Page last updated: 2024-10-24

carbamazepine and Spinal Cord Injuries

carbamazepine has been researched along with Spinal Cord Injuries in 13 studies

Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.

Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Research Excerpts

ExcerptRelevanceReference
"Various pharmacologic approaches have been advocated for treatment of chronic pain in spinal cord injury, including the use of either anticonvulsants or antidepressants."5.28Amitriptyline and carbamazepine in the treatment of dysesthetic pain in spinal cord injury. ( Haddox, JD; Lindblom, LB; Sandford, PR, 1992)
"Oxcarbazepine was significantly more effective for patients without evoked pain than in those with it for electrical, burning, and pricking pain."2.82Symptom-Based Treatment of Neuropathic Pain in Spinal Cord-Injured Patients: A Randomized Crossover Clinical Trial. ( Lee, SH; Min, K; Oh, Y; Ryu, JS, 2016)
"Spinal cord ischemia was induced by infrarenal aortic crossclamp for 25 minutes in both groups."1.35Effects of carbamazepine on spinal cord ischemia. ( Bahadir Inan, M; Besalti, O; Elhan, AH; Erdemli, E; Eryilmaz, S; Kaya, B; Ozcinar, E; Ozyurda, U; Sirin, YS; Sirlak, M; Tasoz, R; Yazicioglu, L, 2008)
"Previous studies have demonstrated that pharmacokinetic behavior of several drugs such as paracetamol, theophylline, and aminoglycosides are significantly altered in patients with spinal cord injury."1.33The influence of experimental spinal cord injury on carbamazepine pharmacokinetics. ( Ansari, M; Karamousian, S; Reihani-Kermani, H, 2006)
"Various pharmacologic approaches have been advocated for treatment of chronic pain in spinal cord injury, including the use of either anticonvulsants or antidepressants."1.28Amitriptyline and carbamazepine in the treatment of dysesthetic pain in spinal cord injury. ( Haddox, JD; Lindblom, LB; Sandford, PR, 1992)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's3 (23.08)18.2507
2000's5 (38.46)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Yang, X1
Zhang, Y1
Yu, H1
Sun, J1
He, Y1
Chen, FC1
Shao, HL1
Han, FL1
Min, K1
Oh, Y1
Lee, SH1
Ryu, JS1
Sirlak, M1
Eryilmaz, S1
Bahadir Inan, M1
Sirin, YS1
Besalti, O1
Yazicioglu, L1
Ozcinar, E1
Erdemli, E1
Tasoz, R1
Elhan, AH1
Kaya, B1
Ozyurda, U1
Jiang, CJ1
Tan, YC1
Yang, YJ1
Zhang, EZ1
Liu, J1
Yao, SQ1
Yu, JL1
Salinas, FA1
Lugo, LH1
García, HI1
Vogel, LC1
Anderson, CJ1
Iriarte, J1
Narbona, J1
García del Barrio, L1
Artieda, J1
Reihani-Kermani, H1
Ansari, M1
Karamousian, S1
Previdi, P1
Buzzi, P1
Gallien, P1
Nicolas, B1
Robineau, S1
Lebot, MP1
Brissot, R1
Sandford, PR1
Lindblom, LB1
Haddox, JD1
Bussel, B1
Roby-Brami, A1
Azouvi, P1
Biraben, A1
Yakovleff, A1
Held, JP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Symptom-Based Treatment for Neuropathic Pain in Spinal Cord Injured Patients, Randomized Clinical Trial[NCT02180880]Phase 463 participants (Actual)Interventional2012-11-30Completed
Management of Chronic Pain in Rehabilitation Project I - Management of Chronic Pain in Persons With Spinal Cord Injury[NCT00006428]Phase 4100 participants Interventional1996-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for carbamazepine and Spinal Cord Injuries

ArticleYear
Symptom-Based Treatment of Neuropathic Pain in Spinal Cord-Injured Patients: A Randomized Crossover Clinical Trial.
    American journal of physical medicine & rehabilitation, 2016, Volume: 95, Issue:5

    Topics: Calcium Channel Blockers; Carbamazepine; Cross-Over Studies; Evoked Potentials; Female; Humans; Male

2016
Efficacy of early treatment with carbamazepine in prevention of neuropathic pain in patients with spinal cord injury.
    American journal of physical medicine & rehabilitation, 2012, Volume: 91, Issue:12

    Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Carbamazepine; Female; Health Status Indicators;

2012

Other Studies

11 other studies available for carbamazepine and Spinal Cord Injuries

ArticleYear
Efficacy of Pregabalin in Neuropathic Pain after Spinal Cord Injury.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:1

    Topics: Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Carbamazepine; Female; Humans; Male; Middle Aged;

2020
A pilot study of neuromuscular electrical stimulation for neuropathic pain caused by spinal cord injury.
    Medicine, 2018, Volume: 97, Issue:31

    Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Combined Modality Therapy; Electric Stimulation Ther

2018
Effects of carbamazepine on spinal cord ischemia.
    The Journal of thoracic and cardiovascular surgery, 2008, Volume: 136, Issue:4

    Topics: Animals; Biopsy, Needle; Carbamazepine; Disease Models, Animal; Female; Immunohistochemistry; Male;

2008
[Sequential drugs treatment for central pain following spinal cord injury].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2009, Volume: 22, Issue:6

    Topics: Adult; Amitriptyline; Carbamazepine; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female;

2009
Self-injurious behavior in children and adolescents with spinal cord injuries.
    Spinal cord, 2002, Volume: 40, Issue:12

    Topics: Acetates; Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Fe

2002
Diaphragmatic flutter after spinal cord trauma in a child.
    Neurology, 2005, Dec-13, Volume: 65, Issue:11

    Topics: Accidental Falls; Anticonvulsants; Carbamazepine; Child; Diaphragm; Efferent Pathways; Electromyogra

2005
The influence of experimental spinal cord injury on carbamazepine pharmacokinetics.
    Archives of Iranian medicine, 2006, Volume: 9, Issue:3

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Carbamazepine; Chromatography, High Pressur

2006
Carbamazepine for paroxysmal dystonia due to spinal cord lesions.
    Italian journal of neurological sciences, 1993, Volume: 14, Issue:4

    Topics: Carbamazepine; Chronic Disease; Dystonia; Humans; Multiple Sclerosis; Spinal Cord Injuries

1993
The reflex sympathetic dystrophy syndrome in patients who have had a spinal cord injury.
    Paraplegia, 1995, Volume: 33, Issue:12

    Topics: Adult; Analgesics, Non-Narcotic; Antidepressive Agents, Tricyclic; Arthrography; Calcitonin; Carbama

1995
Amitriptyline and carbamazepine in the treatment of dysesthetic pain in spinal cord injury.
    Archives of physical medicine and rehabilitation, 1992, Volume: 73, Issue:3

    Topics: Adult; Amitriptyline; Carbamazepine; Female; Humans; Pain; Spinal Cord Injuries

1992
Myoclonus in a patient with spinal cord transection. Possible involvement of the spinal stepping generator.
    Brain : a journal of neurology, 1988, Volume: 111 ( Pt 5)

    Topics: Adult; Carbamazepine; Electric Stimulation; Electromyography; Humans; Magnetic Resonance Imaging; Ma

1988