis associated with concomitant use of lamotrigine and carbamazepine: a case report.
Topics: Adult; Carbamazepine; Combined Modality Therapy; Drug Interactions; Drug Therapy, Combination; Femal | 2005 |
Case records of the Massachusetts General Hospital. Case 34-2005. A 10-year-old girl with a bullous skin eruption and acute respiratory failure.
Topics: Carbamazepine; Child; Diagnosis, Differential; Female; Humans; Lung; Radiography; Respiratory Distre | 2005 |
Stevens-Johnson syndrome (SJS) leading to resolution of mania.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Drug | 2006 |
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Drug Hypersensitivity; Exanthema; Genetic Pred | 2006 |
Diagnostic role of soluble fas ligand secretion by peripheral blood mononuclear cells from patients with previous drug-induced blistering disease: a pilot study.
Topics: Adult; Carbamazepine; Fas Ligand Protein; Female; Humans; Leukocytes, Mononuclear; Male; Membrane Gl | 2006 |
Role of biological membranes in the management of Stevens Johnson syndrome--Indian experience.
Topics: Anticonvulsants; Biological Dressings; Carbamazepine; Child; Humans; Male; Stevens-Johnson Syndrome | 2007 |
Stevens-Johnson syndrome due to concomitant use of lamotrigine and valproic acid.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrig | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.
Topics: Carbamazepine; HLA-B Antigens; Humans; Mass Spectrometry; Peptides; Stevens-Johnson Syndrome | 2007 |
Investigation into the multidimensional genetic basis of drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbamazepine; Child; Female; Genetic Predisposition to | 2007 |
[Fluid loss in toxic epidermal necrolysis].
Topics: Adult; Carbamazepine; Female; Fluid Therapy; Humans; Male; Stevens-Johnson Syndrome; Water-Electroly | 1984 |
Carbamazepine ('Tegretol') and toxic epidermal necrolysis: report of three cases with histopathological observations.
Topics: Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Skin; Stevens-Johnson Syndrome | 1982 |
The anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Bronchial Diseases; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Fa | 1993 |
Carbamazepine-induced Stevens-Johnson syndrome in a child.
Topics: Anti-Bacterial Agents; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy, Generalized; Human | 1995 |
Severe adverse cutaneous reactions to drugs.
Topics: Brain Neoplasms; Carbamazepine; Drug Eruptions; Humans; Radiotherapy; Stevens-Johnson Syndrome | 1995 |
Investigation of mechanisms in toxic epidermal necrolysis induced by carbamazepine.
Topics: Adult; Carbamazepine; Cytotoxicity, Immunologic; Erythema Multiforme; Female; Humans; Lymphocyte Act | 1994 |
Carbamazepine-induced Stevens-Johnson syndrome.
Topics: Adult; Bipolar Disorder; Carbamazepine; Debridement; Drug Eruptions; Female; Humans; Stevens-Johnson | 1993 |
[Stevens-Johnson syndrome secondary to carbamazepine].
Topics: Adult; Carbamazepine; Epilepsy; Humans; Male; Stevens-Johnson Syndrome | 1993 |
Fatal course of toxic epidermal necrolysis under treatment with lamotrigine.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Fatal Outcome; Humans; Lamotrigine; Male; Middle | 1995 |
Hyponatremia and Stevens-Johnson syndrome in a patient receiving carbamazepine.
Topics: Adult; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, | 1995 |
Toxic epidermal necrolysis treated with cyclosporin and granulocyte colony stimulating factor.
Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Cyclosporine; Female; Filgrastim; Granulocyte Colony | 1997 |
[Generalized Lyell syndrome due to carbamazepine].
Topics: Anticonvulsants; Carbamazepine; Child; Female; Humans; Stevens-Johnson Syndrome | 1997 |
Toxic epidermal necrolysis and cyclosporin.
Topics: Analgesics, Non-Narcotic; Carbamazepine; Cyclosporins; Humans; Immunosuppressive Agents; Male; Middl | 1997 |
Covalent binding of carbamazepine reactive metabolites to P450 isoforms present in the skin.
Topics: Adult; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme System; Female; Humans; In Vitro Tech | 1998 |
Skin reactions to carbamazepine.
Topics: Adult; Anticonvulsants; Antimanic Agents; Carbamazepine; CD4-Positive T-Lymphocytes; CD8-Positive T- | 1999 |
Are carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis more common in nonepileptic patients?
Topics: Anticonvulsants; Carbamazepine; Comorbidity; Epilepsy; Humans; Prevalence; Stevens-Johnson Syndrome | 1999 |
Anticonvulsant-induced toxic epidermal necrolysis: monitoring the immunologic response.
Topics: Adult; Antibody Formation; Anticonvulsants; Blood Cells; Carbamazepine; CD3 Complex; Cytokines; E-Se | 2000 |
[Stevens-Johnson syndrome with transition to toxic epidermal necrolysis after carbamazepine administration, heroin and alcohol abuse].
Topics: Adult; Alcoholism; Anticonvulsants; Carbamazepine; Heroin Dependence; Humans; Male; Risk Factors; Sk | 1999 |
Carbamazepine-induced Stevens-Johnson syndrome treated with IV steroids and IVIG.
Topics: Adolescent; Anti-Inflammatory Agents; Anticonvulsants; Carbamazepine; Female; Humans; Immunoglobulin | 2000 |
Valproate and other anticonvulsants for psychiatric disorders.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar | 2000 |
Stevens-Johnson syndrome due to carbamazepine.
Topics: Adult; Bipolar Disorder; Carbamazepine; Drug Eruptions; Female; Humans; Male; Stevens-Johnson Syndro | 2000 |
Stevens-Johnson syndrome due to carbamazepine.
Topics: Antimanic Agents; Carbamazepine; Humans; Stevens-Johnson Syndrome; Treatment Outcome | 2001 |
Efficacy of early immunosuppressive therapy in a child with carbamazepine-associated vanishing bile duct and Stevens-Johnson syndromes.
Topics: Bile Duct Diseases; Bile Ducts, Intrahepatic; Carbamazepine; Child, Preschool; Cholestasis; Hepatiti | 2002 |
Toxic epidermal necrolysis secondary to carbamazepine in a patient with human immunodeficiency virus infection.
Topics: Adrenal Cortex Hormones; Adult; Analgesics, Non-Narcotic; Carbamazepine; Follow-Up Studies; HIV Infe | 2001 |
Mucocutaneous eruptions due to antiepileptic drug therapy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; | 1979 |
[Lyell's syndrome as a more severe form of allergic reaction to phinlepsin (carbamazepine)].
Topics: Carbamazepine; Humans; Male; Middle Aged; Stevens-Johnson Syndrome; Trigeminal Neuralgia | 1976 |
Drug-induced febrile mucocutaneous syndrome with a survey of the literature.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Female; Humans; Infant; Male; Middl | 1975 |
[Electroconvulsive therapy in treatment of acute life threatening catatonia in toxic epidermal necrolysis (Lyell syndrome)].
Topics: Adult; Bipolar Disorder; Carbamazepine; Catatonia; Drug Therapy, Combination; Electroconvulsive Ther | 1992 |
Lyell syndrome and lethal catatonia: a case for ECT.
Topics: Adult; Bipolar Disorder; Carbamazepine; Catatonia; Electroconvulsive Therapy; Female; Humans; Steven | 1992 |
Plasma exchange (PE) treatment in drug-induced toxic epidermal necrolysis (TEN).
Topics: Aged; Allopurinol; Amoxicillin; Carbamazepine; Child; Ciprofloxacin; Humans; Male; Mefenamic Acid; M | 1991 |
Stevens-Johnson syndrome in neuroleptic-carbamazepine combination.
Topics: Adult; Antipsychotic Agents; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Female; Hu | 1990 |
Stevens-Johnson syndrome in a patient receiving cranial irradiation and carbamazepine.
Topics: Adult; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; Female; Humans; Radiotherapy; Stev | 1990 |
Erythema multiforme major in a patient treated with carbamazepine.
Topics: Adult; Bipolar Disorder; Carbamazepine; Humans; Male; Stevens-Johnson Syndrome | 1987 |
Lymphocyte transformation test in drug-induced toxic epidermal necrolysis.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dipyrone; Drug Combinations; Female; Flurbiprofen; Hu | 1985 |
[Lyell's syndrome or acute epidermal necrosis (apropos of 2 cases)].
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Carbamazepine; Female; Fluphenazine; Humans; Iatrogenic Di | 1972 |
Diphenylhydantoin.
Topics: Affective Symptoms; Arrhythmias, Cardiac; Ataxia; Carbamazepine; Central Nervous System Diseases; Ch | 1971 |
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocyt | 1974 |